hydroxychloroquine has been researched along with Fabry Disease in 9 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Fabry Disease: An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapy with cationic amphiphilic drugs (Amiodarone or hydroxychloroquine) may result in biochemically and ultrastructurally similar lipid inclusions in many cells also affected by Fabry disease (FD)." | 4.02 | Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis. ( Albertón, V; Barriales-Villa, R; Di Pietrantonio, S; Durand, C; Fernandez, A; Frabasil, J; Larrañaga-Moreira, J; Politei, J; Schenone, AB; Velasquez Rivas, D, 2021) |
| "Proteinuria is one of the most typical manifestations of kidney involvement in Systemic Lupus Erythematosus (SLE)." | 1.62 | "Protenuria in SLE: Is it always lupus?" ( Alessandri, C; Celia, AI; Cerbelli, B; Conti, F; d'Amati, G; Diomedi-Camassei, F; Leuzzi, V; Priori, R; Scrivo, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Hanneman, K | 1 |
| Alberdi, HV | 1 |
| Karur, GR | 1 |
| Tselios, K | 1 |
| Harvey, PJ | 1 |
| Gladman, DD | 1 |
| Akhtari, S | 1 |
| Osuntokun, T | 1 |
| Wald, RM | 1 |
| Thavendiranathan, P | 1 |
| Butany, J | 1 |
| Urowitz, MB | 1 |
| Kadosawa, K | 1 |
| Morikawa, T | 1 |
| Konishi, Y | 1 |
| Politei, J | 1 |
| Frabasil, J | 1 |
| Durand, C | 1 |
| Di Pietrantonio, S | 1 |
| Fernandez, A | 1 |
| Albertón, V | 1 |
| Velasquez Rivas, D | 1 |
| Barriales-Villa, R | 1 |
| Larrañaga-Moreira, J | 1 |
| Schenone, AB | 1 |
| Celia, AI | 1 |
| Priori, R | 1 |
| Cerbelli, B | 1 |
| Diomedi-Camassei, F | 1 |
| Leuzzi, V | 1 |
| Scrivo, R | 1 |
| Alessandri, C | 1 |
| d'Amati, G | 1 |
| Conti, F | 1 |
| Sperati, CJ | 1 |
| Rosenberg, AZ | 1 |
| Serre, J | 1 |
| Buob, D | 1 |
| Boffa, JJ | 1 |
| Chatre, C | 1 |
| Filippi, N | 1 |
| Roubille, F | 1 |
| Pers, YM | 1 |
| Bracamonte, ER | 1 |
| Kowalewska, J | 1 |
| Starr, J | 1 |
| Gitomer, J | 1 |
| Alpers, CE | 1 |
| Woywodt, A | 1 |
| Hellweg, S | 1 |
| Schwarz, A | 1 |
| Schaefer, RM | 1 |
| Mengel, M | 1 |
9 other studies available for hydroxychloroquine and Fabry Disease
| Article | Year |
|---|---|
Antimalarial-Induced Cardiomyopathy Resembles Fabry Disease on Cardiac MRI.
Topics: Adult; Aged; Antimalarials; Biopsy; Cardiomyopathies; Cardiotoxicity; Chloroquine; Diagnosis, Differ | 2020 |
Zebra bodies without Fabry disease or hydroxychloroquine.
Topics: Adult; Antibodies, Antiphospholipid; Antirheumatic Agents; Fabry Disease; Humans; Hydroxychloroquine | 2021 |
Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis.
Topics: Adult; Aged; Amiodarone; Fabry Disease; Glycolipids; Humans; Hydroxychloroquine; Incidental Findings | 2021 |
"Protenuria in SLE: Is it always lupus?"
Topics: Antirheumatic Agents; Biopsy; Diagnosis, Differential; Enzyme Replacement Therapy; Fabry Disease; Fe | 2021 |
Hydroxychloroquine-induced mimic of renal Fabry disease.
Topics: Adult; Antirheumatic Agents; Biopsy; Diagnosis, Differential; Fabry Disease; Female; Humans; Hydroxy | 2018 |
Hydroxychloroquine-induced podocytopathy mimicking Fabry disease.
Topics: Adult; Antirheumatic Agents; Diagnosis, Differential; Fabry Disease; Female; Humans; Hydroxychloroqu | 2019 |
Heart Involvement in a Woman Treated with Hydroxychloroquine for Systemic Lupus Erythematosus Revealing Fabry Disease.
Topics: Biopsy, Needle; Cardiomyopathies; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Ad | 2016 |
Iatrogenic phospholipidosis mimicking Fabry disease.
Topics: alpha-Galactosidase; Antirheumatic Agents; Diagnosis, Differential; DNA Mutational Analysis; Epithel | 2006 |
A wild zebra chase.
Topics: Aged; Biopsy; Diagnosis, Differential; Fabry Disease; Female; Humans; Hydroxychloroquine; Iatrogenic | 2007 |