Page last updated: 2024-10-28

hydroxychloroquine and Erythema

hydroxychloroquine has been researched along with Erythema in 35 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"severe distinctive cutaneous drug reaction, generalized pustular figurate erythema, closely linked with hydroxychloroquine (HCQ), has been documented."9.22Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review. ( Al Muqarrab, F; Almohssen, AA; Schwartz, RA, 2022)
"This study confirms the efficacy of patch tests in patients with delayed hypersensitivity reactions to hydroxychloroquine."8.31[Multiform exudative erythema caused by hydroxychloroquine, diagnosed by epicutaneous tests: A case report]. ( Castro-Jiménez, A; Florido López, F; Gratacós-Gómez, AR, 2023)
"Annular erythema is one of the cutaneous manifestations of Sjögren's syndrome (SS)."5.62Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome. ( Amagai, M; Arakawa, H; Miyamoto, J; Murakami, K; Sujino, K; Tanaka, R; Tanese, K; Tanikawa, A, 2021)
"severe distinctive cutaneous drug reaction, generalized pustular figurate erythema, closely linked with hydroxychloroquine (HCQ), has been documented."5.22Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review. ( Al Muqarrab, F; Almohssen, AA; Schwartz, RA, 2022)
"This study confirms the efficacy of patch tests in patients with delayed hypersensitivity reactions to hydroxychloroquine."4.31[Multiform exudative erythema caused by hydroxychloroquine, diagnosed by epicutaneous tests: A case report]. ( Castro-Jiménez, A; Florido López, F; Gratacós-Gómez, AR, 2023)
" The antimalarial hydroxychloroquine has a rapid and reliable effect in reticular erythematous mucinosis."3.72Treatment of scleromyxoedema with hydroxychloroquine. ( Becker, JC; Bröcker, EB; Kahaly, GJ; Lurz, C; Terheyden, P, 2003)
"Annular erythema is one of the cutaneous manifestations of Sjögren's syndrome (SS)."1.62Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome. ( Amagai, M; Arakawa, H; Miyamoto, J; Murakami, K; Sujino, K; Tanaka, R; Tanese, K; Tanikawa, A, 2021)
"Pruritus was the most common initial symptom reported in both groups, while periungual erythema and Gottron's papules were the most common skin presentations."1.39A comparative study of clinical characteristics, work-up, treatment, and association to malignancy in dermatomyositis between two tertiary skin centers in the USA and Singapore. ( Carroll, C; Chan, YH; Jorizzo, J; Kannagra, A; LoSicco, K; Manabat, CG; Ng, P; Tan, A; Yosipovitch, G, 2013)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19907 (20.00)18.7374
1990's2 (5.71)18.2507
2000's5 (14.29)29.6817
2010's9 (25.71)24.3611
2020's12 (34.29)2.80

Authors

AuthorsStudies
Appelt, LM1
Lander, F1
Beissert, S1
Günther, C1
Chastagner, M1
Shourik, J1
Jachiet, M1
Battistella, M1
Lefevre, G1
Gibier, JB1
Aubert, H1
Musquer, M1
Descamps, V1
Deschamps, L1
Chosidow, O1
Ortonne, N1
Groh, M1
Bernier, M1
Jullien, D1
Chasset, F1
Staumont-Salle, D1
Bouaziz, JD1
Kanitakis, J1
Villani, AP1
Bertello, M1
Rubegni, G1
Rubegni, P2
Tognetti, L2
Castro-Jiménez, A1
Gratacós-Gómez, AR1
Florido López, F1
Al Muqarrab, F1
Schwartz, RA2
Almohssen, AA1
Matsumura, N1
Yamamoto, T1
Ji, YZ1
Mei, XL1
Wei, FL1
Liu, SR1
Ji, YB1
Suarez-Valle, A1
Fernandez-Nieto, D1
Melian-Olivera, A1
Dominguez-Santas, M1
Diaz-Guimaraens, B1
Garcia Del Real, CM1
Jimenez-Cauhe, J1
Abadías-Granado, I1
Palma-Ruiz, AM1
Cerro, PA1
Morales-Callaghan, AM1
Gómez-Mateo, MC1
Gilaberte, Y1
Vargas-Mora, P1
Arceu, M1
Cortés, A1
Carreño, L1
Midorikawa, H1
Kiniwa, Y1
Minagawa, A1
Osawa, K1
Shirai, T1
Sano, T1
Nakamura, K1
Ashida, A1
Ueno, KI1
Takeichi, T2
Akiyama, M2
Okuyama, R1
Arakawa, H1
Tanese, K1
Tanaka, R1
Murakami, K1
Sujino, K1
Miyamoto, J1
Amagai, M1
Tanikawa, A1
Darjani, A1
Rafiei, R1
Mesbah, A1
Golmohammadi, R1
Rafiee, B1
Movaseghi, M1
Cinotti, E1
Fimiani, M1
Ishiguro, Y1
Muro, Y1
Murase, C1
Kono, M1
Adachi, R1
Takahashi, K1
Dick, J1
Kroehl, V1
Enk, AH1
Toberer, F1
Kucukunal, A1
Altunay, I1
Demirci, GT1
Sarikaya, S1
Sakiz, D1
Karataş Toğral, A1
Seçkin, D1
Fühler, M1
Ottmann, K1
Tronnier, M1
Samrao, A1
Chew, AL1
Price, V1
Yosipovitch, G1
Tan, A1
LoSicco, K1
Manabat, CG1
Kannagra, A1
Carroll, C1
Chan, YH1
Ng, P1
Jorizzo, J1
Marzano, AV1
Lazzari, R1
Polloni, I1
Boneschi, V1
Crosti, C1
Dereure, O1
Guilhou, JJ1
Beaver, ME1
Stasney, CR1
Rodriguez, M1
Terheyden, P1
Becker, JC1
Lurz, C1
Kahaly, GJ1
Bröcker, EB1
de Winter, S1
van Buchem, MA1
Vermeer, MH1
Ashurst, PJ1
Balogh, E1
Nagy-Vezekényi, K1
Fórizs, E1
de Boer, EM1
Nieboer, C1
Pluis, AH1
Verburgh-van der Zwan, N1
van Dijk, E1
Cash, JM1
Tyree, J1
Recht, M1
Keczkes, K1
Jadhav, P1
Ochonisky, S1
Bonvalet, D1
Caron, C1
Kornhauser, R1
Vignon-Pennamen, MD1
Dubertret, L1
Rekant, SI1
Becker, LE1
Lester, RS1
Burnham, TK1
Fine, G1
Murray, K1
Knox, JM1
Dodge, BG1
Freeman, RG1

Reviews

3 reviews available for hydroxychloroquine and Erythema

ArticleYear
Treatment of Eosinophilic Annular Erythema: Retrospective multicenter study and literature review.
    Annales de dermatologie et de venereologie, 2022, Volume: 149, Issue:2

    Topics: Adrenal Cortex Hormones; Dapsone; Eosinophilia; Erythema; Humans; Hydroxychloroquine; Multicenter St

2022
Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review.
    Acta dermatovenerologica Croatica : ADC, 2022, Volume: 30, Issue:4

    Topics: Acute Generalized Exanthematous Pustulosis; COVID-19; COVID-19 Drug Treatment; Erythema; Humans; Hyd

2022
A secondary discoid lupus erythematosus induced by scald of edible oil: An illustration of Koebner phenomenon.
    Journal of cosmetic dermatology, 2020, Volume: 19, Issue:7

    Topics: Burns; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Middle Aged; Tacr

2020

Other Studies

32 other studies available for hydroxychloroquine and Erythema

ArticleYear
Annular erythematous plaques as manifestation of vasculitis in pediatric Sjögren's syndrome.
    Rheumatology (Oxford, England), 2022, 02-02, Volume: 61, Issue:2

    Topics: Antirheumatic Agents; Azathioprine; Child; Erythema; Face; Female; Fingers; Humans; Hydroxychloroqui

2022
Authors' reply to: 'Generalized pustular figurate erythema first report in two COVID-19 patients on hydroxychloroquine'.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2023, Volume: 37, Issue:2

    Topics: COVID-19; COVID-19 Drug Treatment; Erythema; Humans; Hydroxychloroquine

2023
[Multiform exudative erythema caused by hydroxychloroquine, diagnosed by epicutaneous tests: A case report].
    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 2023, Feb-01, Volume: 69, Issue:3

    Topics: COVID-19; COVID-19 Drug Treatment; Erythema; Female; Humans; Hydroxychloroquine; Hypersensitivity, D

2023
CD123 and MxA expression in a case of annular erythema associated with primary Sjögren's syndrome successfully treated with hydroxychloroquine.
    The Australasian journal of dermatology, 2023, Volume: 64, Issue:3

    Topics: Erythema; Humans; Hydroxychloroquine; Interleukin-3 Receptor alpha Subunit; Sjogren's Syndrome

2023
Comment on "Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine": Report of a COVID-19 patient with particular findings.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: COVID-19; Erythema; Humans; Hydroxychloroquine; Pharmaceutical Preparations; SARS-CoV-2

2020
Generalized pustular figurate erythema first report in two COVID-19 patients on hydroxychloroquine.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2021, Volume: 35, Issue:1

    Topics: Antimalarials; COVID-19 Drug Treatment; Drug Eruptions; Erythema; Female; Humans; Hydroxychloroquine

2021
Multiple annular plaques in an adult woman.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020, Volume: 18, Issue:9

    Topics: Cetirizine; Dapsone; Eosinophilia; Erythema; Female; Humans; Hydroxychloroquine; Middle Aged; Predni

2020
Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation.
    The Journal of dermatology, 2021, Volume: 48, Issue:9

    Topics: Erythema; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Mutation; Psoriasis

2021
Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome.
    The Journal of dermatology, 2021, Volume: 48, Issue:10

    Topics: Erythema; Humans; Hydroxychloroquine; Retrospective Studies; Sjogren's Syndrome; Skin Diseases, Gene

2021
Discoid Lupus Erythematosus Presenting as Upper Eyelid Edema and Erythema.
    Acta medica Iranica, 2017, Volume: 55, Issue:7

    Topics: Adult; Alopecia; Edema; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid;

2017
Palpable migratory arciform erythema: hydroxychloroquine as a possible therapeutic option.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2019, Volume: 154, Issue:3

    Topics: Dermatologic Agents; Erythema; Female; Humans; Hydroxychloroquine; Middle Aged; Skin Diseases; Treat

2019
Drug-induced acute eosinophilic pneumonia due to hydroxychloroquine in a chilblain lupus patient.
    The Journal of dermatology, 2019, Volume: 46, Issue:10

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Betamethasone; Chilblains; Drug Therapy, Comb

2019
Reticular erythematous mucinosis in a young woman: Complete remission following oral hydroxychloroquine.
    The Australasian journal of dermatology, 2019, Volume: 60, Issue:4

    Topics: Administration, Oral; Biopsy, Needle; Erythema; Female; Follow-Up Studies; Humans; Hydroxychloroquin

2019
Reticular erythematous mucinosis on the midline of the back.
    Cutis, 2014, Volume: 93, Issue:6

    Topics: Antimalarials; Back; Dermatologic Agents; Erythema; Humans; Hydroxychloroquine; Male; Middle Aged; M

2014
Eosinophilic annular erythema: A late but complete response to hydroxychloroquine.
    The Australasian journal of dermatology, 2017, Volume: 58, Issue:3

    Topics: Aged; Antimalarials; Eosinophilia; Erythema; Female; Humans; Hydroxychloroquine; Skin Diseases, Gene

2017
Reticular erythematous mucinosis--(REM syndrome) in twins.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2009, Volume: 7, Issue:11

    Topics: Adult; Breast Diseases; Erythema; Female; Humans; Hydroxychloroquine; Mucinoses; Treatment Outcome;

2009
Frontal fibrosing alopecia: a clinical review of 36 patients.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Anti-Bacterial Agents; Cohort Studies; Dermatologic Agents

2010
A comparative study of clinical characteristics, work-up, treatment, and association to malignancy in dermatomyositis between two tertiary skin centers in the USA and Singapore.
    International journal of dermatology, 2013, Volume: 52, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Asian People; Bone Den

2013
Rosacea-like cutaneous lupus erythematosus: an atypical presentation responding to antimalarials.
    Acta dermato-venereologica, 2013, Volume: 93, Issue:1

    Topics: Adult; Aged; Antimalarials; Diagnosis, Differential; Erythema; Female; Humans; Hydroxychloroquine; L

2013
[Eosinophilic-like erythema: a clinical subset of Wells' eosinophilic cellulitis responding to antimalarial drugs?].
    Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:5 Pt 1

    Topics: Adult; Antimalarials; Cellulitis; Eosinophilia; Erythema; Female; Humans; Hydroxychloroquine; Syndro

2002
Rheumatoid nodules and reflux disease.
    Ear, nose, & throat journal, 2004, Volume: 83, Issue:5

    Topics: Adult; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Erythema; Female; Gastroesophageal

2004
Treatment of scleromyxoedema with hydroxychloroquine.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2003, Volume: 1, Issue:1

    Topics: Adult; Dermatologic Agents; Erythema; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Myxedem

2003
Annular erythema of Sjögren's syndrome.
    Lancet (London, England), 2006, May-13, Volume: 367, Issue:9522

    Topics: Adult; Dermatologic Agents; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Syste

2006
Erythema annulare centrifugum due to hydroxychloroquine sulfate and chloroquine sulfate.
    Archives of dermatology, 1967, Volume: 95, Issue:1

    Topics: Adult; Aged; Antimalarials; Chloroquine; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythem

1967
REM syndrome: an immediate therapeutic response to hydroxychloroquine sulphate.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:2

    Topics: Adult; Erythema; Female; Glycosaminoglycans; Humans; Hydroxychloroquine; Mucins; Skin; Skin Diseases

1980
[Reticular erythematous mucinosis].
    Nederlands tijdschrift voor geneeskunde, 1983, Apr-16, Volume: 127, Issue:16

    Topics: Adult; Erythema; Female; Humans; Hydroxychloroquine; Middle Aged; Mucins; Skin

1983
Severe multicentric reticulohistiocytosis: disease stabilization achieved with methotrexate and hydroxychloroquine.
    The Journal of rheumatology, 1997, Volume: 24, Issue:11

    Topics: Arthritis; Erythema; Female; Fingers; Histiocytosis; Humans; Hydroxychloroquine; Methotrexate; Middl

1997
REM syndrome (reticular erythematous mucinosis): report of a further case or variant of it.
    Archives of dermatology, 1977, Volume: 113, Issue:3

    Topics: Adult; Back; Erythema; Female; Gingival Diseases; Glycosaminoglycans; Histocytochemistry; Humans; Hy

1977
[Granulomatous cheilitis with cutaneous extension in Crohn disease. Regression with hydroxychloroquine].
    Annales de dermatologie et de venereologie, 1992, Volume: 119, Issue:11

    Topics: Adult; Anus Diseases; Crohn Disease; Erythema; Female; Humans; Hydroxychloroquine; Melkersson-Rosent

1992
Auto-immune annular erythema. A variant of lupus erythematosus?
    Archives of dermatology, 1973, Volume: 107, Issue:3

    Topics: Antibodies, Antinuclear; Autoimmune Diseases; Biopsy; Blood Protein Electrophoresis; Complement Fixa

1973
Immunologic concepts of light reactions in lupus erythematosus and polymorphous light eruptions. I. The mechanism of action of hydroxychloroquine.
    Archives of dermatology, 1967, Volume: 96, Issue:1

    Topics: Antibodies, Antinuclear; Autoantibodies; Chloroquine; DNA; Erythema; Humans; Hydralazine; Hydroxychl

1967
Erythema dyschromicum perstans.
    Archives of dermatology, 1968, Volume: 97, Issue:3

    Topics: Adolescent; Adult; Biopsy; Blood Cell Count; Blood Sedimentation; Child, Preschool; Chloroquine; Ery

1968