hydroxychloroquine has been researched along with Endocarditis, Bacterial in 26 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this case, cardiotoxicity is the consequence of the lysosomal dysfunction and the result of intracytoplasmic granular material inclusions." | 5.43 | [Early cardiotoxicity of Hydroxychloroquine]. ( Duhaut, P; Guillaumont, MP; Schmidt, J; Touati, G; Zerbib, Y, 2016) |
| " No previous studies have assessed abnormal weight gain as a putative side effect of long-term doxycycline treatment; thus, the objective of the present study was to characterize this phenomenon." | 5.40 | Abnormal weight gain and gut microbiota modifications are side effects of long-term doxycycline and hydroxychloroquine treatment. ( Angelakis, E; Armougom, F; Giorgi, R; Kankoe, S; Lagier, JC; Million, M; Raoult, D, 2014) |
| "The recommended treatment for Q fever endocarditis is a combination of doxycycline and hydroxychloroquine." | 2.71 | Correlation between serum doxycycline concentrations and serologic evolution in patients with Coxiella burnetii endocarditis. ( Mallet, MN; Raoult, D; Rolain, JM, 2003) |
| "A minority of patients who acquire acute Q fever will subsequently develop chronic Q fever endocarditis, which often manifests in valvular insufficiency." | 2.49 | Cardiac manifestations of Q fever infection: case series and a review of the literature. ( Farivar, RS; Gunn, TM; Raz, GM; Turek, JW, 2013) |
| "Coxiella burnetii, the agent of Q fever, is an obligate intracellular pathogen typically associated with exposure to livestock." | 2.48 | Q fever endocarditis: an unusual presentation. ( Espinosa, M; Griffin, AT; Nakamatsu, R, 2012) |
| "This study indicates that Q fever exists in our population." | 1.51 | Ten-year experience of Q fever endocarditis in a tertiary cardiac center in Saudi Arabia. ( Akhtar, MY; Albalawi, R; Albarrag, AM; Alnajashi, K; Alsherbeeni, N; Alsufyani, E; Alzahrani, A; Elzein, FE; Kaabia, N; Mehdi, S; Raoult, D, 2019) |
| "The epidemiology of Coxiella burnetii infection in the United States is not well characterized." | 1.48 | Coxiella burnetii Endocarditis and Meningitis, California, USA, 2017. ( Allan-Blitz, LT; Klausner, JD; Sakona, A; Wallace, WD, 2018) |
| "In this case, cardiotoxicity is the consequence of the lysosomal dysfunction and the result of intracytoplasmic granular material inclusions." | 1.43 | [Early cardiotoxicity of Hydroxychloroquine]. ( Duhaut, P; Guillaumont, MP; Schmidt, J; Touati, G; Zerbib, Y, 2016) |
| " No previous studies have assessed abnormal weight gain as a putative side effect of long-term doxycycline treatment; thus, the objective of the present study was to characterize this phenomenon." | 1.40 | Abnormal weight gain and gut microbiota modifications are side effects of long-term doxycycline and hydroxychloroquine treatment. ( Angelakis, E; Armougom, F; Giorgi, R; Kankoe, S; Lagier, JC; Million, M; Raoult, D, 2014) |
| "Coxiella burnetii causes acute and chronic Q fever." | 1.31 | Risks factors and prevention of Q fever endocarditis. ( Carrieri, MP; Fenollar, F; Fournier, PE; Habib, G; Messana, T; Raoult, D, 2001) |
| "Q fever is a zoonosis caused by Coxiella burnetii." | 1.30 | Q fever tricuspid valve endocarditis. ( Brouqui, P; Casasoprana, A; Hvass, U; Lupoglazoff, JM; Magnier, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Stahl, JP | 1 |
| Varon, E | 1 |
| Bru, JP | 1 |
| Million, M | 2 |
| Brouqui, P | 3 |
| Raoult, D | 9 |
| Sabourin, E | 1 |
| Podglajen, I | 1 |
| Fournier, PE | 2 |
| Mainardi, JL | 1 |
| Renard, D | 1 |
| Richaud, C | 1 |
| Perrot, L | 1 |
| Charles, P | 1 |
| Regazzoni, V | 1 |
| Loffi, M | 1 |
| Garini, A | 1 |
| Danzi, GB | 1 |
| Allan-Blitz, LT | 1 |
| Sakona, A | 1 |
| Wallace, WD | 1 |
| Klausner, JD | 1 |
| Akamine, CM | 1 |
| Perez, ML | 1 |
| Lee, JH | 1 |
| Ing, MB | 1 |
| Elzein, FE | 1 |
| Alsherbeeni, N | 1 |
| Alnajashi, K | 1 |
| Alsufyani, E | 1 |
| Akhtar, MY | 1 |
| Albalawi, R | 1 |
| Albarrag, AM | 1 |
| Kaabia, N | 1 |
| Mehdi, S | 1 |
| Alzahrani, A | 1 |
| Gunn, TM | 1 |
| Raz, GM | 1 |
| Turek, JW | 1 |
| Farivar, RS | 1 |
| Montejo, M | 1 |
| Goikoetxea, J | 1 |
| Mularoni, A | 1 |
| Blanco, MJ | 1 |
| Gaafar, A | 1 |
| Boado, MV | 1 |
| Marín, M | 1 |
| Aramendi, JI | 1 |
| Angelakis, E | 1 |
| Kankoe, S | 1 |
| Lagier, JC | 3 |
| Armougom, F | 1 |
| Giorgi, R | 1 |
| Emonet, S | 1 |
| Wuillemin, T | 1 |
| Harbarth, S | 1 |
| Wassilew, N | 1 |
| Cikirikcioglu, M | 1 |
| Schrenzel, J | 1 |
| van Delden, C | 1 |
| Zerbib, Y | 1 |
| Guillaumont, MP | 1 |
| Touati, G | 1 |
| Duhaut, P | 1 |
| Schmidt, J | 1 |
| Gruber, JR | 1 |
| Sarro, R | 1 |
| Delaloye, J | 1 |
| Surmely, JF | 1 |
| Siniscalchi, G | 1 |
| Tozzi, P | 1 |
| Jaques, C | 1 |
| Jaton, K | 1 |
| Delabays, A | 1 |
| Greub, G | 1 |
| Rutz, T | 1 |
| Cammilleri, S | 1 |
| Ansemant, T | 1 |
| Celard, M | 1 |
| Tavernier, C | 1 |
| Maillefert, JF | 1 |
| Delahaye, F | 1 |
| Ornetti, P | 1 |
| Zekanović, D | 1 |
| Morović, M | 1 |
| Borcilo, MN | 1 |
| Rode, OD | 1 |
| Costiniuk, CT | 1 |
| Wang, B | 1 |
| Johnstone, D | 1 |
| Jessamine, P | 1 |
| Toye, B | 1 |
| Veinot, JP | 1 |
| Desjardins, M | 1 |
| Griffin, AT | 1 |
| Espinosa, M | 1 |
| Nakamatsu, R | 1 |
| Rolain, JM | 2 |
| Mallet, MN | 2 |
| Boulos, A | 1 |
| Healy, B | 1 |
| Llewelyn, M | 1 |
| Westmoreland, D | 1 |
| Lloyd, G | 1 |
| Brown, N | 1 |
| Fradi, I | 1 |
| Drissa, MA | 1 |
| Cheour, M | 1 |
| Drissa, H | 1 |
| Lupoglazoff, JM | 1 |
| Magnier, S | 1 |
| Hvass, U | 1 |
| Casasoprana, A | 1 |
| Houpikian, P | 1 |
| Tissot Dupont, H | 1 |
| Riss, JM | 1 |
| Arditi-Djiane, J | 1 |
| Fenollar, F | 1 |
| Carrieri, MP | 1 |
| Habib, G | 1 |
| Messana, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial Evaluating Safety and Efficacy of Hydroxychloroquine and Nitazoxanide Combination as Adjuvant Therapy in Covid-19 Newly Diagnosed Egyptian Patients: A Tanta University Hope[NCT04361318] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2020-05-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydroxychloroquine and Endocarditis, Bacterial
| Article | Year |
|---|---|
Cardiac manifestations of Q fever infection: case series and a review of the literature.
Topics: Adult; Anti-Bacterial Agents; Antirheumatic Agents; Aortic Coarctation; Aortic Valve Insufficiency; | 2013 |
First case of Q fever endocarditis in Croatia and a short review.
Topics: Aged; Ciprofloxacin; Doxycycline; Echocardiography; Endocarditis, Bacterial; Humans; Hydroxychloroqu | 2010 |
Q fever endocarditis: an unusual presentation.
Topics: Anti-Bacterial Agents; Aortic Valve; Coxiella burnetii; Doxycycline; Drug Therapy, Combination; Endo | 2012 |
1 trial available for hydroxychloroquine and Endocarditis, Bacterial
| Article | Year |
|---|---|
Correlation between serum doxycycline concentrations and serologic evolution in patients with Coxiella burnetii endocarditis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibodies, Bacterial; Coxiella burnetii; Dox | 2003 |
22 other studies available for hydroxychloroquine and Endocarditis, Bacterial
| Article | Year |
|---|---|
Treatment of Coxiella burnetii endocarditis with hydroxychloroquine. Is it evidence-based?
Topics: Coxiella burnetii; Endocarditis; Endocarditis, Bacterial; Humans; Hydroxychloroquine; Q Fever | 2022 |
Re: Treatment of Coxiella burnetii endocarditis with hydroxychloroquine by Stahl et al.
Topics: Coxiella burnetii; Endocarditis; Endocarditis, Bacterial; Humans; Hydroxychloroquine; Q Fever | 2022 |
Clinical and biological diagnosis and follow-up of patients treated for endovascular infections due to Coxiellaburnetii.
Topics: Anti-Bacterial Agents; Doxycycline; Endocarditis; Endocarditis, Bacterial; Follow-Up Studies; Humans | 2023 |
[Hydroxychloroquine cured pneumonia].
Topics: Aged; Coxiella burnetii; Doxycycline; Endocarditis, Bacterial; Female; Humans; Hydroxychloroquine; L | 2020 |
Glucocorticoid-Induced Bacterial Endocarditis in COVID-19 Pneumonia - Something to Be Concerned About?
Topics: Aged; Anti-Bacterial Agents; Betacoronavirus; Coinfection; Coronavirus Infections; COVID-19; COVID-1 | 2020 |
Coxiella burnetii Endocarditis and Meningitis, California, USA, 2017.
Topics: Adult; Anti-Bacterial Agents; Antibodies, Bacterial; California; Coxiella burnetii; Doxycycline; End | 2018 |
Q Fever in Southern California: a Case Series of 20 Patients from a VA Medical Center.
Topics: Adult; Aged; Anti-Bacterial Agents; California; Chronic Disease; Doxycycline; Endocarditis, Bacteria | 2019 |
Ten-year experience of Q fever endocarditis in a tertiary cardiac center in Saudi Arabia.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Doxycycline; Endocarditis, Bacterial; Female; Heart | 2019 |
[Tropheryma wipplei endocarditis: a report of 3 cases].
Topics: Actinomycetales Infections; Anti-Bacterial Agents; Anticoagulants; Doxycycline; Drug Therapy, Combin | 2013 |
Abnormal weight gain and gut microbiota modifications are side effects of long-term doxycycline and hydroxychloroquine treatment.
Topics: Adult; Aged; Anti-Infective Agents; Body Mass Index; Body Weight; Doxycycline; Endocarditis, Bacteri | 2014 |
Relapse of Tropheryma whipplei endocarditis treated by trimethoprim/sulfamethoxazole, cured by hydroxychloroquine plus doxycycline.
Topics: Anti-Bacterial Agents; Aortic Valve; Ceftriaxone; Doxycycline; Drug Therapy, Combination; Endocardit | 2015 |
[Early cardiotoxicity of Hydroxychloroquine].
Topics: Aged; Antimalarials; Cardiotoxicity; Endocarditis, Bacterial; Female; Humans; Hydroxychloroquine; Wh | 2016 |
Tropheryma whipplei bivalvular endocarditis and polyarthralgia: a case report.
Topics: Aged; Anti-Bacterial Agents; Aortic Valve; Arthralgia; Doxycycline; Echocardiography; Endocarditis, | 2015 |
Classic Whipple's disease diagnosed by (18)F-fluorodeoxyglucose PET.
Topics: Doxycycline; Endocarditis, Bacterial; Fluorodeoxyglucose F18; Humans; Hydroxychloroquine; Male; Midd | 2016 |
Whipple's disease endocarditis following anti-TNF therapy for atypical rheumatoid arthritis.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Diagnosis, Differential; | 2010 |
Coxiella burnetii culture-negative endocarditis diagnosed by 16S rRNA sequencing of heart valve tissue.
Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Coxiella burnetii; Doxycycline; Drug Therapy, Co | 2011 |
Correlation between ratio of serum doxycycline concentration to MIC and rapid decline of antibody levels during treatment of Q fever endocarditis.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibodies, Bacterial; Coxiella burnetii; Doxycycline; Endocardi | 2005 |
The value of follow-up after acute Q fever infection.
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Chronic Disease; Complement Fixation Tests; Coxiella b | 2006 |
[Q fever endocarditis: a case report].
Topics: Adult; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Stenosis; Doxycycline; Drug Therapy, Combin | 2006 |
Q fever tricuspid valve endocarditis.
Topics: Anti-Bacterial Agents; Child; Doxycycline; Drug Therapy, Combination; Endocarditis, Bacterial; Femal | 1997 |
Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Endocar | 1999 |
Risks factors and prevention of Q fever endocarditis.
Topics: Aged; Anti-Infective Agents; Doxycycline; Endocarditis, Bacterial; Female; Heart Valve Diseases; Hum | 2001 |