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hydroxychloroquine and Elevated Cholesterol

hydroxychloroquine has been researched along with Elevated Cholesterol in 6 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether hydroxychloroquine treatment is associated with major adverse cardiovascular events (MACE) (myocardial infarction, ischemic stroke, or cardiovascular-associated death) in patients with cutaneous LE (CLE) or systemic LE (SLE)."4.02Use of hydroxychloroquine and risk of major adverse cardiovascular events in patients with lupus erythematosus: A Danish nationwide cohort study. ( Dreyer, L; Egeberg, A; Gislason, G; Haugaard, JH; Kofoed, K; Ottosen, MB, 2021)
"(1) Hydroxychloroquine has a possible anti-thrombotic action."2.38The relevance of antimalarial therapy with regard to thrombosis, hypercholesterolemia and cytokines in SLE. ( Linker-Israeli, M; Metzger, AL; Stecher, VJ; Wallace, DJ, 1993)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Haugaard, JH1
Dreyer, L1
Ottosen, MB1
Gislason, G1
Kofoed, K1
Egeberg, A1
Houssen, ME1
El-Mahdy, RH1
Shahin, DA1
Inhoff, O1
Peitsch, WK1
Paredes, BE1
Goerdt, S1
Goebeler, M1
McLaurin, EY1
Holliday, SL1
Williams, P1
Brey, RL1
Wallace, DJ1
Linker-Israeli, M1
Metzger, AL1
Stecher, VJ1
Rahman, P1
Gladman, DD1
Urowitz, MB1
Yuen, K1
Hallett, D1
Bruce, IN1

Reviews

1 review available for hydroxychloroquine and Elevated Cholesterol

ArticleYear
The relevance of antimalarial therapy with regard to thrombosis, hypercholesterolemia and cytokines in SLE.
    Lupus, 1993, Volume: 2 Suppl 1

    Topics: Animals; Antimalarials; CD8 Antigens; Humans; Hydroxychloroquine; Hypercholesterolemia; Interleukin-

1993

Other Studies

5 other studies available for hydroxychloroquine and Elevated Cholesterol

ArticleYear
Use of hydroxychloroquine and risk of major adverse cardiovascular events in patients with lupus erythematosus: A Danish nationwide cohort study.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:4

    Topics: Adult; Brain Ischemia; Cardiovascular Diseases; Cohort Studies; Comorbidity; Confounding Factors, Ep

2021
Serum soluble toll-like receptor 2: a novel biomarker for systemic lupus erythematosus disease activity and lupus-related cardiovascular dysfunction.
    International journal of rheumatic diseases, 2016, Volume: 19, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Biomarkers; Case-Control Studies; Creatinine;

2016
Simvastatin-induced amyopathic dermatomyositis.
    The British journal of dermatology, 2009, Volume: 161, Issue:1

    Topics: Aged; Biopsy; Dermatomyositis; Female; Humans; Hydroxychloroquine; Hydroxymethylglutaryl-CoA Reducta

2009
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant

2005
The cholesterol lowering effect of antimalarial drugs is enhanced in patients with lupus taking corticosteroid drugs.
    The Journal of rheumatology, 1999, Volume: 26, Issue:2

    Topics: Antimalarials; Antirheumatic Agents; Chloroquine; Cholesterol; Dose-Response Relationship, Drug; Dru

1999