Page last updated: 2024-10-28

hydroxychloroquine and Edema-Proteinuria-Hypertension Gestosis

hydroxychloroquine has been researched along with Edema-Proteinuria-Hypertension Gestosis in 31 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"Hydroxychloroquine (HCQ) is the primary medication in the treatment of pregnancy with systemic lupus erythematosus (SLE) for its efficacy and safety."9.12Effect of hydroxychloroquine on preeclampsia in lupus pregnancies: a propensity score-matched analysis and meta-analysis. ( Liu, Y; Wei, Y; Yang, H; Zhang, Y, 2021)
" Hydroxychloroquine (HCQ) has demonstrated beneficial effects on disease flares, pregnancy outcomes and cardiovascular impairment in systemic erythaematosus lupus (SLE) through its immunomodulatory, vasculoprotective and antithrombotic properties."9.05Hydroxychloroquine may be beneficial in preeclampsia and recurrent miscarriage. ( Alavi, Z; de Moreuil, C; Pasquier, E, 2020)
"This study was conducted to analyse the medication indications of hydroxychloroquine (HCQ) and to explore the clinical characteristics and perinatal outcomes of pregnancy in women with autoimmune abnormalities."8.31The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities. ( Liu, Y; Ma, Y; Wang, Y; Ye, S; Zhao, J; Zhao, X, 2023)
"We conclude that hydroxychloroquine alleviated hypertension, proteinuria, and normalized soluble fms-like kinase-1 and endothelin-1 levels in our preeclampsia model and that these changes may involve the restoration of endothelial dysfunction; thus, hydroxychloroquine could potentially be used for preventing preeclampsia, even in the absence of lupus."8.12Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model. ( Byun, N; Cho, GJ; Choi, M; Choi, SJ; Hwang, JR; Kim, JS; Oh, SY; Roh, CR; Seok, YS; Sung, JH, 2022)
" Multiple logistic analysis adjusting for body mass index (BMI), lupus nephritis, serum uric acid, and estimated glomerular filtration rate revealed HCQ treatment was associated with exceedingly lower risk of preeclampsia in SLE pregnancy (odds ratio (OR) 0."7.91Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia. ( Cha, HS; Chae, J; Choi, SJ; Kim, YM; Oh, S; Roh, CR; Seo, MR, 2019)
" Lupus flares were predicted by HCQ discontinuation, a history of lupus nephritis, high pre-pregnancy serum uric acid and low C4 levels."7.81Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus. ( Ju, JH; Ko, HS; Koh, JH; Kwok, SK; Park, SH, 2015)
"Preeclampsia, gestational hypertension, and prematurity were significantly lower in the HCQ+ group than in the HCQ- group (OR 0."6.72Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis. ( Duan, J; Gao, J; Guo, Q; Ma, D; Wen, X; Xu, K; Zhang, G; Zhang, L, 2021)
"HCQ exposure and preeclampsia, along with other clinical data, were extracted from chart review."5.56Does Hydroxychloroquine Protect against Preeclampsia and Preterm Delivery in Systemic Lupus Erythematosus Pregnancies? ( Do, SC; Druzin, ML; Rizk, NM; Simard, JF, 2020)
"Hydroxychloroquine (HCQ) is the primary medication in the treatment of pregnancy with systemic lupus erythematosus (SLE) for its efficacy and safety."5.12Effect of hydroxychloroquine on preeclampsia in lupus pregnancies: a propensity score-matched analysis and meta-analysis. ( Liu, Y; Wei, Y; Yang, H; Zhang, Y, 2021)
" Hydroxychloroquine (HCQ) has demonstrated beneficial effects on disease flares, pregnancy outcomes and cardiovascular impairment in systemic erythaematosus lupus (SLE) through its immunomodulatory, vasculoprotective and antithrombotic properties."5.05Hydroxychloroquine may be beneficial in preeclampsia and recurrent miscarriage. ( Alavi, Z; de Moreuil, C; Pasquier, E, 2020)
" Current treatment of patients with antiphospholipid syndrome (APS) during pregnancy with heparin and aspirin can act by preventing clot formation and improving live birth rates, but other obstetric morbidities remain high, especially in patients with a history of thrombotic events."4.90Pregnancy morbidity in antiphospholipid syndrome: what is the impact of treatment? ( de Jesús, GR; de Jesús, NR; Levy, RA; Rodrigues, G, 2014)
"This study was conducted to analyse the medication indications of hydroxychloroquine (HCQ) and to explore the clinical characteristics and perinatal outcomes of pregnancy in women with autoimmune abnormalities."4.31The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities. ( Liu, Y; Ma, Y; Wang, Y; Ye, S; Zhao, J; Zhao, X, 2023)
"We conclude that hydroxychloroquine alleviated hypertension, proteinuria, and normalized soluble fms-like kinase-1 and endothelin-1 levels in our preeclampsia model and that these changes may involve the restoration of endothelial dysfunction; thus, hydroxychloroquine could potentially be used for preventing preeclampsia, even in the absence of lupus."4.12Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model. ( Byun, N; Cho, GJ; Choi, M; Choi, SJ; Hwang, JR; Kim, JS; Oh, SY; Roh, CR; Seok, YS; Sung, JH, 2022)
" Hydroxychloroquine is an immune modulating drug that is considered safe in pregnancy."4.12Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro. ( Beard, S; Binder, N; Brownfoot, FC; Hannan, N; Harper, A; Kadife, E, 2022)
" Several management options for prolongation of pregnancy such as plasma exchange, pravastatin, LMHW, hydroxychloroquine/HCQ, or TNF-alpha blocker should be discussed with the patients."3.96Preeclampsia before fetal viability in women with primary antiphospholipid syndrome- materno-fetal outcomes in a series of 7 cases. ( Cervar-Zivkovic, M; Mayer-Pickel, K; Moertl, M; Schöll, W; Stern, C, 2020)
" Multiple logistic analysis adjusting for body mass index (BMI), lupus nephritis, serum uric acid, and estimated glomerular filtration rate revealed HCQ treatment was associated with exceedingly lower risk of preeclampsia in SLE pregnancy (odds ratio (OR) 0."3.91Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia. ( Cha, HS; Chae, J; Choi, SJ; Kim, YM; Oh, S; Roh, CR; Seo, MR, 2019)
" Lupus flares were predicted by HCQ discontinuation, a history of lupus nephritis, high pre-pregnancy serum uric acid and low C4 levels."3.81Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus. ( Ju, JH; Ko, HS; Koh, JH; Kwok, SK; Park, SH, 2015)
"Preeclampsia, gestational hypertension, and prematurity were significantly lower in the HCQ+ group than in the HCQ- group (OR 0."2.72Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis. ( Duan, J; Gao, J; Guo, Q; Ma, D; Wen, X; Xu, K; Zhang, G; Zhang, L, 2021)
"Adequate pregnancy care of women with systemic lupus erythematosus (SLE) rests on three pillars: a coordinated medical-obstetrical care, an agreed and well-defined management protocol and a good neonatal unit."2.47Lupus and pregnancy: integrating clues from the bench and bedside. ( Khamashta, MA; Ruiz-Irastorza, G, 2011)
"COVID-19 and preeclampsia (preE) share the ANG-II mediated endothelial dysfunction, resulting from a significant dysregulation of RAS and an imbalanced proportion of anti-angiogenic and pro-angiogenic soluble plasmatic factors."1.72Imbalanced Angiogenesis in Pregnancies Complicated by SARS-CoV-2 Infection. ( Acampora, E; Arienti, F; Carrer, A; Casati, M; Gambacorti-Passerini, C; Giardini, V; Ornaghi, S; Vasarri, MV; Vergani, P, 2022)
"HCQ exposure and preeclampsia, along with other clinical data, were extracted from chart review."1.56Does Hydroxychloroquine Protect against Preeclampsia and Preterm Delivery in Systemic Lupus Erythematosus Pregnancies? ( Do, SC; Druzin, ML; Rizk, NM; Simard, JF, 2020)
"Preterm birth was defined as a birth <37 weeks gestation."1.48Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus. ( Clowse, MEB; Eudy, AM; Haroun, T; James, AH; Jayasundara, M; Neil, L, 2018)
"Hydroxychloroquine is an anti-malarial drug which, due to its anti-inflammatory and immunomodulatory effects, is widely used for the treatment of autoimmune diseases."1.43The effects of hydroxychloroquine on endothelial dysfunction. ( Gurusinghe, S; Lim, R; Mockler, JC; Murthi, P; Rahman, R; Singh, H; Wallace, EM, 2016)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.23)29.6817
2010's11 (35.48)24.3611
2020's19 (61.29)2.80

Authors

AuthorsStudies
Giardini, V1
Ornaghi, S1
Gambacorti-Passerini, C1
Casati, M1
Carrer, A1
Acampora, E1
Vasarri, MV1
Arienti, F1
Vergani, P1
Choi, M1
Hwang, JR1
Sung, JH1
Byun, N1
Seok, YS1
Cho, GJ1
Choi, SJ2
Kim, JS1
Oh, SY1
Roh, CR2
Kadife, E3
Hannan, N3
Harper, A3
Binder, N3
Beard, S3
Brownfoot, FC3
Phillips, J3
Nathan, E3
Graham, D3
Ye, S2
Zhao, X2
Liu, Y4
Ma, Y2
Wang, Y2
Zhao, J2
Wei, Y2
Zhang, Y2
Yang, H2
León-Martínez, D1
Lynn, T1
Abrahams, VM1
de Moreuil, C1
Alavi, Z1
Pasquier, E1
Petri, M2
Do, SC1
Rizk, NM1
Druzin, ML1
Simard, JF1
Mayer-Pickel, K1
Stern, C1
Cervar-Zivkovic, M1
Schöll, W1
Moertl, M1
Rahman, RA1
Murthi, P3
Singh, H2
Gurungsinghe, S1
Leaw, B1
Mockler, JC2
Lim, R2
Wallace, EM3
Juusela, A1
Nazir, M1
Gimovsky, M1
Janardana, R1
Haridas, V1
Priya, V1
Bhat, V1
Singh, Y1
Rao, VK1
Jois, R1
Srikantiah, C1
Pinto, B1
Shobha, V1
Latino, JO1
Udry, S1
Aranda, F1
Wingeyer, SP1
Romero, DSF1
Belizna, C1
Larrañaga, G1
Ortiz Molina, E1
Hernandez Pailos, R1
Pola Guillen, M1
Pascual Pedreno, A1
Rodriguez Rodriguez, E1
Hernandez Martinez, A1
Duan, J1
Ma, D1
Wen, X1
Guo, Q1
Gao, J1
Zhang, G1
Xu, K1
Zhang, L1
Chavatza, K1
Kostopoulou, M1
Nikolopoulos, D1
Gioti, O1
Togia, K1
Andreoli, L1
Aringer, M1
Boletis, J1
Doria, A1
Houssiau, FA1
Jayne, D1
Mosca, M1
Svenungsson, E1
Tincani, A1
Bertsias, G1
Fanouriakis, A1
Boumpas, DT1
Lateef, A1
Eudy, AM1
Jayasundara, M1
Haroun, T1
Neil, L1
James, AH1
Clowse, MEB1
Seo, MR1
Chae, J1
Kim, YM1
Cha, HS1
Oh, S1
de Jesús, GR1
Rodrigues, G1
de Jesús, NR1
Levy, RA1
Koh, JH1
Ko, HS1
Kwok, SK1
Ju, JH1
Park, SH1
Tedeschi, SK1
Guan, H1
Fine, A1
Costenbader, KH1
Bermas, B1
Schreiber, K1
Hunt, BJ1
Rahman, R1
Gurusinghe, S1
Abd Rahman, R1
DeKoninck, P1
Teh, CL1
Wong, JS1
Ngeh, NK1
Loh, WL1
Ruiz-Irastorza, G1
Khamashta, MA1
Golding, A1
Haque, UJ1
Giles, JT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Three-arm, Multicenter, Open-label Randomized Controlled Trial of Hydroxychloroquine and Low-dose Prednisone on Recurrent Spontaneous Abortion With Undifferentiated Connective Tissue Diseases: Protocol for the Immunosuppressant Regimens for Living FEtus[NCT03671174]420 participants (Anticipated)Interventional2019-08-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for hydroxychloroquine and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Hydroxychloroquine significantly decreases the risk of preeclampsia in pregnant women with autoimmune disorders: a systematic review and meta-analysis.
    Clinical rheumatology, 2023, Volume: 42, Issue:5

    Topics: Autoimmune Diseases; Case-Control Studies; Female; Humans; Hydroxychloroquine; Hypertension, Pregnan

2023
Hydroxychloroquine may be beneficial in preeclampsia and recurrent miscarriage.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:1

    Topics: Abortion, Habitual; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Infant, Newborn; Lupus

2020
Pregnancy and Systemic Lupus Erythematosus.
    Best practice & research. Clinical obstetrics & gynaecology, 2020, Volume: 64

    Topics: Adult; Antimalarials; Antiphospholipid Syndrome; Female; Humans; Hydroxychloroquine; Infant, Newborn

2020
Effect of hydroxychloroquine on preeclampsia in lupus pregnancies: a propensity score-matched analysis and meta-analysis.
    Archives of gynecology and obstetrics, 2021, Volume: 303, Issue:2

    Topics: Adult; Antirheumatic Agents; Female; Gestational Age; Humans; Hydroxychloroquine; Lupus Erythematosu

2021
Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis.
    Lupus, 2021, Volume: 30, Issue:7

    Topics: Abortion, Spontaneous; Antirheumatic Agents; Case-Control Studies; Diabetes, Gestational; Female; HE

2021
Systemic Lupus Erythematosus and Pregnancy.
    Rheumatic diseases clinics of North America, 2017, Volume: 43, Issue:2

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Female; Fetal Growth Retardation; Humans; Hydroxychlo

2017
Pregnancy morbidity in antiphospholipid syndrome: what is the impact of treatment?
    Current rheumatology reports, 2014, Volume: 16, Issue:2

    Topics: Abortion, Habitual; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Female; Fetal Growth Retarda

2014
Pregnancy and Antiphospholipid Syndrome.
    Seminars in thrombosis and hemostasis, 2016, Volume: 42, Issue:7

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Female; Fetal Growth Retardation; Humans; H

2016
Treatment of preeclampsia with hydroxychloroquine: a review.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018, Volume: 31, Issue:4

    Topics: Adjuvants, Pharmaceutic; Antimalarials; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Sys

2018
Lupus and pregnancy: integrating clues from the bench and bedside.
    European journal of clinical investigation, 2011, Volume: 41, Issue:6

    Topics: Abortion, Spontaneous; Antibodies, Antiphospholipid; Anticoagulants; Aspirin; Azathioprine; Counseli

2011
Rheumatoid arthritis and reproduction.
    Rheumatic diseases clinics of North America, 2007, Volume: 33, Issue:2

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Hydroxychloroquine; Immunosuppre

2007

Other Studies

20 other studies available for hydroxychloroquine and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Imbalanced Angiogenesis in Pregnancies Complicated by SARS-CoV-2 Infection.
    Viruses, 2022, 10-07, Volume: 14, Issue:10

    Topics: Angiogenesis Inducing Agents; Biomarkers; COVID-19; Female; Fibrinolytic Agents; Humans; Hydroxychlo

2022
Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model.
    Journal of hypertension, 2022, 12-01, Volume: 40, Issue:12

    Topics: Animals; Blood Pressure; Endothelial Cells; Endothelin-1; Female; Hydroxychloroquine; Hypertension;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Biomarkers; Endoglin; Endothelial Cells; Female; Humans; Hydroxychloroquine; Inflammation; Placenta;

2022
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
Preeclampsia in women with lupus - Influence of aspirin and hydroxychloroquine on pregnancy outcome.
    Pregnancy hypertension, 2023, Volume: 31

    Topics: Aspirin; Australia; Female; Humans; Hydroxychloroquine; Pre-Eclampsia; Pregnancy; Pregnancy Complica

2023
The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities.
    Clinical rheumatology, 2023, Volume: 42, Issue:4

    Topics: Antiphospholipid Syndrome; Antirheumatic Agents; Autoantibodies; Female; Humans; Hydroxychloroquine;

2023
The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities.
    Clinical rheumatology, 2023, Volume: 42, Issue:4

    Topics: Antiphospholipid Syndrome; Antirheumatic Agents; Autoantibodies; Female; Humans; Hydroxychloroquine;

2023
The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities.
    Clinical rheumatology, 2023, Volume: 42, Issue:4

    Topics: Antiphospholipid Syndrome; Antirheumatic Agents; Autoantibodies; Female; Humans; Hydroxychloroquine;

2023
The use of hydroxychloroquine in pregnancy and its effect on perinatal outcomes in a population with autoimmune abnormalities.
    Clinical rheumatology, 2023, Volume: 42, Issue:4

    Topics: Antiphospholipid Syndrome; Antirheumatic Agents; Autoantibodies; Female; Humans; Hydroxychloroquine;

2023
Cell-free fetal DNA impairs trophoblast migration in a TLR9-dependent manner and can be reversed by hydroxychloroquine.
    Journal of reproductive immunology, 2023, Volume: 157

    Topics: Aspirin; Cell Line; Cell-Free Nucleic Acids; DNA; Female; Humans; Hydroxychloroquine; Placenta; Pre-

2023
Does Hydroxychloroquine Protect against Preeclampsia and Preterm Delivery in Systemic Lupus Erythematosus Pregnancies?
    American journal of perinatology, 2020, Volume: 37, Issue:9

    Topics: Adult; Antirheumatic Agents; California; Female; Humans; Hydroxychloroquine; Logistic Models; Lupus

2020
Preeclampsia before fetal viability in women with primary antiphospholipid syndrome- materno-fetal outcomes in a series of 7 cases.
    Journal of reproductive immunology, 2020, Volume: 138

    Topics: Adult; Antiphospholipid Syndrome; Female; Fetal Viability; Gestational Age; Heparin, Low-Molecular-W

2020
Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia.
    International journal of molecular sciences, 2020, Apr-03, Volume: 21, Issue:7

    Topics: Cell Hypoxia; Cell Survival; Dinoprost; Endoglin; Female; Human Umbilical Vein Endothelial Cells; Hu

2020
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi

2020
Maternal and fetal outcomes of lupus pregnancies: A collective effort by Karnataka Rheumatologists.
    Lupus, 2020, Volume: 29, Issue:11

    Topics: Abortion, Spontaneous; Adult; Female; Humans; Hydroxychloroquine; India; Infant, Newborn; Lupus Eryt

2020
Risk factors for early severe preeclampsia in obstetric antiphospholipid syndrome with conventional treatment. The impact of hydroxychloroquine.
    Lupus, 2020, Volume: 29, Issue:13

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Female; Heparin; Humans; Hy

2020
COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis.
    Ginekologia polska, 2020, Volume: 91, Issue:12

    Topics: Adult; Anosmia; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; C-Reactive Protein; Cesarea

2020
Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:9

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antirheumatic Agents; Aspirin; Drug Tapering; Europe; Fema

2021
Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus.
    Lupus, 2018, Volume: 27, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cesarean Section; Female; Ges

2018
Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia.
    Lupus, 2019, Volume: 28, Issue:6

    Topics: Adult; Antirheumatic Agents; Female; Gestational Age; Humans; Hydroxychloroquine; Infant, Newborn; L

2019
Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus.
    Lupus, 2015, Volume: 24, Issue:2

    Topics: Adult; Antirheumatic Agents; Apgar Score; Female; Fetal Growth Retardation; Follow-Up Studies; Human

2015
Organ-specific systemic lupus erythematosus activity during pregnancy is associated with adverse pregnancy outcomes.
    Clinical rheumatology, 2016, Volume: 35, Issue:7

    Topics: Abortion, Spontaneous; Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Female; Humans; Hydroxy

2016
The effects of hydroxychloroquine on endothelial dysfunction.
    Pregnancy hypertension, 2016, Volume: 6, Issue:4

    Topics: Antimalarials; Endothelin-1; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydroxychloroqu

2016
Systemic lupus erythematosus pregnancies: the Sarawak experience and review of lupus pregnancies in Asia.
    Rheumatology international, 2011, Volume: 31, Issue:9

    Topics: Adult; Antirheumatic Agents; Asia; Cesarean Section; Cross-Sectional Studies; Disease Progression; F

2011