Page last updated: 2024-10-28

hydroxychloroquine and Dyslipidemia

hydroxychloroquine has been researched along with Dyslipidemia in 13 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of atorvastatin + hydroxychloroquine fixed-dose combination tablets in comparison with atorvastatin alone in treatment of dyslipidemia."9.20Efficacy and safety of fixed dose combination of atorvastatin and hydroxychloroquine: a randomized, double-blind comparison with atorvastatin alone among Indian patients with dyslipidemia. ( Agarwal, M; Agrawal, N; Chandurkar, N; Dhruv, U; Khyalappa, R; Legha, R; Mathur, SL; Pai, V; Pareek, A; Parmar, M; Pednekar, S; Salkar, HR; Saxena, S; Sriram, U; Thulaseedharan, NK, 2015)
"To evaluate the efficacy and safety of atorvastatin + hydroxychloroquine fixed-dose combination tablets in comparison with atorvastatin alone in treatment of dyslipidemia."5.20Efficacy and safety of fixed dose combination of atorvastatin and hydroxychloroquine: a randomized, double-blind comparison with atorvastatin alone among Indian patients with dyslipidemia. ( Agarwal, M; Agrawal, N; Chandurkar, N; Dhruv, U; Khyalappa, R; Legha, R; Mathur, SL; Pai, V; Pareek, A; Parmar, M; Pednekar, S; Salkar, HR; Saxena, S; Sriram, U; Thulaseedharan, NK, 2015)
" Secondary outcomes were duration of hospital stay, length of intensive care unit stay, 28-day mortality, effect of early or late administration of IFN on mortality, adverse effects, and complications during the hospitalization."2.94A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19. ( Abbasian, L; Davoudi-Monfared, E; Hajiabdolbaghi, M; Kazemzadeh, H; Khalili, H; Rahmani, H; Salehi, M; Yekaninejad, MS, 2020)
"Dyslipidemia is a common disorder in systemic lupus erythematosus (SLE) patients."2.61Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis. ( Chen, T; Cheng, GY; Jiang, YM; Liu, D; Shang, J; Tao, CY; Xiao, J; Yu, D; Zhao, ZZ, 2019)
"Hydroxychloroquine, a common treatment for SLE, can improve lipid profiles and should be considered for all patients with SLE."2.44Management of dyslipidemia in children and adolescents with systemic lupus erythematosus. ( Ardoin, SP; Sandborg, C; Schanberg, LE, 2007)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's9 (69.23)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Sharma, M1
Kumar, M1
Dutta, D1
Davoudi-Monfared, E1
Rahmani, H1
Khalili, H1
Hajiabdolbaghi, M1
Salehi, M1
Abbasian, L1
Kazemzadeh, H1
Yekaninejad, MS1
Santos, CS1
Morales, CM1
Álvarez, ED1
Castro, CÁ1
Robles, AL1
Sandoval, TP1
Grewal, SK1
Rubin, C1
Rosenbach, M1
Tao, CY1
Shang, J1
Chen, T1
Yu, D1
Jiang, YM1
Liu, D1
Cheng, GY1
Xiao, J1
Zhao, ZZ1
Migkos, MP1
Markatseli, TE1
Iliou, C1
Voulgari, PV1
Drosos, AA1
Pareek, A2
Chandurkar, N2
Thulaseedharan, NK1
Legha, R1
Agarwal, M1
Mathur, SL1
Salkar, HR1
Pednekar, S1
Pai, V1
Sriram, U1
Khyalappa, R1
Parmar, M1
Agrawal, N1
Dhruv, U1
Saxena, S1
Luthra, A2
Misra, A2
Mudur, G1
Jain, M1
Jani, RH1
Ardoin, SP1
Sandborg, C1
Schanberg, LE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Berberine on the Secretion of Incretin in Normal Man[NCT05947370]Early Phase 116 participants (Actual)Interventional2022-10-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydroxychloroquine and Dyslipidemia

ArticleYear
Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis.
    Medicine, 2019, Volume: 98, Issue:14

    Topics: Adult; Antimalarials; Chloroquine; Dyslipidemias; Female; Humans; Hydroxychloroquine; Lipids; Lupus

2019
Management of dyslipidemia in children and adolescents with systemic lupus erythematosus.
    Lupus, 2007, Volume: 16, Issue:8

    Topics: Adolescent; Bile Acids and Salts; Child; Complementary Therapies; Dyslipidemias; Humans; Hydroxychlo

2007

Trials

2 trials available for hydroxychloroquine and Dyslipidemia

ArticleYear
A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19.
    Antimicrobial agents and chemotherapy, 2020, 08-20, Volume: 64, Issue:9

    Topics: Adult; Aged; Antiviral Agents; Atazanavir Sulfate; Betacoronavirus; Cardiovascular Diseases; Comorbi

2020
Efficacy and safety of fixed dose combination of atorvastatin and hydroxychloroquine: a randomized, double-blind comparison with atorvastatin alone among Indian patients with dyslipidemia.
    Current medical research and opinion, 2015, Volume: 31, Issue:11

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Ch

2015

Other Studies

9 other studies available for hydroxychloroquine and Dyslipidemia

ArticleYear
Hydroxychloroquine in diabetes and dyslipidaemia: primum non nocere.
    Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:8

    Topics: Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Dyslipidemias; Enzyme Inhibitors; Human

2020
Determinants of COVID-19 disease severity in patients with underlying rheumatic disease.
    Clinical rheumatology, 2020, Volume: 39, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiv

2020
Antimalarial therapy for granuloma annulare: Results of a retrospective analysis.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Adult; Aged; Antimalarials; Dermatologic Agents; Diabetes Complications; Dyslipidemias; Female; Gluc

2017
Effect of hydroxychloroquine on the lipid profile of patients with Sjögren syndrome.
    The Journal of rheumatology, 2014, Volume: 41, Issue:5

    Topics: Aged; Antirheumatic Agents; Atherosclerosis; Dyslipidemias; Female; Humans; Hydroxychloroquine; Lipi

2014
The marketing of unproven drugs for diabetes and dyslipidaemia in India.
    The lancet. Diabetes & endocrinology, 2015, Volume: 3, Issue:10

    Topics: Berberine; Diabetes Mellitus, Type 2; Drug Approval; Drug Industry; Dyslipidemias; Humans; Hydroxych

2015
Indian endocrinologists start debate on diabetes drug.
    BMJ (Clinical research ed.), 2015, Sep-29, Volume: 351

    Topics: Berberine; Diabetes Mellitus, Type 2; Drug Approval; Drug Industry; Dyslipidemias; Humans; Hydroxych

2015
Drug approvals in India.
    The lancet. Diabetes & endocrinology, 2016, Volume: 4, Issue:1

    Topics: Berberine; Diabetes Mellitus, Type 2; Drug Approval; Drug Industry; Dyslipidemias; Humans; Hydroxych

2016
Drug approvals in India.
    The lancet. Diabetes & endocrinology, 2016, Volume: 4, Issue:1

    Topics: Berberine; Diabetes Mellitus, Type 2; Drug Approval; Drug Industry; Dyslipidemias; Humans; Hydroxych

2016
Drug approvals in India - Authors' reply.
    The lancet. Diabetes & endocrinology, 2016, Volume: 4, Issue:1

    Topics: Berberine; Diabetes Mellitus, Type 2; Drug Approval; Drug Industry; Dyslipidemias; Humans; Hydroxych

2016