Page last updated: 2024-10-28

hydroxychloroquine and Deficiency, Vitamin D

hydroxychloroquine has been researched along with Deficiency, Vitamin D in 6 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"Vitamin D deficiency was frequent in Chinese SLE patients and was associated with more active disease at baseline and over time, as well as a trend of more severe lupus flares."1.48Serum 25-hydroxyvitamin D3 levels and flares of systemic lupus erythematosus: a longitudinal cohort analysis. ( Bro, ET; Ho, LY; Jannetto, PJ; Mok, CC; Singh, RJ, 2018)
"Vitamin D deficiency is highly prevalent in patients with SLE."1.43Severe vitamin D deficiency increases the risk for moderate to severe disease activity in Chinese patients with SLE. ( Gao, CC; Gao, GM; Li, TF; Liu, SY; Liu, ZS; Wu, ZZ; Zheng, ZH, 2016)
"Fatigue was quantified using a 0-10 visual analogue scale (VAS)."1.35Vitamin D deficiency in systemic lupus erythematosus: prevalence, predictors and clinical consequences. ( Aguirre, C; Egurbide, MV; Martinez-Berriotxoa, A; Olivares, N; Ruiz-Irastorza, G, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Stroehlein, JK1
Wallqvist, J1
Iannizzi, C1
Mikolajewska, A1
Metzendorf, MI1
Benstoem, C1
Meybohm, P1
Becker, M1
Skoetz, N1
Stegemann, M1
Piechotta, V1
Mok, CC1
Bro, ET1
Ho, LY1
Singh, RJ1
Jannetto, PJ1
Fangtham, M1
Petri, M1
Angelakis, E1
Oddoze, C1
Raoult, D1
Gao, CC1
Liu, SY1
Wu, ZZ1
Li, TF1
Gao, GM1
Liu, ZS1
Zheng, ZH1
Ruiz-Irastorza, G1
Egurbide, MV1
Olivares, N1
Martinez-Berriotxoa, A1
Aguirre, C1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention and Treatment With Calcifediol of COVID-19 Coronavirus-induced Acute Respiratory Syndrome (SARS)[NCT04366908]Phase 2517 participants (Actual)Interventional2020-05-07Completed
Vitamin D Supplementation in Patients With COVID-19: A Randomized, Double-blind, Placebo-controlled Trial[NCT04449718]240 participants (Actual)Interventional2020-06-01Completed
Short Term, High Dose Vitamin D Supplementation for COVID-19 Disease: Double Blind, Controlled, Study[NCT04459247]40 participants (Actual)Interventional2020-06-15Completed
Personalised Pharmacological Approach to the Tapering of Corticosteroid Doses in Systemic Lupus Patients Treated With Prednisone[NCT03187743]72 participants (Actual)Interventional2018-04-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydroxychloroquine and Deficiency, Vitamin D

ArticleYear
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
Vitamin D supplementation for the treatment of COVID-19: a living systematic review.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: 25-Hydroxyvitamin D 2; Adrenal Cortex Hormones; Adult; Azithromycin; Bias; Calcifediol; Cause of Dea

2021
2013 update: Hopkins lupus cohort.
    Current rheumatology reports, 2013, Volume: 15, Issue:9

    Topics: Antirheumatic Agents; Cardiovascular Diseases; Cognition Disorders; Cohort Studies; Creatinine; Gluc

2013

Other Studies

4 other studies available for hydroxychloroquine and Deficiency, Vitamin D

ArticleYear
Serum 25-hydroxyvitamin D3 levels and flares of systemic lupus erythematosus: a longitudinal cohort analysis.
    Clinical rheumatology, 2018, Volume: 37, Issue:10

    Topics: Adult; Calcifediol; Female; Humans; Hydroxychloroquine; Longitudinal Studies; Lupus Erythematosus, S

2018
Vitamin D and prolonged treatment with photosensitivity-associated antibiotics.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Adult; Aged; Anti-Bacterial Agents; Doxycycline; Endocarditis; Female; Humans; Hydroxychloroquine; M

2013
Severe vitamin D deficiency increases the risk for moderate to severe disease activity in Chinese patients with SLE.
    Lupus, 2016, Volume: 25, Issue:11

    Topics: Adult; Calcifediol; China; Cross-Sectional Studies; Female; Humans; Hydroxychloroquine; Lupus Erythe

2016
Vitamin D deficiency in systemic lupus erythematosus: prevalence, predictors and clinical consequences.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:6

    Topics: Adult; Age Factors; Antirheumatic Agents; Calcifediol; Cross-Sectional Studies; Fatigue; Female; Hum

2008