Page last updated: 2024-10-28

hydroxychloroquine and DRESS Syndrome

hydroxychloroquine has been researched along with DRESS Syndrome in 6 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"Background: Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) or drug-induced hypersensitivity (DIHS) is a rare and feared complication of frequently used medications such as anticonvulsants, sulfonamides, and allopurinol."5.51Pustular DRESS Syndrome Secondary to Hydroxychloroquine With EBV Reactivation ( Girijala, RL; Goldberg, LH; Kwak, Y; Patel, DB; Siddiqi, I; Wright, D, 2019)
" Current Condition: He started 8 days after ingestion of hydroxychloroquine for probable SARS-COV-2 infection, with headache, facial and neck edema, desquamative dermatosis on trunk and upper extremities, went to private clinic with torpid evolution sent to third level for increased facial and neck edema, which merited orotracheal intubation, management with intravenous steroids and antihistamines."4.31[Caso clínico: síndrome de DRESS por hidroxicloroquina]. ( Armenta-Morales, J; Caballero-López, C; López-García, A; Pacheco-Jiménez, Y; Papaqui-Tapia, J; Ríos-López, J; Rivero-Yeverino, D, 2023)
" This patient was diagnosed with drug rash with eosinophilia and systemic symptoms syndrome 4 weeks after starting sulfasalazine and 5 weeks after starting hydroxychloroquine for rheumatoid arthritis."4.12Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report. ( Hyser, E, 2022)
"Background: Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) or drug-induced hypersensitivity (DIHS) is a rare and feared complication of frequently used medications such as anticonvulsants, sulfonamides, and allopurinol."1.51Pustular DRESS Syndrome Secondary to Hydroxychloroquine With EBV Reactivation ( Girijala, RL; Goldberg, LH; Kwak, Y; Patel, DB; Siddiqi, I; Wright, D, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's5 (83.33)2.80

Authors

AuthorsStudies
Hyser, E1
Pacheco-Jiménez, Y1
Ríos-López, J1
Caballero-López, C1
López-García, A1
Rivero-Yeverino, D1
Papaqui-Tapia, J1
Armenta-Morales, J1
Schwartz, RA1
Janniger, CK1
Grandolfo, M1
Romita, P1
Bonamonte, D1
Cazzato, G1
Hansel, K1
Stingeni, L1
Conforti, C1
Giuffrida, R1
Foti, C1
Castro Jiménez, A1
Navarrete Navarrete, N1
Gratacós Gómez, AR1
Florido López, F1
García Rodríguez, R1
Gómez Torrijos, E1
Girijala, RL1
Siddiqi, I1
Kwak, Y1
Wright, D1
Patel, DB1
Goldberg, LH1

Reviews

1 review available for hydroxychloroquine and DRESS Syndrome

ArticleYear
Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine.
    Dermatologic therapy, 2020, Volume: 33, Issue:3

    Topics: Acute Generalized Exanthematous Pustulosis; Adrenal Cortex Hormones; Coronavirus Infections; COVID-1

2020

Other Studies

5 other studies available for hydroxychloroquine and DRESS Syndrome

ArticleYear
Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report.
    Journal of medical case reports, 2022, Sep-05, Volume: 16, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Drug Hypersensitivity Syndrome; Eosinophilia; E

2022
[Caso clínico: síndrome de DRESS por hidroxicloroquina].
    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 2023, Volume: 70, Issue:4

    Topics: Adult; Drug Hypersensitivity Syndrome; Edema; Eosinophilia; Humans; Hydroxychloroquine; Male; Steroi

2023
Drug reaction with eosinophilia and systemic symptoms syndrome to hydroxychloroquine, an old drug in the spotlight in the COVID-19 era.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Aged; Antimalarials; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Dru

2020
First case of DRESS syndrome caused by hydroxychloroquine with a positive patch test.
    Contact dermatitis, 2021, Volume: 84, Issue:1

    Topics: Adult; Drug Hypersensitivity Syndrome; Eosinophilia; Female; Humans; Hydroxychloroquine; Middle Aged

2021
Pustular DRESS Syndrome Secondary to Hydroxychloroquine With EBV Reactivation
    Journal of drugs in dermatology : JDD, 2019, Feb-01, Volume: 18, Issue:2

    Topics: Administration, Cutaneous; Antimalarials; Drug Hypersensitivity Syndrome; Epstein-Barr Virus Infecti

2019