Page last updated: 2024-10-28

hydroxychloroquine and Coronary Disease

hydroxychloroquine has been researched along with Coronary Disease in 11 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Aspirin has been shown to reduce the number of transient ischemic attacks (TIA), stroke and death in patients with multiple TIA."3.75Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells. ( Turpie, AG, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
El Boussadani, B1
Benajiba, C1
Aajal, A1
Ait Brik, A1
Ammour, O1
El Hangouch, J1
Oussama, O1
Oussama, B1
Tahiri, N1
Raissuni, Z1
BETETTO, D1
CRISTINA, P1
SPANIO, G1
Bouchier-Hayes, D1
Verstraete, M1
Turpie, AG2
Petri, M2
Lakatta, C1
Magder, L1
Goldman, D1
Hirsh, J3
Dettori, AG1
Pini, M1
Quintavalla, R1
Harker, LA1
Gent, M1
Genton, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005436]0 participants Observational1991-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for hydroxychloroquine and Coronary Disease

ArticleYear
[COVID-19 pandemia: Impact on the cariovascular system. Data of 1
    Annales de cardiologie et d'angeiologie, 2020, Volume: 69, Issue:3

    Topics: Antimalarials; Antiviral Agents; Azithromycin; Betacoronavirus; Cardiomyopathies; Cardiovascular Dis

2020
[Critical evaluation of the usefulness of drugs inhibiting platelet function in the prevention of postoperative deep venous thrombosis and in ischemic cardiopathy].
    Recenti progressi in medicina, 1980, Volume: 68, Issue:4

    Topics: Anticoagulants; Aspirin; Clofibrate; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Flurbiprof

1980
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
Detection of coronary artery disease and the role of traditional risk factors in the Hopkins Lupus Cohort.
    Lupus, 2000, Volume: 9, Issue:3

    Topics: Anti-Inflammatory Agents; Cohort Studies; Coronary Disease; Female; Humans; Hydroxychloroquine; Hypo

2000
Platelet suppressive therapy.
    British medical bulletin, 1978, Volume: 34, Issue:2

    Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coro

1978
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
[Treatment with antiplatelet drugs. Current status of knowledge].
    Recenti progressi in medicina, 1979, Volume: 67, Issue:3

    Topics: Aspirin; Blood Platelet Disorders; Cerebrovascular Disorders; Clofibrate; Coronary Disease; Dextrans

1979
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975

Trials

3 trials available for hydroxychloroquine and Coronary Disease

ArticleYear
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975

Other Studies

3 other studies available for hydroxychloroquine and Coronary Disease

ArticleYear
[THE USE OF HYDROXYCHLOROQUINE IN THE TREATMENT OF VASCULAR DISEASES].
    Minerva medica, 1963, Jul-21, Volume: 54

    Topics: Arteriosclerosis; Arteritis; Blood Proteins; Cholesterol; Coronary Disease; Fibrinogen; Humans; Hydr

1963
Drugs in the treatment of thrombo-embolic disease--part I.
    Irish medical journal, 1983, Volume: 76, Issue:2

    Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Platelets; Carotid Artery Diseases; Cerebrovasc

1983
Effect of prednisone and hydroxychloroquine on coronary artery disease risk factors in systemic lupus erythematosus: a longitudinal data analysis.
    The American journal of medicine, 1994, Volume: 96, Issue:3

    Topics: Adult; Blood Pressure; Body Weight; Cholesterol; Coronary Disease; Female; Humans; Hydroxychloroquin

1994