hydroxychloroquine has been researched along with Corneal Diseases in 11 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antimalarial drugs including chloroquine, its less toxic quinolone-derivative hydroxychloroquine (HCQ), and quinacrine have become cornerstones in the treatment of autoimmune diseases including systemic lupus, rheumatoid arthritis, sarcoidosis, and Sjogren syndrome; cutaneous disorders, antiphospholipid syndrome, and have recently been employed at higher dioses in oncology." | 2.58 | Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update. ( Abdulaziz, N; McCune, WJ; Shah, AR, 2018) |
| "The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients." | 1.62 | Evaluation of corneal safety in systemic lupus erythematosus patients undergoing long-term hydroxychloroquine treatment. ( Akyol, L; Alakuş, MF; Balcı, MA; Çağlayan, M; Dağ, U; Öncül, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Çağlayan, M | 1 |
| Akyol, L | 1 |
| Balcı, MA | 1 |
| Öncül, H | 1 |
| Alakuş, MF | 1 |
| Dağ, U | 1 |
| Abdulaziz, N | 1 |
| Shah, AR | 1 |
| McCune, WJ | 1 |
| Kondo, M | 1 |
| Shinoda, K | 1 |
| Matsumoto, CS | 1 |
| Yokogawa, N | 1 |
| Terasaki, H | 1 |
| Dosso, A | 1 |
| Rungger-Brändle, E | 1 |
| Lanham, JG | 1 |
| Hughes, GR | 1 |
| Easterbrook, M | 2 |
| Shipley, M | 2 |
| Silman, A | 2 |
| Lozier, JR | 1 |
| Friedlaender, MH | 1 |
| Cullen, AP | 1 |
| Chou, BR | 1 |
4 reviews available for hydroxychloroquine and Corneal Diseases
| Article | Year |
|---|---|
Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update.
Topics: Antirheumatic Agents; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Drug Administ | 2018 |
Antimalarial therapy in SLE.
Topics: Antimalarials; Binding Sites; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Femal | 1982 |
Ophthalmological monitoring for hydroxychloroquine toxicity: a scientific review of available data.
Topics: Antirheumatic Agents; Corneal Diseases; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Dru | 1997 |
Complications of antimalarial therapy.
Topics: Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Ciliary Body; Color Perception; Corneal D | 1989 |
7 other studies available for hydroxychloroquine and Corneal Diseases
| Article | Year |
|---|---|
Evaluation of corneal safety in systemic lupus erythematosus patients undergoing long-term hydroxychloroquine treatment.
Topics: Aberrometry; Adolescent; Adult; Cornea; Corneal Diseases; Corneal Pachymetry; Cross-Sectional Studie | 2021 |
[Guide for Clinical Use of Hydroxychloroquine].
Topics: Clinical Trials as Topic; Contraindications; Corneal Diseases; Humans; Hydroxychloroquine; Practice | 2016 |
In vivo confocal microscopy in hydroxychloroquine-induced keratopathy.
Topics: Adult; Antirheumatic Agents; Cornea; Corneal Diseases; Female; Humans; Hydroxychloroquine; Inclusion | 2007 |
Screening for antimalarial toxicity.
Topics: Chloroquine; Color Perception Tests; Corneal Diseases; Humans; Hydroxychloroquine; Retinal Diseases; | 1993 |
Should patients on hydroxychloroquine have their eyes examined regularly?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Corneal Diseases; Diagnostic Tests, Routine; Dose-Respo | 1997 |
Ocular effects and safety of antimalarial agents.
Topics: Antimalarials; Chloroquine; Corneal Diseases; Drug Administration Schedule; Electrooculography; Elec | 1988 |
Keratopathy with low dose chloroquine therapy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Chloroquine; Corneal Diseases; Fe | 1986 |