Page last updated: 2024-10-28

hydroxychloroquine and Communicable Diseases

hydroxychloroquine has been researched along with Communicable Diseases in 4 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Communicable Diseases: An illness caused by an infectious agent or its toxins that occurs through the direct or indirect transmission of the infectious agent or its products from an infected individual or via an animal, vector or the inanimate environment to a susceptible animal or human host.

Research Excerpts

ExcerptRelevanceReference
" Chloroquine and hydroxychloroquine, with an original indication to prevent or cure malaria, have been successfully used to treat several infectious (HIV, Q fever, Whipple's disease, fungal infections), rheumatological (systemic lupus erythematosus, antiphospholipid antibody syndrome, rheumatoid arthritis, Sjögren's syndrome), and other immunological diseases."4.98Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. ( Koudriavtseva, T; Plantone, D, 2018)
" Additional liabilities of these medications include pharmacokinetic profiles that require extended dosing to achieve therapeutic tissue concentrations."2.66Nanomedicine Reformulation of Chloroquine and Hydroxychloroquine. ( Crist, RM; Stern, ST; Stevens, DM, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Hernandez-Cardenas, C1
Thirion-Romero, I1
Rodríguez-Llamazares, S1
Rivera-Martinez, NE1
Meza-Meneses, P1
Remigio-Luna, A1
Perez-Padilla, R1
Barbosa, AN1
Chebabo, A1
Starling, C1
Pérez, C1
Cunha, CA1
de Luna, D1
Nunes, EP1
Zambrano, G1
Ferreira, JC1
Croda, J1
Falavigna, M1
Gomes-da-Silva, MM1
Thormann, M1
Cimerman, S1
Parahiba, SM1
Tanni, S1
Bernardo, WM1
Rodriguez-Morales, AJ1
Stevens, DM1
Crist, RM1
Stern, ST1
Plantone, D1
Koudriavtseva, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Proflaxis for Healthcare Professionals Using Hydroxychloroquine Plus Vitamin Combining Vitamins C, D and Zinc During COVID-19 Pandemia: An Observational Study[NCT04326725]80 participants (Anticipated)Observational2020-03-20Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydroxychloroquine and Communicable Diseases

ArticleYear
Pan-American Guidelines for the treatment of SARS-CoV-2/COVID-19: a joint evidence-based guideline of the Brazilian Society of Infectious Diseases (SBI) and the Pan-American Association of Infectious Diseases (API).
    Annals of clinical microbiology and antimicrobials, 2023, Aug-07, Volume: 22, Issue:1

    Topics: Antiviral Agents; Brazil; Communicable Diseases; COVID-19; Humans; Hydroxychloroquine; Ivermectin; P

2023
Nanomedicine Reformulation of Chloroquine and Hydroxychloroquine.
    Molecules (Basel, Switzerland), 2020, Dec-31, Volume: 26, Issue:1

    Topics: Animals; Antimalarials; Chloroquine; Communicable Diseases; Drug Compounding; Humans; Hydroxychloroq

2020
Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.
    Clinical drug investigation, 2018, Volume: 38, Issue:8

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineoplastic Agents; Antirheumatic

2018

Trials

1 trial available for hydroxychloroquine and Communicable Diseases

ArticleYear
Hydroxychloroquine for the treatment of severe respiratory infection by COVID-19: A randomized controlled trial.
    PloS one, 2021, Volume: 16, Issue:9

    Topics: Adult; Antiviral Agents; Communicable Diseases; COVID-19; COVID-19 Drug Treatment; Double-Blind Meth

2021