hydroxychloroquine has been researched along with Colitis in 6 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine, which is a potent inhibitor of leucocyte motility, effectively prevents the acute inflammatory infiltrate in this experimental colitis model and therefore merits trial in human ulcerative colitis." | 5.26 | Inhibition of leucocyte motility and prevention of immune-complex experimental colitis by hydroxychloroquine. ( Brown, DJ; Jewell, DP; McLaughlin, JE; Nuttall, LA; Rhodes, JM, 1982) |
| "Hydroxychloroquine, which is a potent inhibitor of leucocyte motility, effectively prevents the acute inflammatory infiltrate in this experimental colitis model and therefore merits trial in human ulcerative colitis." | 1.26 | Inhibition of leucocyte motility and prevention of immune-complex experimental colitis by hydroxychloroquine. ( Brown, DJ; Jewell, DP; McLaughlin, JE; Nuttall, LA; Rhodes, JM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sattar, Y | 1 |
| Connerney, M | 1 |
| Rauf, H | 1 |
| Saini, M | 1 |
| Ullah, W | 1 |
| Mamtani, S | 1 |
| Syed, U | 1 |
| Luddington, S | 1 |
| Walfish, A | 1 |
| Carvalho, A | 1 |
| Alqusairi, R | 1 |
| Adams, A | 1 |
| Paul, M | 1 |
| Kothari, N | 1 |
| Peters, S | 1 |
| DeBenedet, AT | 1 |
| Yao, J | 1 |
| Xie, J | 1 |
| Xie, B | 1 |
| Li, Y | 1 |
| Jiang, L | 1 |
| Sui, X | 1 |
| Zhou, X | 1 |
| Pan, H | 1 |
| Han, W | 1 |
| Rhodes, JM | 1 |
| McLaughlin, JE | 1 |
| Brown, DJ | 1 |
| Nuttall, LA | 1 |
| Jewell, DP | 1 |
| Kirch, W | 1 |
| Dührsen, U | 1 |
| Ohnhaus, EE | 1 |
| Greif, S | 1 |
6 other studies available for hydroxychloroquine and Colitis
| Article | Year |
|---|---|
Three Cases of COVID-19 Disease With Colonic Manifestations.
Topics: Adult; Aged; Anti-Bacterial Agents; Antimalarials; Astringents; Azithromycin; Betacoronavirus; Colit | 2020 |
SARS-CoV-2 Gastrointestinal Infection Causing Hemorrhagic Colitis: Implications for Detection and Transmission of COVID-19 Disease.
Topics: Aged; Antimalarials; Betacoronavirus; Colitis; Colonoscopy; Coronavirus Infections; COVID-19; Diagno | 2020 |
Therapeutic effect of hydroxychloroquine on colorectal carcinogenesis in experimental murine colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogenesis; Cell Proliferation; Colitis; Color | 2016 |
Inhibition of leucocyte motility and prevention of immune-complex experimental colitis by hydroxychloroquine.
Topics: Animals; Antigen-Antibody Complex; Cell Survival; Chemotaxis, Leukocyte; Colitis; Dose-Response Rela | 1982 |
[Therapy of Weber-Christian disease].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimetabolites; Bed Rest; Clindamycin; Colitis; | 1985 |
[Experiences with the eubiotic Mexaform in intestinal disorders of various origins].
Topics: Anti-Infective Agents; Colitis; Female; Hepatitis A; Humans; Hydroxychloroquine; Intestinal Diseases | 1966 |