hydroxychloroquine has been researched along with Colitis, Granulomatous in 8 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate pregnancy safety of hydroxychloroquine (HCQ) for rheumatologic diseases." | 7.79 | Pregnancy outcome following in utero exposure to hydroxychloroquine: a prospective comparative observational study. ( Blyakhman, S; Diav-Citrin, O; Ornoy, A; Shechtman, S, 2013) |
| "To evaluate pregnancy safety of hydroxychloroquine (HCQ) for rheumatologic diseases." | 3.79 | Pregnancy outcome following in utero exposure to hydroxychloroquine: a prospective comparative observational study. ( Blyakhman, S; Diav-Citrin, O; Ornoy, A; Shechtman, S, 2013) |
| "coli are present in Crohn's disease, but their role in pathogenesis is uncertain." | 3.01 | Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn's Disease. ( Butterworth, J; Culshaw, K; Dallal, H; Flanagan, PK; Hart, A; Horgan, GW; Iqbal, T; Mansfield, J; Martin, K; Parkes, M; Probert, C; Rhodes, JM; Subramanian, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Rhodes, JM | 2 |
| Subramanian, S | 2 |
| Flanagan, PK | 2 |
| Horgan, GW | 1 |
| Martin, K | 1 |
| Mansfield, J | 1 |
| Parkes, M | 1 |
| Hart, A | 1 |
| Dallal, H | 1 |
| Iqbal, T | 1 |
| Butterworth, J | 1 |
| Culshaw, K | 1 |
| Probert, C | 1 |
| Diav-Citrin, O | 1 |
| Blyakhman, S | 1 |
| Shechtman, S | 1 |
| Ornoy, A | 1 |
| Chiewchengchol, D | 1 |
| Wright, HL | 1 |
| Edwards, SW | 1 |
| Alswied, A | 1 |
| Satsangi, J | 1 |
| Campbell, BJ | 1 |
| Louis, E | 1 |
| Belaïche, J | 1 |
| Ochonisky, S | 1 |
| Bonvalet, D | 1 |
| Caron, C | 1 |
| Kornhauser, R | 1 |
| Vignon-Pennamen, MD | 1 |
| Dubertret, L | 1 |
| Mayer, L | 1 |
| Mallinson, CN | 1 |
| Candy, JC | 1 |
| Cowan, R | 1 |
| Prior, A | 1 |
| Ehrenpreis, T | 1 |
| Gierup, J | 1 |
| Lagercrantz, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Randomised Study to Compare Combination Antibiotic Therapy (Ciprofloxacin, Doxycycline and Hydroxychloroquine) With Standard Therapy (Budesonide) in the Treatment of Active Crohn's Disease[NCT01783106] | Phase 2 | 59 participants (Actual) | Interventional | 2014-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxychloroquine and Colitis, Granulomatous
| Article | Year |
|---|---|
Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn's Disease.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Budesonide; Ciprofloxacin; Crohn Disease; Cross-Ove | 2021 |
7 other studies available for hydroxychloroquine and Colitis, Granulomatous
| Article | Year |
|---|---|
Pregnancy outcome following in utero exposure to hydroxychloroquine: a prospective comparative observational study.
Topics: Abnormalities, Drug-Induced; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Birth Weight; Crohn | 2013 |
Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D.
Topics: Adult; Animals; Cells, Cultured; Crohn Disease; Cytokines; Drug Therapy, Combination; Enzyme Inhibit | 2015 |
Hydroxychloroquine (Plaquenil) for recurrence prevention of Crohn's disease after curative surgery.
Topics: Crohn Disease; Humans; Hydroxychloroquine; Postoperative Care; Recurrence | 1995 |
[Granulomatous cheilitis with cutaneous extension in Crohn disease. Regression with hydroxychloroquine].
Topics: Adult; Anus Diseases; Crohn Disease; Erythema; Female; Humans; Hydroxychloroquine; Melkersson-Rosent | 1992 |
The role of the epithelial cell in immunoregulation: pathogenetic and therapeutic implications.
Topics: Antigen-Presenting Cells; Crohn Disease; Epithelium; Humans; Hydroxychloroquine; Intestines | 1990 |
Two first degree relatives with dilatation of the colon due to Crohn's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Azathioprine; Body Weight; Colectomy; Colitis, Ulcer | 1973 |
[Chronic regional enterocolitis (Crohn's disease) in juveniles].
Topics: Adolescent; Blood Transfusion; Child; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; F | 1967 |