hydroxychloroquine has been researched along with Cirrhosis in 11 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) has been adapted for the treatment of autoimmune diseases; however, the potential mechanism underlying the role of HCQ in renal fibrosis remains unclear." | 5.72 | Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway. ( Bai, F; Fan, J; Feng, F; Li, D; Liu, L; Sun, N; Yang, H; Yang, X; Yu, K; Zhang, Y, 2022) |
| "Hydroxychloroquine (HCQ) has been adapted for the treatment of autoimmune diseases; however, the potential mechanism underlying the role of HCQ in renal fibrosis remains unclear." | 1.72 | Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway. ( Bai, F; Fan, J; Feng, F; Li, D; Liu, L; Sun, N; Yang, H; Yang, X; Yu, K; Zhang, Y, 2022) |
| "FFA is an increasingly common form of scarring hair loss, but the origin remains unknown." | 1.39 | Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University. ( Bazakas, A; Ladizinski, B; Olsen, EA; Selim, MA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Yu, K | 1 |
| Feng, F | 1 |
| Zhang, Y | 2 |
| Bai, F | 1 |
| Sun, N | 1 |
| Fan, J | 1 |
| Liu, L | 1 |
| Yang, H | 1 |
| Yang, X | 1 |
| Devjani, S | 1 |
| Ezemma, O | 1 |
| Jothishankar, BA | 1 |
| Kelley, KJ | 1 |
| Senna, M | 1 |
| Chen, X | 1 |
| Yu, Q | 1 |
| Liu, Y | 1 |
| Sheng, Q | 1 |
| Shi, K | 1 |
| Wang, Y | 1 |
| Li, M | 1 |
| Zhang, Z | 1 |
| He, Q | 1 |
| Gochuico, BR | 1 |
| Ziegler, SG | 1 |
| Ten, NS | 1 |
| Balanda, NJ | 1 |
| Mason, CE | 1 |
| Zumbo, P | 1 |
| Evans, CA | 1 |
| Van Waes, C | 1 |
| Gahl, WA | 1 |
| Malicdan, MCV | 1 |
| Suchonwanit, P | 1 |
| Pakornphadungsit, K | 1 |
| Leerunyakul, K | 1 |
| Khunkhet, S | 1 |
| Sriphojanart, T | 1 |
| Rojhirunsakool, S | 1 |
| Starace, M | 1 |
| Orlando, G | 1 |
| Alessandrini, A | 1 |
| Baraldi, C | 1 |
| Bruni, F | 1 |
| Piraccini, BM | 1 |
| Greenhaw, BN | 1 |
| Cook, J | 1 |
| Oikarinen, A | 1 |
| Chiang, C | 1 |
| Sah, D | 1 |
| Cho, BK | 1 |
| Ochoa, BE | 1 |
| Price, VH | 1 |
| Ladizinski, B | 1 |
| Bazakas, A | 1 |
| Selim, MA | 1 |
| Olsen, EA | 1 |
| Elmore, S | 1 |
| Lanning, L | 1 |
| Allison, N | 1 |
| Vallant, M | 1 |
| Nyska, A | 1 |
11 other studies available for hydroxychloroquine and Cirrhosis
| Article | Year |
|---|---|
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Topics: Animals; Epithelial-Mesenchymal Transition; Female; Fibrosis; Humans; Hydroxychloroquine; Kidney; Ma | 2022 |
Assessment of hydroxychloroquine use and QT interval duration in female patients with frontal fibrosing alopecia.
Topics: Alopecia; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus | 2023 |
Synergistic cytotoxicity and co-autophagy inhibition in pancreatic tumor cells and cancer-associated fibroblasts by dual functional peptide-modified liposomes.
Topics: Animals; Antineoplastic Agents; Autophagy; Cancer-Associated Fibroblasts; Carcinoma, Pancreatic Duct | 2019 |
A comprehensive, multidisciplinary, precision medicine approach to discover effective therapy for an undiagnosed, progressive, fibroinflammatory disease.
Topics: Adolescent; Bronchoalveolar Lavage Fluid; Disease Progression; Female; Fibroblasts; Fibrosis; Gene E | 2020 |
Frontal fibrosing alopecia in Asians: a retrospective clinical study.
Topics: 5-alpha Reductase Inhibitors; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Alopecia; Asi | 2020 |
Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Administration, Topical; Adult; Aged; Alopecia A | 2020 |
Painful subcutaneous fibrosis: a complication after high-intensity focused ultrasound for lipolysis.
Topics: Enzyme Inhibitors; Female; Fibrosis; High-Intensity Focused Ultrasound Ablation; Humans; Hydroxychlo | 2015 |
Hydroxychloroquine induces autophagic cell death of human dermal fibroblasts: implications for treating fibrotic skin diseases.
Topics: Antimalarials; Autophagy; Cell Proliferation; Dermis; Dose-Response Relationship, Drug; Fibroblasts; | 2009 |
Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system.
Topics: Adult; Alopecia; Cicatrix; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus; Male; Middle | 2010 |
Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Alopecia; Anti-Bacterial Agents; Azasteroids; Cicatrix; D | 2013 |
The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site.
Topics: Adenoviridae; Animals; Antirheumatic Agents; Female; Fibrosis; Gene Transfer Techniques; Genetic Vec | 2006 |