Page last updated: 2024-10-28

hydroxychloroquine and Chronic Disease

hydroxychloroquine has been researched along with Chronic Disease in 65 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Hydroxychloroquine (HCQ) is an immunosuppressive lysosomotropic amine that has activity against graft-versus-host disease (GVHD)."9.12A randomized double-blind trial of hydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. ( Adkins, D; Devine, SM; Dipersio, JF; Fong, T; Goodnough, LT; Graubert, T; Khoury, HJ; Lopez, S; Shenoy, S; Tomasson, M; Trinkaus, K; Vij, R, 2007)
"The aim of the chronic autoimmune urticaria study and evaluation was to evaluate the efficacy of hydroxychloroquine in patients with chronic idiopathic urticaria."9.11Impact of hydroxychloroquine therapy on chronic urticaria: chronic autoimmune urticaria study and evaluation. ( Bonfield, J; Boyle, MJ; Dobson, P; Loewenthal, M; Reeves, GE, 2004)
"To evaluate retinal toxicity in patients treated with high-dose hydroxychloroquine (HCQ) (Plaquenil, Sanofi Pharmaceuticals) for chronic graft-versus-host disease (GVHD)."7.81Retinal toxicity of high-dose hydroxychloroquine in patients with chronic graft-versus-host disease. ( Boyd, S; Easterbrook, M; Hammoudi, DS; Krema, H; Lipton, JH; Navajas, EV; Simpson, ER, 2015)
"Hydroxychloroquine (HCQ) is a 4-aminoquinoline antimalarial drug used for the treatment of autoimmune diseases."6.69Hydroxychloroquine for the treatment of chronic graft-versus-host disease. ( Boyer, M; Cahill, R; Chan, KW; Cirenza, E; Frankel, S; Gehan, E; Gilman, AL; Goldman, FD; Mazumder, A; Mogul, A; Morris, C; Schultz, K, 2000)
"A 2-week treatment with ceftriaxone followed by a 12-week regimen of doxycycline or clarithromycin/hydroxychloroquine did not lead to better cognitive performance compared to a 2-week regimen of ceftriaxone in patients with Lyme disease-attributed persistent symptoms."5.30Effect of prolonged antibiotic treatment on cognition in patients with Lyme borreliosis. ( Berende, A; Evers, AWM; Kessels, RPC; Kullberg, BJ; Ter Hofstede, HJM; van Middendorp, H; Vogelaar, ML; Vos, FJ, 2019)
"Hydroxychloroquine (HCQ) is an immunosuppressive lysosomotropic amine that has activity against graft-versus-host disease (GVHD)."5.12A randomized double-blind trial of hydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. ( Adkins, D; Devine, SM; Dipersio, JF; Fong, T; Goodnough, LT; Graubert, T; Khoury, HJ; Lopez, S; Shenoy, S; Tomasson, M; Trinkaus, K; Vij, R, 2007)
"The aim of the chronic autoimmune urticaria study and evaluation was to evaluate the efficacy of hydroxychloroquine in patients with chronic idiopathic urticaria."5.11Impact of hydroxychloroquine therapy on chronic urticaria: chronic autoimmune urticaria study and evaluation. ( Bonfield, J; Boyle, MJ; Dobson, P; Loewenthal, M; Reeves, GE, 2004)
"A morning standard dose of 250 mcg tetracosactide (Synacthen test) was given in 25 consecutive patients (13 rheumatoid arthritis, 2 psoriatic arthritis, 5 systemic lupus erythematosus, 2 dermatomyositis, 1 systemic sclerosis, 2 temporal arteritis) at the time of relapse upon small reductions (1-2 mg daily) of low prednisolone dose (<7."4.12Impaired adrenal cortex reserve in patients with rheumatic and musculoskeletal diseases who relapse upon tapering of low glucocorticoid dose. ( Filippa, MG; Panopoulos, S; Sfikakis, PP; Spanos, E; Spanos, G; Tektonidou, MG; Yavropoulou, MP, 2022)
"To evaluate retinal toxicity in patients treated with high-dose hydroxychloroquine (HCQ) (Plaquenil, Sanofi Pharmaceuticals) for chronic graft-versus-host disease (GVHD)."3.81Retinal toxicity of high-dose hydroxychloroquine in patients with chronic graft-versus-host disease. ( Boyd, S; Easterbrook, M; Hammoudi, DS; Krema, H; Lipton, JH; Navajas, EV; Simpson, ER, 2015)
"Chronic ulcerative stomatitis (CUS) is a rare disease of the mucous membranes with characteristics similar to other autoimmune diseases."2.82Clinical and immunological features of chronic ulcerative stomatitis: A systematic review. ( Palma, VM; Rados, PV; Schroeder, FMM; Visioli, F, 2022)
"Hydroxychloroquine (HCQ) is a 4-aminoquinoline antimalarial drug used for the treatment of autoimmune diseases."2.69Hydroxychloroquine for the treatment of chronic graft-versus-host disease. ( Boyer, M; Cahill, R; Chan, KW; Cirenza, E; Frankel, S; Gehan, E; Gilman, AL; Goldman, FD; Mazumder, A; Mogul, A; Morris, C; Schultz, K, 2000)
"The novel coronavirus disease 2019, otherwise known as COVID-19, is a global pandemic with primary respiratory manifestations in those who are symptomatic."2.66Approach to Acute Cardiovascular Complications in COVID-19 Infection. ( Abdalla, M; Anstey, DE; Fried, JA; Givens, RC; Karmpaliotis, D; Kirtane, AJ; Kodali, SK; Kumaraiah, D; Leon, MB; Masoumi, A; Rabbani, LE; Ranard, LS; Sayer, G; Schwartz, A; Takeda, K; Uriel, N, 2020)
"Chronic ulcerative stomatitis (CUS) is a mucocutaneous disorder which is characterised by persistent oral mucosal ulceration."2.47Chronic ulcerative stomatitis: a distinct clinical entity? ( Fourie, J; McEachen, SC; van Heerden, WF; van Zyl, A, 2011)
"Selection of patients with chronic immune thrombocytopenia from the French national prospective cohort of pediatric autoimmune cytopenia OBS'CEREVANCE and VIGICAIRE study, treated by splenectomy, hydroxychloroquine, azathioprine, or rituximab as a first second-line treatment."1.62Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation. ( Abou Chahla, W; Aladjidi, N; Armari-Alla, C; Barlogis, V; Bayart, S; Bertrand, Y; Cheikh, N; Ducassou, S; Fernandes, H; Guitton, C; Kherfellah, D; Laghouati, S; Leblanc, T; Leverger, G; Pasquet, M; Pellier, I; Savel, H; Thiébaut, R; Thomas, C; Vassal, G, 2021)
"Treatment of chronic Q fever with TET plus QNL appears to be a safe alternative for TET plus HCQ, for example, if TET plus HCQ cannot be tolerated due to side effects."1.48Treatment of Chronic Q Fever: Clinical Efficacy and Toxicity of Antibiotic Regimens. ( Bleeker-Rovers, CP; de Regt, MJA; Hoepelman, AIM; Kampschreur, LM; Oosterheert, JJ; van Roeden, SE; Wever, PC, 2018)
"Hydroxychloroquine was the most common (76%), followed by azathioprine (15%) and methotrexate (13%)."1.43Drugs used in incident systemic lupus erythematosus - results from the Finnish nationwide register 2000-2007. ( Elfving, P; Kaipiainen-Seppänen, O; Kautiainen, H; Pohjolainen, T; Puolakka, K; Virta, LJ, 2016)
"Treatment with Sulfasalazine with and without methotrexate produced good response in 71."1.37Post-chikungunya chronic arthritis--our experience with DMARDs over two year follow up. ( Ganu, AS; Ganu, MA, 2011)
"Chronic ulcerative stomatitis (CUS) is a recently described condition with specific immunopathologic findings."1.35Chronic ulcerative stomatitis. ( Solomon, LW, 2008)
"Hydroxychloroquine alone was given in 4 and was effective in 3."1.33Chronic inflammation of the vagina: treatment and relationship to autoimmunity. ( Thomson, JC, 2005)
"Prednisone was used at a starting dose from about 0."1.33Muscle involvement in sarcoidosis: a retrospective and followup studies. ( Bardin, T; Berenbaum, F; Fayad, F; Lioté, F; Orcel, P, 2006)
"Chronic ulcerative stomatitis (CUS) is a mucocutaneous disease primarily involving mucosal surfaces, but occasionally may involve the skin."1.32Chronic ulcerative stomatitis: clinical, histopathologic, and immunopathologic findings. ( Aguirre, A; Costales-Spindler, A; Jividen, GJ; Kumar, V; Neiders, M; Solomon, LW; Zwick, MG, 2003)
" Hydroxychloroquine, given at a dosage of 200-400 mg/day, led to a complete and long-lasting remission."1.30Chronic ulcerative stomatitis. ( Kunzelmann, KH; Meurer, M; Plewig, G; Schaller, M; Wollenberg, A; Wörle, B, 1997)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19907 (10.77)18.7374
1990's9 (13.85)18.2507
2000's16 (24.62)29.6817
2010's21 (32.31)24.3611
2020's12 (18.46)2.80

Authors

AuthorsStudies
Schroeder, FMM1
Palma, VM1
Rados, PV1
Visioli, F1
Yavropoulou, MP1
Filippa, MG1
Panopoulos, S1
Spanos, E1
Spanos, G1
Tektonidou, MG1
Sfikakis, PP1
Khan, N1
Epstein, TG1
DuBuske, I1
Strobel, M1
Bernstein, DI1
Kaplan, AP1
Vastarella, M1
Patrì, A1
Annunziata, MC1
Cantelli, M1
Nappa, P1
Tasso, M1
Costa, L1
Caso, F1
Fabbrocini, G1
Ranard, LS1
Fried, JA1
Abdalla, M1
Anstey, DE1
Givens, RC1
Kumaraiah, D1
Kodali, SK1
Takeda, K1
Karmpaliotis, D1
Rabbani, LE1
Sayer, G1
Kirtane, AJ1
Leon, MB1
Schwartz, A1
Uriel, N1
Masoumi, A1
Györfi, AH1
Kopp, M1
May, M1
Vetter, M1
Uder, M1
Kremer, AE1
Schett, G1
Harrer, T1
Distler, JHW1
Husayn, SS1
Brown, JD1
Presley, CL1
Boghean, K1
Waller, JD1
Stoopler, ET1
Kulkarni, R1
Alawi, F1
Sollecito, TP1
Riou, M1
Marcot, C1
Canuet, M1
Renaud-Picard, B1
Chatron, E1
Porzio, M1
Dégot, T1
Hirschi, S1
Metz-Favre, C1
Kassegne, L1
Ederle, C1
Khayath, N1
Labani, A1
Leyendecker, P1
De Blay, F1
Kessler, R1
Tejada Cifuentes, F1
Lloret Callejo, Á1
Tirado Peláez, MJ1
Rubio Pulido, O1
Ruiz-Morote Aragón, M1
Fernández Urrusuno, R1
Muñoz Carreras, MI1
Méndez Esteban, MI1
Maestre Sánchez, V1
García Bonilla, A1
Paredero Dominguez, JM1
Arroyo Pineda, V1
Marco Tejón, E1
Romero Candel, G1
Fernández Marchante, AI1
Marco Del Rio, J1
Ortiz Martín, T1
López Sánchez, P1
Ducassou, S1
Fernandes, H1
Savel, H1
Bertrand, Y1
Leblanc, T1
Abou Chahla, W1
Pasquet, M1
Leverger, G1
Barlogis, V1
Thomas, C1
Bayart, S1
Pellier, I1
Armari-Alla, C1
Guitton, C1
Cheikh, N1
Kherfellah, D1
Vassal, G1
Thiébaut, R1
Laghouati, S1
Aladjidi, N1
Boonpiyathad, T1
Sangasapaviliya, A1
van Roeden, SE1
Bleeker-Rovers, CP1
de Regt, MJA1
Kampschreur, LM1
Hoepelman, AIM1
Wever, PC1
Oosterheert, JJ1
Iweala, OI1
Copenhaver, C1
Wu, EY1
Moran, TP1
Merkesdal, S1
Kirchhoff, T1
Jablonka, A1
Schmidt, RE1
Köhler, L1
Fardet, L1
Nazareth, I1
Petersen, I1
Berende, A1
Ter Hofstede, HJM1
Vos, FJ1
Vogelaar, ML1
van Middendorp, H1
Evers, AWM1
Kessels, RPC1
Kullberg, BJ1
Garrity, ST1
Jung, JY1
Zambrowski, O1
Pichi, F1
Su, D1
Arya, M1
Waheed, NK1
Duker, JS1
Chetrit, Y1
Miserocchi, E1
Giuffrè, C1
Kaden, TR1
Querques, G1
Souied, EH1
Freund, KB1
Sarraf, D1
Akamine, CM1
Perez, ML1
Lee, JH1
Ing, MB1
Navajas, EV1
Krema, H1
Hammoudi, DS1
Lipton, JH1
Simpson, ER1
Boyd, S1
Easterbrook, M1
Elfving, P1
Puolakka, K1
Kautiainen, H1
Virta, LJ1
Pohjolainen, T1
Kaipiainen-Seppänen, O1
Chasset, F1
Arnaud, L1
Costedoat-Chalumeau, N1
Zahr, N1
Bessis, D1
Francès, C1
Steurer, J1
Ravindran, V1
Alias, G1
Solomon, LW2
Palazzi, C1
D'Angelo, S1
Olivieri, I1
Chopra, A1
Anuradha, V1
Lagoo-Joshi, V1
Kunjir, V1
Salvi, S1
Saluja, M1
Günther, C1
Meurer, M2
Stein, A1
Viehweg, A1
Lee-Kirsch, MA1
Cuvelier, GD1
Kariminia, A2
Fujii, H1
Aslanian, S1
Wall, D1
Goldman, F1
Grupp, SA3
Dunn, SE1
Krailo, M2
Shapiro, LH1
Gilman, A1
Schultz, KR4
Pasadhika, S1
Fishman, GA1
Choi, D1
Shahidi, M1
Lee, HE1
Ko, JY1
Lee, CW1
Rozmus, J1
Wynne, K1
Satyanarayana, P1
Gilman, AL4
Goldman, FD3
Sale, GE1
Krailo, MD1
Chen, Z1
Langholz, B1
Jacobsohn, DA1
Chan, KW2
Ryan, RE1
Kellick, M1
Neudorf, SM1
Godder, K1
Sandler, ES1
Sahdev, I1
Sanders, JE1
Wall, DA1
Ganu, MA1
Ganu, AS1
Fourie, J1
van Heerden, WF1
McEachen, SC1
van Zyl, A1
Füessl, HS1
Stiefelhagen, P1
Aguirre, A1
Neiders, M1
Costales-Spindler, A1
Jividen, GJ1
Zwick, MG1
Kumar, V2
Reeves, GE1
Boyle, MJ1
Bonfield, J1
Dobson, P1
Loewenthal, M1
Fritzsche, M1
Bolaños-Meade, J1
Zhou, L1
Hoke, A1
Corse, A1
Vogelsang, G1
Wagner, KR1
Acharya, N1
Pineda, R2
Uy, HS2
Foster, CS2
Thomson, JC1
Healy, B1
Llewelyn, M1
Westmoreland, D1
Lloyd, G1
Brown, N1
Fayad, F1
Lioté, F1
Berenbaum, F1
Orcel, P1
Bardin, T1
Islam, MN1
Cohen, DM1
Ojha, J1
Stewart, CM1
Katz, J1
Bhattacharyya, I1
Fong, T1
Trinkaus, K1
Adkins, D1
Vij, R1
Devine, SM1
Tomasson, M1
Goodnough, LT1
Lopez, S1
Graubert, T1
Shenoy, S1
Dipersio, JF1
Khoury, HJ1
Mozziconacci, P1
Hayem, F1
Guy-Grand, D1
Callen, JP2
Nashel, DJ1
Ulmer, CC1
Coblyn, JS1
Taylor, P1
Alloway, JA1
Franks, LK1
Fan, LL1
Jarrett, P1
Goodfield, MJ1
Lewis, JE1
Beutner, EH2
Rostami, R1
Chorzelski, TP2
Sinha, RN1
Fraser, WD1
Casson, IF1
Wörle, B1
Wollenberg, A1
Schaller, M1
Kunzelmann, KH1
Plewig, G1
Shore, JW1
Polcharoen, W1
Jakobiec, FA1
Kossard, S1
Ma, DD1
Mogul, A1
Morris, C1
Boyer, M1
Cirenza, E1
Mazumder, A1
Gehan, E1
Cahill, R1
Frankel, S1
Schultz, K1
Parodi, A1
Schosser, R1
Guin, J1
Cardo, PP1
Maciejowska, E1
Valeski, JE1
Spann, CR1
Klein, JB1
Kulick, KB1
Bossa, G1
Giordano, M1
Steffen, J1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Impaired Functional Reserve of Adrenal Cortex May Associate With difficult-to Treat RA: Can a Disturbed Cortisol Circadian Rhythm Serve as a Predictor of Difficult-to-treat RA?[NCT05671627]50 participants (Anticipated)Observational2022-02-02Recruiting
"French National Cohort of Patients With Pediatric-onset of Autoimmune Cytopenia (OBS'CEREVANCE Cohort)"[NCT05937828]3,500 participants (Anticipated)Observational [Patient Registry]2010-09-01Recruiting
Persistent Lyme Empiric Antibiotic Study Europe. A Prospective, Randomised Study Comparing Two Prolonged Oral Antibiotic Strategies After Initial Intravenous Ceftriaxone Therapy for Patients With Symptoms of Proven or Possible Persistent Lyme Disease[NCT01207739]Phase 4280 participants (Actual)Interventional2010-09-30Completed
Phase III Trial of Hydroxychloroquine + Standard Therapy for Chronic Graft-Versus-Host Disease[NCT00031824]Phase 382 participants (Actual)Interventional2002-04-30Completed
Hydroxychloroquine Efficacy in Chronic Urticaria[NCT01073852]0 participants (Actual)Interventional2011-06-30Withdrawn (stopped due to withdrawn, not funded)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for hydroxychloroquine and Chronic Disease

ArticleYear
Clinical and immunological features of chronic ulcerative stomatitis: A systematic review.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2022, Volume: 51, Issue:6

    Topics: Animals; Autoimmune Diseases; Chronic Disease; Female; Fluorescent Antibody Technique, Indirect; Gin

2022
Approach to Acute Cardiovascular Complications in COVID-19 Infection.
    Circulation. Heart failure, 2020, Volume: 13, Issue:7

    Topics: Acute Coronary Syndrome; Anti-Bacterial Agents; Antiviral Agents; Arrhythmias, Cardiac; Azithromycin

2020
Hydroxychloroquine Alternatives for Chronic Disease: Response to a Growing Shortage Amid the Global COVID-19 Pandemic.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:1

    Topics: Chronic Disease; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; SARS-CoV-2; United

2022
Hepatitis C virus-related arthritis.
    Autoimmunity reviews, 2008, Volume: 8, Issue:1

    Topics: Adrenal Cortex Hormones; Ankle; Antibodies, Viral; Arthralgia; Arthritis, Infectious; Arthritis, Rhe

2008
Chronic ulcerative stomatitis: a distinct clinical entity?
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2011, Volume: 66, Issue:3

    Topics: Adult; Antirheumatic Agents; Chronic Disease; Cyclosporine; Diagnosis, Differential; Female; Gingivi

2011
Chronic ulcerative stomatitis: diagnostic and management challenges--four new cases and review of literature.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 104, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Dermatologic Agents; Female; Fluorescent Antibody T

2007
Evaluation and therapy of chronic interstitial pneumonitis in children.
    Current opinion in pediatrics, 1994, Volume: 6, Issue:3

    Topics: Adrenal Cortex Hormones; Biopsy; Bronchoalveolar Lavage Fluid; Child; Chronic Disease; Clinical Prot

1994
Chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies.
    International journal of dermatology, 1996, Volume: 35, Issue:4

    Topics: Aged; Antibodies, Antinuclear; Antirheumatic Agents; Binding Sites, Antibody; Biomarkers; Biopsy; Ce

1996

Trials

10 trials available for hydroxychloroquine and Chronic Disease

ArticleYear
Hydroxychloroquine in the treatment of anti-histamine refractory chronic spontaneous urticaria, randomized single-blinded placebo-controlled trial and an open label comparison study.
    European annals of allergy and clinical immunology, 2017, Volume: 49, Issue:5

    Topics: Adult; Anti-Allergic Agents; Chronic Disease; Drug Resistance; Female; Histamine Antagonists; Humans

2017
Effect of prolonged antibiotic treatment on cognition in patients with Lyme borreliosis.
    Neurology, 2019, 03-26, Volume: 92, Issue:13

    Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Chronic Disease; Clarithromycin; Cognition; Double-Blind

2019
[Months of antibiotic therapy in persistent symptoms of Lyme disease without effect].
    Praxis, 2016, Jun-08, Volume: 105, Issue:12

    Topics: Anti-Bacterial Agents; Chronic Disease; Clarithromycin; Dose-Response Relationship, Drug; Doxycyclin

2016
Efficacy of combination DMARD therapy vs. hydroxychloroquine monotherapy in chronic persistent chikungunya arthritis: a 24-week randomized controlled open label study.
    Clinical rheumatology, 2017, Volume: 36, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Infectious; Chikungunya Fever; Chronic Disease; Female; Humans; Hyd

2017
Anti-CD13 Abs in children with extensive chronic GVHD and their relation to soluble CD13 after allogeneic blood and marrow transplantation from a Children's Oncology Groups Study, ASCT0031.
    Bone marrow transplantation, 2010, Volume: 45, Issue:11

    Topics: Adolescent; Antibodies; Biomarkers; Bone Marrow Transplantation; CD13 Antigens; Child; Child, Presch

2010
Early and late extensive chronic graft-versus-host disease in children is characterized by different Th1/Th2 cytokine profiles: findings of the Children's Oncology Group Study ASCT0031.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:12

    Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Cytokines; Double-Blind Method; Female;

2011
Randomized trial of hydroxychloroquine for newly diagnosed chronic graft-versus-host disease in children: a Children's Oncology Group study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Double-Blind Method; Female; Graft vs H

2012
Impact of hydroxychloroquine therapy on chronic urticaria: chronic autoimmune urticaria study and evaluation.
    Internal medicine journal, 2004, Volume: 34, Issue:4

    Topics: Adult; Autoimmune Diseases; Chronic Disease; Dermatologic Agents; Female; Humans; Hydroxychloroquine

2004
A randomized double-blind trial of hydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2007, Volume: 13, Issue:10

    Topics: Adult; Chronic Disease; Disease-Free Survival; Double-Blind Method; Female; Graft vs Host Disease; H

2007
Hydroxychloroquine for the treatment of chronic graft-versus-host disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:3A

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Ch

2000

Other Studies

47 other studies available for hydroxychloroquine and Chronic Disease

ArticleYear
Impaired adrenal cortex reserve in patients with rheumatic and musculoskeletal diseases who relapse upon tapering of low glucocorticoid dose.
    Clinical and experimental rheumatology, 2022, Volume: 40, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Insufficiency; Antirheumatic Agents; Arthritis, Rhe

2022
Effectiveness of Hydroxychloroquine and Omalizumab in Chronic Spontaneous Urticaria: A Real-World Study.
    The journal of allergy and clinical immunology. In practice, 2022, Volume: 10, Issue:12

    Topics: Anti-Allergic Agents; Chronic Disease; Chronic Urticaria; Humans; Hydroxychloroquine; Omalizumab; Re

2022
Does hydroxychloroquine work for chronic spontaneous urticaria?
    The journal of allergy and clinical immunology. In practice, 2023, Volume: 11, Issue:6

    Topics: Chronic Disease; Chronic Urticaria; Humans; Hydroxychloroquine; Urticaria

2023
Can hydroxychloroquine be useful in the prevention of COVID-19? An Italian survey in dermatologic and rheumatologic patients already under treatment.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:1

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Betacoronavirus; Chronic Disease; Coronavirus Infect

2020
Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:6

    Topics: Chronic Disease; COVID-19; Glucocorticoids; Humans; Hydroxychloroquine; Recurrence; Sarcoidosis

2021
Novel combination therapy of hydroxychloroquine and topical tacrolimus for chronic ulcerative stomatitis.
    International journal of dermatology, 2021, Volume: 60, Issue:4

    Topics: Administration, Topical; Chronic Disease; Combined Modality Therapy; Humans; Hydroxychloroquine; Imm

2021
Clinical characteristics of and outcomes for patients with COVID-19 and comorbid lung diseases primarily hospitalized in a conventional pulmonology unit: A retrospective study.
    Respiratory medicine and research, 2021, Volume: 79

    Topics: Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiviral Agents; Ch

2021
[Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine].
    Medicina clinica, 2021, 02-26, Volume: 156, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Chronic Disease; COVID-

2021
Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation.
    The Journal of pediatrics, 2021, Volume: 231

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chronic Disease; Female; Humans; Hydroxychloroqui

2021
Treatment of Chronic Q Fever: Clinical Efficacy and Toxicity of Antibiotic Regimens.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 02-10, Volume: 66, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Chronic Disease; Coxiella burnetii; Drug Therapy, Combination; Female;

2018
Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 120, Issue:1

    Topics: Acetates; Anti-Inflammatory Agents; Antimalarials; Cetirizine; Chronic Disease; Cyclopropanes; Diphe

2018
Patients With Arthralgia and Anti-Citrullinated Peptide Antibody Positivity on Hydroxychloroquine Therapy: An Update on 2 and 3 Years' Follow-up Data of a Pilot Study.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:7

    Topics: Adult; Aged; Anti-Citrullinated Protein Antibodies; Arthralgia; Arthritis, Rheumatoid; Chronic Disea

2019
Chronic hydroxychloroquine/chloroquine exposure for connective tissue diseases and risk of Alzheimer's disease: a population-based cohort study.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:2

    Topics: Alzheimer Disease; Antirheumatic Agents; Chloroquine; Chronic Disease; Connective Tissue Diseases; D

2019
Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects.
    The British journal of ophthalmology, 2019, Volume: 103, Issue:11

    Topics: Adult; Aged; Antirheumatic Agents; Chronic Disease; Early Diagnosis; Electroretinography; Female; Hu

2019
Q Fever in Southern California: a Case Series of 20 Patients from a VA Medical Center.
    The American journal of tropical medicine and hygiene, 2019, Volume: 101, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; California; Chronic Disease; Doxycycline; Endocarditis, Bacteria

2019
Retinal toxicity of high-dose hydroxychloroquine in patients with chronic graft-versus-host disease.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2015, Volume: 50, Issue:6

    Topics: Adult; Aged; Antimalarials; Chronic Disease; Color Vision Defects; Electroretinography; Female; Graf

2015
Drugs used in incident systemic lupus erythematosus - results from the Finnish nationwide register 2000-2007.
    Lupus, 2016, Volume: 25, Issue:6

    Topics: Adult; Aged; Antirheumatic Agents; Azathioprine; Chronic Disease; Female; Finland; Humans; Hydroxych

2016
The effect of increasing the dose of hydroxychloroquine (HCQ) in patients with refractory cutaneous lupus erythematosus (CLE): An open-label prospective pilot study.
    Journal of the American Academy of Dermatology, 2016, Volume: 74, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antimalarials; Chronic Disease; Dose-Response Relationship, Drug;

2016
Chronic ulcerative stomatitis.
    Oral diseases, 2008, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Diagnosis, Differential; Female; Gingivitis, Nec

2008
Chikungunya virus aches and pains: an emerging challenge.
    Arthritis and rheumatism, 2008, Volume: 58, Issue:9

    Topics: Alphavirus Infections; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chikungunya vi

2008
Familial chilblain lupus--a monogenic form of cutaneous lupus erythematosus due to a heterozygous mutation in TREX1.
    Dermatology (Basel, Switzerland), 2009, Volume: 219, Issue:2

    Topics: Adolescent; Aspirin; Biopsy, Needle; Chronic Disease; Disease Progression; Drug Therapy, Combination

2009
Selective thinning of the perifoveal inner retina as an early sign of hydroxychloroquine retinal toxicity.
    Eye (London, England), 2010, Volume: 24, Issue:5

    Topics: Adult; Aged; Antimalarials; Antirheumatic Agents; Chronic Disease; Female; Humans; Hydroxychloroquin

2010
A case of lupus erythematosus panniculitis presenting as combined linear and lipoatrophic skin lesions.
    International journal of dermatology, 2011, Volume: 50, Issue:2

    Topics: Adult; Antibodies, Antinuclear; Antimalarials; Chronic Disease; Female; Humans; Hydroxychloroquine;

2011
Post-chikungunya chronic arthritis--our experience with DMARDs over two year follow up.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Adult; Aged; Alphavirus Infections; Antirheumatic Agents; Arthritis, Rheumatoid; Chikungunya Fever;

2011
[Do combinations with hydroxychloroquine help?].
    MMW Fortschritte der Medizin, 2012, Nov-01, Volume: 154, Issue:19

    Topics: Anti-Bacterial Agents; Antimalarials; Chronic Disease; Doxycycline; Drug Therapy, Combination; Human

2012
Chronic ulcerative stomatitis: clinical, histopathologic, and immunopathologic findings.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2003, Volume: 96, Issue:6

    Topics: Adult; Aged; Antibodies, Antinuclear; Blotting, Western; Cell Nucleus; Chronic Disease; Diagnosis, D

2003
Chronic Lyme borreliosis at the root of multiple sclerosis--is a cure with antibiotics attainable?
    Medical hypotheses, 2005, Volume: 64, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Borrelia burgdorferi Group; Chronic Disease; Drug Therapy, Combinati

2005
Hydroxychloroquine causes severe vacuolar myopathy in a patient with chronic graft-versus-host disease.
    American journal of hematology, 2005, Volume: 78, Issue:4

    Topics: Biopsy; Bone Marrow Transplantation; Chronic Disease; Enzyme Inhibitors; Graft vs Host Disease; Huma

2005
Discoid lupus erythematosus masquerading as chronic blepharoconjunctivitis.
    Ophthalmology, 2005, Volume: 112, Issue:5

    Topics: Adult; Antirheumatic Agents; Blepharitis; Chronic Disease; Conjunctivitis; Diagnosis, Differential;

2005
Chronic inflammation of the vagina: treatment and relationship to autoimmunity.
    The Journal of reproductive medicine, 2005, Volume: 50, Issue:7

    Topics: Adolescent; Adult; Antirheumatic Agents; Autoimmune Diseases; Chronic Disease; Dyspareunia; Endometr

2005
The value of follow-up after acute Q fever infection.
    The Journal of infection, 2006, Volume: 52, Issue:4

    Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Chronic Disease; Complement Fixation Tests; Coxiella b

2006
Muscle involvement in sarcoidosis: a retrospective and followup studies.
    The Journal of rheumatology, 2006, Volume: 33, Issue:1

    Topics: Adult; Cardiomyopathies; Chronic Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studie

2006
[Chronic oligoarthritis in children].
    Revue du rhumatisme et des maladies osteo-articulaires, 1967, Volume: 34, Issue:9

    Topics: Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Glucocorticoids; Humans; Hydr

1967
Chronic cutaneous lupus erythematosus. Clinical, laboratory, therapeutic, and prognostic examination of 62 patients.
    Archives of dermatology, 1982, Volume: 118, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Blood Sedimentation; Chronic Disease; Female; Huma

1982
Systemic lupus erythematosus: important considerations in the adolescent.
    Journal of adolescent health care : official publication of the Society for Adolescent Medicine, 1982, Volume: 2, Issue:4

    Topics: Adolescent; Alopecia; Anxiety; Chronic Disease; Depression; Female; Humans; Hydroxychloroquine; Lupu

1982
Treatment of chronic Lyme arthritis with hydroxychloroquine.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:12

    Topics: Adult; Arthritis, Infectious; Chronic Disease; Humans; Hydroxychloroquine; Knee Joint; Male; Radiogr

1981
Hydroxychloroquine in the treatment of chronic erythema nodosum.
    The British journal of dermatology, 1995, Volume: 132, Issue:4

    Topics: Adult; Chronic Disease; Erythema Nodosum; Female; Humans; Hydroxychloroquine

1995
Hydroxychloroquine and chronic erythema nodosum.
    The British journal of dermatology, 1996, Volume: 134, Issue:2

    Topics: Chronic Disease; Dermatologic Agents; Erythema Nodosum; Female; Humans; Hydroxychloroquine; Middle A

1996
Long-term management of hypercalcaemia in chronically active sarcoidosis.
    Journal of the Royal Society of Medicine, 1997, Volume: 90, Issue:3

    Topics: Adult; Chronic Disease; Diphosphonates; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Hy

1997
Chronic ulcerative stomatitis.
    The British journal of dermatology, 1997, Volume: 137, Issue:2

    Topics: Adult; Chronic Disease; Female; Fluorescent Antibody Technique, Direct; Fluorescent Antibody Techniq

1997
Hypertrophic discoid lupus erythematosus of the conjunctiva.
    American journal of ophthalmology, 1999, Volume: 127, Issue:5

    Topics: Biopsy; Blepharitis; Chronic Disease; Conjunctiva; Conjunctivitis; Female; Humans; Hydroxychloroquin

1999
Acral keratotic graft versus host disease simulating warts.
    The Australasian journal of dermatology, 1999, Volume: 40, Issue:3

    Topics: Bone Marrow Transplantation; Chronic Disease; Diagnosis, Differential; Graft vs Host Disease; Humans

1999
Treatment of chronic GVHD.
    Bone marrow transplantation, 2000, Volume: 26, Issue:4

    Topics: Chronic Disease; Graft vs Host Disease; Humans; Hydroxychloroquine; Randomized Controlled Trials as

2000
Ten cases of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibody.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:5 Pt 1

    Topics: Adult; Aged; Antibodies, Antinuclear; Chronic Disease; Female; Fluorescent Antibody Technique; Gingi

1991
Clinical, serologic and immunogenetic studies in patients with chronic cutaneous (discoid) lupus erythematosus who have verrucous and/or hypertrophic skin lesions.
    The Journal of rheumatology, 1988, Volume: 15, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Antibodies, Antinuclear; Chronic Disease; DNA, Single-Stranded; Fema

1988
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
    La Clinica terapeutica, 1972, Aug-15, Volume: 62, Issue:3

    Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gol

1972
[Treatment of chronic discoid lupus erythematosus with triamcinolone acetonide using the occlusive dressing technic].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1970, Volume: 21, Issue:10

    Topics: Adult; Aged; Chronic Disease; Cosmetics; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; M

1970