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hydroxychloroquine and Cell Transformation, Neoplastic

hydroxychloroquine has been researched along with Cell Transformation, Neoplastic in 5 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atzori, L1
Robustelli Test, E1
Ferreli, C1
Pilloni, L1
Rongioletti, F1
Parkhitko, AA1
Priolo, C1
Coloff, JL1
Yun, J1
Wu, JJ1
Mizumura, K1
Xu, W1
Malinowska, IA1
Yu, J1
Kwiatkowski, DJ1
Locasale, JW1
Asara, JM1
Choi, AM1
Finkel, T1
Henske, EP1
Chen, N1
Eritja, N1
Lock, R1
Debnath, J1
Xie, X1
White, EP1
Mehnert, JM1
Gupta, U1
Barman, KD1
Saify, K1

Other Studies

5 other studies available for hydroxychloroquine and Cell Transformation, Neoplastic

ArticleYear
Impressive oral lichen planus progression to invasive squamous cell carcinoma in a three months lapse.
    Oral oncology, 2019, Volume: 90

    Topics: Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cicatrix; Disease Progression; Follow-Up

2019
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:1

    Topics: 6-Aminonicotinamide; Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5;

2014
Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture.
    Oncogene, 2013, May-16, Volume: 32, Issue:20

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Autophagy; Cell Culture Techniques; Cell Line; Cell

2013
Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Allosteric Regulation; Animals; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Proli

2013
Squamous cell carcinoma complicating an untreated chronic discoid lupus erythematosus (CDLE) lesion in a black female.
    The Journal of dermatology, 2005, Volume: 32, Issue:12

    Topics: Adult; Biopsy, Needle; Black People; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Comb

2005