Page last updated: 2024-10-28

hydroxychloroquine and Cardiovascular Pregnancy Complications

hydroxychloroquine has been researched along with Cardiovascular Pregnancy Complications in 8 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy."1.56Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020)
"Thus, the pregnancy was considered a high-risk pregnancy."1.42[Systemic lupus erythematosus and a medical history of deep vein thrombosis in a 27-year-old pregnant woman]. ( Puppe, V, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Juusela, A1
Nazir, M1
Gimovsky, M1
Breslin, N1
Baptiste, C1
Miller, R1
Fuchs, K1
Goffman, D1
Gyamfi-Bannerman, C1
D'Alton, M1
Ortiz Molina, E1
Hernandez Pailos, R1
Pola Guillen, M1
Pascual Pedreno, A1
Rodriguez Rodriguez, E1
Hernandez Martinez, A1
Gan, SP1
Ong, SG1
Puppe, V1
Merashli, M1
Noureldine, MH1
Uthman, I1
Khamashta, M1
Chaturvedi, S1
McCrae, KR1
Izmirly, PM1
Costedoat-Chalumeau, N1
Pisoni, CN1
Khamashta, MA1
Kim, MY1
Saxena, A1
Friedman, D1
Llanos, C1
Piette, JC1
Buyon, JP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Trial Evaluating Effect of Outpatient Hydroxychloroquine on Reducing Hospital Admissions in Pregnant Women With SARS-CoV-2 Infection: HyPreC Trial[NCT04354441]Phase 20 participants (Actual)Interventional2020-05-31Withdrawn (stopped due to Not started)
Home Monitoring of Fetal Heart Rhythm in Pregnancies of Anti-Ro/SSA Positive Women for the Treatment of Congenital Heart Block (FETAL HOPE)[NCT05958446]200 participants (Anticipated)Observational2022-04-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydroxychloroquine and Cardiovascular Pregnancy Complications

ArticleYear
Antiphospholipid syndrome: an update.
    European journal of clinical investigation, 2015, Volume: 45, Issue:6

    Topics: Adrenal Cortex Hormones; Animals; Annexin A2; Anticoagulants; Antiphospholipid Syndrome; Drugs, Inve

2015
The antiphospholipid syndrome: still an enigma.
    Hematology. American Society of Hematology. Education Program, 2015, Volume: 2015

    Topics: Administration, Oral; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; beta

2015

Other Studies

6 other studies available for hydroxychloroquine and Cardiovascular Pregnancy Complications

ArticleYear
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi

2020
Coronavirus disease 2019 in pregnancy: early lessons.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi

2020
COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis.
    Ginekologia polska, 2020, Volume: 91, Issue:12

    Topics: Adult; Anosmia; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; C-Reactive Protein; Cesarea

2020
Antithrombotic effects of hydroxychloroquine in a pregnant patient with Antiphospholipid syndrome and recurrent venous thromboembolism.
    The Medical journal of Malaysia, 2017, Volume: 72, Issue:2

    Topics: Antiphospholipid Syndrome; Antithrombins; Female; Humans; Hydroxychloroquine; Pregnancy; Pregnancy C

2017
[Systemic lupus erythematosus and a medical history of deep vein thrombosis in a 27-year-old pregnant woman].
    Der Internist, 2015, Volume: 56, Issue:3

    Topics: Adult; Antirheumatic Agents; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Hyd

2015
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.
    Circulation, 2012, Jul-03, Volume: 126, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Cohort Studies; Databases, Factual; Female; France; Humans; Hydroxyc

2012
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.
    Circulation, 2012, Jul-03, Volume: 126, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Cohort Studies; Databases, Factual; Female; France; Humans; Hydroxyc

2012
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.
    Circulation, 2012, Jul-03, Volume: 126, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Cohort Studies; Databases, Factual; Female; France; Humans; Hydroxyc

2012
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.
    Circulation, 2012, Jul-03, Volume: 126, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Cohort Studies; Databases, Factual; Female; France; Humans; Hydroxyc

2012