hydroxychloroquine has been researched along with Cardiomegaly in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Danon disease is a lethal X-linked genetic syndrome resulting from radical mutations in the LAMP2 gene." | 1.72 | Autophagy guided interventions to modify the cardiac phenotype of Danon disease. ( Abraham, NG; Alcalai, R; Arad, M; Hochhauser, E; Petrover, Z; Seidman, CE; Seidman, J; Shainberg, A; Waldman, M; Yadin, D, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Homme, RP | 1 |
| George, AK | 1 |
| Singh, M | 1 |
| Smolenkova, I | 1 |
| Zheng, Y | 1 |
| Pushpakumar, S | 1 |
| Tyagi, SC | 1 |
| Yadin, D | 1 |
| Petrover, Z | 1 |
| Shainberg, A | 1 |
| Alcalai, R | 1 |
| Waldman, M | 1 |
| Seidman, J | 1 |
| Seidman, CE | 1 |
| Abraham, NG | 1 |
| Hochhauser, E | 1 |
| Arad, M | 1 |
2 other studies available for hydroxychloroquine and Cardiomegaly
| Article | Year |
|---|---|
Mechanism of Blood-Heart-Barrier Leakage: Implications for COVID-19 Induced Cardiovascular Injury.
Topics: Animals; Blood; Blood Physiological Phenomena; Cardiomegaly; Cardiovascular Diseases; Cardiovascular | 2021 |
Autophagy guided interventions to modify the cardiac phenotype of Danon disease.
Topics: Animals; Autophagy; Bortezomib; Cardiomegaly; Cardiomyopathies; Glycogen Storage Disease Type IIb; H | 2022 |