hydroxychloroquine has been researched along with Cafe-au-Lait Spots with Pulmonic Stenosis in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Excerpt | Relevance | Reference |
---|---|---|
"Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene." | 5.62 | Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine. ( Furue, M; Kato, T; Takai-Yumine, A; Tsuji, G, 2021) |
"Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene." | 1.62 | Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine. ( Furue, M; Kato, T; Takai-Yumine, A; Tsuji, G, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 2 (100.00) | 2.80 |
Authors | Studies |
---|---|
Yumine, A | 1 |
Tsuji, G | 2 |
Takai-Yumine, A | 1 |
Kato, T | 1 |
Furue, M | 1 |
2 other studies available for hydroxychloroquine and Cafe-au-Lait Spots with Pulmonic Stenosis
Article | Year |
---|---|
Hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 Schwann cells.
Topics: Antimalarials; Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Collagen Type I, alpha 1 | 2021 |
Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine.
Topics: Antimalarials; Cells, Cultured; Chloroquine; Down-Regulation; Fibroblasts; Humans; Hydroxychloroquin | 2021 |