Page last updated: 2024-10-28

hydroxychloroquine and Blood Pressure, High

hydroxychloroquine has been researched along with Blood Pressure, High in 44 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"To investigate the therapeutic benefit of cyclosporin A (CSA) switching to hydroxychloroquine (HCQ) in patients with rheumatoid arthritis (RA)."9.09Treatment with cyclosporin switching to hydroxychloroquine in patients with rheumatoid arthritis. ( Cho, CS; Kim, HY; Kim, WU; Lee, SK; Lee, WK; Paek, SI; Park, SH; Seo, YI; Song, HH, 2001)
"We conclude that hydroxychloroquine alleviated hypertension, proteinuria, and normalized soluble fms-like kinase-1 and endothelin-1 levels in our preeclampsia model and that these changes may involve the restoration of endothelial dysfunction; thus, hydroxychloroquine could potentially be used for preventing preeclampsia, even in the absence of lupus."8.12Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model. ( Byun, N; Cho, GJ; Choi, M; Choi, SJ; Hwang, JR; Kim, JS; Oh, SY; Roh, CR; Seok, YS; Sung, JH, 2022)
"To investigate the therapeutic benefit of cyclosporin A (CSA) switching to hydroxychloroquine (HCQ) in patients with rheumatoid arthritis (RA)."5.09Treatment with cyclosporin switching to hydroxychloroquine in patients with rheumatoid arthritis. ( Cho, CS; Kim, HY; Kim, WU; Lee, SK; Lee, WK; Paek, SI; Park, SH; Seo, YI; Song, HH, 2001)
"We conclude that hydroxychloroquine alleviated hypertension, proteinuria, and normalized soluble fms-like kinase-1 and endothelin-1 levels in our preeclampsia model and that these changes may involve the restoration of endothelial dysfunction; thus, hydroxychloroquine could potentially be used for preventing preeclampsia, even in the absence of lupus."4.12Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model. ( Byun, N; Cho, GJ; Choi, M; Choi, SJ; Hwang, JR; Kim, JS; Oh, SY; Roh, CR; Seok, YS; Sung, JH, 2022)
"To investigate whether hydroxychloroquine treatment is associated with major adverse cardiovascular events (MACE) (myocardial infarction, ischemic stroke, or cardiovascular-associated death) in patients with cutaneous LE (CLE) or systemic LE (SLE)."4.02Use of hydroxychloroquine and risk of major adverse cardiovascular events in patients with lupus erythematosus: A Danish nationwide cohort study. ( Dreyer, L; Egeberg, A; Gislason, G; Haugaard, JH; Kofoed, K; Ottosen, MB, 2021)
"A 71-year old gentleman with history of arterial hypertension treated with valsartan presented on was hospitalized at the Infectious Diseases Unit, University of Bologna (Italy) for severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) and received treatment with hydroxychloroquine 200mg bid (400 mg bid the first day), azithromycin 400 mg qd, thrombotic prophylaxis with enoxaparin 4000 UI qd and Venturi mask oxygen delivering FiO2 of 31%."3.96Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin. ( Bartoletti, M; Viale, P, 2020)
" Patients treated with leflunomide had increases in BP and a greater risk of incident hypertension compared with patients treated with methotrexate (hazard ratio, 1."3.88Initiation of Disease-Modifying Therapies in Rheumatoid Arthritis Is Associated With Changes in Blood Pressure. ( Baker, JF; Cannella, A; Cannon, GW; Caplan, L; Davis, LA; England, BR; George, M; Ibrahim, S; Michaud, K; Mikuls, TR; OʼDell, J; Sauer, B; Teng, CC, 2018)
"To compare the risk of incident hypertension between initiators of tumor necrosis factor (TNF)-α inhibitors and initiators of nonbiologic disease modifying antirheumatic drugs (hereafter referred to as nonbiologics) in rheumatoid arthritis patients taking methotrexate monotherapy."3.83Tumor Necrosis Factor-α Inhibitor Use and the Risk of Incident Hypertension in Patients with Rheumatoid Arthritis. ( Danaei, G; Desai, RJ; Kim, SC; Liao, KP; Schneeweiss, S; Solomon, DH, 2016)
" Subcutaneous administration of methotrexate was more effective than the oral administration at the same dosage in patients suffering from active rheumatoid arthritis."3.74[What's new in internal medicine?]. ( Francès, C, 2008)
"Patients with systemic lupus erythematosus (SLE) have increased cardiovascular morbidity and mortality."2.77QT dispersion in patients with systemic lupus erythematosus: the impact of disease activity. ( Ghahartars, M; Kojuri, J; Liaghat, L; Mahmoody, Y; Nazarinia, MA; Rezaian, Gr, 2012)
"Hypertension and chronic obstructive pulmonary disease were also related to admission."1.62Biological markers and follow-up after discharge home of patients with COVID-19 pneumonia. ( Andrés, EM; Domínguez García, MJ; Gutiérrez Gabriel, S; Moreno García, N; Pérez Mañas, G; Silvan Domínguez, M, 2021)
"The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy."1.56Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020)
"Since December 2019, Coronavirus Disease 2019 (COVID-19) has emerged as a global pandemic."1.56Proinflammatory cytokines are associated with prolonged viral RNA shedding in COVID-19 patients. ( Gao, C; Jin, CC; Tong, YX; Xiao, AT; Zhang, S; Zhu, L, 2020)
"Hydroxychloroquine was associated with significantly lower BPV."1.56Blood Pressure Variability and Age-related Blood Pressure Patterns in Systemic Lupus Erythematosus. ( Magder, LS; Petri, M; Stojan, G, 2020)
"Childhood-onset systemic lupus erythematosus (SLE) is a severe, lifelong, multisystem autoimmune disease."1.51Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus. ( Bijl, M; Bultink, IEM; de Leeuw, K; Dolhain, RJEM; Fritsch-Stork, R; Groot, N; Kamphuis, S; Shaikhani, D; Teng, YKO; Zirkzee, E, 2019)
"We hypothesized that patients with systemic lupus erythematosus (SLE) have greater blood pressure visit-to-visit variability than control subjects and that blood pressure visit-to-visit variability is associated with a higher comorbidity burden."1.51Increased blood pressure visit-to-visit variability in patients with systemic lupus erythematosus: association with inflammation and comorbidity burden. ( Barker, KA; Barnado, A; Chung, CP; Dickson, AL; Dupont, WD; Gandelman, JS; Khan, OA; Neal, JE; Reese, T; Shuey, MM; Stein, CM, 2019)
"Hydroxychloroquine was the most frequently filled DMARD (13."1.46End-stage renal disease in patients with rheumatoid arthritis. ( Bethel, M; Brown, S; Carbone, L; Chen, CC; Nahman, NS; Paudyal, S; Rice, C; Skelton, M; Yang, FM, 2017)
"Hydroxychloroquine-treated lupus patients showed a lower incidence of thromboembolic disease."1.40Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus. ( Algieri, F; Duarte, J; Gálvez, J; Gómez-Guzmán, M; Gómez-Morales, M; Jiménez, R; López-Farré, AJ; O'Valle, F; Pérez-Vizcaino, F; Romero, M; Sabio, JM; Sánchez, M; Zarzuelo, MJ, 2014)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.27)18.7374
1990's0 (0.00)18.2507
2000's5 (11.36)29.6817
2010's11 (25.00)24.3611
2020's27 (61.36)2.80

Authors

AuthorsStudies
García, RD1
Asensio, JA1
Perdicaro, DJ1
de Los Ángeles Peral, M1
Clemmer, JS1
Hillegass, WB1
Taylor, EB1
Fung, KW1
Baik, SH1
Baye, F1
Zheng, Z1
Huser, V1
McDonald, CJ1
Choi, M1
Hwang, JR1
Sung, JH1
Byun, N1
Seok, YS1
Cho, GJ1
Choi, SJ1
Kim, JS2
Oh, SY1
Roh, CR1
Corrêa, BSG1
de Barros, S1
Vaz, JB1
Peres, MA1
Uchiyama, MK1
da Silva, AA1
Furukawa, LNS1
Lipworth, B1
Chan, R1
Lipworth, S1
RuiWen Kuo, C1
Khaddour, K1
Sikora, A1
Tahir, N1
Nepomuceno, D1
Huang, T1
Dariya, B1
Nagaraju, GP1
Everaert, BR1
Muylle, J1
Bartholomeus Twickler, T1
Vicenzi, M1
Di Cosola, R1
Ruscica, M1
Ratti, A1
Rota, I1
Rota, F1
Bollati, V1
Aliberti, S1
Blasi, F1
Medetalibeyoğlu, A1
Şenkal, N1
Çapar, G1
Köse, M1
Tükek, T1
Breslin, N1
Baptiste, C1
Miller, R1
Fuchs, K1
Goffman, D1
Gyamfi-Bannerman, C1
D'Alton, M1
Viale, P1
Bartoletti, M1
Wang, Y1
Foo, R1
Thum, T1
Santos, CS1
Morales, CM1
Álvarez, ED1
Castro, CÁ1
Robles, AL1
Sandoval, TP1
Rein, N1
Haham, N1
Orenbuch-Harroch, E1
Romain, M1
Argov, Z1
Vaknin-Dembinsky, A1
Gotkine, M1
Choi, NH1
Silver, ES1
Fremed, M1
Liberman, L1
Patel, M1
Gangemi, A1
Marron, R1
Chowdhury, J1
Yousef, I1
Zheng, M1
Mills, N1
Tragesser, L1
Giurintano, J1
Gupta, R1
Gordon, M1
Rali, P1
D'Alonso, G1
Fleece, D1
Zhao, H1
Patlakh, N1
Criner, G1
García-Saavedra, MB1
Rosales-Gutiérrez, RR1
Valverde, E1
Chumbes-Aguirre, M1
Alvarado, R1
Polo, R1
Azañero, R1
Chávez, C1
Sobol, I1
Yuzefpolskaya, M1
Roth, Z1
Colombo, PC1
Horn, E1
Takeda, K1
Sayer, G1
Uriel, N1
Naka, Y1
Brusasco, C1
Corradi, F1
Di Domenico, A1
Raggi, F1
Timossi, G1
Santori, G1
Brusasco, V1
Gao, C1
Zhu, L1
Jin, CC1
Tong, YX1
Xiao, AT1
Zhang, S1
Riou, M1
Marcot, C1
Canuet, M1
Renaud-Picard, B1
Chatron, E1
Porzio, M1
Dégot, T1
Hirschi, S1
Metz-Favre, C1
Kassegne, L1
Ederle, C1
Khayath, N1
Labani, A1
Leyendecker, P1
De Blay, F1
Kessler, R1
Haugaard, JH1
Dreyer, L1
Ottosen, MB1
Gislason, G1
Kofoed, K1
Egeberg, A1
Lee, KH1
Hong, SH1
Seong, D1
Choi, YR1
Ahn, YT1
Kim, KS1
Kim, SE1
Lee, S1
Sim, W1
Kim, D1
Jun, B1
Yang, JW1
Yon, DK1
Lee, SW1
Kim, MS1
Dragioti, E1
Li, H1
Jacob, L1
Koyanagi, A1
Abou Ghayda, R1
Shin, JI1
Smith, L1
Gutiérrez Gabriel, S1
Domínguez García, MJ1
Pérez Mañas, G1
Moreno García, N1
Silvan Domínguez, M1
Andrés, EM1
Baker, JF1
Sauer, B1
Teng, CC1
George, M1
Cannon, GW1
Ibrahim, S1
Cannella, A1
England, BR1
Michaud, K1
Caplan, L1
Davis, LA1
OʼDell, J1
Mikuls, TR1
Groot, N1
Shaikhani, D1
Teng, YKO1
de Leeuw, K1
Bijl, M1
Dolhain, RJEM1
Zirkzee, E1
Fritsch-Stork, R1
Bultink, IEM1
Kamphuis, S1
DeParis, SW1
Joseph, SS1
Stojan, G1
Magder, LS1
Petri, M1
Reese, T1
Dickson, AL1
Shuey, MM1
Gandelman, JS1
Barnado, A1
Barker, KA1
Neal, JE1
Khan, OA1
Dupont, WD1
Stein, CM1
Chung, CP1
Ekwom, PE1
Gómez-Guzmán, M1
Jiménez, R1
Romero, M1
Sánchez, M1
Zarzuelo, MJ1
Gómez-Morales, M1
O'Valle, F1
López-Farré, AJ1
Algieri, F1
Gálvez, J1
Pérez-Vizcaino, F1
Sabio, JM1
Duarte, J1
Joo, YB1
Sung, YK1
Shim, JS1
Kim, JH1
Lee, EK1
Lee, HS1
Bae, SC1
Uutela, T1
Kautiainen, H1
Järvenpää, S1
Salomaa, S1
Hakala, M1
Häkkinen, A1
Desai, RJ1
Solomon, DH1
Schneeweiss, S1
Danaei, G1
Liao, KP1
Kim, SC1
Paudyal, S1
Yang, FM1
Rice, C1
Chen, CC1
Skelton, M1
Bethel, M1
Brown, S1
Nahman, NS1
Carbone, L1
Francès, C1
Kojuri, J1
Nazarinia, MA1
Ghahartars, M1
Mahmoody, Y1
Rezaian, Gr1
Liaghat, L1
McLaurin, EY1
Holliday, SL1
Williams, P1
Brey, RL1
Mittal, BV1
Pendse, S1
Rennke, HG1
Singh, AK1
Tanay, A1
Leibovitz, E1
Frayman, A1
Zimlichman, R1
Shargorodsky, M1
Gavish, D1
Kim, WU1
Seo, YI1
Park, SH1
Lee, WK1
Lee, SK1
Paek, SI1
Cho, CS1
Song, HH1
Kim, HY1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Secondary Event Prevention Using Population Risk Management After PCI[NCT02694185]5,269 participants (Actual)Interventional2016-10-01Active, not recruiting
QT Dispersion in Patients With Systemic Lupus Erythematosus: the Impact of Disease Activity[NCT01031797]124 participants (Actual)Observational2008-01-31Completed
Hydroxychloroquine Assessment of Management Study in Coronary Artery Disease After Angiography.[NCT02874287]Phase 435 participants (Actual)Interventional2017-10-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cardiovascular Events (CVE)

Cardiovascular Events (CVEs) such as mortality, myocardial infarction, stroke, or repeat revascularization among IHD patients at 12 months post-PCI and progressive erosive disease demonstrated in patients with rheumatic disease will be monitored. CVEs will be monitored to determine if there is a reduction in the occurrence of those events as a result of the intervention. (NCT02694185)
Timeframe: 1 year

InterventionCardiovascular events (Mean)
Experimental Group15.2
Control Group14.3

Incremental Cost Effectiveness (ICE)

To establish the cost to implement and maintain the intervention, above the cost of usual care. Incremental Cost Effectiveness (ICE) is the cost to achieve a 10% improvement in PDC, and the cost of CVE prevented. (NCT02694185)
Timeframe: through study completion, an average of 1 year

Interventiondollars per patient (Median)
Experimental Group821.45
Control Group893.55

Proportion of Days Covered (PDC)

Proportion of Days Covered (PDC) is measured by looking at the number of doses of medication a patient has versus days in the month (if a patient has 20 days of medication for a 30 day period their PDC is 20/30, 2/3, or 66.7%). Used to assess the effectiveness of the intervention, PDC will be tested among IHD patients in the year after PCI and among rheumatology clinic patients chronically prescribed DMARDs. (NCT02694185)
Timeframe: 1 year

,
Interventionpercentage of days covered (Mean)
Anti-plateletBeta-BlockerStatin
Control Group75.673.371.2
Experimental Group82.678.478.8

Reviews

4 reviews available for hydroxychloroquine and Blood Pressure, High

ArticleYear
The Role of Inflammation as a Preponderant Risk Factor in Cardiovascular Diseases.
    Current vascular pharmacology, 2022, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hydroxychloroqui

2022
Understanding novel COVID-19: Its impact on organ failure and risk assessment for diabetic and cancer patients.
    Cytokine & growth factor reviews, 2020, Volume: 53

    Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Betacoronavirus; Comorbid

2020
[Cardiovascular implications of SARS-CoV-2 infection: A literature review].
    Medwave, 2020, Aug-28, Volume: 20, Issue:7

    Topics: Acute Coronary Syndrome; Algorithms; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme

2020
Risk factors of COVID-19 mortality: a systematic review of current literature and lessons from recent retracted articles.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:24

    Topics: Age Factors; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Asian Peopl

2020

Trials

2 trials available for hydroxychloroquine and Blood Pressure, High

ArticleYear
QT dispersion in patients with systemic lupus erythematosus: the impact of disease activity.
    BMC cardiovascular disorders, 2012, Feb-27, Volume: 12

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Echocardiography; Electrocardiography; Fema

2012
Treatment with cyclosporin switching to hydroxychloroquine in patients with rheumatoid arthritis.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Female; Humans; Hydroxychloroquine

2001

Other Studies

38 other studies available for hydroxychloroquine and Blood Pressure, High

ArticleYear
Antihypertensive effects of immunosuppressive therapy in autoimmune disease.
    Journal of human hypertension, 2023, Volume: 37, Issue:4

    Topics: Antihypertensive Agents; Female; Humans; Hydroxychloroquine; Hypertension; Immunosuppression Therapy

2023
Effect of common maintenance drugs on the risk and severity of COVID-19 in elderly patients.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; COVID-19 Drug Trea

2022
Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model.
    Journal of hypertension, 2022, 12-01, Volume: 40, Issue:12

    Topics: Animals; Blood Pressure; Endothelial Cells; Endothelin-1; Female; Hydroxychloroquine; Hypertension;

2022
COVID-19: Understanding the impact of anti-hypertensive drugs and hydroxychloroquine on the ACE1 and ACE2 in lung and adipose tissue in SHR and WKY rats.
    Physiological reports, 2023, Volume: 11, Issue:3

    Topics: Adipose Tissue; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; C

2023
Weathering the Cytokine Storm in Susceptible Patients with Severe SARS-CoV-2 Infection.
    The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Angiotensin-Converting Enzyme Inhi

2020
Case Report: The Importance of Novel Coronavirus Disease (COVID-19) and Coinfection with Other Respiratory Pathogens in the Current Pandemic.
    The American journal of tropical medicine and hygiene, 2020, Volume: 102, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Azithromycin; Betacoronavirus; Ceftriaxone; Chicago; Chronic Pain

2020
Emerging cardiological issues during the COVID-19 pandemic.
    European journal of clinical investigation, 2020, Volume: 50, Issue:7

    Topics: Antiviral Agents; Arrhythmias, Cardiac; Betacoronavirus; Coronary Artery Disease; Coronavirus Infect

2020
The liaison between respiratory failure and high blood pressure: evidence from COVID-19 patients.
    The European respiratory journal, 2020, Volume: 56, Issue:1

    Topics: Aged; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Disease Progressio

2020
Characteristics of the initial patients hospitalized for COVID-19: a single-center report
    Turkish journal of medical sciences, 2020, Aug-26, Volume: 50, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhi

2020
Coronavirus disease 2019 in pregnancy: early lessons.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi

2020
Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin.
    Le infezioni in medicina, 2020, Jun-01, Volume: 28, Issue:suppl 1

    Topics: Aged; Anti-Inflammatory Agents; Anticoagulants; Antihypertensive Agents; Azithromycin; Combined Moda

2020
Using "old" medications to fight new COVID-19: Re-purposing with a purpose.
    Journal of molecular and cellular cardiology, 2020, Volume: 146

    Topics: Adenosine Monophosphate; Alanine; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Betaco

2020
Determinants of COVID-19 disease severity in patients with underlying rheumatic disease.
    Clinical rheumatology, 2020, Volume: 39, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiv

2020
Description of 3 patients with myasthenia gravis and COVID-19.
    Journal of the neurological sciences, 2020, 10-15, Volume: 417

    Topics: Adult; Aged; Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatmen

2020
COVID-19 reveals Brugada pattern in an adolescent patient.
    Cardiology in the young, 2020, Volume: 30, Issue:11

    Topics: Antiviral Agents; Brugada Syndrome; C-Reactive Protein; Chest Pain; Consanguinity; Cough; COVID-19;

2020
Retrospective analysis of high flow nasal therapy in COVID-19-related moderate-to-severe hypoxaemic respiratory failure.
    BMJ open respiratory research, 2020, Volume: 7, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antirheumat

2020
Characteristics and Outcomes of Patients With a Left Ventricular Assist Device With Coronavirus Disease-19.
    Journal of cardiac failure, 2020, Volume: 26, Issue:10

    Topics: Adult; Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Diabetes Mellitus; F

2020
Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure.
    The European respiratory journal, 2021, Volume: 57, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Air Filters; Algorithms; Antibodies, Monoclonal, Humanized; Antirheu

2021
Proinflammatory cytokines are associated with prolonged viral RNA shedding in COVID-19 patients.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 221

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; China; Comorbidity; COVID-19; COVID-19 Drug

2020
Clinical characteristics of and outcomes for patients with COVID-19 and comorbid lung diseases primarily hospitalized in a conventional pulmonology unit: A retrospective study.
    Respiratory medicine and research, 2021, Volume: 79

    Topics: Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiviral Agents; Ch

2021
Use of hydroxychloroquine and risk of major adverse cardiovascular events in patients with lupus erythematosus: A Danish nationwide cohort study.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:4

    Topics: Adult; Brain Ischemia; Cardiovascular Diseases; Cohort Studies; Comorbidity; Confounding Factors, Ep

2021
Biological markers and follow-up after discharge home of patients with COVID-19 pneumonia.
    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 2021, Volume: 33, Issue:3

    Topics: Adult; Aged; Antiviral Agents; Biomarkers; Comorbidity; COVID-19; COVID-19 Drug Treatment; Creatine

2021
Initiation of Disease-Modifying Therapies in Rheumatoid Arthritis Is Associated With Changes in Blood Pressure.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2018, Volume: 24, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Pressure; Female;

2018
Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus.
    Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aged; Antibodies, Antiphospholipid; Antirheumatic Agents; Child; Ch

2019
Bilateral Sequential Acute Proptosis in a Woman With No History of Trauma.
    JAMA ophthalmology, 2019, Feb-01, Volume: 137, Issue:2

    Topics: Acute Disease; Adult; Antirheumatic Agents; Drug Therapy, Combination; Enzyme Inhibitors; Exophthalm

2019
Blood Pressure Variability and Age-related Blood Pressure Patterns in Systemic Lupus Erythematosus.
    The Journal of rheumatology, 2020, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Antirheumatic Agents; Baltimore; Black or African Ameri

2020
Increased blood pressure visit-to-visit variability in patients with systemic lupus erythematosus: association with inflammation and comorbidity burden.
    Lupus, 2019, Volume: 28, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Blood Pressure; Case-Control Studies; Comorbidity; Cyclophosphamide;

2019
Systemic lupus erythematosus (SLE) at the Kenyatta National Hospital.
    Clinical rheumatology, 2013, Volume: 32, Issue:8

    Topics: Adolescent; Adult; Antibodies, Antinuclear; Arthritis; Black People; Child; Data Collection; Diabete

2013
Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme

2014
Prevalence, incidence, and associated factors of avascular necrosis in Korean patients with systemic lupus erythematosus: a nationwide epidemiologic study.
    Rheumatology international, 2015, Volume: 35, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Cohort Studies; Comorbidity; Databases,

2015
Patients with rheumatoid arthritis have better functional and working ability but poorer general health and higher comorbidity rates today than in the late 1990s.
    Scandinavian journal of rheumatology, 2015, Volume: 44, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Produc

2015
Tumor Necrosis Factor-α Inhibitor Use and the Risk of Incident Hypertension in Patients with Rheumatoid Arthritis.
    Epidemiology (Cambridge, Mass.), 2016, Volume: 27, Issue:3

    Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine

2016
End-stage renal disease in patients with rheumatoid arthritis.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Adalimumab; Adolescent; Adult; Amyloidosis; Antirheumatic Agents; Arthritis, Rheumatoid; Biological

2017
[What's new in internal medicine?].
    Annales de dermatologie et de venereologie, 2008, Volume: 135 Suppl 7

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Bacteriophages; Body Mass

2008
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant

2005
Hematuria in a patient with class IV lupus nephritis.
    Kidney international, 2006, Volume: 70, Issue:6

    Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerula

2006
Vascular elasticity of systemic lupus erythematosus patients is associated with steroids and hydroxychloroquine treatment.
    Annals of the New York Academy of Sciences, 2007, Volume: 1108

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arteries; Diabetes Mellitus; Elasticity; Female; Huma

2007
[Corticotherapy in rheumatoid polyarthritis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1971, Volume: 38, Issue:11

    Topics: Adrenocorticotropic Hormone; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Betamethasone; C

1971