hydroxychloroquine has been researched along with Arthritis, Juvenile in 44 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Arthritis, Juvenile: Arthritis in children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rare case of childhood pulmonary haemosiderosis with juvenile idiopathic arthritis is discussed, with particular reference to treatment with hydroxychloroquine and sildenafil for pulmonary hypertension which occurs secondary to this disease." | 3.74 | Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child. ( Noor, AS; Quah, BS; Rasool, AH; Roberton, D; Wong, AR, 2007) |
| "Juvenile idiopathic arthritis is the most frequent chronic rheumatic disease in childhood." | 2.53 | The role of synthetic drugs in the biologic era: therapeutic strategies for treating juvenile idiopathic arthritis. ( Horneff, G; Hügle, B, 2016) |
| "New information on the treatment of juvenile rheumatoid arthritis emphasizes more aggressive control of arthritis, particularly the use of methotrexate, both in low- and higher-dose regimens." | 2.38 | Treatment of juvenile rheumatoid arthritis. ( Emery, HM, 1993) |
| "The goals of pharmacotherapy in juvenile rheumatoid arthritis (JRA) are to suppress chronic synovitis which causes potential cartilage destruction and deformities, to control the systemic effects of inflammation (including growth retardation and nutritional deficits), relieve pain and limit psychological impact of disease." | 2.38 | Pharmacological management of juvenile rheumatoid arthritis. ( Doughty, RA; Rose, CD, 1992) |
| "Oral prednisone was used in 17 (81%) cases." | 1.91 | Childhood-onset rheumatoid arthritis at a tertiary hospital in Senegal, West Africa. ( Deme, A; Lissimo, H; Sabounji, MM, 2023) |
| "To evaluate the susceptibility to coronavirus disease 2019 (COVID-19) in patients with autoimmune conditions treated with antimalarials in a population-based study." | 1.62 | Susceptibility to COVID-19 in Patients Treated With Antimalarials: A Population-Based Study in Emilia-Romagna, Northern Italy. ( Bajocchi, G; Boiardi, L; Carrozzi, G; Cassone, G; Costantini, M; Croci, S; Galli, E; Giorgi Rossi, P; Gradellini, F; Mancuso, P; Marata, AM; Muratore, F; Pandolfi, P; Pipitone, N; Reta, M; Salvarani, C; Sandri, G; Viani, N, 2021) |
| "Aspirin remains the cornerstone of treatment for juvenile arthritis, although tolmetin may be more effective in controlling the fever of systemic-onset disease." | 1.27 | Treatment of juvenile arthritis. ( Baum, J, 1983) |
| "Children suffering from juvenile chronic arthritis need a longterm therapy and guidance for many years, in course of which drug therapy is only one part of the whole treatment regimen." | 1.27 | [Drug therapy of chronic juvenile arthritis]. ( Tulzer, W, 1987) |
| "The characteristics of juvenile rheumatoid arthritis have been presented and the important features of its medical and orthopedic management described." | 1.25 | Characteristics of juvenile rheumatoid arthritis: its medical and orthopedic management. ( Barry, PE; Stillman, JS, 1975) |
| "Surgical treatment of cataracts, band keratopathy, and glaucoma achieved uniformly discouraging results." | 1.25 | Ocular manifestations of juvenile rheumatoid arthritis. ( Bellows, AR; Bienfang, DC; Chylack, LT; Stillman, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (54.55) | 18.7374 |
| 1990's | 10 (22.73) | 18.2507 |
| 2000's | 2 (4.55) | 29.6817 |
| 2010's | 5 (11.36) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Sabounji, MM | 1 |
| Lissimo, H | 1 |
| Deme, A | 1 |
| Tarkiainen, M | 2 |
| Tynjälä, P | 2 |
| Vähäsalo, P | 2 |
| Kröger, L | 2 |
| Aalto, K | 2 |
| Lahdenne, P | 2 |
| Licciardi, F | 1 |
| Giani, T | 1 |
| Baldini, L | 1 |
| Favalli, EG | 1 |
| Caporali, R | 1 |
| Cimaz, R | 1 |
| Salvarani, C | 1 |
| Mancuso, P | 1 |
| Gradellini, F | 1 |
| Viani, N | 1 |
| Pandolfi, P | 1 |
| Reta, M | 1 |
| Carrozzi, G | 1 |
| Sandri, G | 1 |
| Bajocchi, G | 1 |
| Galli, E | 1 |
| Muratore, F | 1 |
| Boiardi, L | 1 |
| Pipitone, N | 1 |
| Cassone, G | 1 |
| Croci, S | 1 |
| Marata, AM | 1 |
| Costantini, M | 1 |
| Giorgi Rossi, P | 1 |
| Abdel, MP | 1 |
| Figgie, MP | 1 |
| Hügle, B | 1 |
| Horneff, G | 1 |
| Wong, AR | 1 |
| Noor, AS | 1 |
| Rasool, AH | 1 |
| Quah, BS | 1 |
| Roberton, D | 1 |
| Malin, M | 1 |
| Putto-Laurila, A | 1 |
| Honkanen, V | 1 |
| Zhou, L | 1 |
| Chen, Y | 1 |
| Ye, S | 1 |
| BARTHOLOMEW, LE | 1 |
| Haapasaari, J | 1 |
| Kautiainen, H | 1 |
| Isomäki, H | 2 |
| Hakala, M | 1 |
| Mozziconacci, P | 1 |
| Hayem, F | 1 |
| Guy-Grand, D | 1 |
| Alepa, FP | 1 |
| Baum, J | 2 |
| Sagransky, DM | 1 |
| Greenwald, RA | 1 |
| Gorvoy, JD | 1 |
| Emery, HM | 1 |
| Giannini, EH | 6 |
| Cassidy, JT | 2 |
| Brewer, EJ | 4 |
| Shaikov, A | 1 |
| Maximov, A | 1 |
| Kuzmina, N | 3 |
| Schaller, JG | 1 |
| Muzaffer, MA | 1 |
| Schneider, R | 1 |
| Cameron, BJ | 1 |
| Silverman, ED | 1 |
| Laxer, RM | 1 |
| Savolainen, A | 1 |
| Haagsma, CJ | 1 |
| van Riel, PL | 1 |
| Lomater, G | 1 |
| Gattinara, M | 1 |
| Gerloni, V | 1 |
| Zeni, S | 1 |
| Fantini, F | 1 |
| Moroldo, MB | 1 |
| Singer, NG | 1 |
| McCune, WJ | 1 |
| Barry, PE | 1 |
| Stillman, JS | 2 |
| Chylack, LT | 1 |
| Bienfang, DC | 1 |
| Bellows, AR | 1 |
| Green, WT | 1 |
| Rose, CD | 1 |
| Doughty, RA | 1 |
| Mueller, MN | 1 |
| Høyeraal, HM | 2 |
| van Kerckhove, C | 1 |
| Lovell, DJ | 1 |
| Alekseev, L | 2 |
| Shokh, BP | 1 |
| Dugowson, CE | 1 |
| Gilliland, BC | 1 |
| Tulzer, W | 1 |
| Kvien, TK | 1 |
| Sandstad, B | 1 |
| Henkind, P | 1 |
| Gold, DH | 1 |
| Laaksonen, AL | 3 |
| Koskiahde, V | 2 |
| Juva, K | 3 |
| Sunell, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Anti-TNF Therapy Plus Methotrexate, Combination Therapy of DMARDs, and Methotrexate Alone in Very Early Polyarticular Juvenile Idiopathic Arthritis. A National Randomized Multicenter Clinical Trial.[NCT01015547] | Phase 3 | 60 participants (Actual) | Interventional | 2003-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for hydroxychloroquine and Arthritis, Juvenile
| Article | Year |
|---|---|
COVID-19 and what pediatric rheumatologists should know: a review from a highly affected country.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Beta | 2020 |
Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement.
Topics: Abnormalities, Multiple; Arthritis, Juvenile; Arthroplasty, Replacement, Hip; Arthroplasty, Replacem | 2014 |
The role of synthetic drugs in the biologic era: therapeutic strategies for treating juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Drug Therapy, Combination; Humans; H | 2016 |
Treatment of juvenile rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Erythropoietin; gamma-Globulins | 1993 |
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquin | 1993 |
Combination of second-line antirheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cyclosporine; Drug Therapy, Combinat | 1997 |
Update on immunosuppressive therapy.
Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cycl | 1998 |
Pharmacological management of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, J | 1992 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 1988 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
Rheumatoid arthritis.
Topics: Antigen-Antibody Reactions; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Biopsy; Chloroquine | 1973 |
10 trials available for hydroxychloroquine and Arthritis, Juvenile
| Article | Year |
|---|---|
Health-related quality of life during early aggressive treatment in patients with polyarticular juvenile idiopathic arthritis: results from randomized controlled trial.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Hum | 2019 |
Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE-JIA): a multicentre randomised open-label clinical trial.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Prescho | 2011 |
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquin | 1993 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 1988 |
Characteristics of responders and nonresponders to slow-acting antirheumatic drugs in juvenile rheumatoid arthritis.
Topics: Antibodies, Antinuclear; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Humans; | 1988 |
Poor correlation between the erythrocyte sedimentation rate and clinical activity in juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Blood Sedimentation; Child; Clinical Trials as Topic; Double-Blind | 1987 |
Penicillamine and hydroxychloroquine in the treatment of severe juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind placebo-controlled trial.
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as T | 1986 |
Treatment of children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Clinical Trials as Topic; Humans; Hydroxychloroquine; Penicilla | 1986 |
Slow acting antirheumatic drugs in patients with juvenile rheumatoid arthritis--evaluated in a randomized, parallel 50-week clinical trial.
Topics: Adolescent; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Clinical Trials as To | 1985 |
Dosage of antimalarial drugs for children with juvenile rheumatoid arthritis and systemic lupus erythematosus. A clinical study with determination of serum concentrations of chloroquine and hydroxychloroquine.
Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Chloroquine; Clinical Trials as Top | 1974 |
24 other studies available for hydroxychloroquine and Arthritis, Juvenile
| Article | Year |
|---|---|
Childhood-onset rheumatoid arthritis at a tertiary hospital in Senegal, West Africa.
Topics: Adolescent; Adult; Africa, Western; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Cohort Studie | 2023 |
Susceptibility to COVID-19 in Patients Treated With Antimalarials: A Population-Based Study in Emilia-Romagna, Northern Italy.
Topics: Adult; Aged; Aged, 80 and over; Antimalarials; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, | 2021 |
Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Female; Hemosideros | 2007 |
Still bizarre.
Topics: Abdominal Pain; Adolescent; Arthritis, Juvenile; Bezoars; Drug Therapy, Combination; Humans; Hydroxy | 2012 |
ISOLATION AND CHARACTERIZATION OF MYCOPLASMAS (PPLO) FROM PATIENTS WITH RHEUMATOID ARTHRITIS, SYSTEMIC LUPUS ERYTHEMATOSUS AND REITER'S SYNDROME.
Topics: Adolescent; Arthritis; Arthritis, Juvenile; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Com | 1965 |
Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Child; Female; Humans; Hydroxychloroquine; Male; Methotrexate | 2005 |
[Chronic oligoarthritis in children].
Topics: Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Glucocorticoids; Humans; Hydr | 1967 |
Juvenile rheumatoid arthritis.
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Female; | 1984 |
Pharmacologic treatment of juvenile arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; | 1983 |
Seropositive rheumatoid arthritis in a patient with cystic fibrosis.
Topics: Adolescent; Arthritis, Juvenile; Cystic Fibrosis; Female; Gold Sodium Thiomalate; Humans; Hydroxychl | 1980 |
Treatment of juvenile arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; | 1983 |
Therapy for childhood rheumatic diseases. Have we been doing enough?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Pr | 1993 |
Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Female; Humans; Hydroxychloroquine; Methotrexate; Rheumatoid Factor | 1996 |
[Can indomethacin prolong arthritis?].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Auranofin; Child; Drug Therapy, Combination; Humans; Hydr | 1995 |
Combination therapy of juvenile rheumatoid arthritis with hydroxychloroquine-gold-methotrexate: a pilot study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Hyd | 1994 |
Estimates of the discriminant ability of definitions of improvement for juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Auranofin; Discriminant Analysis; Humans; Hydroxychloroqu | 1998 |
Characteristics of juvenile rheumatoid arthritis: its medical and orthopedic management.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Child; Female; Gold Sodium Thiomala | 1975 |
Ocular manifestations of juvenile rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Arthritis, Juvenile; Atropine; Cataract; Ch | 1975 |
Orthopedic overview of juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Diagnosis, Differential; Female; | 1976 |
Comment on the article by van Kerckhove et al.
Topics: Arthritis, Juvenile; Body Weight; Child; Humans; Hydroxychloroquine; Penicillamine; Time Factors | 1989 |
Temporal patterns of response to D-penicillamine, hydroxychloroquine, and placebo in juvenile rheumatoid arthritis patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Female; Forecasting; Humans; Hy | 1988 |
[Drug therapy of chronic juvenile arthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineop | 1987 |
[Chloroquine and hydroxychloroquine dosage in juvenile rheumatoid arthritis].
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Chloroquine; Corneal | 1974 |
[Treatment of juvenile rheumatoid arthritis with chloroquine phosphate and hydroxychloroquine sulphate. Dosage of syrup and tablets with determinations of serum concentrations].
Topics: Administration, Oral; Arthritis, Juvenile; Child; Child, Preschool; Chloroquine; Female; Humans; Hyd | 1971 |