Page last updated: 2024-10-28

hydroxychloroquine and Alopecia

hydroxychloroquine has been researched along with Alopecia in 40 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Alopecia: Absence of hair from areas where it is normally present.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the relationship between centrifugal lipodystrophy (CLD) and lupus erythematosus panniculitis (LEP), and the efficacy and safety of hydroxychloroquine (HCQ) for treating CLD in children."8.12Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study. ( Gu, Y; Li, Y; Ling, B; Lu, Z; Qiu, Y; Xu, Q; Yao, Z; Yu, H, 2022)
"Recent reports indicate that hydroxychloroquine is a potential new treatment option for alopecia universalis; thus, we aimed to report on the safety and efficacy of hydroxychloroquine in 6 patients with refractory alopecia universalis that were treated with 400 mg/d continuously for ≥6 months."8.02Hydroxychloroquine treatment for Alopecia Universalis: Report of six cases. ( Akdogan, N; Ersoy-Evans, S, 2021)
"Lupus alopecia is usually difficult to treat."5.48Dramatic effect of hydroxychloroquine on lupus alopecia. ( Igari, S; Yamamoto, T, 2018)
"This study aimed to investigate the relationship between centrifugal lipodystrophy (CLD) and lupus erythematosus panniculitis (LEP), and the efficacy and safety of hydroxychloroquine (HCQ) for treating CLD in children."4.12Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study. ( Gu, Y; Li, Y; Ling, B; Lu, Z; Qiu, Y; Xu, Q; Yao, Z; Yu, H, 2022)
"Recent reports indicate that hydroxychloroquine is a potential new treatment option for alopecia universalis; thus, we aimed to report on the safety and efficacy of hydroxychloroquine in 6 patients with refractory alopecia universalis that were treated with 400 mg/d continuously for ≥6 months."4.02Hydroxychloroquine treatment for Alopecia Universalis: Report of six cases. ( Akdogan, N; Ersoy-Evans, S, 2021)
" Following treatment with topical steroids, the skin lesions regressed, but alopecia followed and required hydroxychloroquine."3.80Sub-acute cutaneous lupus erythematosus following nitrofurantoin: causative or coincidental? ( Agarwal, M; Murie, J, 2014)
" We present a unique case of alopecia associated with LET, which was partially responsive to hydroxychloroquine."3.77Lupus erythematosus tumidus with discoid lupus erythematosus-induced alopecia of the scalp. ( Franks, AG; Lehrhoff, S; Patel, R; Sanchez, M; Tzu, J, 2011)
"The following key words, "lupus panniculitis, "lupus erythematosus panniculitis", "lupus profundus", "head", and "scalp", were used."2.61Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature. ( Lueangarun, S; Subpayasarn, U; Tempark, T, 2019)
"Treatment with hydroxychloroquine and local steroid injection resulted in complete hair regrowth but recurrence was noted."2.48Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a distinct variant of lupus panniculitis in East Asians? ( Chen, YA; Hsu, CK; Lee, JY; Yang, CC, 2012)
"A 34-year-old woman presented with hair loss to the parietal region."1.56Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction. ( Kambe, N; Okamoto, H; Son, Y; Takezawa, K; Ueda-Hayakawa, I; Yamazaki, F, 2020)
"Lupus alopecia is usually difficult to treat."1.48Dramatic effect of hydroxychloroquine on lupus alopecia. ( Igari, S; Yamamoto, T, 2018)
"One patient had hair loss of the upper cutaneous lip."1.46Frontal fibrosing alopecia among men: A clinicopathologic study of 7 cases. ( Camilleri, MJ; Chaudhry, HM; Tolkachjov, SN; Torgerson, RR, 2017)
"FFA is an increasingly common form of scarring hair loss, but the origin remains unknown."1.39Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University. ( Bazakas, A; Ladizinski, B; Olsen, EA; Selim, MA, 2013)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.50)18.7374
1990's2 (5.00)18.2507
2000's0 (0.00)29.6817
2010's23 (57.50)24.3611
2020's14 (35.00)2.80

Authors

AuthorsStudies
Paudel, V1
Chudal, D1
Pradhan, MB1
Thakur, R1
Pandey, BR1
Collins, M1
Ali, S1
Wiss, IP1
Senna, MM4
Kępińska, K1
Jałowska, M1
Bowszyc-Dmochowska, M1
Collins, MS1
Ezemma, O3
Devjani, S3
Klein, EJ1
Karim, M1
Lo Sicco, K1
Shapiro, J2
Xu, Q1
Qiu, Y1
Lu, Z1
Yu, H1
Ling, B1
Li, Y1
Gu, Y1
Yao, Z1
Jothishankar, BA1
Kelley, KJ2
Senna, M1
Jothishankar, B1
Orlando, G1
Salmaso, R1
Piaserico, S1
Suchonwanit, P1
Pakornphadungsit, K1
Leerunyakul, K1
Khunkhet, S1
Sriphojanart, T1
Rojhirunsakool, S1
Takezawa, K1
Ueda-Hayakawa, I1
Yamazaki, F1
Kambe, N1
Son, Y1
Okamoto, H1
Akdogan, N1
Ersoy-Evans, S1
Kłosowicz, A1
Pastuszczak, M1
Dyduch, G1
Englert, K1
Łukasik, A1
Wojas-Pelc, A1
Pathoulas, JT1
Flanagan, KE1
Walker, CJ1
Pupo Wiss, IM1
Hagigeorges, D1
Shaw, KS1
Yin, L1
Shah, JK1
Sally, RA1
Svigos, KS1
Adotama, PU1
Tuan, HH1
Betensky, RA1
Lo Siccoa, KI1
Tolkachjov, SN1
Chaudhry, HM1
Camilleri, MJ1
Torgerson, RR1
Darjani, A1
Rafiei, R1
Mesbah, A1
Golmohammadi, R1
Rafiee, B1
Movaseghi, M1
Igari, S1
Yamamoto, T1
Lueangarun, S1
Subpayasarn, U1
Tempark, T1
Olsavszky, V1
Géraud, C1
Felcht, M1
Zhou, MY1
Tan, C1
Stephan, F1
Habre, M1
Tomb, R1
Khayat, R1
Dupuy, A1
Pansé, I1
Bagot, M1
Cordoliani, F1
Gupta, R1
High, WA1
Butler, D1
Murase, JE1
Murie, J1
Agarwal, M1
Gameza, VA1
Deleuran, M1
Park, SK1
Kwak, HB1
Yun, SK1
Kim, HU1
Park, J1
Chiang, C1
Sah, D1
Cho, BK1
Ochoa, BE1
Price, VH1
Sperling, LC1
Nguyen, JV1
Ahiarah, A1
Sauret, J1
Samrao, A1
Chew, AL1
Price, V1
Donati, A1
Assouly, P1
Matard, B1
Jouanique, C1
Reygagne, P1
Agozzino, M1
Tosti, A1
Barbieri, L1
Moscarella, E1
Cota, C1
Berardesca, E1
Ardigò, M1
Lehrhoff, S1
Tzu, J1
Patel, R2
Sanchez, M1
Franks, AG1
Vashi, N1
Newlove, T1
Chu, J1
Stein, J1
Chen, YA1
Hsu, CK1
Lee, JY1
Yang, CC1
Ladizinski, B1
Bazakas, A1
Selim, MA1
Olsen, EA1
Nashel, DJ1
Ulmer, CC1
Bergner, T1
Braun-Falco, O1
Bulengo-Ransby, SM1
Headington, JT1

Reviews

4 reviews available for hydroxychloroquine and Alopecia

ArticleYear
Frontal Fibrosing Alopecia - a review and a practical guide for clinicians.
    Annals of agricultural and environmental medicine : AAEM, 2022, Jun-24, Volume: 29, Issue:2

    Topics: Alopecia; Child, Preschool; Female; Forehead; Humans; Hydroxychloroquine; Lichen Planus; Scalp

2022
Adverse effects of hydroxychloroquine use in patients with cicatricial alopecia: A systematic review.
    International journal of dermatology, 2023, Volume: 62, Issue:9

    Topics: Alopecia; Cicatrix; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxychloroquine; Iat

2023
Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature.
    International journal of dermatology, 2019, Volume: 58, Issue:2

    Topics: Administration, Oral; Adrenal Cortex Hormones; Alopecia; Humans; Hydroxychloroquine; Immunosuppressi

2019
Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a distinct variant of lupus panniculitis in East Asians?
    The Journal of dermatology, 2012, Volume: 39, Issue:4

    Topics: Adult; Alopecia; Asian People; Humans; Hydroxychloroquine; Male; Panniculitis, Lupus Erythematosus;

2012

Other Studies

36 other studies available for hydroxychloroquine and Alopecia

ArticleYear
Alopecia Universalis Associated with Hyperthyroidism Treated with Azathioprine and Hydroxychloroquine: A Case Report.
    JNMA; journal of the Nepal Medical Association, 2021, Sep-11, Volume: 59, Issue:241

    Topics: Alopecia; Alopecia Areata; Azathioprine; Female; Humans; Hydroxychloroquine; Hyperthyroidism

2021
Retrospective review of adverse events associated with oral hydroxychloroquine use in patients with cicatricial alopecia.
    Journal of the American Academy of Dermatology, 2023, Volume: 88, Issue:2

    Topics: Alopecia; Cicatrix; Hair; Humans; Hydroxychloroquine; Retrospective Studies

2023
Reply to "Response to Collins et al.'s 'Retrospective review of adverse events associated with oral hydroxychloroquine use in patients with cicatricial alopecia'".
    Journal of the American Academy of Dermatology, 2022, Volume: 87, Issue:6

    Topics: Alopecia; Cicatrix; Humans; Hydroxychloroquine; Retrospective Studies

2022
Response to the study by Collins et al "Retrospective review of adverse events associated with oral hydroxychloroquine use in patients with cicatricial alopecia."
    Journal of the American Academy of Dermatology, 2022, Volume: 87, Issue:6

    Topics: Alopecia; Cicatrix; Humans; Hydroxychloroquine; Lichen Planus; Retrospective Studies

2022
Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study.
    Dermatologic therapy, 2022, Volume: 35, Issue:11

    Topics: Alopecia; Child; Female; Humans; Hydroxychloroquine; Infant; Lipodystrophy; Male; Panniculitis; Pann

2022
Assessment of hydroxychloroquine use and QT interval duration in female patients with frontal fibrosing alopecia.
    International journal of dermatology, 2023, Volume: 62, Issue:9

    Topics: Alopecia; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus

2023
A Case of Secondary Osteoma Cutis Associated with Lichen Planopilaris.
    Acta dermato-venereologica, 2019, Nov-01, Volume: 99, Issue:12

    Topics: Alopecia; Bone Diseases, Metabolic; Clobetasol; Female; Glucocorticoids; Humans; Hydroxychloroquine;

2019
Frontal fibrosing alopecia in Asians: a retrospective clinical study.
    International journal of dermatology, 2020, Volume: 59, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Alopecia; Asi

2020
Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction.
    Lupus, 2020, Volume: 29, Issue:1

    Topics: Adult; Alopecia; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antirheumatic Agents; Fema

2020
Hydroxychloroquine treatment for Alopecia Universalis: Report of six cases.
    The Australasian journal of dermatology, 2021, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Alopecia; Child; Female; Humans; Hydroxychloroquine; Immunologic Factors; Male; S

2021
Dendritic cells as predictive markers of responsiveness to hydroxychloroquine treatment in primary cicatricial alopecia patients.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Alopecia; Biomarkers; Dendritic Cells; Humans; Hydroxychloroquine; Retrospective Studies

2020
Hydroxychloroquine use and COVID-19 concerns among alopecia patients: A cross-sectional survey study.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Aged; Alopecia; COVID-19 Drug Treatment; Cross-Sectional Studies; Female; Humans; Hydroxychloroquine

2020
COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched Analysis of Cicatricial Alopecia Patients.
    Journal of drugs in dermatology : JDD, 2021, Aug-01, Volume: 20, Issue:8

    Topics: Alopecia; Antiviral Agents; Cicatrix; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics

2021
Frontal fibrosing alopecia among men: A clinicopathologic study of 7 cases.
    Journal of the American Academy of Dermatology, 2017, Volume: 77, Issue:4

    Topics: Adult; Aged; Alopecia; Anti-Inflammatory Agents; Cheek; Cicatrix; Clobetasol; Dermatologic Agents; E

2017
Discoid Lupus Erythematosus Presenting as Upper Eyelid Edema and Erythema.
    Acta medica Iranica, 2017, Volume: 55, Issue:7

    Topics: Adult; Alopecia; Edema; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid;

2017
Dramatic effect of hydroxychloroquine on lupus alopecia.
    The Journal of dermatology, 2018, Volume: 45, Issue:2

    Topics: Administration, Oral; Adult; Alopecia; Antirheumatic Agents; Biopsy; Dermatitis, Atopic; Female; Hum

2018
Disseminated Small Papules on the Face: A Quiz.
    Acta dermato-venereologica, 2019, May-01, Volume: 99, Issue:6

    Topics: Alopecia; Clobetasol; Eyebrows; Facial Dermatoses; Female; Glucocorticoids; Hair Follicle; Humans; H

2019
Comedonic discoid lupus erythematous.
    Scandinavian journal of rheumatology, 2019, Volume: 48, Issue:4

    Topics: Alopecia; Antirheumatic Agents; Biopsy; Diagnosis, Differential; Drug Administration Routes; Humans;

2019
Successful treatment of alopecia totalis with hydroxychloroquine: report of 2 cases.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:6

    Topics: Adult; Alopecia; Antimalarials; Female; Humans; Hydroxychloroquine; Young Adult

2013
[Sclerodermatous changes in porphyria cutanea tarda: six cases].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Alcoholism; Alopecia; Diagnosis, Differential; Female; Humans; Hydrox

2013
Medicolegal aspects of prescribing dermatological medications in pregnancy.
    Seminars in cutaneous medicine and surgery, 2013, Volume: 32, Issue:4

    Topics: Acne Vulgaris; Alopecia; Dermatitis, Atopic; Dermatologic Agents; Dermatology; Female; Fetal Disease

2013
Sub-acute cutaneous lupus erythematosus following nitrofurantoin: causative or coincidental?
    Scottish medical journal, 2014, Volume: 59, Issue:4

    Topics: Aged; Alopecia; Anti-Infective Agents, Urinary; Enzyme Inhibitors; Female; Humans; Hydroxychloroquin

2014
[Frontal fibrosing alopecia is a variant of lichen planopilaris].
    Ugeskrift for laeger, 2015, Jan-26, Volume: 177, Issue:2A

    Topics: Aged; Alopecia; Enzyme Inhibitors; Female; Humans; Hydroxychloroquine; Lichen Planus

2015
Two Annular Alopecic Lesions on the Scalp in a Young Asian Man: A Quiz.
    Acta dermato-venereologica, 2017, 03-10, Volume: 97, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Alopecia; Biop

2017
Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:3

    Topics: Adult; Alopecia; Cicatrix; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus; Male; Middle

2010
Commentary: treatment of lichen planopilaris: some progress, but a long way to go.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:3

    Topics: Adrenal Cortex Hormones; Alopecia; Clinical Trials as Topic; Cyclosporine; Female; Humans; Hydroxych

2010
A progressive scalp lesion.
    The Journal of family practice, 2010, Volume: 59, Issue:4

    Topics: Alopecia; Antimalarials; Female; Humans; Hydroxychloroquine; Hyperpigmentation; Hypopigmentation; Lu

2010
Frontal fibrosing alopecia: a clinical review of 36 patients.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Anti-Bacterial Agents; Cohort Studies; Dermatologic Agents

2010
Clinical and photographic assessment of lichen planopilaris treatment efficacy.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:3

    Topics: Alopecia; Humans; Hydroxychloroquine; Lichen Planus; Scalp Dermatoses; Treatment Outcome

2011
Confocal microscopic features of scarring alopecia: preliminary report.
    The British journal of dermatology, 2011, Volume: 165, Issue:3

    Topics: Aged; Alopecia; Anti-Inflammatory Agents; Clobetasol; Dermatologic Agents; Female; Humans; Hydroxych

2011
Lupus erythematosus tumidus with discoid lupus erythematosus-induced alopecia of the scalp.
    Dermatology online journal, 2011, Oct-15, Volume: 17, Issue:10

    Topics: Adult; Alopecia; Antibodies, Antinuclear; Black or African American; Dermis; Humans; Hydroxychloroqu

2011
Graham-Little-Piccardi-Lassueur syndrome.
    Dermatology online journal, 2011, Oct-15, Volume: 17, Issue:10

    Topics: Adult; Alopecia; Axilla; Doxycycline; Female; Groin; Humans; Hydroxychloroquine; Hyperpigmentation;

2011
Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Alopecia; Anti-Bacterial Agents; Azasteroids; Cicatrix; D

2013
Systemic lupus erythematosus: important considerations in the adolescent.
    Journal of adolescent health care : official publication of the Society for Adolescent Medicine, 1982, Volume: 2, Issue:4

    Topics: Adolescent; Alopecia; Anxiety; Chronic Disease; Depression; Female; Humans; Hydroxychloroquine; Lupu

1982
Pseudopelade of Brocq.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 1

    Topics: Adolescent; Adult; Alopecia; Child; Cicatrix; Female; Humans; Hydroxychloroquine; Male

1991
Pseudopelade of Brocq in a child.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:5 Pt 1

    Topics: Alopecia; Child, Preschool; Female; Humans; Hydroxychloroquine; Scalp

1990