hydroxychloroquine has been researched along with Allergic Encephalomyelitis in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) is an antimalarial drug with immunomodulatory properties that is widely used in the treatment of rheumatological diseases." | 1.42 | Hydroxychloroquine reduces microglial activity and attenuates experimental autoimmune encephalomyelitis. ( Giuliani, F; Hader, W; Koch, MW; Lewkonia, R; Metz, L; Wee Yong, V; Zabad, R, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faissner, S | 1 |
| Mahjoub, Y | 1 |
| Mishra, M | 1 |
| Haupeltshofer, S | 1 |
| Hahn, JN | 1 |
| Gold, R | 1 |
| Koch, M | 1 |
| Metz, LM | 1 |
| Ben-Hur, T | 1 |
| Yong, VW | 1 |
| Koch, MW | 1 |
| Zabad, R | 1 |
| Giuliani, F | 1 |
| Hader, W | 1 |
| Lewkonia, R | 1 |
| Metz, L | 1 |
| Wee Yong, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydroxychloroquine Assessment of Management Study in Coronary Artery Disease After Angiography.[NCT02874287] | Phase 4 | 35 participants (Actual) | Interventional | 2017-10-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for hydroxychloroquine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?
Topics: Animals; B-Lymphocytes; Cell Proliferation; Disease Models, Animal; Encephalomyelitis, Autoimmune, E | 2018 |
Hydroxychloroquine reduces microglial activity and attenuates experimental autoimmune encephalomyelitis.
Topics: Animals; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Humans; Hydroxychloroquine; Macroph | 2015 |