hydroxychloroquine has been researched along with Adjuvant Arthritis in 6 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) is one of the most commonly prescribed immune-suppressants in treating rheumatoid arthritis (RA)." | 7.96 | The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling. ( Han, J; Han, Y; He, J; He, Y; Huang, X; Jie, H; Li, X; Li, Y; Luo, X; Sun, E; Wu, S; Yang, B; Yang, F; Zhai, Z; Zhou, Q; Zhuang, J, 2020) |
| "Hydroxychloroquine (HCQ) is one of the most commonly prescribed immune-suppressants in treating rheumatoid arthritis (RA)." | 3.96 | The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling. ( Han, J; Han, Y; He, J; He, Y; Huang, X; Jie, H; Li, X; Li, Y; Luo, X; Sun, E; Wu, S; Yang, B; Yang, F; Zhai, Z; Zhou, Q; Zhuang, J, 2020) |
| "Hydroxychloroquine (HCQ) is an immunosuppressive agent widely used in rheumatoid arthritis (RA)." | 3.88 | Novel function of hydroxychloroquine: Down regulation of T follicular helper cells in collagen-induced arthritis. ( Han, J; Han, Y; He, J; He, Y; Jie, H; Li, X; Sun, E; Zhou, Q, 2018) |
| "The pharmacokinetic studies were carried out following administration of 40 mg/kg of racemic HCQ to diabetic, insulin-treated diabetic, adjuvant arthritic and control rats." | 1.30 | Effect of experimental diabetes mellitus and arthritis on the pharmacokinetics of hydroxychloroquine enantiomers in rats. ( Emami, J; Jamali, F; Pasutto, FM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Akhtar, MF | 1 |
| Zubair, S | 1 |
| Saleem, A | 1 |
| Alsharif, KF | 1 |
| Abdel-Daim, MM | 1 |
| Han, J | 2 |
| Li, X | 2 |
| Luo, X | 1 |
| He, J | 2 |
| Huang, X | 1 |
| Zhou, Q | 2 |
| Han, Y | 2 |
| Jie, H | 2 |
| Zhuang, J | 1 |
| Li, Y | 1 |
| Yang, F | 1 |
| Zhai, Z | 1 |
| Wu, S | 1 |
| He, Y | 2 |
| Yang, B | 1 |
| Sun, E | 2 |
| Poorvashree, J | 1 |
| Suneela, D | 1 |
| Jančinová, V | 1 |
| Pažoureková, S | 1 |
| Lucová, M | 1 |
| Perečko, T | 1 |
| Mihalová, D | 1 |
| Bauerová, K | 1 |
| Nosáľ, R | 1 |
| Drábiková, K | 1 |
| Emami, J | 1 |
| Pasutto, FM | 1 |
| Jamali, F | 1 |
6 other studies available for hydroxychloroquine and Adjuvant Arthritis
| Article | Year |
|---|---|
Comparison of individual and combination treatments with naproxen, prednisolone and hydroxychloroquine to treat Complete Freund's Adjuvant induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Erythrocytes; Fema | 2021 |
The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling.
Topics: Adult; Aged; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Case-Con | 2020 |
Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, R | 2017 |
Novel function of hydroxychloroquine: Down regulation of T follicular helper cells in collagen-induced arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; Cytokines; | 2018 |
Selective inhibition of extracellular oxidants liberated from human neutrophils--A new mechanism potentially involved in the anti-inflammatory activity of hydroxychloroquine.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Experimental; Calc | 2015 |
Effect of experimental diabetes mellitus and arthritis on the pharmacokinetics of hydroxychloroquine enantiomers in rats.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Diabetes Mellitus, Experimental; Hydroxychlo | 1998 |