hydroxychloroquine has been researched along with Acute Kidney Failure in 27 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions." | 8.12 | Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis. ( An, N; Chen, RH; Guo, Y; Huang, TS; Huang, XJ; Li, ZH; Liu, HF; Pan, QJ; Wu, HL; Wu, ZH; Xue, J; Yang, C, 2022) |
| "Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions." | 4.12 | Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis. ( An, N; Chen, RH; Guo, Y; Huang, TS; Huang, XJ; Li, ZH; Liu, HF; Pan, QJ; Wu, HL; Wu, ZH; Xue, J; Yang, C, 2022) |
| "Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period." | 1.62 | A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report. ( Afrooz, N; Aminimoghaddam, S; Mahmoudzadeh, F; Motaghi Nejad, O; Nasiri, S, 2021) |
| "The novel coronavirus disease 2019 (COVID-19) is a respiratory infection that has received much attention due to its rapid expansion." | 1.62 | COVID-19 progression in kidney transplant recipients: a single-center case series. ( Keykhaei, M; Mansouri, ES; Rahimzadeh, H; Razeghi, E; Zivari, E, 2021) |
| "The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy." | 1.56 | Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020) |
| "Methemoglobinemia is a rare disorder of the blood in which there is an increase in methemoglobin, which occurs when hemoglobin is present in the oxidized form." | 1.56 | Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report. ( Bloom, A; Faisal, H; Gaber, AO, 2020) |
| "Hydroxychloroquine-treated lupus patients showed a lower incidence of thromboembolic disease." | 1.40 | Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus. ( Algieri, F; Duarte, J; Gálvez, J; Gómez-Guzmán, M; Gómez-Morales, M; Jiménez, R; López-Farré, AJ; O'Valle, F; Pérez-Vizcaino, F; Romero, M; Sabio, JM; Sánchez, M; Zarzuelo, MJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 23 (85.19) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, JX | 1 |
| Williamson, KA | 1 |
| Duarte-García, A | 1 |
| An, N | 1 |
| Yang, C | 1 |
| Wu, HL | 1 |
| Guo, Y | 1 |
| Huang, XJ | 1 |
| Huang, TS | 1 |
| Wu, ZH | 1 |
| Xue, J | 1 |
| Chen, RH | 1 |
| Li, ZH | 1 |
| Pan, QJ | 1 |
| Liu, HF | 1 |
| Kajani, R | 1 |
| Apramian, A | 1 |
| Vega, A | 1 |
| Ubhayakar, N | 1 |
| Xu, P | 1 |
| Liu, A | 1 |
| Edelstein, CL | 1 |
| Venkatachalam, MA | 1 |
| Dong, Z | 1 |
| Mella, A | 1 |
| Mingozzi, S | 1 |
| Gallo, E | 1 |
| Lavacca, A | 1 |
| Rossetti, M | 1 |
| Clari, R | 1 |
| Randone, O | 1 |
| Maffei, S | 1 |
| Salomone, M | 1 |
| Imperiale, D | 1 |
| Biancone, L | 1 |
| Painvin, B | 1 |
| Guillot, P | 1 |
| Verdier, MC | 1 |
| Gacouin, A | 1 |
| Maamar, A | 1 |
| Breslin, N | 1 |
| Baptiste, C | 1 |
| Miller, R | 1 |
| Fuchs, K | 1 |
| Goffman, D | 1 |
| Gyamfi-Bannerman, C | 1 |
| D'Alton, M | 1 |
| Chen, TY | 1 |
| Farghaly, S | 1 |
| Cham, S | 1 |
| Tatem, LL | 1 |
| Sin, JH | 1 |
| Rauda, R | 1 |
| Ribisi, M | 1 |
| Sumrani, N | 1 |
| Maritati, F | 1 |
| Cerutti, E | 1 |
| Zuccatosta, L | 1 |
| Fiorentini, A | 1 |
| Finale, C | 1 |
| Ficosecco, M | 1 |
| Cristiano, F | 1 |
| Capestro, A | 1 |
| Balestra, E | 1 |
| Taruscia, D | 1 |
| Vivarelli, M | 1 |
| Donati, A | 1 |
| Perna, GP | 1 |
| Giacometti, A | 1 |
| Tavio, M | 1 |
| Onesta, M | 1 |
| Di Sante, L | 1 |
| Ranghino, A | 1 |
| Mehta, SA | 1 |
| Leonard, J | 1 |
| Labella, P | 1 |
| Cartiera, K | 1 |
| Soomro, I | 1 |
| Neumann, H | 1 |
| Montgomery, RA | 1 |
| Ali, NM | 1 |
| Dajti, E | 1 |
| Cristini, F | 1 |
| Tamanini, G | 1 |
| Cescon, M | 1 |
| Bazzoli, F | 1 |
| Tamè, M | 1 |
| Faisal, H | 1 |
| Bloom, A | 1 |
| Gaber, AO | 1 |
| Sosa-García, JO | 1 |
| Gutiérrez-Villaseñor, AO | 1 |
| García-Briones, A | 1 |
| Romero-González, JP | 1 |
| Juárez-Hernández, E | 1 |
| González-Chon, O | 1 |
| Trujillo, H | 1 |
| Fernández-Ruiz, M | 1 |
| Gutiérrez, E | 1 |
| Sevillano, Á | 1 |
| Caravaca-Fontán, F | 1 |
| Morales, E | 1 |
| López-Medrano, F | 1 |
| Aguado, JM | 1 |
| Praga, M | 1 |
| Andrés, A | 1 |
| Obeidat, M | 1 |
| Isaacson, AL | 1 |
| Chen, SJ | 1 |
| Ivanovic, M | 1 |
| Holanda, D | 1 |
| Gomes, CP | 1 |
| Fernandes, DE | 1 |
| Casimiro, F | 1 |
| da Mata, GF | 1 |
| Passos, MT | 1 |
| Varela, P | 1 |
| Mastroianni-Kirsztajn, G | 1 |
| Pesquero, JB | 1 |
| Mungmunpuntipantip, R | 1 |
| Wiwanitkit, V | 1 |
| Aminimoghaddam, S | 1 |
| Afrooz, N | 1 |
| Nasiri, S | 1 |
| Motaghi Nejad, O | 1 |
| Mahmoudzadeh, F | 1 |
| Rahimzadeh, H | 1 |
| Keykhaei, M | 1 |
| Razeghi, E | 1 |
| Zivari, E | 1 |
| Mansouri, ES | 1 |
| Alser, O | 1 |
| Mokhtari, A | 1 |
| Naar, L | 1 |
| Langeveld, K | 1 |
| Breen, KA | 1 |
| El Moheb, M | 1 |
| Kapoen, C | 1 |
| Gaitanidis, A | 1 |
| Christensen, MA | 1 |
| Maurer, LR | 1 |
| Mashbari, H | 1 |
| Bankhead-Kendall, B | 1 |
| Parks, J | 1 |
| Fawley, J | 1 |
| Saillant, N | 1 |
| Mendoza, A | 1 |
| Paranjape, C | 1 |
| Fagenholz, P | 1 |
| King, D | 1 |
| Lee, J | 1 |
| Farhat, MR | 1 |
| Velmahos, GC | 1 |
| Kaafarani, HMA | 1 |
| Schneider, J | 1 |
| Jaenigen, B | 1 |
| Wagner, D | 1 |
| Rieg, S | 1 |
| Hornuss, D | 1 |
| Biever, PM | 1 |
| Kern, WV | 1 |
| Walz, G | 1 |
| de Almeida, DC | 1 |
| Franco, MDCP | 1 |
| Dos Santos, DRP | 1 |
| Santos, MC | 1 |
| Maltoni, IS | 1 |
| Mascotte, F | 1 |
| de Souza, AA | 1 |
| Pietrobom, PM | 1 |
| Medeiros, EA | 1 |
| Ferreira, PRA | 1 |
| Machado, FR | 1 |
| Goes, MA | 1 |
| Yilmaz, G | 1 |
| Ebru, O | 1 |
| Ibrahim, B | 1 |
| Ulkem, C | 1 |
| Tang, TT | 1 |
| Lv, LL | 1 |
| Pan, MM | 1 |
| Wen, Y | 1 |
| Wang, B | 1 |
| Li, ZL | 1 |
| Wu, M | 1 |
| Wang, FM | 1 |
| Crowley, SD | 1 |
| Liu, BC | 1 |
| Gómez-Guzmán, M | 1 |
| Jiménez, R | 1 |
| Romero, M | 1 |
| Sánchez, M | 1 |
| Zarzuelo, MJ | 1 |
| Gómez-Morales, M | 1 |
| O'Valle, F | 1 |
| López-Farré, AJ | 1 |
| Algieri, F | 1 |
| Gálvez, J | 1 |
| Pérez-Vizcaino, F | 1 |
| Sabio, JM | 1 |
| Duarte, J | 1 |
| Awdishu, L | 1 |
| Joy, MS | 1 |
| Samson, M | 1 |
| Audia, S | 1 |
| Leguy, V | 1 |
| Berthier, S | 1 |
| Janikashvili, N | 1 |
| Martin, L | 1 |
| Bonnotte, B | 1 |
| Lorcerie, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-ventilated Prone Positioning in the COVID-19 Population[NCT05957588] | 216 participants (Actual) | Interventional | 2021-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydroxychloroquine and Acute Kidney Failure
| Article | Year |
|---|---|
Invasive pulmonary aspergillosis associated with COVID-19 in a kidney transplant recipient.
Topics: Acute Kidney Injury; Administration, Inhalation; Amphotericin B; Anti-Bacterial Agents; Antibodies, | 2021 |
Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics.
Topics: Acute Kidney Injury; Amantadine; Angiotensin-Converting Enzyme 2; Cathepsin L; Chloroquine; COVID-19 | 2020 |
Role of Pharmacogenomics in Kidney Disease and Injury.
Topics: Acute Kidney Injury; Azathioprine; Calcineurin Inhibitors; Cisplatin; Cyclophosphamide; Cytochrome P | 2016 |
24 other studies available for hydroxychloroquine and Acute Kidney Failure
| Article | Year |
|---|---|
75-Year-Old Man With Fever and Malaise.
Topics: Acute Kidney Injury; Aged; Antirheumatic Agents; Diagnosis, Differential; Humans; Hydroxychloroquine | 2021 |
Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis.
Topics: Acute Kidney Injury; Animals; Female; Hydroxychloroquine; Kidney; Lupus Nephritis; Mice; Mice, Inbre | 2022 |
Neuroleptic malignant syndrome in a COVID-19 patient.
Topics: Acute Kidney Injury; Antipsychotic Agents; Betacoronavirus; Bromocriptine; C-Reactive Protein; Coron | 2020 |
Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19.
Topics: Acute Kidney Injury; Autophagy; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Crit | 2020 |
Case series of six kidney transplanted patients with COVID-19 pneumonia treated with tocilizumab.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antivira | 2020 |
Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study.
Topics: Acute Kidney Injury; Aged; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatmen | 2020 |
Coronavirus disease 2019 in pregnancy: early lessons.
Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi | 2020 |
COVID-19 pneumonia in kidney transplant recipients: Focus on immunosuppression management.
Topics: Acute Kidney Injury; Adult; Aged; Azithromycin; Calcineurin Inhibitors; COVID-19; COVID-19 Nucleic A | 2020 |
SARS-CoV-2 infection in kidney transplant recipients: Experience of the italian marche region.
Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Antiviral Agents; COVID-19; Drug Thera | 2020 |
Outpatient management of kidney transplant recipients with suspected COVID-19-Single-center experience during the New York City surge.
Topics: Acute Kidney Injury; Ambulatory Care; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Azit | 2020 |
COVID-19 in a young liver transplant recipient: caution for drug-drug interactions.
Topics: Acute Kidney Injury; Adult; Antiviral Agents; Betacoronavirus; Clinical Laboratory Techniques; Coron | 2020 |
Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report.
Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Antioxidants; Ascorbic Acid; Betacoron | 2020 |
Experience in the management of severe COVID-19 patients in an intensive care unit.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Aged; Antibodies, Monoclonal, Humanized; Antiviral Age | 2020 |
Zebra-like bodies in COVID-19: is phospholipidosis evidence of hydroxychloroquine induced acute kidney injury?
Topics: Acute Kidney Injury; Aged; Antiviral Agents; Autopsy; COVID-19 Drug Treatment; Fatal Outcome; Humans | 2020 |
Zebra-like bodies in COVID-19, hydroxychloroquine, and acute renal injury.
Topics: Acute Kidney Injury; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; SARS-CoV-2 | 2021 |
A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report.
Topics: Acute Kidney Injury; Amphetamine-Related Disorders; Antiviral Agents; COVID-19; Drug Combinations; E | 2021 |
COVID-19 progression in kidney transplant recipients: a single-center case series.
Topics: Acute Kidney Injury; Adult; Antimalarials; Antiviral Agents; COVID-19; Disease Progression; Female; | 2021 |
Multisystem outcomes and predictors of mortality in critically ill patients with COVID-19: Demographics and disease acuity matter more than comorbidities or treatment modalities.
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Aged, 80 and over; Antimalarials; Boston; Comorbidity | 2021 |
Therapy with lopinavir/ritonavir and hydroxychloroquine is associated with acute kidney injury in COVID-19 patients.
Topics: Acute Kidney Injury; Aged; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Creatinine; Drug The | 2021 |
Acute kidney injury: Incidence, risk factors, and outcomes in severe COVID-19 patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Azithromycin; Brazil; | 2021 |
Assessment of clinical outcomes in renal transplant recipients with COVID-19.
Topics: Acute Kidney Injury; Adult; Aged; Comorbidity; COVID-19; Female; Humans; Hydroxychloroquine; Immunoc | 2021 |
Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cathepsin B; Cathepsin L; Cell Line; Cell Su | 2018 |
Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme | 2014 |
Haemolytic-uraemic syndrome during severe lupus nephritis: efficacy of plasma exchange.
Topics: Acute Kidney Injury; Adult; Biopsy; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combi | 2012 |