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hydroxychloroquine and Acute Generalised Exanthematous Pustulosis

hydroxychloroquine has been researched along with Acute Generalised Exanthematous Pustulosis in 30 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"severe distinctive cutaneous drug reaction, generalized pustular figurate erythema, closely linked with hydroxychloroquine (HCQ), has been documented."9.22Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review. ( Al Muqarrab, F; Almohssen, AA; Schwartz, RA, 2022)
"Hydroxychloroquine (HCQ)-induced acute generalized exanthematous pustulosis (AGEP) is poorly described in the literature."9.12Hydroxychloroquine-induced acute generalized exanthematous pustulosis: a series of seven patients and review of the literature. ( Amouri, M; Atheymen, R; Bahloul, E; Boudaya, S; Bougacha, N; Chaabouni, R; Charfi, S; Ennouri, M; Marrakchi, S; Sellami, K; Turki, H, 2021)
"A 28-year-old woman with rheumatoid arthritis, treated with leflunomide therapy without marked relief of joint pain, developed multiple rashes with pruritis covering the body 5 days after switching to hydroxychloroquine treatment."8.31Acute generalized exanthematous pustulosis caused by hydroxychloroquine in a patient with rheumatoid arthritis and CARD14 mutation: Case report. ( Chen, CM; Luo, F; Ma, WK; Xiong, H; Yao, XM; Yuan, XM, 2023)
" Four weeks prior, she had been initiated on hydroxychloroquine for a presumed diagnosis of cutaneous sarcoidosis."7.96Acute generalized exanthematous pustulosis and Stevens-Johnson syndrome overlap due to hydroxychloroquine: a case report. ( Ackerman, L; Brahmbhatt, S; Coleman, I; Ruiz, G, 2020)
" HCQ is generally safe and may be prescribed to pregnant women."5.91Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Kaneko, K; Murashima, A; Sago, H; Tanaka, R; Tsurane, K; Yoshida, K, 2023)
"severe distinctive cutaneous drug reaction, generalized pustular figurate erythema, closely linked with hydroxychloroquine (HCQ), has been documented."5.22Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review. ( Al Muqarrab, F; Almohssen, AA; Schwartz, RA, 2022)
"Hydroxychloroquine (HCQ)-induced acute generalized exanthematous pustulosis (AGEP) is poorly described in the literature."5.12Hydroxychloroquine-induced acute generalized exanthematous pustulosis: a series of seven patients and review of the literature. ( Amouri, M; Atheymen, R; Bahloul, E; Boudaya, S; Bougacha, N; Chaabouni, R; Charfi, S; Ennouri, M; Marrakchi, S; Sellami, K; Turki, H, 2021)
"A 28-year-old woman with rheumatoid arthritis, treated with leflunomide therapy without marked relief of joint pain, developed multiple rashes with pruritis covering the body 5 days after switching to hydroxychloroquine treatment."4.31Acute generalized exanthematous pustulosis caused by hydroxychloroquine in a patient with rheumatoid arthritis and CARD14 mutation: Case report. ( Chen, CM; Luo, F; Ma, WK; Xiong, H; Yao, XM; Yuan, XM, 2023)
" Four weeks prior, she had been initiated on hydroxychloroquine for a presumed diagnosis of cutaneous sarcoidosis."3.96Acute generalized exanthematous pustulosis and Stevens-Johnson syndrome overlap due to hydroxychloroquine: a case report. ( Ackerman, L; Brahmbhatt, S; Coleman, I; Ruiz, G, 2020)
"Herein, acute generalized exanthematous pustulosis incited by hydroxychloroquine is briefly reviewed: a prolonged latency and recalcitrance to corticosteroids are noteworthy."2.58Cyclosporine for corticosteroid-refractory acute generalized exanthematous pustulosis due to hydroxychloroquine. ( Castner, NB; Harris, JC; Motaparthi, K, 2018)
" HCQ is generally safe and may be prescribed to pregnant women."1.91Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus. ( Kaneko, K; Murashima, A; Sago, H; Tanaka, R; Tsurane, K; Yoshida, K, 2023)
"Hydroxychloroquine is a medication that is used for the treatment of rheumatic and dermatologic conditions."1.62The necessity of patch testing in determining the causative drug of AGEP. ( Ghobadi Aski, S; Mofarrah, R; Nazemi, N; Nooshiravanpoor, P; Oshriehye, M, 2021)
"BACKGROUND Acute generalized exanthematous pustulosis (AGEP) is a rare exanthem characterized by the abrupt onset of numerous small, non-follicular, sterile pustules arising on an erythematous base."1.56Delayed Presentation of Acute Generalized Exanthematous Pustulosis Following Treatment with Cefepime in a Patient with COVID-19 without the Use of Hydroxychloroquine. ( Haraszti, S; Jensen, N; Sendil, S, 2020)
"Hydroxychloroquine (HCQ) is an antimalarial drug that is also used in some dermatologic and rheumatic diseases due to its immunosuppressive actions."1.51The First Pediatric Case of Acute Generalized Exanthematous Pustulosis Caused by Hydroxychloroquine. ( Barni, S; Giani, T; Liccioli, G; Marrani, E; Mori, F; Simonini, G, 2019)
"Hydroxychloroquine has a particularly long half-life and is a known cause of AGEP; therefore, it is possible that HCQ-induced AGEP may not follow the typical rapid recovery time."1.43Prolonged pustular eruption from hydroxychloroquine: an unusual case of acute generalized exanthematous pustulosis. ( Jolly, P; Morrell, DS; Pearson, KC; Runge, SR, 2016)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (20.00)24.3611
2020's24 (80.00)2.80

Authors

AuthorsStudies
Wang, G1
Zhuo, N1
Li, J1
Demircioğlu, D1
Karabıyık, N1
Durmaz, EÖ1
Demirkesen, C1
Şahin, S1
Odorici, G1
Schenetti, C1
Pacetti, L1
Schettini, N1
Gaban, A1
Mantovani, L1
Yan, C1
Shang, Q1
Geng, S1
Tsurane, K3
Kaneko, K3
Yoshida, K3
Tanaka, R3
Sago, H3
Murashima, A3
Novruzov, E2
Schmitt, D2
Mori, Y2
Kirchner, J2
Kobbe, G2
Reifenberger, J2
Mamlins, E2
Antke, C2
Giesel, FL2
Al Muqarrab, F1
Schwartz, RA2
Almohssen, AA1
Luo, F1
Yuan, XM1
Xiong, H1
Chen, CM1
Ma, WK1
Yao, XM1
Matsuda-Hirose, H1
Sho, Y1
Yamate, T1
Nakamura, Y1
Saito, K1
Takeo, N1
Nishida, H1
Ishii, K1
Sugiura, K1
Hatano, Y1
Janniger, CK1
Robustelli Test, E1
Vezzoli, P1
Carugno, A1
Raponi, F1
Gianatti, A1
Rongioletti, F1
Sena, P1
Litaiem, N1
Hajlaoui, K1
Karray, M1
Slouma, M1
Zeglaoui, F1
Delaleu, J1
Deniau, B1
Battistella, M1
de Masson, A1
Bensaid, B1
Jachiet, M1
Lazaridou, I1
Bagot, M1
Bouaziz, JD1
Enos, T1
Jeong, HS1
Vandergriff, T1
Jacobe, HT1
Chong, BF1
Kuraitis, D1
Murina, A1
Otake-Irie, H1
Nakajima, S1
Okamoto, N1
Toichi, E1
Nomura, T1
Kabashima, K1
Nili, A1
Zarei, E1
Ghamari, A1
Farid, AS1
Tavakolpour, S1
Daneshpazhooh, M1
Mahmoudi, H1
Haraszti, S1
Sendil, S1
Jensen, N1
Coleman, I1
Ruiz, G1
Brahmbhatt, S1
Ackerman, L1
Mofarrah, R2
Oshriehye, M1
Ghobadi Aski, S1
Nazemi, N1
Nooshiravanpoor, P1
Chaabouni, R1
Bahloul, E1
Ennouri, M1
Atheymen, R1
Sellami, K1
Marrakchi, S1
Charfi, S1
Boudaya, S1
Amouri, M1
Bougacha, N1
Turki, H1
Kantor, J1
Atak, MF1
Farabi, B1
Akbayrak, A1
Kalelioğlu, MB1
Rao, BK1
Hsieh, CH1
Yao, CA1
Lo, Y1
Castner, NB1
Harris, JC1
Motaparthi, K1
Liccioli, G1
Marrani, E1
Giani, T1
Simonini, G1
Barni, S1
Mori, F1
Pastushenko, I1
Gracia-Cazaña, T1
Morales-Moya, AL1
Grasa, MP1
Zhang, Z1
Liu, X1
Pearson, KC1
Morrell, DS1
Runge, SR1
Jolly, P1
Djennane, M1
Tablit, I1
Billhot, M1
Banal, F1

Reviews

4 reviews available for hydroxychloroquine and Acute Generalised Exanthematous Pustulosis

ArticleYear
Generalized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review.
    Acta dermatovenerologica Croatica : ADC, 2022, Volume: 30, Issue:4

    Topics: Acute Generalized Exanthematous Pustulosis; COVID-19; COVID-19 Drug Treatment; Erythema; Humans; Hyd

2022
Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine.
    Dermatologic therapy, 2020, Volume: 33, Issue:3

    Topics: Acute Generalized Exanthematous Pustulosis; Adrenal Cortex Hormones; Coronavirus Infections; COVID-1

2020
Hydroxychloroquine-induced acute generalized exanthematous pustulosis: a series of seven patients and review of the literature.
    International journal of dermatology, 2021, Volume: 60, Issue:6

    Topics: Acute Generalized Exanthematous Pustulosis; Exanthema; Female; Humans; Hydroxychloroquine; Interleuk

2021
Cyclosporine for corticosteroid-refractory acute generalized exanthematous pustulosis due to hydroxychloroquine.
    Dermatologic therapy, 2018, Volume: 31, Issue:5

    Topics: Acute Generalized Exanthematous Pustulosis; Cyclosporine; Dermatologic Agents; Female; Glucocorticoi

2018

Other Studies

26 other studies available for hydroxychloroquine and Acute Generalised Exanthematous Pustulosis

ArticleYear
Acute generalized exanthematous pustulosis induced by generic hydroxychloroquine.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:8

    Topics: Acute Generalized Exanthematous Pustulosis; Humans; Hydroxychloroquine

2022
AGEP sine pustulosis induced by hydroxychloroquine used for COVID-19 infection.
    Dermatologic therapy, 2022, Volume: 35, Issue:3

    Topics: Acute Generalized Exanthematous Pustulosis; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; SAR

2022
Acute generalized exanthematous pustulosis due to hydroxichloroquine.
    Dermatologic therapy, 2022, Volume: 35, Issue:7

    Topics: Acute Generalized Exanthematous Pustulosis; Humans; Hydroxychloroquine

2022
Hydroxychloroquine-induced acute generalized exanthematous pustulosis in an orofacial granulomatosis patient with homozygous IL36RN mutation.
    Dermatologic therapy, 2022, Volume: 35, Issue:8

    Topics: Acute Generalized Exanthematous Pustulosis; Granulomatosis, Orofacial; Homozygote; Humans; Hydroxych

2022
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.
    Modern rheumatology case reports, 2023, 06-19, Volume: 7, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Cesarean Section; Child; Di

2023
Unique [
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:5

    Topics: Acute Generalized Exanthematous Pustulosis; Fluorodeoxyglucose F18; Humans; Hydroxychloroquine

2023
Unique [
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:5

    Topics: Acute Generalized Exanthematous Pustulosis; Fluorodeoxyglucose F18; Humans; Hydroxychloroquine

2023
Unique [
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:5

    Topics: Acute Generalized Exanthematous Pustulosis; Fluorodeoxyglucose F18; Humans; Hydroxychloroquine

2023
Unique [
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:5

    Topics: Acute Generalized Exanthematous Pustulosis; Fluorodeoxyglucose F18; Humans; Hydroxychloroquine

2023
Acute generalized exanthematous pustulosis caused by hydroxychloroquine in a patient with rheumatoid arthritis and CARD14 mutation: Case report.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Arthritis, Rheumatoid; CARD Signaling Adaptor Pro

2023
Acute generalized exanthematous pustulosis induced by hydroxychloroquine successfully treated with etretinate.
    The Journal of dermatology, 2020, Volume: 47, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Biopsy; Etretinate; Female;

2020
Acute generalized exanthematous pustulosis with erythema multiforme-like lesions induced by Hydroxychloroquine in a woman with coronavirus disease 2019 (COVID-19).
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:9

    Topics: Acute Generalized Exanthematous Pustulosis; Aged; COVID-19; COVID-19 Drug Treatment; Female; Humans;

2020
Acute generalized exanthematous pustulosis after COVID-19 treatment with hydroxychloroquine.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Acute Generalized Exanthematous Pustulosis; Betacoronavirus; Chemoprevention; Coronavirus Infections

2020
Acute generalized exanthematous pustulosis induced by hydroxychloroquine prescribed for COVID-19.
    The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:8

    Topics: Acute Generalized Exanthematous Pustulosis; Aged; Antirheumatic Agents; Betacoronavirus; Coronavirus

2020
Acute generalized exanthematous pustulosis induced by empiric hydroxychloroquine for presumed COVID-19.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antiviral Agents; COVID-19; COVID-19 Drug Treatme

2020
Facts, not Fear: Safety of Hydroxychloroquine.
    The American journal of the medical sciences, 2020, Volume: 360, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Agranulocytosis; Anemia, Aplastic; Antirheumatic Agents;

2020
Prolonged acute generalized exanthematous pustulosis and atypical target-like lesions induced by hydroxychloroquine.
    The Journal of dermatology, 2020, Volume: 47, Issue:11

    Topics: Acute Generalized Exanthematous Pustulosis; Antirheumatic Agents; Humans; Hydroxychloroquine

2020
Acute generalized exanthematous pustulosis with a focus on hydroxychloroquine: A 10-year experience in a skin hospital.
    International immunopharmacology, 2020, Volume: 89, Issue:Pt B

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Aged; Female; Humans; Hydroxychloroquine; Male; M

2020
Delayed Presentation of Acute Generalized Exanthematous Pustulosis Following Treatment with Cefepime in a Patient with COVID-19 without the Use of Hydroxychloroquine.
    The American journal of case reports, 2020, Oct-24, Volume: 21

    Topics: Acute Generalized Exanthematous Pustulosis; Aged; Betacoronavirus; Biopsy; Coronavirus Infections; C

2020
Acute generalized exanthematous pustulosis and Stevens-Johnson syndrome overlap due to hydroxychloroquine: a case report.
    Journal of medical case reports, 2020, Nov-03, Volume: 14, Issue:1

    Topics: Acute Generalized Exanthematous Pustulosis; Aged; Antimalarials; Biopsy; Coronavirus Infections; COV

2020
The necessity of patch testing in determining the causative drug of AGEP.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:7

    Topics: Acute Generalized Exanthematous Pustulosis; Female; Humans; Hydroxychloroquine; Middle Aged; Patch T

2021
June 2021: Acute generalized exanthematous pustulosis in Asia.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:6

    Topics: Acute Generalized Exanthematous Pustulosis; Asia; Humans; Hydroxychloroquine

2021
Acute generalized exanthematous pustulosis following treatment with favipiravir in a patient with COVID-19 without hydroxychloroquine use: Report of the first case.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:8

    Topics: Acute Generalized Exanthematous Pustulosis; Amides; COVID-19 Drug Treatment; Humans; Hydroxychloroqu

2021
Acute generalized exanthematous pustulosis induced by hydroxychloroquine.
    The Kaohsiung journal of medical sciences, 2021, Volume: 37, Issue:12

    Topics: Acute Generalized Exanthematous Pustulosis; Female; Humans; Hydroxychloroquine; Middle Aged

2021
The First Pediatric Case of Acute Generalized Exanthematous Pustulosis Caused by Hydroxychloroquine.
    Pharmacology, 2019, Volume: 104, Issue:1-2

    Topics: Acute Generalized Exanthematous Pustulosis; Antirheumatic Agents; Child; Female; Histamine Antagonis

2019
[Acute cutaneous pustular eruption due to hydroxychloroquine].
    Medicina clinica, 2014, Oct-07, Volume: 143, Issue:7

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; Antirheumatic Agents; Female; Humans; Hydroxychlo

2014
Images in clinical medicine. Acute generalized exanthematous pustulosis.
    The New England journal of medicine, 2015, Jan-08, Volume: 372, Issue:2

    Topics: Acute Generalized Exanthematous Pustulosis; Female; Humans; Hydroxychloroquine; Middle Aged; Sjogren

2015
Prolonged pustular eruption from hydroxychloroquine: an unusual case of acute generalized exanthematous pustulosis.
    Cutis, 2016, Volume: 97, Issue:3

    Topics: Acute Generalized Exanthematous Pustulosis; Antirheumatic Agents; Female; Half-Life; Humans; Hydroxy

2016
[Acute generalized exanthematic pustulosis induced by hydroxychloroquine: case report].
    La Revue de medecine interne, 2010, Volume: 31, Issue:3

    Topics: Acute Generalized Exanthematous Pustulosis; Antirheumatic Agents; Diagnosis, Differential; Female; H

2010