hydroxychloroquine has been researched along with ATLL in 1 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult T-cell leukemia/lymphoma (ATLL) originates from human T-cell leukemia virus type 1 (HTLV-1) infection due to the activation of the nuclear factor-κB (NF-κB) signaling pathway to maintain proliferation and survival." | 1.62 | Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells. ( Chilmi, S; Fauzi, YR; Ichikawa, T; Morishita, K; Nakahata, S; Nakamura, T; Nueangphuet, P; Shimoda, K; Yamaguchi, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fauzi, YR | 1 |
| Nakahata, S | 1 |
| Chilmi, S | 1 |
| Ichikawa, T | 1 |
| Nueangphuet, P | 1 |
| Yamaguchi, R | 1 |
| Nakamura, T | 1 |
| Shimoda, K | 1 |
| Morishita, K | 1 |
1 other study available for hydroxychloroquine and ATLL
| Article | Year |
|---|---|
Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Gene Expression Regulation, Leukemic; | 2021 |