hydroxyaniline mustard has been researched along with Colorectal Neoplasms in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blakey, DC; Boyle, FT; Burke, PJ; Connors, TA; Davies, DH; Dowell, RI; Hadley, EM; Mauger, AB; Melton, RG; Springer, CJ | 1 |
| Davies, L; Friedlos, F; Marais, R; Martin, J; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Spooner, R; Springer, CJ | 1 |
| Begent, RH; Bell, J; Boxer, GM; Chester, KA; Cruickshank, C; Francis, RJ; Green, AJ; Hartley, JA; Martin, J; Mayer, A; Sharma, SK; Springer, CJ; Tolner, B; Wren, J | 1 |
| Blakey, DC; Burke, PJ; Davies, DH; Dowell, RI; East, SJ; Mauger, AB; Melton, RG; Sharma, SK; Springer, CJ | 1 |
1 trial(s) available for hydroxyaniline mustard and Colorectal Neoplasms
| Article | Year |
|---|---|
A phase I study of single administration of antibody-directed enzyme prodrug therapy with the recombinant anti-carcinoembryonic antigen antibody-enzyme fusion protein MFECP1 and a bis-iodo phenol mustard prodrug.
Topics: Aged; Aniline Mustard; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoembryonic Antigen; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; gamma-Glutamyl Hydrolase; History, 16th Century; History, 17th Century; Humans; Imaging, Three-Dimensional; Immunoconjugates; Male; Prodrugs; Recombinant Fusion Proteins | 2006 |
3 other study(ies) available for hydroxyaniline mustard and Colorectal Neoplasms
| Article | Year |
|---|---|
New mustard prodrugs for antibody-directed enzyme prodrug therapy: alternatives to the amide link.
Topics: Aniline Mustard; Antineoplastic Agents; Cell Death; Cell Division; Colorectal Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunotoxins; Molecular Structure; Prodrugs; Tumor Cells, Cultured | 1996 |
Self-immolative nitrogen mustard prodrugs for suicide gene therapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Drug Screening Assays, Antitumor; gamma-Glutamyl Hydrolase; Genetic Therapy; Inhibitory Concentration 50; Mechlorethamine; Mice; Mutation; Prodrugs; Transfection; Tumor Cells, Cultured | 1998 |
Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs.
Topics: Aniline Mustard; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents, Alkylating; Bacterial Proteins; Biotransformation; Carcinoembryonic Antigen; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Female; gamma-Glutamyl Hydrolase; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Mice; Mice, Nude; Neoplasm Transplantation; Prodrugs; Pseudomonas; Substrate Specificity; Tumor Cells, Cultured | 1995 |