hydroxyacetylaminofluorene has been researched along with Liver Neoplasms in 12 studies
Hydroxyacetylaminofluorene: A N-hydroxylated derivative of 2-ACETYLAMINOFLUORENE that has demonstrated carcinogenic action.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the role of dosing regimen on ras mutations in chemically induced CD-1 mouse liver tumors." | 1.29 | Dose-related changes in the profile of ras mutations in chemically induced CD-1 mouse liver tumors. ( Hammermeister, CL; Joslyn, DJ; Kraynak, AR; Leander, KR; Ledwith, BJ; Manam, S; Nichols, WW; Prahalada, S; Shinder, GA; van Zwieten, MJ, 1995) |
| "Male Spraque-Dawley rats were 6 or 7 times more susceptible than females to the acute toxic effects of a single i." | 1.25 | Comparative toxicity of N-hydroxy-2-acetylaminofluorene in several strains of rats. ( Irving, CC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobs, MM | 1 |
| Beland, FA | 1 |
| Dooley, KL | 1 |
| Jackson, CD | 1 |
| Flaks, B | 1 |
| Yost, Y | 1 |
| Flaks, A | 1 |
| Manam, S | 2 |
| Shinder, GA | 1 |
| Joslyn, DJ | 2 |
| Kraynak, AR | 1 |
| Hammermeister, CL | 1 |
| Leander, KR | 2 |
| Ledwith, BJ | 2 |
| Prahalada, S | 2 |
| van Zwieten, MJ | 2 |
| Nichols, WW | 2 |
| Troilo, P | 1 |
| Clair, JH | 1 |
| Soper, KA | 1 |
| Becker, FF | 2 |
| Stout, DL | 1 |
| Farber, E | 1 |
| Solt, D | 1 |
| Cameron, R | 1 |
| Laishes, B | 1 |
| Ogawa, K | 1 |
| Medline, A | 1 |
| Irving, CC | 1 |
| Meerman, JH | 1 |
| Lai, CC | 2 |
| Miller, EC | 2 |
| Miller, JA | 2 |
| Liem, A | 2 |
| Boberg, EW | 1 |
| Delclos, KB | 1 |
| Fennell, TR | 1 |
| Wiseman, RW | 1 |
1 review available for hydroxyacetylaminofluorene and Liver Neoplasms
| Article | Year |
|---|---|
Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver.
Topics: 2-Acetylaminofluorene; Animals; Azo Compounds; Biotransformation; Carcinogens; Chemical Phenomena; C | 1985 |
11 other studies available for hydroxyacetylaminofluorene and Liver Neoplasms
| Article | Year |
|---|---|
Effects of selenium on chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Butylated Hydroxytolue | 1980 |
Persistence of DNA adducts in rat liver and kidney after multiple doses of the carcinogen N-hydroxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; DNA; Female; Hydroxyacetylaminofluorene; Kidney; Liver; Liver Neopla | 1982 |
Effects of prolonged oral treatment with N-fluoren-4-ylacetohydroxamic acid on rat liver fine structure.
Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carcinogens; Endoplasmic Reticulum; Hydroxyace | 1982 |
Dose-related changes in the profile of ras mutations in chemically induced CD-1 mouse liver tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Codon; Diethylnitrosamine; DNA, Neo | 1995 |
Induction of minisatellite DNA rearrangements by genotoxic carcinogens in mouse liver tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Diethylnitrosamine; DNA | 1995 |
Alteration of hepatocytes by subcarcinogenic exposure to n-2-fluorenylacetamide.
Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Chromosome Aberrations; Diet; Dimethylnitrosamine; | 1975 |
Alteration of the ability of liver microsomes to activate N-2-fluorenylacetamide to a mutagen of Salmonella typhimurium during hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Fluorenes; Hydroxyacetylaminofluorene; Li | 1978 |
Newer insights into the pathogenesis of liver cancer.
Topics: Aflatoxins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnit | 1977 |
Comparative toxicity of N-hydroxy-2-acetylaminofluorene in several strains of rats.
Topics: Animals; Female; Fluorenes; Hydroxyacetylaminofluorene; Lethal Dose 50; Liver; Liver Neoplasms; Male | 1975 |
The initiation of gamma-glutamyltranspeptidase positive foci in the rat liver by N-hydroxy-2-acetylaminofluorene. The effect of the sulfation inhibitor pentachlorophenol.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chlorophenols; Enzyme Induction; gamma-Glutamyltransfer | 1985 |
The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice.
Topics: 2-Acetylaminofluorene; Amidohydrolases; Animals; Animals, Newborn; Biotransformation; Cytosol; DNA D | 1988 |