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hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester and Sarcoma, Kaposi

hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester has been researched along with Sarcoma, Kaposi in 1 studies

hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester : An organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation.

Sarcoma, Kaposi: A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rose, PP1
Carroll, JM1
Carroll, PA1
DeFilippis, VR1
Lagunoff, M1
Moses, AV1
Roberts, CT1
Früh, K1

Other Studies

1 other study available for hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester and Sarcoma, Kaposi

ArticleYear
The insulin receptor is essential for virus-induced tumorigenesis of Kaposi's sarcoma.
    Oncogene, 2007, Mar-29, Volume: 26, Issue:14

    Topics: Cell Line, Transformed; Cell Transformation, Viral; Endothelial Cells; Herpesvirus 8, Human; Humans;

2007