hydroxocobalamin and Syndrome

hydroxocobalamin has been researched along with Syndrome* in 3 studies

Trials

1 trial(s) available for hydroxocobalamin and Syndrome

Article	Year
Controlled trial of combinations of hydroxocobalamin-cystine and riboflavine-cystine, in Nigerian ataxic neuropathy. Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:1 Chronic cyanide intoxication of dietary origin and riboflavine deficiency are believed to be major aetiological factors in Nigerian tropical ataxic neuropathy. The results are presented of a double-blind controlled therapeutic trial of combinations of large doses of hydroxocobalamin and cystine as cyanide binding agents together with riboflavine or placebos in Nigerian patients suffering from the tropical ataxic neuropathy. No clinical benefit was demonstrable with any of the treatments. Topics: Ataxia; Cyanides; Cystine; Deafness; Evaluation Studies as Topic; Female; Humans; Hydroxocobalamin; Male; Middle Aged; Nigeria; Optic Atrophy; Peripheral Nervous System Diseases; Placebos; Poisoning; Riboflavin; Riboflavin Deficiency; Syndrome; Thiocyanates; Vitamin B 12	1974

Article

Year

Controlled trial of combinations of hydroxocobalamin-cystine and riboflavine-cystine, in Nigerian ataxic neuropathy.

Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:1

Chronic cyanide intoxication of dietary origin and riboflavine deficiency are believed to be major aetiological factors in Nigerian tropical ataxic neuropathy. The results are presented of a double-blind controlled therapeutic trial of combinations of large doses of hydroxocobalamin and cystine as cyanide binding agents together with riboflavine or placebos in Nigerian patients suffering from the tropical ataxic neuropathy. No clinical benefit was demonstrable with any of the treatments.

Topics: Ataxia; Cyanides; Cystine; Deafness; Evaluation Studies as Topic; Female; Humans; Hydroxocobalamin; Male; Middle Aged; Nigeria; Optic Atrophy; Peripheral Nervous System Diseases; Placebos; Poisoning; Riboflavin; Riboflavin Deficiency; Syndrome; Thiocyanates; Vitamin B 12

1974

Other Studies

2 other study(ies) available for hydroxocobalamin and Syndrome

Article	Year
West Indian amblyopia. Postgraduate medical journal, 1980, Volume: 56, Issue:657 A series of 21 patients admitted to St Thomas' Hospital, Medical Ophthalmology Unit, with a diagnosis of West Indian or West African amblyopia is reported. Patients were investigated for haematological, biochemical, serological, and radiological abnormalities and particular attention was paid to dietary history. Patients admitted in recent years also underwent neurophysiological investigations. No definite correlation between visual loss and dietary or family history was found, and there was no evidence that the improvement in vision which occurred in just under half the patients on follow-up was related to treatment with hydroxocobalamin or multivitamins. Visual-evoked responses in 4 patients showed a prolonged latency suggesting optic nerve demyelination, while in only one case was the electro-oculogram definitely subnormal. These findings contrast with those in 'toxic' amblyopias and suggest that the syndrome of West Indian amblyopoa may be due to bilateral optic nerve demyelination of unknown aetiology rather than the effect of toxic substances or nutritional deficiency on the retina. Topics: Adolescent; Africa, Western; Amblyopia; Child; Demyelinating Diseases; Diet; Female; Humans; Hydroxocobalamin; London; Male; Middle Aged; Nutrition Disorders; Syndrome; West Indies	1980
[On the treatment of neurological syndromes with large doses of hydroxocobalamin. Clinical and experimental data]. Minerva medica, 1962, Dec-19, Volume: 53 Topics: Humans; Hydroxocobalamin; Neurology; Syndrome	1962

Article

Year

West Indian amblyopia.

Postgraduate medical journal, 1980, Volume: 56, Issue:657

A series of 21 patients admitted to St Thomas' Hospital, Medical Ophthalmology Unit, with a diagnosis of West Indian or West African amblyopia is reported. Patients were investigated for haematological, biochemical, serological, and radiological abnormalities and particular attention was paid to dietary history. Patients admitted in recent years also underwent neurophysiological investigations. No definite correlation between visual loss and dietary or family history was found, and there was no evidence that the improvement in vision which occurred in just under half the patients on follow-up was related to treatment with hydroxocobalamin or multivitamins. Visual-evoked responses in 4 patients showed a prolonged latency suggesting optic nerve demyelination, while in only one case was the electro-oculogram definitely subnormal. These findings contrast with those in 'toxic' amblyopias and suggest that the syndrome of West Indian amblyopoa may be due to bilateral optic nerve demyelination of unknown aetiology rather than the effect of toxic substances or nutritional deficiency on the retina.

Topics: Adolescent; Africa, Western; Amblyopia; Child; Demyelinating Diseases; Diet; Female; Humans; Hydroxocobalamin; London; Male; Middle Aged; Nutrition Disorders; Syndrome; West Indies

1980

[On the treatment of neurological syndromes with large doses of hydroxocobalamin. Clinical and experimental data].

Minerva medica, 1962, Dec-19, Volume: 53

Topics: Humans; Hydroxocobalamin; Neurology; Syndrome

1962