hydroxocobalamin has been researched along with Critical-Illness* in 3 studies
3 other study(ies) available for hydroxocobalamin and Critical-Illness
| Article | Year |
|---|---|
Hydroxocobalamin With or Without Methylene Blue May Improve Fluid Balance in Critically Ill Patients With Vasoplegic Syndrome After Cardiac Surgery: A Report of Two Cases.
Topics: Adult; Cardiac Surgical Procedures; Critical Illness; Humans; Hydroxocobalamin; Male; Methylene Blue; Vasoplegia; Water-Electrolyte Balance | 2018 |
Risk of oxalate nephropathy with the use of cyanide antidote hydroxocobalamin in critically ill burn patients.
Topics: Acute Kidney Injury; Adult; Burns; Calcium Oxalate; Critical Illness; Humans; Hydroxocobalamin; Male; Middle Aged; Respiration, Artificial; Smoke Inhalation Injury | 2016 |
Use of vitamin B12 in the treatment and prevention of nitroprusside-induced cyanide toxicity.
To review the mechanism of action, safety, and efficacy of hydroxocobalamin in the treatment and prevention of nitroprusside-induced cyanide toxicity.. English and foreign-language journal articles and reference texts identified from Index Medicus. Both animal and human studies were included.. High-dose or prolonged therapy with nitroprusside in patients with hepatic or renal dysfunction increases the risk for nitroprusside-induced cyanide or thiocyanate toxicity, respectively. Hydroxocobalamin has been shown to significantly reduce RBC and plasma cyanide concentrations in animals and surgical patients without producing clinically important adverse effects or toxic metabolites. Thiosulfate infusions also decrease cyanide toxicity but can cause accumulation of thiocyanate resulting in clinical toxicity. Cyanocobalamin cannot effectively remove cyanide due to poor binding.. Hydroxocobalamin is a safe and effective agent in the prevention and treatment of nitroprusside-induced cyanide toxicity. Prolonged or high-dose infusions of nitroprusside should be minimized in critically ill patients, especially if hepatic and/or renal dysfunction is present. Topics: Animals; Critical Illness; Cyanides; Humans; Hydroxocobalamin; Hypertension; Nitroprusside; Poisoning | 1993 |