hydroxocobalamin and Anemia

hydroxocobalamin has been researched along with Anemia* in 23 studies

Reviews

2 review(s) available for hydroxocobalamin and Anemia

ArticleYear
Prophylaxis and treatment of anaemia during pregnancy.
    Clinics in obstetrics and gynaecology, 1981, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Female; Ferritins; Ferrous Compounds; Folic Acid; Folic Acid Deficiency; Humans; Hydroxocobalamin; Iron; Middle Aged; Pregnancy; Pregnancy Complications, Hematologic; Vitamin B 12 Deficiency

1981
[Treatment of deficiency anemias].
    Deutsches medizinisches Journal, 1968, Jun-20, Volume: 19, Issue:12

    Topics: Anemia; Anemia, Aplastic; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Anemia, Sideroblastic; Ascorbic Acid Deficiency; Avitaminosis; Blood Protein Disorders; Hormones; Humans; Hydroxocobalamin; Vitamins

1968

Other Studies

21 other study(ies) available for hydroxocobalamin and Anemia

ArticleYear
Nephrotic syndrome and thrombotic microangiopathy caused by cobalamin C deficiency.
    Pediatric nephrology (Berlin, Germany), 2015, Volume: 30, Issue:7

    Cobalamin C (CblC) defects are inherited autosomal recessive disorders of vitamin B12 metabolism due to mutations in the MMACHC gene. Renal manifestations include thrombotic microangiopathy (TMA), acute or chronic renal failure, tubulointerstitial nephritis, and proximal renal tubular acidosis. However, reports about glomerular pathologies are scarce.. A 4-year-old boy presented with nephrotic syndrome, arterial hypertension, and chronic anemia but no signs of hemolysis. Renal biopsy showed TMA with ischemic glomerular collapse, foot process effacement, and tubulointerstitial fibrosis. Elevated serum levels of homocysteine suggested a cobalamin C disorder. This was confirmed by the identification of compound heterozygous mutations in the MMACHC gene. Initial therapy consisted of antihypertensive treatment including angiotensin converting enzyme inhibitor (ACEi) leading to blood pressure control and a significant reduction of proteinuria. After a definite diagnosis of CblC deficiency, hydroxocobalamin was introduced. Thereafter, homocysteine levels decreased, anemia resolved, and a further decline of proteinuria with normalization of serum protein levels was noted. Renal function remained stable.. Although uncommon, the clinical picture of CblC defects may be ruled by nephrotic syndrome mimicking glomerulonephritis, minimal change disease, or primary focal and segmental glomerulosclerosis. Key to a correct diagnosis is elevated serum levels of homocysteine, and a definite diagnosis can be confirmed by genetic testing.

    Topics: Anemia; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Carrier Proteins; Child, Preschool; Homocysteine; Humans; Hydroxocobalamin; Hypertension, Renal; Kidney; Male; Nephrotic Syndrome; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency

2015
Late-onset thrombocytic microangiopathy caused by cblC disease: association with a factor H mutation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:3

    cblC disease is a cause of hemolytic uremic syndrome (HUS), which has been primarily described in neonates and infants with severe renal and neurological lesions.. Two sisters aged 6 and 8.5 years presented with a latent hemolytic process characterized by undetectable or low plasma haptoglobin, respectively, associated with renal failure and gross proteinuria. Renal biopsies performed in both patients found typical findings of thrombotic microangiopathy suggesting the diagnosis of HUS. Both patients were free of neurologic signs.. Biochemical investigations found a cobalamin processing deficiency of the cblC type. Search for additional factors susceptible to worsen endothelial damage revealed homozygosity 677C--> T mutation in the methylenetetrahydrofolate reductase gene as well as heterozygosity for a 3254T--> C mutation in factor H in the patient with the most severe clinical presentation. Long-term subcutaneous administration of hydroxocobalamin in combination with oral betaine and folic acid resulted in clinical and biological improvement in both patients.. cblC disease may be a cause of chronic HUS with delayed onset in childhood. Superimposed mutation of factor H gene might influence clinical severity.

    Topics: Anemia; Betaine; Child; Combined Modality Therapy; Complement Factor H; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Haptoglobins; Hemolytic-Uremic Syndrome; Humans; Hydroxocobalamin; Hypertension; Kidney; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Nephrotic Syndrome; Plasma Exchange; Point Mutation; Proteinuria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Renal Dialysis; Vitamin B 12

2005
Vitamin B-12 abnormalities in HIV-infected patients.
    European journal of haematology, 1991, Volume: 47, Issue:1

    A prospective study of 60 consecutively admitted patients with HIV infection was performed to document the prevalence, etiology and manifestations of low serum vitamin B-12 in such patients. Low serum B-12 levels were found in 10 patients (16.7%). In 6, vitamin B-12 absorption was impaired and hog intrinsic factor addition did not improve it. Patients with low vitamin B-12 levels showed lower hemoglobin, leukocytes, lymphocytes, CD4 lymphocytes and CD4/CD8 lymphocyte ratio than HIV patients with physiological serum vitamin B-12 levels. However, bone marrow megaloblastosis was found in only 3 low vitamin B-12 patients and the deoxyuridine suppression test was pathological in only 1 case. In 7 patients, parenteral treatment was begun with variable response despite serum vitamin B-12 correction. In conclusion, low serum vitamin B-12 is often found in HIV-infected patients and it could be related to malabsorption, but clear megaloblastic abnormalities and treatment response could not be demonstrated. A decreased concentration of the serum binders due to disturbances in the leukocytes and related immunocompetent cell may play an additional role.

    Topics: Adult; Anemia; Female; Gastric Acid; HIV Infections; Humans; Hydroxocobalamin; Intrinsic Factor; Leukocyte Count; Male; Prospective Studies; Vitamin B 12

1991
Anaemia in the elderly.
    British medical journal, 1973, Nov-03, Volume: 4, Issue:5887

    Topics: Aged; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Blood Transfusion; Diet; Female; Folic Acid; Folic Acid Deficiency; Humans; Hydroxocobalamin; Iron; Male; Middle Aged; Vitamin B 12 Deficiency

1973
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; Herpes Zoster; Humans; Hydroxocobalamin; Joint Diseases; Male; Middle Aged; Myelitis; Nervous System Diseases; Nutrition Disorders; Optic Neuritis; Polyneuropathies; Psychoses, Alcoholic; Pyridoxine; Sciatica; Thiamine

1968
[On coenzyme B 12. II. Pharmacological aspects].
    Bollettino chimico farmaceutico, 1967, Volume: 106, Issue:3

    Topics: Anemia; Animals; Coenzymes; Dogs; Hydroxocobalamin; Liver; Male; Rabbits; Rats; Vitamin B 12

1967
CHRONIC ERYTHROCYTIC HYPOPLASIA FOLLOWING PERNICIOUS ANEMIA.
    Blood, 1965, Volume: 25

    Topics: Anemia; Anemia, Aplastic; Anemia, Pernicious; Blood Transfusion; Bone Marrow Examination; Clinical Laboratory Techniques; Cobalt; Drug Therapy; Erythrocytes; Humans; Hydroxocobalamin; Prednisone; Pyridoxine; Riboflavin; Testosterone; Vitamin B 12

1965
HYDROXOCOBALAMIN: EXCRETION AND RETENTION AFTER PARENTERAL DOSES IN ANEMIC AND NONANEMIC SUBJECTS, WITH REFERENCE TO THE TREATMENT OF VITAMIN B12 DEFICIENCY STATES.
    The Journal of laboratory and clinical medicine, 1965, Volume: 65

    Topics: Anemia; Anemia, Macrocytic; Cobalt Isotopes; Drug Therapy; Fluids and Secretions; Humans; Hydroxocobalamin; Metabolism; Urine; Vitamin B 12; Vitamin B 12 Deficiency

1965
[ON LONG-TERM THERAPY OF PERNICIOUS ANEMIA WITH HYDROXOCOBALAMIN].
    Wiener medizinische Wochenschrift (1946), 1965, Jan-16, Volume: 115

    Topics: Anemia; Anemia, Pernicious; Delayed-Action Preparations; Drug Therapy; Hematinics; Humans; Hydroxocobalamin; Vitamin B 12

1965
[ON HYDROXOCOBALAMIN THERAPY].
    Wiener medizinische Wochenschrift (1946), 1965, May-22, Volume: 115

    Topics: Anemia; Anemia, Macrocytic; Drug Therapy; Humans; Hydroxocobalamin

1965
HYDROXOCOBALAMIN AND CYANOCOBALAMIN IN ADDISONIAN ANAEMIA.
    Lancet (London, England), 1964, Jan-04, Volume: 1, Issue:7323

    Topics: Anemia; Anemia, Pernicious; Blood Chemical Analysis; Hematinics; Humans; Hydroxocobalamin; Urine; Vitamin B 12

1964
[NEURO-ANEMIA SYNDROME].
    Le Progres medical, 1964, Jan-10, Volume: 92

    Topics: Anemia; Anemia, Pernicious; Corrinoids; Folic Acid; Hematinics; Humans; Hydrochloric Acid; Hydroxocobalamin; Liver Extracts; Perception; Stomach; Tissue Extracts; Vitamin B 12

1964
[RETENTION OF VITAMIN B12. A COMPARATIVE STUDY OF RETENTION AFTER INTRAMUSCULAR INJECTION OF CYANOCOBALAMIN AND HYDROOXOCOBALAMIN RESPECTIVELY].
    Ugeskrift for laeger, 1964, Apr-16, Volume: 126

    Topics: Anemia; Anemia, Pernicious; Blood Chemical Analysis; Creatine; Creatinine; Humans; Hydroxocobalamin; Injections; Injections, Intramuscular; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

1964
[CASE OF PERNICIOUS ANEMIA TREATED WITH HYDROXOCOBALAMIN].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Anemia; Anemia, Pernicious; Blood Chemical Analysis; Erythrocyte Count; Geriatrics; Humans; Hydroxocobalamin

1964
HYDROXOCOBALAMIN FOR PERNICIOUS ANAEMIA.
    Lancet (London, England), 1964, Jul-25, Volume: 2, Issue:7352

    Topics: Anemia; Anemia, Pernicious; Drug Therapy; Hematinics; Humans; Hydroxocobalamin; Vitamin B 12

1964
STUDIES ON VITAMIN B12 RETENTION. COMPARISON OF RETENTION FOLLOWING INTRAMUSCULAR INJECTION OF CYANOCOBALAMIN AND HYDROXOCOBALAMIN.
    Scandinavian journal of haematology, 1964, Volume: 1

    Topics: Anemia; Anemia, Pernicious; Blood Chemical Analysis; Blood Proteins; Corrinoids; Humans; Hydroxocobalamin; Injections, Intramuscular; Metabolism; Urine; Vitamin B 12

1964
[HYDROXOCOBEMIN TREATMENT OF PERNICIOUS ANEMIA].
    Ugeskrift for laeger, 1964, Oct-01, Volume: 126

    Topics: Anemia; Anemia, Pernicious; Drug Therapy; Humans; Hydroxocobalamin

1964
[Treatment of Biermer's disease with hydroxocobalamin].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1963, Jun-20, Volume: 39

    Topics: Anemia; Anemia, Pernicious; Humans; Hydroxocobalamin; Tracheophyta

1963
[A new administration form of vitamin B12: hydroxycobalamin].
    La Presse medicale, 1963, Jan-26, Volume: 71

    Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Diabetic Neuropathies; Hematinics; Humans; Hydrogen Cyanide; Hydroxocobalamin; Neuritis; Vitamin B 12; Vitamin B Complex

1963
[HYDROXYCOBALAMIN AS A "FLUSHING" DOSE IN THE SCHILLING TEST].
    Minerva nucleare, 1963, Volume: 7

    Topics: Anemia; Anemia, Pernicious; Diagnosis; Gastroenterology; Humans; Hydroxocobalamin; Kidney Diseases; Schilling Test; Vitamin B 12 Deficiency

1963
[THERAPEUTIC APPLICATIONS OF HYDROXOCOBALAMINE, THIAMINE AND PYRIDOXINE IN A CONJOINED FORM].
    La Semana medica, 1963, Dec-26, Volume: 123

    Topics: Anemia; Child; Depression; Depressive Disorder; Feeding and Eating Disorders; Geriatrics; Humans; Hydroxocobalamin; Liver Cirrhosis; Pyridoxine; Thiamine

1963