Page last updated: 2024-10-18

hydroquinone and Skin Aging

hydroquinone has been researched along with Skin Aging in 18 studies

Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.

Research Excerpts

ExcerptRelevanceReference
"This investigator-blinded, randomized trial was conducted to compare a new hydroquinone (HQ)-free hyperpigmentation regimen against a leading HQ-based hyperpigmentation regimen for the treatment of facial hyperpigmentation and photoaging."9.17Comparative study of hydroquinone-free and hydroquinone-based hyperpigmentation regimens in treating facial hyperpigmentation and photoaging. ( Fabi, SG; Goldman, MP, 2013)
"This double-blind, randomized, split-face study compares the effects of a new OTC non-hydroquinone lightening product (JM) to an available 4% hydroquinone lightening solution (OB) on the appearance of hyperpigmentation, texture, and ne lines and wrinkles."5.22Split-Face Comparison of an Advanced Non-Hydroquinone Lightening Solution to 4% Hydroquinone. ( Mohr, S; Saxena, S; Schlessinger, J, 2016)
"This investigator-blinded, randomized trial was conducted to compare a new hydroquinone (HQ)-free hyperpigmentation regimen against a leading HQ-based hyperpigmentation regimen for the treatment of facial hyperpigmentation and photoaging."5.17Comparative study of hydroquinone-free and hydroquinone-based hyperpigmentation regimens in treating facial hyperpigmentation and photoaging. ( Fabi, SG; Goldman, MP, 2013)
"Compared with standard skin care, the HQ system plus tretinoin resulted in significantly milder fine lines/wrinkles and hyperpigmentation at Days 30, 90, and 120 (p ≤ ."5.15Further enhancement of facial appearance with a hydroquinone skin care system plus tretinoin in patients previously treated with botulinum toxin Type A. ( Kenkel, J; Schlessinger, J; Werschler, P, 2011)
"Patients with facial mottled hyperpigmentation of at least moderate severity and an overall integrated assessment of photodamage score of at least moderate applied tazarotene 0."5.12Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study. ( Draelos, Z; Horwitz, S; Lowe, N; Menter, A; Tanghetti, E, 2006)
"Combination therapy of hydroquinone and retinol may improve photoaging-associated hyperpigmentation."5.11Novel approach to the treatment of hyperpigmented photodamaged skin: 4% hydroquinone/0.3% retinol versus tretinoin 0.05% emollient cream. ( Draelos, ZD, 2005)
"Hydroquinone 4% cream with 2% glycolic acid is safe and effective in improving photodamage on the neck and upper chest when used alone or in combination with salicylic acid peels."2.69Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest. ( Gladstone, HB; Jeffers, M; Moy, RL; Nguyen, SL; Ottomeyer, T; Williams, R; Wortzman, M, 2000)
"Hydroquinone exhibited a lower penetration through senescent skin than young skin."1.40The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: nude mouse as an animal model. ( Aljuffali, IA; Chen, WY; Fang, JY; Hung, CF; Shih, HC, 2014)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's6 (33.33)29.6817
2010's10 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, D1
Lin, SB1
Cheng, B1
Fabi, SG1
Goldman, MP2
Hung, CF1
Chen, WY1
Aljuffali, IA1
Shih, HC1
Fang, JY1
Rendon, M1
Dryer, L1
Rendon, MI1
Barkovic, S1
Schlessinger, J2
Saxena, S1
Mohr, S1
Woodhall, KE1
Gold, MH1
Biron, J1
Leyden, JJ1
Parr, L1
Puizina-Ivić, N1
Mirić, L1
Carija, A1
Karlica, D1
Marasović, D1
Kenkel, J1
Werschler, P1
Bruce, S3
Watson, J1
Draelos, ZD2
Lowe, N1
Horwitz, S1
Tanghetti, E1
Draelos, Z1
Menter, A1
Apfelberg, DB1
Gladstone, HB1
Nguyen, SL1
Williams, R1
Ottomeyer, T1
Wortzman, M1
Jeffers, M1
Moy, RL1

Reviews

4 reviews available for hydroquinone and Skin Aging

ArticleYear
Complications and posttreatment care following invasive laser skin resurfacing: A review.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2018, Volume: 20, Issue:3

    Topics: Antibiotic Prophylaxis; Bandages; Collagen; Cosmetic Techniques; Elastin; Epidermal Growth Factor; H

2018
Modern approach to topical treatment of aging skin.
    Collegium antropologicum, 2010, Volume: 34, Issue:3

    Topics: Administration, Topical; Antioxidants; Chemexfoliation; Humans; Hydroquinones; Retinoids; Skin Aging

2010
Cosmeceuticals for the attenuation of extrinsic and intrinsic dermal aging.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:2 Suppl

    Topics: Administration, Topical; Antioxidants; Benzoquinones; Cosmetics; Dermatologic Agents; Drug Combinati

2008
Topical agents used in association with cosmetic surgery.
    Seminars in cutaneous medicine and surgery, 1999, Volume: 18, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Ascorbic Acid; Carotenoids; Chemexfoliation; Dicar

1999

Trials

9 trials available for hydroquinone and Skin Aging

ArticleYear
Comparative study of hydroquinone-free and hydroquinone-based hyperpigmentation regimens in treating facial hyperpigmentation and photoaging.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:3

    Topics: Administration, Cutaneous; Adult; Dermatologic Agents; Female; Follow-Up Studies; Humans; Hydroquino

2013
Split-Face Comparison of an Advanced Non-Hydroquinone Lightening Solution to 4% Hydroquinone.
    Journal of drugs in dermatology : JDD, 2016, Dec-01, Volume: 15, Issue:12

    Topics: Double-Blind Method; Drug Compounding; Face; Follow-Up Studies; Humans; Hydroquinones; Hyperpigmenta

2016
Benefits of using a hydroquinone/tretinoin skin care system in patients undergoing intense pulsed light therapy for photorejuvenation: a placebo-controlled study.
    Journal of drugs in dermatology : JDD, 2009, Volume: 8, Issue:9

    Topics: Administration, Cutaneous; Adult; Female; Follow-Up Studies; Humans; Hydroquinones; Hyperpigmentatio

2009
Treating photodamage of the décolletage area with a novel copper zinc malonate complex plus hydroquinone and tretinoin.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:3

    Topics: Adult; Copper; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Hydroquinones; Malona

2010
Further enhancement of facial appearance with a hydroquinone skin care system plus tretinoin in patients previously treated with botulinum toxin Type A.
    Aesthetic surgery journal, 2011, Volume: 31, Issue:5

    Topics: Administration, Cutaneous; Botulinum Toxins, Type A; Face; Female; Follow-Up Studies; Humans; Hydroq

2011
Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:12

    Topics: Adult; Ascorbic Acid; Dermatologic Agents; Drug Combinations; Female; Follow-Up Studies; Humans; Hyd

2011
Novel approach to the treatment of hyperpigmented photodamaged skin: 4% hydroquinone/0.3% retinol versus tretinoin 0.05% emollient cream.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2005, Volume: 31, Issue:7 Pt 2

    Topics: Administration, Topical; Adult; Dermatologic Agents; Double-Blind Method; Drug Combinations; Emollie

2005
Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2006, Volume: 8, Issue:3

    Topics: Administration, Topical; Chi-Square Distribution; Dermatologic Agents; Double-Blind Method; Female;

2006
Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2000, Volume: 26, Issue:4

    Topics: Chemexfoliation; Female; Glycolates; Humans; Hydroquinones; Hyperpigmentation; Keratolytic Agents; M

2000

Other Studies

5 other studies available for hydroquinone and Skin Aging

ArticleYear
The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: nude mouse as an animal model.
    International journal of pharmaceutics, 2014, Aug-25, Volume: 471, Issue:1-2

    Topics: Animals; Cadherins; Cyclooxygenase 2; Dose-Response Relationship, Radiation; Female; Hair Follicle;

2014
Investigator-Blinded, Single-Center Study to Evaluate the Efficacy and Tolerability of a 4% Hydroquinone Skin Care System Plus 0.02% Tretinoin Cream in Mild-to-Moderate Melasma and Photodamage.
    Journal of drugs in dermatology : JDD, 2016, Volume: 15, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Drug Compounding; Drug Therapy, Combination; Female; Humans;

2016
Clinical Evaluation of a 4% Hydroquinone + 1% Retinol Treatment Regimen for Improving Melasma and Photodamage in Fitzpatrick Skin Types III-VI.
    Journal of drugs in dermatology : JDD, 2016, Nov-01, Volume: 15, Issue:11

    Topics: Administration, Cutaneous; Adult; Aged; Drug Compounding; Drug Therapy, Combination; Female; Humans;

2016
Complementary effects of topical antiaging treatments in conjunction with aesthetic procedures.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:2 Suppl

    Topics: Administration, Topical; Antioxidants; Botulinum Toxins, Type A; Cosmetic Techniques; Drug Combinati

2008
Ultrapulse carbon dioxide laser with CPG scanner for full-face resurfacing for rhytids, photoaging, and acne scars.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:7

    Topics: Acne Vulgaris; Acyclovir; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antiviral Agents

1997