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hydroquinone and Leukemia, Myeloid, Acute

hydroquinone has been researched along with Leukemia, Myeloid, Acute in 10 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome and acute myelogenous leukemia."3.70The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 2000)
"Chronic exposure of humans to benzene (BZ), a Class I carcinogen, causes acute myelogenous leukemia, possibly via its bone marrow metabolite, hydroquinone (HQ)."3.69Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor. ( Hazel, BA; Kalf, GF, 1996)
"Chronic exposure of humans to benzene causes acute myelogenous leukemia (AML)."3.69Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone. ( Hazel, BA; Kalf, GF; Niculescu, R; O'Connor, A, 1996)
"Hydroquinone is a phenolic metabolite of benzene, a known human carcinogen."2.48Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature. ( Brautbar, N; Regev, L; Wu, M; Zlotolow, R, 2012)
"Benzene exposure is a risk factor of acute myeloid leukemia (AML), during such carcinogenesis long non-coding RNAs (lncRNAs) are important epigenetic regulators."1.56Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene. ( Ling, X; Liu, L; Pan, Z; Tan, Q; Wu, M; Xie, D; Xie, P; Yuan, Q; Zhang, H; Zheng, D, 2020)
"Benzene is a known environmental pollutant with demonstrated leukemogenic activity."1.38How benzene and its metabolites affect human marrow derived mesenchymal stem cells. ( Amirizadeh, N; Hosseinkhani, S; Nazem, S; Sadeghizadeh, M; Zolghadr, F, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Zhang, H1
Yuan, Q1
Pan, Z1
Ling, X1
Tan, Q1
Wu, M2
Zheng, D1
Xie, P1
Xie, D1
Liu, L1
Camus, M1
Wierzbicka-Hainaut, E1
Dammak, A1
Fromont, G1
Guillet, G1
Ji, Z1
Zhang, L1
Peng, V1
Ren, X1
McHale, CM1
Smith, MT1
Regev, L1
Zlotolow, R1
Brautbar, N1
Zolghadr, F1
Sadeghizadeh, M1
Amirizadeh, N1
Hosseinkhani, S1
Nazem, S1
Zheng, JH1
Pyatt, DW1
Gross, SA1
Le, AT1
Kerzic, PJ1
Irons, RD2
Hazel, BA2
Kalf, GF3
Hutt, AM1
O'Connor, A1
Niculescu, R1
Stillman, WS1
Varella-Garcia, M1

Reviews

1 review available for hydroquinone and Leukemia, Myeloid, Acute

ArticleYear
Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature.
    Toxicology and industrial health, 2012, Volume: 28, Issue:1

    Topics: Adult; Animals; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pai

2012

Other Studies

9 other studies available for hydroquinone and Leukemia, Myeloid, Acute

ArticleYear
Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene.
    Toxicology letters, 2020, Apr-01, Volume: 322

    Topics: Benzene; Case-Control Studies; Cell Line, Transformed; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltra

2020
Hydroquinone is both effective on pigmentation and lichenoid papules of chronic lichenoid graft-versus-host disease.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2010, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Chronic Disease; Combined Modality Therapy; Fema

2010
A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide.
    Leukemia, 2010, Volume: 24, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cells, Cultured; Chromosomes,

2010
How benzene and its metabolites affect human marrow derived mesenchymal stem cells.
    Toxicology letters, 2012, Oct-17, Volume: 214, Issue:2

    Topics: Apoptosis; Benzene; Benzoquinones; Calcium-Binding Proteins; Caspases; Cell Survival; Chemokine CXCL

2012
Hydroquinone modulates the GM-CSF signaling pathway in TF-1 cells.
    Leukemia, 2004, Volume: 18, Issue:7

    Topics: Antigens, CD34; Bone Marrow Cells; Carcinogens; Cell Division; Cell Line, Tumor; Granulocyte-Macroph

2004
Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor.
    Receptors & signal transduction, 1996, Volume: 6, Issue:1

    Topics: Animals; Benzene; Cell Differentiation; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocyt

1996
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Benzene; Benzoquinones; Carcinogens; DNA Damage; DNA, Kinetoplast; Enzyme Inhibitors; Human

1996
Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzene; Carcinogens; Cell Differentiation; Granulocytes; HL-6

1996
The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells.
    Experimental hematology, 2000, Volume: 28, Issue:2

    Topics: Benzene; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Hematop

2000