hydroquinone has been researched along with Leukemia, Myeloid, Acute in 10 studies
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome and acute myelogenous leukemia." | 3.70 | The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 2000) |
| "Chronic exposure of humans to benzene (BZ), a Class I carcinogen, causes acute myelogenous leukemia, possibly via its bone marrow metabolite, hydroquinone (HQ)." | 3.69 | Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor. ( Hazel, BA; Kalf, GF, 1996) |
| "Chronic exposure of humans to benzene causes acute myelogenous leukemia (AML)." | 3.69 | Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone. ( Hazel, BA; Kalf, GF; Niculescu, R; O'Connor, A, 1996) |
| "Hydroquinone is a phenolic metabolite of benzene, a known human carcinogen." | 2.48 | Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature. ( Brautbar, N; Regev, L; Wu, M; Zlotolow, R, 2012) |
| "Benzene exposure is a risk factor of acute myeloid leukemia (AML), during such carcinogenesis long non-coding RNAs (lncRNAs) are important epigenetic regulators." | 1.56 | Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene. ( Ling, X; Liu, L; Pan, Z; Tan, Q; Wu, M; Xie, D; Xie, P; Yuan, Q; Zhang, H; Zheng, D, 2020) |
| "Benzene is a known environmental pollutant with demonstrated leukemogenic activity." | 1.38 | How benzene and its metabolites affect human marrow derived mesenchymal stem cells. ( Amirizadeh, N; Hosseinkhani, S; Nazem, S; Sadeghizadeh, M; Zolghadr, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Yuan, Q | 1 |
| Pan, Z | 1 |
| Ling, X | 1 |
| Tan, Q | 1 |
| Wu, M | 2 |
| Zheng, D | 1 |
| Xie, P | 1 |
| Xie, D | 1 |
| Liu, L | 1 |
| Camus, M | 1 |
| Wierzbicka-Hainaut, E | 1 |
| Dammak, A | 1 |
| Fromont, G | 1 |
| Guillet, G | 1 |
| Ji, Z | 1 |
| Zhang, L | 1 |
| Peng, V | 1 |
| Ren, X | 1 |
| McHale, CM | 1 |
| Smith, MT | 1 |
| Regev, L | 1 |
| Zlotolow, R | 1 |
| Brautbar, N | 1 |
| Zolghadr, F | 1 |
| Sadeghizadeh, M | 1 |
| Amirizadeh, N | 1 |
| Hosseinkhani, S | 1 |
| Nazem, S | 1 |
| Zheng, JH | 1 |
| Pyatt, DW | 1 |
| Gross, SA | 1 |
| Le, AT | 1 |
| Kerzic, PJ | 1 |
| Irons, RD | 2 |
| Hazel, BA | 2 |
| Kalf, GF | 3 |
| Hutt, AM | 1 |
| O'Connor, A | 1 |
| Niculescu, R | 1 |
| Stillman, WS | 1 |
| Varella-Garcia, M | 1 |
1 review available for hydroquinone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Hydroquinone, a benzene metabolite, and leukemia: a case report and review of the literature.
Topics: Adult; Animals; Benzene; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pai | 2012 |
9 other studies available for hydroquinone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene.
Topics: Benzene; Case-Control Studies; Cell Line, Transformed; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltra | 2020 |
Hydroquinone is both effective on pigmentation and lichenoid papules of chronic lichenoid graft-versus-host disease.
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Chronic Disease; Combined Modality Therapy; Fema | 2010 |
A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cells, Cultured; Chromosomes, | 2010 |
How benzene and its metabolites affect human marrow derived mesenchymal stem cells.
Topics: Apoptosis; Benzene; Benzoquinones; Calcium-Binding Proteins; Caspases; Cell Survival; Chemokine CXCL | 2012 |
Hydroquinone modulates the GM-CSF signaling pathway in TF-1 cells.
Topics: Antigens, CD34; Bone Marrow Cells; Carcinogens; Cell Division; Cell Line, Tumor; Granulocyte-Macroph | 2004 |
Induction of granulocytic differentiation in myeloblasts by hydroquinone, a metabolite of benzene, involves the leukotriene D4 receptor.
Topics: Animals; Benzene; Cell Differentiation; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocyt | 1996 |
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
Topics: Animals; Benzene; Benzoquinones; Carcinogens; DNA Damage; DNA, Kinetoplast; Enzyme Inhibitors; Human | 1996 |
Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzene; Carcinogens; Cell Differentiation; Granulocytes; HL-6 | 1996 |
The benzene metabolite, hydroquinone, selectively induces 5q31- and -7 in human CD34+CD19- bone marrow cells.
Topics: Benzene; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Hematop | 2000 |