hydroquinone has been researched along with Kidney Neoplasms in 11 studies
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recently, the US Food and Drug Administration proposed a ban on over-the-counter hydroquinone mainly on the basis of high absorption, reports of exogenous ochronosis in humans, and murine hepatic adenomas, renal adenomas, and leukemia with large doses over extended time periods." | 4.84 | The safety of hydroquinone: a dermatologist's response to the 2006 Federal Register. ( Levitt, J, 2007) |
| "Hydroquinone (HQ) produced renal adenomas in male F344 rats, and these tumors appeared to arise from areas of spontaneous progressive nephropathy; the nephropathy itself has been found to be enhanced by HQ." | 4.79 | Analysis of studies related to tumorigenicity induced by hydroquinone. ( English, JC; Verna, L; Whysner, J; Williams, GM, 1995) |
| "Hydroquinone (HQ) is a potential human carcinogen to which many people are exposed." | 1.31 | Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone. ( Everitt, JI; Kleymenova, E; Lau, SS; Monks, TJ; Walker, CL, 2001) |
| " No differences in survival were observed between dosed and control groups of rats or mice." | 1.28 | Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice. ( Bucher, J; Eustis, SL; Haseman, JK; Huff, JE; Kari, FW, 1992) |
| "Hydroquinone (HQ) was administered to F344 rats and B6C3F1 mice of both sexes at a level of 0." | 1.28 | Induction of renal cell tumors in rats and mice, and enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment. ( Asakawa, E; Hirose, M; Ito, N; Shibata, MA; Shirai, T; Tanaka, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levitt, J | 1 |
| Okazaki, S | 1 |
| Hoshiya, T | 1 |
| Takahashi, S | 2 |
| Futakuchi, M | 1 |
| Saito, K | 1 |
| Hirose, M | 4 |
| Whysner, J | 1 |
| Verna, L | 1 |
| English, JC | 1 |
| Williams, GM | 1 |
| Shirai, T | 2 |
| Ogawa, K | 1 |
| Ito, N | 3 |
| Lau, SS | 4 |
| Peters, MM | 2 |
| Kleiner, HE | 1 |
| Canales, PL | 1 |
| Monks, TJ | 4 |
| Jones, TW | 1 |
| Everitt, JI | 2 |
| Kleymenova, E | 1 |
| Walker, CL | 2 |
| Yoon, HS | 1 |
| Patel, SK | 1 |
| Kari, FW | 1 |
| Bucher, J | 1 |
| Eustis, SL | 1 |
| Haseman, JK | 1 |
| Huff, JE | 1 |
| Shibata, MA | 1 |
| Tanaka, H | 1 |
| Asakawa, E | 1 |
| Hasegawa, R | 1 |
| Furukawa, F | 1 |
| Toyoda, K | 1 |
| Takahashi, M | 1 |
| Hayashi, Y | 1 |
3 reviews available for hydroquinone and Kidney Neoplasms
| Article | Year |
|---|---|
The safety of hydroquinone: a dermatologist's response to the 2006 Federal Register.
Topics: Absorption; Adenoma; Animals; Carcinogenicity Tests; Drug Approval; Fertility; Humans; Hydroquinones | 2007 |
Analysis of studies related to tumorigenicity induced by hydroquinone.
Topics: Adenoma; Animals; Carcinogenicity Tests; Female; Humans; Hydroquinones; Kidney Neoplasms; Leukemia; | 1995 |
Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Division; Cell Transformation, Neoplastic; Glutath | 2001 |
8 other studies available for hydroquinone and Kidney Neoplasms
| Article | Year |
|---|---|
Modification of hepato- and renal carcinogenesis by catechol and its isomers in rats pretreated with N-ethyl-N-hydroxyethylnitrosamine.
Topics: Adenoma; Administration, Oral; Alpha-Globulins; Animals; Body Weight; Carcinoma, Renal Cell; Catecho | 1993 |
Organ-specific modification of carcinogenesis by antioxidants in rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzodioxoles; Butylated Hydroxyanisole; Caffeic Aci | 1993 |
Linking the metabolism of hydroquinone to its nephrotoxicity and nephrocarcinogenicity.
Topics: Animals; Carcinogens; Cattle; Cell Death; DNA; DNA Damage; Hydroquinones; Hyperplasia; Kidney; Kidne | 1996 |
Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone.
Topics: Animals; Carcinogens; Cell Division; Cell Survival; gamma-Glutamyltransferase; Glutathione; Hydroqui | 1997 |
Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.
Topics: Animals; Biotransformation; Carcinogens; Cell Division; Genes, Tumor Suppressor; Germ-Line Mutation; | 2001 |
Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice.
Topics: Administration, Oral; Animals; Corn Oil; Dose-Response Relationship, Drug; Epithelium; Female; Hydro | 1992 |
Induction of renal cell tumors in rats and mice, and enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Diet; Female; Hydroquinones; Hyperplasi | 1991 |
Inhibitory effects of antioxidants on N-bis(2-hydroxypropyl)nitrosamine-induced lung carcinogenesis in rats.
Topics: Adenoma; Animals; Antioxidants; Ascorbic Acid; Body Weight; Butylated Hydroxyanisole; Butylated Hydr | 1990 |