Page last updated: 2024-10-18

hydroquinone and Erythema

hydroquinone has been researched along with Erythema in 12 studies

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
" Hydroquinone (HQ) is the gold standard and remains the only prescription product available in the United States for the treatment of generalized facial hyperpigmentation."9.17Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. ( Banga, A; Jain, P; Makino, ET; Mehta, RC; Sigler, ML; Sonti, S, 2013)
"In this prospective pilot study, we evaluated the efficacy and safety for a novel combination therapy based on low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's melanosis."7.85A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis. ( Choi, SC; Jung, JY; Kwon, HH; Kwon, IH; Ohn, J; Park, GH; Park, HY; Suh, DH, 2017)
"To evaluate the erythema and pigmentation of melasma lesions and the surrounding areas in patients receiving triple combination (TC: hydroquinone, tretinoin, and fluocinolone acetonide) regimens."5.19Objective assessment of erythema and pigmentation of melasma lesions and surrounding areas in long-term management regimens with triple combination. ( Fernandes, JD; Hexsel, D; Siega, C; Soirefmann, M, 2014)
" Hydroquinone (HQ) is the gold standard and remains the only prescription product available in the United States for the treatment of generalized facial hyperpigmentation."5.17Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. ( Banga, A; Jain, P; Makino, ET; Mehta, RC; Sigler, ML; Sonti, S, 2013)
"To evaluate the efficiency and adverse effects of 10% all-trans retinol (ROL) gel for improvement of skin hyperpigmentation."5.10Clinical trial of bleaching treatment with 10% all-trans retinol gel. ( Aiba, E; Aoyama, T; Harii, K; Iga, T; Matsumoto, D; Mitoma, Y; Momosawa, A; Sato, K; Yoshimura, K, 2003)
"In this prospective pilot study, we evaluated the efficacy and safety for a novel combination therapy based on low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's melanosis."3.85A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis. ( Choi, SC; Jung, JY; Kwon, HH; Kwon, IH; Ohn, J; Park, GH; Park, HY; Suh, DH, 2017)
"Tranexamic acid (TA) is a relatively new brightening agent that interferes with keratinocyte-melanocyte interactions."2.87Comparing the efficacy of topical hydroquinone 2% versus intradermal tranexamic acid microinjections in treating melasma: a split-face controlled trial. ( Darayesh, M; Heiran, A; Saki, N, 2018)
" HQ was introduced into these formulations to provide a safe and effective alternative to mercury and other less effective ingredients."1.30Lack of nephrotoxicity and renal cell proliferation following subchronic dermal application of a hydroquinone cream. ( David, RM; English, JC; Moyer, C; O'Donoghue, JL; Totman, LC, 1998)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chalermchai, T1
Rummaneethorn, P1
Saki, N1
Darayesh, M1
Heiran, A1
Makino, ET1
Mehta, RC1
Banga, A1
Jain, P1
Sigler, ML1
Sonti, S1
Hexsel, D2
Hexsel, C1
Porto, MD1
Siega, C2
Soirefmann, M1
Fernandes, JD1
Imhof, L1
Dummer, R1
Dreier, J1
Kolm, I1
Barysch, MJ1
Kwon, HH1
Ohn, J1
Suh, DH1
Park, HY1
Choi, SC1
Jung, JY1
Kwon, IH1
Park, GH1
Yoshimura, K1
Momosawa, A1
Aiba, E1
Sato, K1
Matsumoto, D1
Mitoma, Y1
Harii, K1
Aoyama, T1
Iga, T1
Apfelberg, DB1
David, RM1
English, JC1
Totman, LC1
Moyer, C1
O'Donoghue, JL1
Chess, C1
Goldman, MP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
OneDoc Picopulse™ for the Treatment of Melasma Among Malaysian Women[NCT04834167]32 participants (Actual)Interventional2021-05-01Completed
Comparing Tranexamic Acid Microinjection Alone Versus Its Combination With Fractional Carbon Dioxide Laser in Melasma Treatment[NCT03899233]Phase 425 participants (Anticipated)Interventional2019-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroquinone and Erythema

ArticleYear
The use of hydroquinone with facial laser resurfacing.
    Journal of cutaneous laser therapy, 2000, Volume: 2, Issue:2

    Topics: Erythema; Humans; Hydroquinones; Hyperpigmentation; Laser Therapy; Lasers; Radiation-Protective Agen

2000

Trials

7 trials available for hydroquinone and Erythema

ArticleYear
Effects of a fractional picosecond 1,064 nm laser for the treatment of dermal and mixed type melasma.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2018, Volume: 20, Issue:3

    Topics: Adult; Erythema; Female; Humans; Hydroquinones; Lasers, Solid-State; Low-Level Light Therapy; Melano

2018
Comparing the efficacy of topical hydroquinone 2% versus intradermal tranexamic acid microinjections in treating melasma: a split-face controlled trial.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:4

    Topics: Administration, Topical; Adult; Erythema; Face; Female; Humans; Hydroquinones; Melanins; Melanosis;

2018
Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:3

    Topics: Administration, Cutaneous; Adult; Dermatologic Agents; Dose-Response Relationship, Radiation; Double

2013
Triple combination as adjuvant to cryotherapy in the treatment of solar lentigines: investigator-blinded, randomized clinical trial.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Chemotherapy, Adjuvant; Cryotherapy;

2015
Objective assessment of erythema and pigmentation of melasma lesions and surrounding areas in long-term management regimens with triple combination.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antioxidants; Drug Therapy, Combination; Erythema; Fluo

2014
A Prospective Trial Comparing Q-Switched Ruby Laser and a Triple Combination Skin-Lightening Cream in the Treatment of Solar Lentigines.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2016, Volume: 42, Issue:7

    Topics: Aged; Dexamethasone; Drug Combinations; Erythema; Female; Hand Dermatoses; Humans; Hydroquinones; La

2016
Clinical trial of bleaching treatment with 10% all-trans retinol gel.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2003, Volume: 29, Issue:2

    Topics: Adult; Aged; Ascorbic Acid; Dermatitis, Irritant; Drug Therapy, Combination; Erythema; Female; Gels;

2003

Other Studies

4 other studies available for hydroquinone and Erythema

ArticleYear
A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis.
    The Journal of dermatological treatment, 2017, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Combined Modality Therapy; Erythema; Facial

2017
Ultrapulse carbon dioxide laser with CPG scanner for full-face resurfacing for rhytids, photoaging, and acne scars.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:7

    Topics: Acne Vulgaris; Acyclovir; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antiviral Agents

1997
Lack of nephrotoxicity and renal cell proliferation following subchronic dermal application of a hydroquinone cream.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:7

    Topics: Administration, Cutaneous; Animals; Cell Division; Erythema; Female; gamma-Glutamyltransferase; Hydr

1998
Nothing like a little science now and then.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:5

    Topics: Erythema; Glycolates; Humans; Hydroquinones; Keratolytic Agents; Laser Therapy; Lasers; Pigmentation

1999