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hydroquinone and Aneuploid

hydroquinone has been researched along with Aneuploid in 24 studies

Research Excerpts

ExcerptRelevanceReference
"Previously, we have shown that phenyl hydroquinone, a hepatic metabolite of the Ames test-negative carcinogen o-phenylphenol, efficiently induced aneuploidy in Saccharomyces cerevisiae by arresting the cell cycle at the G2/M transition as a result of the activation of the Hog1 (p38 MAPK homolog)-Swe1 (Wee1 homolog) pathway."7.76Hydroquinone, a benzene metabolite, induces Hog1-dependent stress response signaling and causes aneuploidy in Saccharomyces cerevisiae. ( Shiga, T; Suzuki, H; Yamamoto, A; Yamamoto, H; Yamamoto, K, 2010)
" In this context, the effects of colchicine (COL) and hydroquinone (HQ) on cell-cycle progression, aneuploidy, polyploidy, micronucleus and sister chromatid exchange induction in mouse bone marrow cells after bromodeoxyuridine incorporation are reported."7.68Origin of aneuploidy in relation to disturbances of cell-cycle progression. II: Cytogenetic analysis of various parameters in mouse bone marrow cells after colchicine or hydroquinone treatment. ( Bassani, B; Leopardi, P; Pacchierotti, F; Zijno, A, 1991)
"The synopsis of the in vivo test results in the first collaborative CEC Aneuploidy Project with 10 selected chemicals, colchicine (COL), econazole (EZ), chloral hydrate (CH), hydroquinone (HQ), diazepam (DZ), thiabendazole (TB), cadmium chloride (CD), thimerosal (TM), pyrimethamine (PY) and vinblastine (VBL), allowed several conclusions."4.78Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. ( Adler, ID, 1993)
"Recently, we have shown that phenyl hydroquinone, a hepatic metabolite of the Ames test-negative carcinogen o-phenylphenol, efficiently induced aneuploidy in Saccharomyces cerevisiae."3.74Phenyl hydroquinone, an Ames test-negative carcinogen, induces Hog1-dependent stress response signaling. ( Enomoto, T; Nunoshiba, T; Umezu, K; Yamamoto, A; Yamamoto, K, 2008)
"Micronuclei (MN) obtained from mouse bone marrow cells, in vivo exposed to 3 typical clastogens (procarbazine, azathioprine, ethyl methanesulfonate) and 3 typical aneuploidogens (vinblastine, tubulazole, colchicine), were examined for C-band, area and DNA content."3.68Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow. ( Deleener, A; Kirsch-Volders, M; Van Hummelen, P; Vanparys, P, 1992)
", colchicine (COL), econazole(EZ) and hydroquinone (HQ) have been assayed by means of C-Mitotic (CM) effects, micronucleus (MN) and chromosomal aberration (CA) test for their effects of aneuploid induction in mouse bone marrow cells COL induced poly/aneuploid in mouse bone marrow cells."3.68[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells]. ( Adler, ID; Kliesch, U; Miller, B; Wang, X, 1991)
" In this context, the effects of colchicine (COL) and hydroquinone (HQ) on cell-cycle progression, aneuploidy, polyploidy, micronucleus and sister chromatid exchange induction in mouse bone marrow cells after bromodeoxyuridine incorporation are reported."3.68Origin of aneuploidy in relation to disturbances of cell-cycle progression. II: Cytogenetic analysis of various parameters in mouse bone marrow cells after colchicine or hydroquinone treatment. ( Bassani, B; Leopardi, P; Pacchierotti, F; Zijno, A, 1991)
"We tested the 10 known or suspected spindle poisons (colchicine, econazole nitrate, chloral hydrate, hydroquinone, diazepam, thiabendazole, cadmium chloride, thimerosal, pyrimethamine and vinblastine) of the coordinated EEC programme for induction of aneuploidy with the in vitro porcine brain tubulin assembly assay."3.68Effects of 10 known or suspected spindle poisons in the in vitro porcine brain tubulin assembly assay. ( Albertini, S; Brunner, M; Würgler, FE, 1991)
"Pyrimethamine did not inhibit the assembly of microtubules, but produced aberrant forms."1.29Effects of potential aneuploidy inducing agents on microtubule assembly in vitro. ( Hartley-Asp, B; Wallin, M, 1993)
"The test chemicals included in the EC Aneuploidy Project were evaluated for their ability to induce aneuploidy or aneuploidy related endpoints in assays using in vitro tubulin polymerisation, fungi and wheat."1.29An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens. ( Parry, JM, 1993)
"Cadmium chloride was negative in the chromosome enumeration assay and hydroquinone yielded inconclusive results."1.29A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens. ( Parry, EM; Parry, JM; Warr, TJ, 1993)
"Mitomycin-C (MMC) was used as a positive control for the induction of micronuclei."1.29The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. ( Lynch, AM; Parry, JM, 1993)
"An analysis of chromosomal aberrations was carried out in bone marrow cells of mice with the first five chemicals: colchicine (COL), econazole (EZ), chloralhydrate (CH), hydroquinone (HQ) and diazepam (DIAZ)."1.28Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells. ( Adler, ID; Xu, W, 1990)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's19 (79.17)18.2507
2000's2 (8.33)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ji, Z1
McHale, CM1
Bersonda, J1
Tung, J1
Smith, MT3
Zhang, L3
Yamamoto, A2
Nunoshiba, T1
Umezu, K1
Enomoto, T1
Yamamoto, K2
Shiga, T1
Suzuki, H1
Yamamoto, H1
Ferguson, LR1
Morcombe, P1
Triggs, CN1
Natarajan, AT2
Leopardi, P2
Zijno, A2
Bassani, B2
Pacchierotti, F2
Adler, ID4
Wallin, M1
Hartley-Asp, B1
Parry, JM4
Warr, TJ1
Parry, EM1
Sors, A1
Duivenvoorden, WC1
Meijers, M1
Zwanenburg, TS1
Lynch, AM1
Voutsinas, G1
Zarani, FE1
Kappas, A2
Wang, Y2
Shang, N1
Jeng, M1
Guo, W1
Duramad, P1
Hubbard, AE1
Hofstadler, G1
Holland, NT1
Van Hummelen, P2
Deleener, A1
Vanparys, P1
Kirsch-Volders, M2
Wang, X1
Miller, B1
Kliesch, U2
Brunner, M1
Albertini, S1
Würgler, FE1
Crebelli, R1
Conti, G1
Conti, L1
Carere, A1
Xu, W1

Reviews

2 reviews available for hydroquinone and Aneuploid

ArticleYear
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromos

1993
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Aspergillus; Cadmium; Cadmium Chloride; Cell Cycle; Cells, Cultured; Chloral Hy

1993

Other Studies

22 other studies available for hydroquinone and Aneuploid

ArticleYear
Induction of centrosome amplification by formaldehyde, but not hydroquinone, in human lymphoblastoid TK6 cells.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:6

    Topics: Aneuploidy; Cell Line; Centrosome; Chromosome Aberrations; Dose-Response Relationship, Drug; Etoposi

2015
Phenyl hydroquinone, an Ames test-negative carcinogen, induces Hog1-dependent stress response signaling.
    The FEBS journal, 2008, Volume: 275, Issue:22

    Topics: Aneuploidy; Biphenyl Compounds; Carcinogens; Cell Cycle; Cell Cycle Proteins; G2 Phase; Hydroquinone

2008
Hydroquinone, a benzene metabolite, induces Hog1-dependent stress response signaling and causes aneuploidy in Saccharomyces cerevisiae.
    Journal of radiation research, 2010, Volume: 51, Issue:4

    Topics: Aneuploidy; Benzene; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 2; Genes, Fungal; Hydroquino

2010
The size of cytokinesis-blocked micronuclei in human peripheral blood lymphocytes as a measure of aneuploidy induction by Set A compounds in the EEC trial.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Cell Division; Cells, Cultured; Chloral Hydrate; Colchicine; Cytoplasm; Diazepam; Dose-R

1993
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral H

1993
In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Bone Marrow; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine;

1993
Effects of potential aneuploidy inducing agents on microtubule assembly in vitro.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Brain; Cadmium; Cadmium Chloride; Cattle; Chloral Hydrate; Chlorides; Colchicin

1993
An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Co

1993
A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat

1993
Induction of mitotic aneuploidy using Chinese hamster primary embryonic cells. Test results of 10 chemicals.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Colchic

1993
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
    Mutation research, 1993, Volume: 287, Issue:1

    Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrat

1993
The effect of environmental aneuploidy-inducing agents on the microtubule architecture of mitotic meristematic root cells in Hordeum vulgare.
    Cell biology international, 1997, Volume: 21, Issue:7

    Topics: Aneuploidy; Anti-Infective Agents; Cadmium Chloride; Hordeum; Hydroquinones; Meristem; Microtubules;

1997
Benzene metabolites induce the loss and long arm deletion of chromosomes 5 and 7 in human lymphocytes.
    Leukemia research, 1998, Volume: 22, Issue:2

    Topics: Aneuploidy; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Humans; Hyd

1998
Hydroquinone, a benzene metabolite, increases the level of aneusomy of chromosomes 7 and 8 in human CD34-positive blood progenitor cells.
    Carcinogenesis, 2000, Volume: 21, Issue:8

    Topics: Aneuploidy; Antigens, CD34; Cells, Cultured; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8;

2000
Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow.
    Mutation research, 1992, Volume: 271, Issue:1

    Topics: Aneuploidy; Animals; Azacitidine; Azathioprine; Bone Marrow; Chromosome Banding; Colchicine; Dioxola

1992
[A study of aneuploid induction by three mitotic arrestants in mouse bone marrow cells].
    Yi chuan xue bao = Acta genetica Sinica, 1991, Volume: 18, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Chromosome Aberrations; Colchicine; Econazole; Female; Hydroquinon

1991
Origin of aneuploidy in relation to disturbances of cell-cycle progression. II: Cytogenetic analysis of various parameters in mouse bone marrow cells after colchicine or hydroquinone treatment.
    Mutagenesis, 1991, Volume: 6, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cell Division; Chromosome Aberratio

1991
Mouse micronucleus tests with known and suspect spindle poisons: results from two laboratories.
    Mutagenesis, 1991, Volume: 6, Issue:1

    Topics: Aneuploidy; Animals; Bone Marrow Cells; Chromosome Aberrations; Colchicine; Erythrocytes; Europe; Fe

1991
Effects of 10 known or suspected spindle poisons in the in vitro porcine brain tubulin assembly assay.
    Mutagenesis, 1991, Volume: 6, Issue:1

    Topics: Aneuploidy; Animals; Brain; Chloral Hydrate; Colchicine; Diazepam; Hydroquinones; Microtubules; Muta

1991
In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans.
    Mutagenesis, 1991, Volume: 6, Issue:2

    Topics: Aneuploidy; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chromosomes, Fungal; C

1991
Clastogenic effects of known and suspect spindle poisons studied by chromosome analysis in mouse bone marrow cells.
    Mutagenesis, 1990, Volume: 5, Issue:4

    Topics: Aneuploidy; Animals; Bone Marrow; Bone Marrow Cells; Chloral Hydrate; Chromosome Aberrations; Colchi

1990
On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations.
    Progress in clinical and biological research, 1989, Volume: 318

    Topics: Aneuploidy; Animals; Aspergillus nidulans; Benomyl; Chloral Hydrate; Colchicine; Econazole; Hydroqui

1989