hydrogen sulfide has been researched along with Ventricular Dysfunction, Left in 8 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure." | 8.31 | Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. ( Beck, KF; Elrod, JW; Goodchild, TT; Katsouda, A; LaPenna, KB; Lefer, DJ; Li, Z; Papapetropoulos, A; Pfeilschifter, J; Sharp, TE; Xia, H; Xian, M; Xu, S, 2023) |
| " The goal of the present study was to determine the therapeutic potential of a stable, long-acting H2S donor, diallyl trisulfide, in a model of pressure-overload heart failure and to assess the effects of chronic H2S therapy on myocardial vascular density and angiogenesis." | 7.79 | Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis. ( Bhushan, S; Bir, SC; Calvert, JW; Kevil, CG; Kondo, K; Lefer, DJ; Murohara, T; Polhemus, D, 2013) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 5.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| "Hydrogen sulfide is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure." | 4.31 | Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. ( Beck, KF; Elrod, JW; Goodchild, TT; Katsouda, A; LaPenna, KB; Lefer, DJ; Li, Z; Papapetropoulos, A; Pfeilschifter, J; Sharp, TE; Xia, H; Xian, M; Xu, S, 2023) |
| "The present study was designed to investigate the protective effects of hydrogen sulfide (H2S) against cigarette smoking-induced left ventricular dysfunction in rats." | 3.80 | Hydrogen sulfide improves left ventricular function in smoking rats via regulation of apoptosis and autophagy. ( An, G; Chen, J; Zhou, X, 2014) |
| " The goal of the present study was to determine the therapeutic potential of a stable, long-acting H2S donor, diallyl trisulfide, in a model of pressure-overload heart failure and to assess the effects of chronic H2S therapy on myocardial vascular density and angiogenesis." | 3.79 | Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis. ( Bhushan, S; Bir, SC; Calvert, JW; Kevil, CG; Kondo, K; Lefer, DJ; Murohara, T; Polhemus, D, 2013) |
| "Hydrogen sulfide (H2S) is an important endogenous modulator of diverse physiological and pathophysiological processes." | 1.42 | GYY4137 attenuates remodeling, preserves cardiac function and modulates the natriuretic peptide response to ischemia. ( Liew, OW; Lilyanna, S; Martinez, EC; Moore, PK; Peh, MT; Richards, AM; Wang, P, 2015) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 1.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Z | 2 |
| Xia, H | 2 |
| Sharp, TE | 2 |
| LaPenna, KB | 2 |
| Elrod, JW | 3 |
| Casin, KM | 1 |
| Liu, K | 1 |
| Calvert, JW | 3 |
| Chau, VQ | 1 |
| Salloum, FN | 1 |
| Xu, S | 2 |
| Xian, M | 2 |
| Nagahara, N | 1 |
| Goodchild, TT | 2 |
| Lefer, DJ | 4 |
| Katsouda, A | 1 |
| Pfeilschifter, J | 1 |
| Beck, KF | 1 |
| Papapetropoulos, A | 1 |
| Haouzi, P | 1 |
| Tubbs, N | 1 |
| Cheung, J | 1 |
| Judenherc-Haouzi, A | 1 |
| Polhemus, D | 1 |
| Kondo, K | 1 |
| Bhushan, S | 1 |
| Bir, SC | 1 |
| Kevil, CG | 1 |
| Murohara, T | 1 |
| Zhou, X | 1 |
| An, G | 1 |
| Chen, J | 1 |
| Lilyanna, S | 1 |
| Peh, MT | 1 |
| Liew, OW | 1 |
| Wang, P | 1 |
| Moore, PK | 1 |
| Richards, AM | 1 |
| Martinez, EC | 1 |
| Ge, N | 1 |
| Liu, C | 1 |
| Li, G | 1 |
| Xie, L | 1 |
| Zhang, Q | 1 |
| Li, L | 1 |
| Hao, N | 1 |
| Zhang, J | 1 |
| Elston, M | 1 |
| Nicholson, CK | 1 |
| Gundewar, S | 1 |
| Jha, S | 1 |
| Ramachandran, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-Term Endogenous Hydrogen Sulfide Upregulation For Vein Graft Disease[NCT05457881] | 226 participants (Anticipated) | Interventional | 2024-03-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for hydrogen sulfide and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Mitochondrial H
Topics: Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Heart Failure; Humans; Hydrogen Sulfid | 2022 |
Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure.
Topics: Animals; Endothelial Cells; Endothelium, Vascular; Fibrosis; Heart Failure; Hydrogen Sulfide; Mice; | 2023 |
Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action.
Topics: Animals; Antidotes; Cytochromes c; Echocardiography; Female; Gas Poisoning; Hemoglobins; Hydrogen Su | 2019 |
Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis.
Topics: Allyl Compounds; Angiostatins; Animals; Disease Models, Animal; Fibrosis; Heart Failure; Hydrogen Su | 2013 |
Hydrogen sulfide improves left ventricular function in smoking rats via regulation of apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Gasotransmitters; Hydrogen Sulfide; JNK Mitogen-Activated Protein Kin | 2014 |
GYY4137 attenuates remodeling, preserves cardiac function and modulates the natriuretic peptide response to ischemia.
Topics: Animals; Atrial Natriuretic Factor; Cardiotonic Agents; Humans; Hydrogen Sulfide; Ischemia; Morpholi | 2015 |
Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3β/β-catenin signaling pathway.
Topics: Animals; Apoptosis; beta Catenin; Biomarkers; Blood Pressure; Disease Models, Animal; Glycogen Synth | 2016 |
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.
Topics: Animals; Body Weight; Cardiomegaly; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymolog | 2010 |