Page last updated: 2024-10-17

hydrogen sulfide and Shock

hydrogen sulfide has been researched along with Shock in 9 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
"There is ample evidence that nitric oxide, carbon monoxide, and H2S may exert cytoprotective effects in shock states due to their vasomotor, antioxidant, and anti-inflammatory properties as well as their potential to induce a hibernation-like metabolic state called 'suspended animation' resulting from inhibition of cytochrome-c-oxidase."8.85Applying gases for microcirculatory and cellular oxygenation in sepsis: effects of nitric oxide, carbon monoxide, and hydrogen sulfide. ( Baumgart, K; Radermacher, P; Wagner, F, 2009)
"There is ample evidence that nitric oxide, carbon monoxide, and H2S may exert cytoprotective effects in shock states due to their vasomotor, antioxidant, and anti-inflammatory properties as well as their potential to induce a hibernation-like metabolic state called 'suspended animation' resulting from inhibition of cytochrome-c-oxidase."4.85Applying gases for microcirculatory and cellular oxygenation in sepsis: effects of nitric oxide, carbon monoxide, and hydrogen sulfide. ( Baumgart, K; Radermacher, P; Wagner, F, 2009)
" sepsis), while in other disease states H2 S levels and H2 S bioavailability are reduced and its therapeutic replacement is warranted (e."2.50Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects. ( Bos, EM; Bouillaud, F; Calzia, E; Coletta, C; Hellmich, MR; Módis, K; Papapetropoulos, A; Radermacher, P; Szabo, C; van Goor, H, 2014)
" Finally, in addition to the question of dosing and timing (for example, bolus administration versus continuous intravenous infusion), the preferred route of H2S administration remains to be settled--that is, inhaling gaseous H2S versus intra-venous administration of injectable H2S preparations or H2S donors."2.45Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care. ( Asfar, P; Calzia, E; Radermacher, P; Szabó, C; Wagner, F, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Módis, K1
Bos, EM1
Calzia, E4
van Goor, H1
Coletta, C1
Papapetropoulos, A1
Hellmich, MR1
Radermacher, P6
Bouillaud, F1
Szabo, C4
McCook, O1
Volani, C1
Asfar, P2
Ignatius, A1
Kemmler, J1
Möller, P1
Whiteman, M1
Wood, ME1
Wang, R1
Georgieff, M2
Wachter, U2
Sonobe, T1
Haouzi, P1
Baumgart, K2
Wagner, F2
Collin, M1
Thiemermann, C1
Simon, F1
Giudici, R1
Duy, CN1
Schelzig, H1
Oter, S1
Gröger, M1
Vogt, J1
Speit, G1
Kiyota, K1
Suzuki, T1
Adachi, T1
Nonaka, A1
Nishigawa, Y1
Hamabe, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091]Phase 220 participants (Anticipated)Interventional2019-08-05Recruiting
Hydrogen Sulfide as Prognostic Factor[NCT01088490]50 participants (Actual)Observational2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for hydrogen sulfide and Shock

ArticleYear
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects.
    British journal of pharmacology, 2014, Volume: 171, Issue:8

    Topics: Animals; Diabetes Complications; Energy Metabolism; Gasotransmitters; Hibernation; Humans; Hydrogen

2014
H2S during circulatory shock: some unresolved questions.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Animals; Clinical Chemistry Tests; Humans; Hydrogen Sulfide; Mice; Rats; Shock; Sulfides; Swine

2014
Applying gases for microcirculatory and cellular oxygenation in sepsis: effects of nitric oxide, carbon monoxide, and hydrogen sulfide.
    Current opinion in anaesthesiology, 2009, Volume: 22, Issue:2

    Topics: Animals; Carbon Monoxide; Hydrogen Sulfide; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Ty

2009
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care.
    Critical care (London, England), 2009, Volume: 13, Issue:3

    Topics: Animals; Hibernation; Humans; Hydrogen Sulfide; Inflammation; Reperfusion Injury; Shock; Signal Tran

2009

Other Studies

5 other studies available for hydrogen sulfide and Shock

ArticleYear
Sulfide Intoxication-Induced Circulatory Failure is Mediated by a Depression in Cardiac Contractility.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:1

    Topics: Air Pollutants; Anesthesia; Animals; Arterial Pressure; Blood Gas Analysis; Cardiac Output; Heart Ve

2016
Cardioprotection by hydrogen sulfide: suspended animation, inflammation, and apoptosis.
    Shock (Augusta, Ga.), 2009, Volume: 31, Issue:2

    Topics: Animals; Apoptosis; Gene Deletion; Humans; Hydrogen Sulfide; Hypoxia; Inflammation; Models, Biologic

2009
Hydrogen sulfide and sulfite: novel mediators in the pathophysiology of shock and inflammation.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:6

    Topics: Animals; Biomarkers; Humans; Hydrogen Sulfide; Inflammation; Shock; Sulfites

2005
Hemodynamic and metabolic effects of hydrogen sulfide during porcine ischemia/reperfusion injury.
    Shock (Augusta, Ga.), 2008, Volume: 30, Issue:4

    Topics: Animals; Aorta; Carbon Dioxide; Female; Glucose; Hemodynamics; Hydrogen Sulfide; Lactates; Male; Mit

2008
[Fatal calcium polysulfide overdose presenting corrosive chemical injury of esophagus and sulf-hemoglobinemia].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2002, Volume: 15, Issue:2

    Topics: Aged; Burns, Chemical; Calcium Compounds; Drug Overdose; Esophageal Stenosis; Esophagitis; Esophagus

2002