hydrogen sulfide has been researched along with Pulmonary Fibrosis in 8 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study investigated the role of the endogenous cystathionine gamma-lyase (CSE) / hydrogen sulfide pathway in the pathogenesis of pulmonary fibrosis." | 7.75 | Hydrogen sulfide attenuates the pathogenesis of pulmonary fibrosis induced by bleomycin in rats. ( Fang, L; Geng, B; Li, H; Liu, X; Qi, Y; Tang, C, 2009) |
| "To explore the change of endogenous hydrogen sulfide and the effect of exogenously applied H(2)S on Bleomycin-induced pulmonary fibrosis in rats." | 7.73 | [Effect of hydrogen sulfide on Bleomycin-induced pulmonary fibrosis in rats]. ( Geng, B; Li, H; Liu, XM; Pan, CS; Qi, YF; Tang, CS; Wu, SY, 2006) |
| " Treatment with either NaHS or BM-MSC leads to an inhibitory effect on pulmonary fibrosis as evidenced by improvement of histopathological studies, pulmonary function tests, reduction of inflammatory and fibrotic markers like Hydroxyproline, TNF α, TGF-β and caspase -3 together with downregulation miR-21 and increase lncRNA-GAS5 expression." | 5.51 | Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5. ( Abdelmonsif, DA; Ali, RG; Badae, NM; Nassar, SZ, 2022) |
| "Hydrogen sulfide (H2S) displays vasodilative, anti-oxidative, anti-inflammatory and cytoprotective activities." | 5.40 | Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance. ( Cao, H; Chu, L; Huang, X; Zhai, Y; Zhang, J; Zhang, X; Zhou, X, 2014) |
| "We previously reported that the endogenous cystathionine gamma-lyase (CSE)/hydrogen sulfide (H(2)S) pathway is implicated in the pathogenesis of bleomycin-induced pulmonary fibrosis in rats, but the exact cellular mechanisms are not well characterized." | 3.76 | Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells. ( Fang, LP; Lin, Q; Liu, XM; Tang, CS, 2010) |
| "The present study investigated the role of the endogenous cystathionine gamma-lyase (CSE) / hydrogen sulfide pathway in the pathogenesis of pulmonary fibrosis." | 3.75 | Hydrogen sulfide attenuates the pathogenesis of pulmonary fibrosis induced by bleomycin in rats. ( Fang, L; Geng, B; Li, H; Liu, X; Qi, Y; Tang, C, 2009) |
| "To explore the change of endogenous hydrogen sulfide and the effect of exogenously applied H(2)S on Bleomycin-induced pulmonary fibrosis in rats." | 3.73 | [Effect of hydrogen sulfide on Bleomycin-induced pulmonary fibrosis in rats]. ( Geng, B; Li, H; Liu, XM; Pan, CS; Qi, YF; Tang, CS; Wu, SY, 2006) |
| "Hydrogen sulfide (H2S) displays vasodilative, anti-oxidative, anti-inflammatory and cytoprotective activities." | 1.40 | Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance. ( Cao, H; Chu, L; Huang, X; Zhai, Y; Zhang, J; Zhang, X; Zhou, X, 2014) |
| "Inflammation was assessed by measuring serum levels of inflammatory cytokines, including high-sensitivity C-reactive protein, tumour necrosis factor-α, interleukin (IL)-1β and IL-6." | 1.40 | Inhibitory effects of hydrogen sulphide on pulmonary fibrosis in smoking rats via attenuation of oxidative stress and inflammation. ( An, G; Chen, J; Zhou, X, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Nassar, SZ | 1 |
| Abdelmonsif, DA | 1 |
| Ali, RG | 1 |
| Badae, NM | 1 |
| Cao, H | 1 |
| Zhou, X | 2 |
| Zhang, J | 1 |
| Huang, X | 1 |
| Zhai, Y | 1 |
| Zhang, X | 1 |
| Chu, L | 1 |
| An, G | 1 |
| Chen, J | 1 |
| Fang, L | 1 |
| Li, H | 2 |
| Tang, C | 1 |
| Geng, B | 2 |
| Qi, Y | 1 |
| Liu, X | 1 |
| Fang, LP | 1 |
| Lin, Q | 1 |
| Tang, CS | 2 |
| Liu, XM | 2 |
| Pan, CS | 1 |
| Qi, YF | 1 |
| Wu, SY | 1 |
| Duong, TX | 1 |
| Suruda, AJ | 1 |
| Maier, LA | 1 |
| Parra, O | 1 |
| Monsó, E | 1 |
| Gallego, M | 1 |
| Morera, J | 1 |
1 trial available for hydrogen sulfide and Pulmonary Fibrosis
| Article | Year |
|---|---|
Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5.
Topics: Animals; Bleomycin; Bone Marrow; Caspases; Hydrogen Sulfide; Hydroxyproline; Male; Mesenchymal Stem | 2022 |
7 other studies available for hydrogen sulfide and Pulmonary Fibrosis
| Article | Year |
|---|---|
Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Diff | 2014 |
Inhibitory effects of hydrogen sulphide on pulmonary fibrosis in smoking rats via attenuation of oxidative stress and inflammation.
Topics: Air Pollutants; Animals; Blotting, Western; Cells, Cultured; Electrophoretic Mobility Shift Assay; E | 2014 |
Hydrogen sulfide attenuates the pathogenesis of pulmonary fibrosis induced by bleomycin in rats.
Topics: Animals; Bleomycin; Hydrogen Sulfide; Hydroxyl Radical; Male; Oxidation-Reduction; Pulmonary Alveoli | 2009 |
Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells.
Topics: Benzodioxoles; Cadherins; Cell Line, Tumor; Cell Transdifferentiation; Cystathionine gamma-Lyase; Dr | 2010 |
[Effect of hydrogen sulfide on Bleomycin-induced pulmonary fibrosis in rats].
Topics: Animals; Bleomycin; Cystathionine gamma-Lyase; Hydrogen Sulfide; Lung; Male; Pulmonary Artery; Pulmo | 2006 |
Interstitial fibrosis following hydrogen sulfide exposure.
Topics: Air Pollutants; Humans; Hydrogen Sulfide; Male; Middle Aged; Occupational Exposure; Pulmonary Fibros | 2001 |
Inhalation of hydrogen sulphide: a case of subacute manifestations and long term sequelae.
Topics: Accidents, Occupational; Adult; Bronchitis; Hemorrhage; Humans; Hydrogen Sulfide; Inhalation; Male; | 1991 |