Page last updated: 2024-10-17

hydrogen sulfide and Parkinson Disease

hydrogen sulfide has been researched along with Parkinson Disease in 24 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Studies have shown that hydrogen sulfide (H2S) exerts a neuroprotective effect and may have a therapeutic value for treating neurodegenerative diseases including Parkinson's disease."3.88Involvement of adenosine triphosphate-sensitive potassium channels in the neuroprotective activity of hydrogen sulfide in the 6-hydroxydopamine-induced animal model of Parkinson's disease. ( Babayan-Tazehkand, A; Haghdoost-Yazdi, H; Rastgoo, N; Sarbazi-Golezari, A; Sarookhani, MR, 2018)
"Hydrogen sulfide (H2S) has a neuroprotective effect during the neural injury of Parkinson's disease."1.43Involvement of microRNA-135a-5p in the Protective Effects of Hydrogen Sulfide Against Parkinson's Disease. ( Li, J; Liao, S; Lin, Y; Liu, Y; Quan, H; Yang, Q, 2016)
"Hydrogen sulfide (H2S) is a multifunctional signaling molecule that exerts neuroprotective effects in oxidative stress."1.39A ratiometric two-photon fluorescent probe reveals reduction in mitochondrial H2S production in Parkinson's disease gene knockout astrocytes. ( Bae, SK; Cho, BR; Choi, DJ; Heo, CH; Joe, EH; Kim, HM; Sen, D, 2013)
"Hydrogen sulfide (H(2)S) has been shown to protect neurons."1.37Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease. ( Ichinose, F; Kakinohana, M; Kaneki, M; Kida, K; Marutani, E; Tokuda, K; Yamada, M, 2011)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's16 (66.67)24.3611
2020's8 (33.33)2.80

Authors

AuthorsStudies
Tian, Q1
Tang, HL1
Tang, YY1
Zhang, P1
Kang, X1
Zou, W1
Tang, XQ2
Murros, KE1
Nagashima, F2
Miyazaki, Y2
Kanemaru, E2
Ezaka, M2
Hara, H2
Sugiura, K2
Boerboom, SL2
Ostrom, KF2
Jiang, W2
Bloch, DB2
Ichinose, F4
Marutani, E3
Nie, S1
Jing, Z1
Wang, J2
Deng, Y1
Zhang, Y1
Ye, Z1
Ge, Y1
Wu, K1
Wang, X2
Gong, L1
Zhai, X1
Wang, K1
Qiu, X1
Zhang, H1
Tang, Z1
Jiang, H1
Shen, Q1
Huang, Z1
Zhang, D1
Chen, X1
Du, F1
Zhou, Z1
Fu, C1
Li, L1
Yang, N1
Yu, C1
Liu, L1
Wang, H1
Shen, W1
Wang, P1
Xie, Z1
Zhou, H1
Hu, Y1
Fu, M1
Zhu, Q1
Shefa, U1
Yeo, SG1
Kim, MS1
Song, IO1
Jung, J1
Jeong, NY1
Huh, Y1
Cakmak, YO2
Cao, X1
Cao, L1
Ding, L1
Bian, JS2
Yuan, YQ1
Wang, YL1
Yuan, BS1
Yuan, X1
Hou, XO1
Liu, CF2
Hu, LF1
Barbe, AG1
Deutscher, DHC1
Derman, SHM1
Hellmich, M1
Noack, MJ1
Sarookhani, MR1
Haghdoost-Yazdi, H2
Sarbazi-Golezari, A1
Babayan-Tazehkand, A2
Rastgoo, N2
Sarukhani, M1
Sarbazi Golezari, A1
Dargahi, T1
Bae, SK1
Heo, CH1
Choi, DJ1
Sen, D1
Joe, EH1
Cho, BR1
Kim, HM1
Paul, BD1
Snyder, SH1
Kida, K2
Liu, Y1
Liao, S1
Quan, H1
Lin, Y1
Li, J1
Yang, Q1
Fan, LL1
Li, YJ2
Shen, XT1
Zhuan, YY1
He, JQ1
Xu, JH1
Hu, B1
Lee, M1
Tazzari, V1
Giustarini, D1
Rossi, R1
Sparatore, A1
Del Soldato, P1
McGeer, E1
McGeer, PL1
Yamada, M1
Tokuda, K1
Kakinohana, M1
Kaneki, M1
Du, CC1
Xu, JM1

Reviews

6 reviews available for hydrogen sulfide and Parkinson Disease

ArticleYear
Hydrogen Sulfide Produced by Gut Bacteria May Induce Parkinson's Disease.
    Cells, 2022, 03-12, Volume: 11, Issue:6

    Topics: alpha-Synuclein; Bacteria; Humans; Hydrogen Sulfide; Iron; Parkinson Disease

2022
Role of Gasotransmitters in Oxidative Stresses, Neuroinflammation, and Neuronal Repair.
    BioMed research international, 2017, Volume: 2017

    Topics: Alzheimer Disease; Carbon Monoxide; Cardiovascular System; Gasotransmitters; Humans; Hydrogen Sulfid

2017
Rotorua, hydrogen sulphide and Parkinson's disease-A possible beneficial link?
    The New Zealand medical journal, 2017, 05-12, Volume: 130, Issue:1455

    Topics: Air Pollutants; Animals; Humans; Hydrogen Sulfide; Models, Animal; New Zealand; Parkinson Disease

2017
A New Hope for a Devastating Disease: Hydrogen Sulfide in Parkinson's Disease.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Humans; Hydrogen Sulfide; Neurons; Parkinson Dise

2018
Modes of physiologic H2S signaling in the brain and peripheral tissues.
    Antioxidants & redox signaling, 2015, Feb-10, Volume: 22, Issue:5

    Topics: Animals; Brain; Cardiovascular System; Gasotransmitters; Gastrointestinal Tract; Homeostasis; Humans

2015
Hydrogen Sulfide and Neuroinflammation.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Apoptosis; Humans; Hydrogen Sulfide; Inflammation; Parkinson Disease

2015

Other Studies

18 other studies available for hydrogen sulfide and Parkinson Disease

ArticleYear
Hydrogen Sulfide Attenuates the Cognitive Dysfunction in Parkinson's Disease Rats via Promoting Hippocampal Microglia M2 Polarization by Enhancement of Hippocampal Warburg Effect.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Cognitive Dysfunction; Hippocampus; Humans; Hydrogen Sulfide; Male; Microglia; Parkinson Di

2022
Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease.
    Redox biology, 2023, Volume: 59

    Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Mice; Parkinson Disease; Quinones; Sulfides

2023
Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease.
    Redox biology, 2023, Volume: 59

    Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Mice; Parkinson Disease; Quinones; Sulfides

2023
Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease.
    Redox biology, 2023, Volume: 59

    Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Mice; Parkinson Disease; Quinones; Sulfides

2023
Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease.
    Redox biology, 2023, Volume: 59

    Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Mice; Parkinson Disease; Quinones; Sulfides

2023
The link between increased Desulfovibrio and disease severity in Parkinson's disease.
    Applied microbiology and biotechnology, 2023, Volume: 107, Issue:9

    Topics: Desulfovibrio; Humans; Hydrogen Sulfide; Neurodegenerative Diseases; Parkinson Disease; Patient Acui

2023
Screening of H
    Biosensors & bioelectronics, 2023, Oct-01, Volume: 237

    Topics: Biosensing Techniques; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Mitochondria; Neurode

2023
A novel coumarin-fluorescein-based fluorescent probe for ultrafast and visual detection of H
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2024, Feb-05, Volume: 306

    Topics: Animals; Coumarins; Fluorescein; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Parkinson D

2024
Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP
    Molecular and cellular biochemistry, 2020, Volume: 472, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Caspase 3; Cell Survival; Gasotransmitters; Herbicides; Huma

2020
A bifunctional probe reveals increased viscosity and hydrogen sulfide in zebra fish model of Parkinson's disease.
    Talanta, 2021, Nov-01, Volume: 234

    Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Parkinson Disease; Viscosity; Zebra

2021
Impaired CBS-H
    Brain, behavior, and immunity, 2018, Volume: 67

    Topics: Animals; Astrocytes; Cell Line, Tumor; Cells, Cultured; Corpus Striatum; Cystathionine beta-Synthase

2018
Subjective and objective halitosis among patients with Parkinson's disease.
    Gerodontology, 2017, Volume: 34, Issue:4

    Topics: Aged; Case-Control Studies; Female; Halitosis; Humans; Hydrogen Sulfide; Male; Parkinson Disease; Sa

2017
Involvement of adenosine triphosphate-sensitive potassium channels in the neuroprotective activity of hydrogen sulfide in the 6-hydroxydopamine-induced animal model of Parkinson's disease.
    Behavioural pharmacology, 2018, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dop

2018
Evaluation of the antiparkinsonism and neuroprotective effects of hydrogen sulfide in acute 6-hydroxydopamine-induced animal model of Parkinson's disease: behavioral, histological and biochemical studies.
    Neurological research, 2018, Volume: 40, Issue:7

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopam

2018
A ratiometric two-photon fluorescent probe reveals reduction in mitochondrial H2S production in Parkinson's disease gene knockout astrocytes.
    Journal of the American Chemical Society, 2013, Jul-03, Volume: 135, Issue:26

    Topics: Astrocytes; Fluorescent Dyes; Humans; Hydrogen Sulfide; Intracellular Signaling Peptides and Protein

2013
Coffee consumption, smoking, and Parkinson's disease? The beneficial role of hydrogen sulfide.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:3

    Topics: Coffee; Humans; Hydrogen Sulfide; Parkinson Disease; Risk Factors; Smoking

2016
Involvement of microRNA-135a-5p in the Protective Effects of Hydrogen Sulfide Against Parkinson's Disease.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3' Untranslated Regions; Animals; Apomorphine; Astrocy

2016
Inhibition of hydrogen sulfide generation contributes to 1-methy-4-phenylpyridinium ion-induced neurotoxicity.
    Neurotoxicity research, 2011, Volume: 19, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Survival; Humans; Hydrogen Sulfide; Neurons; Parkinson Di

2011
Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease.
    The Journal of biological chemistry, 2010, Jun-04, Volume: 285, Issue:23

    Topics: Animals; Cell Line; Cell Line, Tumor; Humans; Hydrogen Sulfide; Interleukin-6; Levodopa; Mitochondri

2010
Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease.
    Antioxidants & redox signaling, 2011, Jul-15, Volume: 15, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Inhalation; Animals; Apoptosis; Base S

2011
[Hydrogen sulfide: a promising target for the treatment of Parkinson's disease].
    Sheng li ke xue jin zhan [Progress in physiology], 2012, Volume: 43, Issue:4

    Topics: Animals; Humans; Hydrogen Sulfide; Parkinson Disease

2012