hydrogen sulfide has been researched along with Pain in 30 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide (H(2) S), generated by enzymes such as cystathionine-γ-lyase (CSE) from L-cysteine, facilitates pain signals by activating the Ca(v) 3." | 7.78 | Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. ( Hayashi, Y; Kawabata, A; Kubo, L; Matsunami, M; Miki, T; Nishikawa, H; Nishiura, K; Okawa, Y; Ozaki, T; Sekiguchi, F; Tsujiuchi, T, 2012) |
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator with the ability to modulate tissue inflammation and pain." | 7.74 | Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis. ( Andruski, B; Ignacy, T; McCafferty, DM; McDougall, JJ; Millen, B, 2008) |
| "Hydrogen sulfide (H(2)S) plays an important role in cardiovascular, central nervous, and gastrointestinal systems." | 6.46 | Hydrogen sulfide and substance P in inflammation. ( Bhatia, M, 2010) |
| "Hydrogen sulfide (H2S) is a gasotransmitter endogenously generated from the metabolism of L-cysteine by action of two main enzymes called cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE)." | 5.39 | Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats. ( Araiza-Saldaña, CI; Barragán-Iglesias, P; Flores-Murrieta, FJ; Godínez-Chaparro, B; Navarrete, A; Roa-Coria, JE; Rocha-González, HI; Torres-López, JE; Velasco-Xolalpa, ME, 2013) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Hydrogen sulfide (H2S), an endogenous gaseotransmitter/modulator, is becoming appreciated that it may be involved in a wide variety of processes including inflammation and nociception." | 3.80 | Upregulation of cystathionine-β-synthetase expression contributes to inflammatory pain in rat temporomandibular joint. ( Hu, S; Ju, Z; Meng, X; Miao, X; Wu, G; Xu, GY; Zhang, HH, 2014) |
| "2 are involved in the H(2)S-induced mucosal cytoprotection against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats." | 3.78 | Hydrogen sulfide-induced colonic mucosal cytoprotection involves T-type calcium channel-dependent neuronal excitation in rats. ( Kawabata, A; Kirishi, S; Matsunami, M; Okui, T, 2012) |
| "Hydrogen sulfide (H(2) S), generated by enzymes such as cystathionine-γ-lyase (CSE) from L-cysteine, facilitates pain signals by activating the Ca(v) 3." | 3.78 | Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. ( Hayashi, Y; Kawabata, A; Kubo, L; Matsunami, M; Miki, T; Nishikawa, H; Nishiura, K; Okawa, Y; Ozaki, T; Sekiguchi, F; Tsujiuchi, T, 2012) |
| "Given recent evidence that hydrogen sulfide (H(2)S), a gasotransmitter, promotes somatic pain through redox modulation of T-type Ca(2+) channels, the roles of colonic luminal H(2)S in visceral nociceptive processing in mice were examined." | 3.75 | Luminal hydrogen sulfide plays a pronociceptive role in mouse colon. ( Fukushima, O; Kawabata, A; Matsunami, M; Mitani, K; Nagasawa, K; Okubo, K; Takemura, M; Tarui, T; Yoshida, S, 2009) |
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator with the ability to modulate tissue inflammation and pain." | 3.74 | Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis. ( Andruski, B; Ignacy, T; McCafferty, DM; McDougall, JJ; Millen, B, 2008) |
| "The present study investigated the hypothesis that hydrogen sulfide (H2S) is pro-nociceptive in the formalin model of persistent inflammatory pain in the adult rat." | 3.74 | A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain. ( Cheng, Y; Khanna, S; Lee, AT; Li, L; Moore, PK; Shah, JJ, 2008) |
| "Physiopathological mechanisms and treatment of pain remain a significant challenge." | 2.47 | Hydrogen sulphide and pain. ( Distrutti, E, 2011) |
| "Hydrogen sulfide (H(2)S) plays an important role in cardiovascular, central nervous, and gastrointestinal systems." | 2.46 | Hydrogen sulfide and substance P in inflammation. ( Bhatia, M, 2010) |
| "1." | 2.46 | Interaction of hydrogen sulfide with ion channels. ( Tang, G; Wang, R; Wu, L, 2010) |
| "Hydrogen sulfide also plays an important role in promoting resolution of inflammation, and restoration of normal tissue function." | 1.42 | Anti-inflammatory and cytoprotective properties of hydrogen sulfide. ( Gemici, B; Wallace, JL, 2015) |
| "Hydrogen sulfide (H2S) is a gasotransmitter endogenously generated from the metabolism of L-cysteine by action of two main enzymes called cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE)." | 1.39 | Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats. ( Araiza-Saldaña, CI; Barragán-Iglesias, P; Flores-Murrieta, FJ; Godínez-Chaparro, B; Navarrete, A; Roa-Coria, JE; Rocha-González, HI; Torres-López, JE; Velasco-Xolalpa, ME, 2013) |
| "Hydrogen sulfide (H(2)S) is an endogenous gas involved in several biological functions, including modulation of nociception." | 1.35 | Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. ( Cunha, FQ; Cunha, TM; Dal-Secco, D; Ferreira, SH; Guerrero, AT; Lotufo, CM; Neto, AF; Souza, GR; Verri, WA; Vieira, SM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 20 (66.67) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glanville, JRW | 1 |
| Jalali, P | 1 |
| Flint, JD | 1 |
| Patel, AA | 1 |
| Maini, AA | 1 |
| Wallace, JL | 2 |
| Hosin, AA | 1 |
| Gilroy, DW | 1 |
| Dichiara, M | 1 |
| Artacho-Cordón, A | 1 |
| Turnaturi, R | 1 |
| Santos-Caballero, M | 1 |
| González-Cano, R | 1 |
| Pasquinucci, L | 1 |
| Barbaraci, C | 1 |
| Rodríguez-Gómez, I | 1 |
| Gómez-Guzmán, M | 1 |
| Marrazzo, A | 1 |
| Cobos, EJ | 1 |
| Amata, E | 1 |
| Garattini, EG | 1 |
| Santos, BM | 1 |
| Ferrari, DP | 1 |
| Capel, CP | 1 |
| Francescato, HDC | 1 |
| Coimbra, TM | 1 |
| Leite-Panissi, CRA | 1 |
| Branco, LGS | 1 |
| Nascimento, GC | 1 |
| Velasco-Xolalpa, ME | 1 |
| Barragán-Iglesias, P | 1 |
| Roa-Coria, JE | 1 |
| Godínez-Chaparro, B | 1 |
| Flores-Murrieta, FJ | 1 |
| Torres-López, JE | 1 |
| Araiza-Saldaña, CI | 1 |
| Navarrete, A | 1 |
| Rocha-González, HI | 1 |
| Takahashi, K | 1 |
| Ohta, T | 1 |
| Miao, X | 1 |
| Meng, X | 1 |
| Wu, G | 1 |
| Ju, Z | 1 |
| Zhang, HH | 1 |
| Hu, S | 1 |
| Xu, GY | 1 |
| Tsubota, M | 1 |
| Kawabata, A | 7 |
| Gemici, B | 1 |
| Dief, AE | 1 |
| Mostafa, DK | 1 |
| Sharara, GM | 1 |
| Zeitoun, TH | 1 |
| Terada, Y | 1 |
| Fukami, K | 2 |
| Sekiguchi, F | 3 |
| Cunha, TM | 2 |
| Dal-Secco, D | 1 |
| Verri, WA | 2 |
| Guerrero, AT | 1 |
| Souza, GR | 1 |
| Vieira, SM | 1 |
| Lotufo, CM | 1 |
| Neto, AF | 1 |
| Ferreira, SH | 1 |
| Cunha, FQ | 1 |
| Andruski, B | 1 |
| McCafferty, DM | 1 |
| Ignacy, T | 1 |
| Millen, B | 1 |
| McDougall, JJ | 1 |
| Matsunami, M | 3 |
| Tarui, T | 1 |
| Mitani, K | 1 |
| Nagasawa, K | 1 |
| Fukushima, O | 1 |
| Okubo, K | 1 |
| Yoshida, S | 1 |
| Takemura, M | 1 |
| Bhatia, M | 1 |
| Blachier, F | 1 |
| Davila, AM | 1 |
| Mimoun, S | 1 |
| Benetti, PH | 1 |
| Atanasiu, C | 1 |
| Andriamihaja, M | 1 |
| Benamouzig, R | 1 |
| Bouillaud, F | 1 |
| Tomé, D | 1 |
| Distrutti, E | 3 |
| Cipriani, S | 1 |
| Renga, B | 1 |
| Mencarelli, A | 1 |
| Migliorati, M | 1 |
| Cianetti, S | 1 |
| Fiorucci, S | 4 |
| Tang, G | 1 |
| Wu, L | 1 |
| Wang, R | 1 |
| Santucci, L | 1 |
| Kirishi, S | 1 |
| Okui, T | 1 |
| Lötsch, J | 1 |
| Walter, C | 1 |
| Felden, L | 1 |
| Nöth, U | 1 |
| Deichmann, R | 1 |
| Oertel, BG | 1 |
| Miki, T | 1 |
| Nishiura, K | 1 |
| Hayashi, Y | 1 |
| Okawa, Y | 1 |
| Nishikawa, H | 1 |
| Kubo, L | 1 |
| Ozaki, T | 1 |
| Tsujiuchi, T | 1 |
| Kobal, G | 1 |
| Lee, AT | 1 |
| Shah, JJ | 1 |
| Li, L | 1 |
| Cheng, Y | 1 |
| Moore, PK | 1 |
| Khanna, S | 1 |
| Chmielewski, H | 1 |
| Szafranko, J | 1 |
| Krysińska, L | 1 |
9 reviews available for hydrogen sulfide and Pain
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
[Role of hydrogen sulfide, a gasotransmitter, in colonic pain and inflammation].
Topics: Animals; Colitis; Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Pain; Signal Transductio | 2014 |
H2S and Pain: A Novel Aspect for Processing of Somatic, Visceral and Neuropathic Pain Signals.
Topics: Animals; Calcium Channels; Calcium Channels, T-Type; Humans; Hydrogen Sulfide; Mice; Nerve Tissue Pr | 2015 |
Hydrogen Sulfide and T-Type Ca2+ Channels in Pain Processing, Neuronal Differentiation and Neuroendocrine Secretion.
Topics: Animals; Calcium Channels, T-Type; Cell Differentiation; Humans; Hydrogen Sulfide; Neuroendocrine Ce | 2017 |
Hydrogen sulfide and substance P in inflammation.
Topics: Air Pollutants; Amino Acid Sequence; Animals; Humans; Hydrogen Sulfide; Inflammation; Inflammation M | 2010 |
Luminal sulfide and large intestine mucosa: friend or foe?
Topics: Animals; Bacteria; Colitis, Ulcerative; Colon; Cystathionine gamma-Lyase; Energy Metabolism; Feces; | 2010 |
Interaction of hydrogen sulfide with ion channels.
Topics: Animals; ATP-Binding Cassette Transporters; Cytoprotection; Humans; Hydrogen Sulfide; Ion Channels; | 2010 |
Hydrogen sulfide-based therapies: focus on H2S releasing NSAIDs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Design | 2011 |
Hydrogen sulphide and pain.
Topics: Analgesics; Animals; Calcium Channels, T-Type; Disease Models, Animal; Humans; Hydrogen Sulfide; KAT | 2011 |
2 trials available for hydrogen sulfide and Pain
| Article | Year |
|---|---|
Potent anti-inflammatory effects of an H
Topics: Adolescent; Adult; Dinoprostone; Escherichia coli; Humans; Hydrogen Sulfide; Inflammation; Male; Mid | 2021 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
20 other studies available for hydrogen sulfide and Pain
| Article | Year |
|---|---|
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation.
Topics: Animals; Guinea Pigs; Hydrogen; Hydrogen Sulfide; Ligands; Male; Morpholines; Pain; Piperazines; Rat | 2022 |
Propargylglycine decreases neuro-immune interaction inducing pain response in temporomandibular joint inflammation model.
Topics: Alkynes; Animals; Cystathionine gamma-Lyase; Enzyme Inhibitors; Glycine; Hydrogen Sulfide; Hyperalge | 2019 |
Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats.
Topics: Algorithms; Alkynes; Animals; Blood Glucose; Cystathionine gamma-Lyase; Cysteine; Data Interpretatio | 2013 |
Inflammatory acidic pH enhances hydrogen sulfide-induced transient receptor potential ankyrin 1 activation in RIN-14B cells.
Topics: Animals; Cell Line; Hydrogen Sulfide; Hydrogen-Ion Concentration; Inflammation; Pain; Rats; Reactive | 2013 |
Upregulation of cystathionine-β-synthetase expression contributes to inflammatory pain in rat temporomandibular joint.
Topics: Action Potentials; Animals; Cystathionine beta-Synthase; Electric Stimulation; Enzyme Inhibitors; Fr | 2014 |
Anti-inflammatory and cytoprotective properties of hydrogen sulfide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cystathionine beta-Syntha | 2015 |
Hydrogen sulfide releasing naproxen offers better anti-inflammatory and chondroprotective effect relative to naproxen in a rat model of zymosan induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Hydrogen Sulfide; Injecti | 2015 |
Dual role of hydrogen sulfide in mechanical inflammatory hypernociception.
Topics: Analgesics; Animals; Cell Movement; Hydrogen Sulfide; Inflammation; KATP Channels; Male; Mice; Mice, | 2008 |
Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis.
Topics: Acute Disease; Animals; Arthritis; Behavior, Animal; Carrageenan; Cell Movement; Hydrogen Sulfide; K | 2008 |
Luminal hydrogen sulfide plays a pronociceptive role in mouse colon.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Capsaicin; Colon; Extracellular Signal- | 2009 |
Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain.
Topics: Analgesia; Analgesics; Animals; Cell Line; Disease Models, Animal; Humans; Hydrogen Sulfide; KATP Ch | 2010 |
Hydrogen sulfide: from physiology to pharmacology.
Topics: Animals; Anti-Inflammatory Agents; Cysteine; Disease Models, Animal; Drug Design; Humans; Hydrogen S | 2011 |
COXIBs, CINODs and H₂S-releasing NSAIDs: current perspectives in the development of safer non steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Gastrointestinal Hemorrhage; G | 2011 |
Hydrogen sulfide-induced colonic mucosal cytoprotection involves T-type calcium channel-dependent neuronal excitation in rats.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Capsaicin; Colitis; Colon; Cystathionin | 2012 |
The human operculo-insular cortex is pain-preferentially but not pain-exclusively activated by trigeminal and olfactory stimuli.
Topics: Adult; Benzaldehydes; Brain Mapping; Carbon Dioxide; Female; Humans; Hydrogen Sulfide; Magnetic Reso | 2012 |
Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice.
Topics: Acetanilides; Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels, T-Type; Cyclophos | 2012 |
A new extension to the University of Erlangen Smell Test (UEST).
Topics: Benzaldehydes; Carbon Dioxide; Evoked Potentials; Humans; Hydrogen Sulfide; Models, Biological; Mode | 2005 |
Hydrogen sulfide, is it a promise analgesic drug or another inflammatory pain mediator?
Topics: Analgesics; Animals; Humans; Hydrogen Sulfide; Inflammation Mediators; Pain | 2007 |
A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain.
Topics: Alkynes; Animals; Enzyme Inhibitors; Formaldehyde; Glycine; Hydrogen Sulfide; Inflammation; Irritant | 2008 |
[Effect of sulfide-hydrosulphide baths on sulfhydryl compounds in the serum of patients with cervical pains caused by discopathy treated at Busko-spa].
Topics: Female; Humans; Hydrogen Sulfide; Intervertebral Disc Displacement; Male; Mineral Waters; Neck; Pain | 1980 |