Page last updated: 2024-10-17

hydrogen sulfide and Neuralgia

hydrogen sulfide has been researched along with Neuralgia in 12 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Physiopathological mechanisms and treatment of pain remain a significant challenge."2.47Hydrogen sulphide and pain. ( Distrutti, E, 2011)
"The development of neuropathic pain was assessed using von Frey hair (mechanical allodynia), pinprick (mechanical hyperalgesia) and cold acetone drop tests (cold allodynia)."1.62Beneficial effects of octreotide in alcohol-induced neuropathic pain. Role of H 2S, BDNF, TNF-α and Nrf2. ( Jiang, R; Wei, H, 2021)
"Therapies to treat chronic neuropathic pain and its associated comorbidities are limited."1.56Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation. ( Batallé, G; Cabarga, L; Pol, O, 2020)
"Hydrogen sulfide (H2S) has recently been reported to be involved in numerous biological functions, and it has been shown that H2S can enhance the sodium current density, and inhibiting the endogenous production of H2S mediated by cystathionine β‑synthetase (CBS) using O‑(carboxymethyl)hydroxylamine hemihydrochloride (AOAA) can significantly reduce the expression of Nav1."1.56Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain. ( Chen, QY; Li, L; Ma, KT; Qu, ZW; Shi, WY; Si, JQ; Tan, CY; Tian, JJ; Zhang, M; Zhou, Y, 2020)
"Hydrogen sulfide plays important regulatory roles in different physiological and pathological conditions."1.51Nrf2/HO-1 signaling pathway participated in the protection of hydrogen sulfide on neuropathic pain in rats. ( Chen, H; Chen, Y; Lian, N; Wang, Y; Xie, K; Yu, Y; Zhang, K, 2019)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (75.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Cabarga, L1
Batallé, G1
Pol, O1
Tian, JJ1
Tan, CY1
Chen, QY1
Zhou, Y1
Qu, ZW1
Zhang, M1
Ma, KT1
Shi, WY1
Li, L1
Si, JQ1
Jiang, R1
Wei, H1
Lucarini, E1
Micheli, L1
Trallori, E1
Citi, V1
Martelli, A1
Testai, L1
De Nicola, GR1
Iori, R1
Calderone, V1
Ghelardini, C1
Di Cesare Mannelli, L1
Chen, H1
Xie, K1
Chen, Y1
Wang, Y2
Lian, N1
Zhang, K1
Yu, Y1
Terada, Y1
Kawabata, A4
Syhr, KMJ1
Boosen, M1
Hohmann, SW1
Longen, S1
Köhler, Y1
Pfeilschifter, J1
Beck, KF1
Geisslinger, G1
Schmidtko, A1
Kallenborn-Gerhardt, W1
Gui, Y1
Li, A1
Qiu, B1
Chen, F1
Chen, L1
Liu, D1
Chen, S1
Zhou, W1
Zhou, H1
Takahashi, T2
Aoki, Y1
Okubo, K2
Maeda, Y1
Sekiguchi, F2
Mitani, K1
Nishikawa, H1
Distrutti, E1
Kanaoka, D1
Matsunami, M1
Ohkubo, T1
Yamazaki, J1
Fukushima, N1
Yoshida, S1

Reviews

2 reviews available for hydrogen sulfide and Neuralgia

ArticleYear
H2S and Pain: A Novel Aspect for Processing of Somatic, Visceral and Neuropathic Pain Signals.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Calcium Channels; Calcium Channels, T-Type; Humans; Hydrogen Sulfide; Mice; Nerve Tissue Pr

2015
Hydrogen sulphide and pain.
    Inflammation & allergy drug targets, 2011, Volume: 10, Issue:2

    Topics: Analgesics; Animals; Calcium Channels, T-Type; Disease Models, Animal; Humans; Hydrogen Sulfide; KAT

2011

Other Studies

10 other studies available for hydrogen sulfide and Neuralgia

ArticleYear
Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Chronic Pain; Depression; Disease Models, Animal;

2020
Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain.
    International journal of molecular medicine, 2020, Volume: 46, Issue:2

    Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Hydrogen Sulfide; Male; Mitogen-Activated Prote

2020
Beneficial effects of octreotide in alcohol-induced neuropathic pain. Role of H 2S, BDNF, TNF-α and Nrf2.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:4

    Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Cystathionine beta-Synthase; Cystathionine g

2021
Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:11

    Topics: Animals; Antineoplastic Agents; Glucosinolates; Hydrogen Sulfide; Imidoesters; Isothiocyanates; KCNQ

2018
Nrf2/HO-1 signaling pathway participated in the protection of hydrogen sulfide on neuropathic pain in rats.
    International immunopharmacology, 2019, Volume: 75

    Topics: Animals; Cytokines; Heme Oxygenase (Decyclizing); Hydrogen Sulfide; Hyperalgesia; Male; Microglia; N

2019
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
    Brain research, 2015, Oct-22, Volume: 1624

    Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expr

2015
Endogenous CBS-H2S Pathway Contributes to the Development of CCI-Induced Neuropathic Pain.
    Neurochemical research, 2016, Volume: 41, Issue:6

    Topics: Animals; Constriction, Pathologic; Cystathionine beta-Synthase; Hydrogen Sulfide; Lumbar Vertebrae;

2016
Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain.
    Pain, 2010, Volume: 150, Issue:1

    Topics: Animals; Blotting, Western; Calcium Channel Blockers; Calcium Channels, T-Type; Hydrogen Sulfide; Hy

2010
Inhibition of T-type calcium channels and hydrogen sulfide-forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats.
    Neuroscience, 2011, Aug-11, Volume: 188

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Blotting, Western; Calcium Channels, T-Type; Cyclopr

2011
[Targeting Ca(v)3.2 T-type calcium channels as a therapeutic strategy for chemotherapy-induced neuropathic pain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 141, Issue:2

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Calcium Channels, T-Type; Dinoprostone; Humans; Hydro

2013