Page last updated: 2024-10-17

hydrogen sulfide and Neoplasms

hydrogen sulfide has been researched along with Neoplasms in 75 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Accumulating evidence suggests that abnormal levels of homocysteine are associated with vascular dysfunctions, cancer cell proliferation and various neurodegenerative diseases."7.83Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases. ( Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S, 2016)
"Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic homocysteine in the plasma."5.01Disturbed homocysteine metabolism is associated with cancer. ( Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR, 2019)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Accumulating evidence suggests that abnormal levels of homocysteine are associated with vascular dysfunctions, cancer cell proliferation and various neurodegenerative diseases."3.83Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases. ( Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S, 2016)
"They can stimulate or inhibit cancer cell proliferation and invasion, as well as interfere with cancer cell responses to drug treatments."2.82Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy (Review). ( Abdullah, RM; Al-Naqshabandi, MA; Alkasalias, T; Hama, HA; Housein, Z; Hussen, BM; Khudhur, ZO; Salihi, A, 2022)
"The preventable nature of cancer and the importance of a complex multi-level approach in anticancer therapy motivate the search for novel avenues of establishing the anticancer environment in the human body."2.72Postbiotics, Metabolic Signaling, and Cancer. ( Ruml, T; Vrzáčková, N; Zelenka, J, 2021)
"Though historically known as a toxic gas, hydrogen sulfide (H₂S) has displayed a new face as the third endogenous gaseous signaling molecule after nitric oxide (NO) and carbon monoxide (CO)."2.61Protective Smell of Hydrogen Sulfide and Polysulfide in Cisplatin-Induced Nephrotoxicity. ( Bian, J; Cao, X; Moore, PK; Zhang, W, 2019)
"Assays that could aid in cancer diagnostics, assessing anticancer drug resistance, and in the discovery of new anticancer drugs are highly warranted."2.58Fluorescent Chemosensors as Future Tools for Cancer Biology. ( Beharry, AA; Rotaru, AM; Singh, K, 2018)
"This is particularly evident in cancers of the colon and ovaries, where the malignant cells both overexpress cystathionine-β-synthase (CBS) and produce increased amounts of H2S, which enhances tumor growth and spread by (a) stimulating cellular bioenergetics, (b) activating proliferative, migratory, and invasive signaling pathways, and (c) enhancing tumor angiogenesis."2.52Hydrogen Sulfide and Cancer. ( Hellmich, MR; Szabo, C, 2015)
"In addition to promoting cancer cell death, H2S donors were also found to inhibit cancer angiogenesis and metastasis."2.52Role of H2S Donors in Cancer Biology. ( Deng, LW; Lee, ZW, 2015)
" sepsis), while in other disease states H2 S levels and H2 S bioavailability are reduced and its therapeutic replacement is warranted (e."2.50Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects. ( Bos, EM; Bouillaud, F; Calzia, E; Coletta, C; Hellmich, MR; Módis, K; Papapetropoulos, A; Radermacher, P; Szabo, C; van Goor, H, 2014)
"Hydrogen sulfide, H2S, is a colorless gas with a strong odor that until recently was only considered to be a toxic environmental pollutant with little or no physiological significance."2.49Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras. ( Kashfi, K; Olson, KR, 2013)
"Carbon monoxide (CO) is a gaseous product generated by heme oxygenase (HO), which oxidatively degrades heme."2.48Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implications. ( Hishiki, T; Kajimura, M; Kubo, A; Morikawa, T; Suematsu, M; Yamamoto, T, 2012)
"Imaging cancer specific biomarkers with near-infrared (NIR) fluorescent probes can help inaccurate diagnosis."1.91A biotin-guided near-infrared fluorescent probe for imaging hydrogen sulfide and differentiating cancer cells. ( Cai, X; Dong, Y; Hao, T; Yang, X; Yi, L; Zhang, Z, 2023)
"However, how MR impacts cancer progression in the context of the intact immune system is unknown."1.91Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota. ( Anantharaman, K; Andrea Azcarate-Peril, M; Arbeev, KG; Garcia-Peterson, LM; Hsiao, YC; Ji, M; Li, JL; Li, X; Liu, J; Lu, K; Martin, C; Popov, V; Randall, TA; Shats, I; Ukraintseva, S; Wan, Y; Wu, X; Xu, Q; Xu, X; Yashin, AI, 2023)
"Discovering and monitoring cancer markers are the main methods for early diagnosis of cancer."1.62Accurate Fluorescence Diagnosis of Cancer Based on Sequential Detection of Hydrogen Sulfide and pH. ( Fei, J; Jiang, WL; Li, CY; Li, Y; Mao, GJ; She, ZP; Wang, WX; Wang, ZQ, 2021)
"Therefore, an anticancer balance between pathological and protective immune response is urgently needed for an advanced photothermal therapeutic tactic."1.62Engineering a Hydrogen-Sulfide-Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy. ( Dai, Y; Fan, Q; Li, B; Li, J; Li, W; Sang, W; Tian, H; Wang, G; Xie, L; Yin, C; Zhang, X; Zhang, Z, 2021)
"Gas-involving cancer theranostics have attracted considerable attention in recent years due to their high therapeutic efficacy and biosafety."1.51Gas-Mediated Cancer Bioimaging and Therapy. ( Chen, L; Song, J; Su, L; Zhou, SF, 2019)
"In addition, it has been reported that cancer cells can produce large amounts of hydrogen sulfide (H2S) and their survival depends on the content of H2S."1.43Hydrogen Sulfide Triggered Charge-Reversal Micelles for Cancer-Targeted Drug Delivery and Imaging. ( Kong, X; Lin, W; Tang, Y; Zhang, H, 2016)
"Hydrogen sulfide (H2S) has emerged as an exciting endogenous gasotransmitter in addition to nitric oxide and carbon monoxide."1.42Visualization of in Vivo Hydrogen Sulfide Production by a Bioluminescence Probe in Cancer Cells and Nude Mice. ( Lau, C; Li, Z; Lu, J; Tian, X, 2015)
"Cancer and non-cancer cells were exposed to H2 S [using sodium hydrosulfide (NaHS) and GYY4137] and cell viability was examined by crystal violet assay."1.40Utilizing hydrogen sulfide as a novel anti-cancer agent by targeting cancer glycolysis and pH imbalance. ( Deng, LW; Hagen, T; Lee, ZW; Moore, PK; Tan, CH; Tay, EY; Teo, XY, 2014)
"To determine colorectal and overall cancer incidence as part of a three-pronged investigation in response to the concerns of a First Nations community in Alberta, Canada, located close to sulfur-rich natural gas installations, and to determine whether the incidence of cancers observed in this reserve was higher than expected."1.36An investigation of cancer incidence in a First Nations community in Alberta, Canada, 1995-2006. ( Ashbury, F; Chen, Y; Colquhoun, A; Drobina, W; Jiang, Z; Maiangowi, G; McLeod, L; Panaro, L; Sihota, S; Tustin, J; Yacoub, W, 2010)
"To assess mortality and cancer morbidity in Canadian petroleum workers and explore exposure-response relations for specific petroleum agents."1.32Mortality and cancer morbidity in a cohort of Canadian petroleum workers. ( Dahlman, D; Drummond, I; Jorgensen, G; Katz, AM; Lewis, RJ; Murray, N; Nicolich, MJ; Schnatter, AR; Thériault, G; Thompson, FS, 2003)
"Of the cancer sites, there was an elevated rate for nasal cancers."1.30Cancer incidence, morbidity and geothermal air pollution in Rotorua, New Zealand. ( Bates, MN; Garrett, N; Graham, B; Read, D, 1998)
"The incident cancers during this period were enumerated by computerized record linkage with the Alberta Cancer Registry."1.28Cancer downwind from sour gas refineries: the perception and the reality of an epidemic. ( Dales, RE; Eastridge, LM; Hobbs, C; Hutcheon, ME; Schechter, MT; Spitzer, WO; Steinmetz, N; Tousignant, P, 1989)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.00)18.7374
1990's2 (2.67)18.2507
2000's3 (4.00)29.6817
2010's34 (45.33)24.3611
2020's33 (44.00)2.80

Authors

AuthorsStudies
She, ZP1
Wang, WX2
Jiang, WL1
Wang, ZQ2
Mao, GJ2
Fei, J1
Li, Y3
Li, CY2
Jing, YZ1
Li, SJ1
Sun, ZJ1
Ding, H1
Chang, J1
He, F2
Gai, S2
Yang, P3
Liu, R1
Peng, Y1
Lu, L1
Peng, S1
Chen, T1
Zhan, M1
Yuan, J1
Ren, TB1
Xu, S1
Wang, CJ1
Zhang, XB1
Yuan, L1
Xiong, J1
Wang, Y2
Jiang, X1
Liang, X1
Liang, Q1
Li, J3
Xie, L2
Sang, W2
Li, W2
Wang, G2
Yan, J1
Zhang, Z3
Tian, H2
Fan, Q2
Dai, Y2
Salihi, A1
Al-Naqshabandi, MA1
Khudhur, ZO1
Housein, Z1
Hama, HA1
Abdullah, RM1
Hussen, BM1
Alkasalias, T1
Tan, ZK1
Chen, DH1
Khattak, S1
Rauf, MA1
Khan, NH1
Zhang, QQ1
Chen, HJ2
Muhammad, P1
Ansari, MA1
Alomary, MN1
Jahangir, M1
Zhang, CY1
Ji, XY2
Wu, DD2
Fan, Y1
Tan, X1
Zhao, H1
Tu, X1
Liu, X2
Li, G1
Lei, H1
Yang, Y2
Zhong, X1
Gong, F1
Gong, Y1
Zhou, Y1
Zhang, Y1
Shi, H1
Xiao, Z1
Dong, Z1
Cheng, L1
van der Vlies, AJ2
Ghasemi, M2
Adair, BM2
Adair, JH2
Gomez, ED2
Hasegawa, U2
Cai, X1
Dong, Y1
Hao, T1
Yi, L1
Yang, X1
Faris, P1
Negri, S1
Faris, D1
Scolari, F1
Montagna, D1
Moccia, F1
Kafuti, YS1
Zeng, S1
Han, J1
Qian, M1
Chen, Q2
Wang, J1
Peng, X2
Yoon, J1
Li, H1
Li, K1
Qin, YZ1
Zhou, JJ1
Li, T1
Qian, L1
Yang, CY1
Oza, PP1
Kashfi, K6
Ji, M1
Xu, X2
Xu, Q1
Hsiao, YC1
Martin, C1
Ukraintseva, S1
Popov, V1
Arbeev, KG1
Randall, TA1
Wu, X1
Garcia-Peterson, LM1
Liu, J1
Andrea Azcarate-Peril, M1
Wan, Y1
Yashin, AI1
Anantharaman, K1
Lu, K1
Li, JL1
Shats, I1
Li, X2
Chen, HY2
Xu, HB1
Lv, J1
Chang, S1
Wu, MS1
Chen, ZC1
Zhu, SC1
He, Y1
Qian, RC1
Li, DW1
Citi, V1
Barresi, E1
Piragine, E1
Spezzini, J1
Testai, L1
Da Settimo, F1
Martelli, A1
Taliani, S1
Calderone, V1
An, L1
Lin, J3
Tian, Q1
Yang, S1
Chen, L1
Zhou, SF1
Su, L1
Song, J1
Liu, Y1
Chen, H1
Cai, Y1
Sheng, T1
Wang, P1
Li, Z2
Yang, F1
Gu, N1
He, T1
Qin, X1
Jiang, C1
Jiang, D1
Lei, S1
Zhu, WG1
Qu, J1
Huang, P1
Zuhra, K2
Augsburger, F1
Majtan, T1
Szabo, C5
Zheng, Z1
Dai, R1
Jia, Z1
Yang, C1
Zhang, R1
Tomé, CS1
Forte, E1
Vicente, JB2
Giuffrè, A1
Bonifácio, VDB1
Pereira, SA1
Serpa, J1
Vrzáčková, N1
Ruml, T1
Zelenka, J1
Li, B1
Yin, C1
Zhang, X1
Liu, B1
Liang, S1
Wang, Z2
Sun, Q1
Cheng, Z1
Wang, RH1
Chu, YH1
Lin, KT1
Velusamy, N1
Binoy, A1
Bobba, KN1
Nedungadi, D1
Mishra, N1
Bhuniya, S1
Ma, Y2
Li, A1
Zhang, C1
Tang, B1
Singh, K1
Rotaru, AM1
Beharry, AA1
Ansari, MI1
Khan, MM1
Saquib, M1
Khatoon, S1
Hussain, MK1
Cao, X2
Ding, L1
Xie, ZZ1
Whiteman, M1
Moore, PK3
Bian, JS1
Zhu, H1
Blake, S1
Chan, KT1
Pearson, RB1
Kang, J1
Wu, L1
Sun, Y1
Sugimoto, K1
Luo, Z1
Ishigaki, Y1
Pu, K1
Suzuki, T1
Ye, D1
Zhang, W1
Bian, J1
Hasan, T1
Arora, R1
Bansal, AK1
Bhattacharya, R1
Sharma, GS1
Singh, LR1
Wang, H1
Su, S1
Chen, Y2
Wang, X1
Módis, K1
Bos, EM1
Calzia, E1
van Goor, H1
Coletta, C1
Papapetropoulos, A1
Hellmich, MR2
Radermacher, P1
Bouillaud, F1
Song, P1
Zou, MH1
Lee, ZW2
Teo, XY1
Tay, EY1
Tan, CH1
Hagen, T1
Deng, LW2
Lewis, RJ2
Copley, GB1
Bełtowski, J1
Tian, X1
Lau, C1
Lu, J1
De Preter, G1
Deriemaeker, C1
Danhier, P1
Brisson, L1
Cao Pham, TT1
Grégoire, V1
Jordan, BF1
Sonveaux, P1
Gallez, B1
Zhang, H1
Kong, X1
Tang, Y1
Lin, W1
Wu, Z1
Liang, D1
Tang, X1
Ciocci, M1
Iorio, E1
Carotenuto, F1
Khashoggi, HA1
Nanni, F1
Melino, S1
Padovani, D1
Hessani, A1
Castillo, FT1
Liot, G1
Andriamihaja, M1
Lan, A1
Pilati, C1
Blachier, F1
Sen, S1
Galardon, E1
Artaud, I1
Stroot, PG1
Miller, TW1
Isenberg, JS1
Roberts, DD1
Colquhoun, A1
Jiang, Z1
Maiangowi, G2
Ashbury, F2
Drobina, W1
McLeod, L1
Panaro, L1
Sihota, S1
Tustin, J1
Yacoub, W1
Chattopadhyay, M1
Kodela, R1
Nath, N1
Street, CR1
Velázquez-Martínez, CA1
Boring, D1
Hishiki, T1
Yamamoto, T1
Morikawa, T1
Kubo, A1
Kajimura, M1
Suematsu, M1
Olson, KR1
BARTH, G2
GRAEBNER, H2
Schnatter, AR1
Drummond, I1
Murray, N1
Thompson, FS1
Katz, AM1
Jorgensen, G1
Nicolich, MJ1
Dahlman, D1
Thériault, G1
Hansson, SO1
Bates, MN1
Garrett, N1
Graham, B1
Read, D1
Strickland, JA1
Foureman, GL1
Schechter, MT1
Spitzer, WO1
Hutcheon, ME1
Dales, RE1
Eastridge, LM1
Steinmetz, N1
Tousignant, P1
Hobbs, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091]Phase 220 participants (Anticipated)Interventional2019-08-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

31 reviews available for hydrogen sulfide and Neoplasms

ArticleYear
Gas and gas-generating nanoplatforms in cancer therapy.
    Journal of materials chemistry. B, 2021, 10-27, Volume: 9, Issue:41

    Topics: Antineoplastic Agents; Carbon Monoxide; Gases; Humans; Hydrogen; Hydrogen Sulfide; Mitochondria; Nan

2021
Hydrogen Sulfide: An Emerging Precision Strategy for Gas Therapy.
    Advanced healthcare materials, 2022, Volume: 11, Issue:4

    Topics: Humans; Hydrogen Sulfide; Nanomedicine; Nanostructures; Neoplasms; Signal Transduction

2022
Near-infrared light-triggered nano-prodrug for cancer gas therapy.
    Journal of nanobiotechnology, 2021, Dec-23, Volume: 19, Issue:1

    Topics: Animals; Gases; Humans; Hydrogen Sulfide; Infrared Rays; Nanostructures; Neoplasms; Nitric Oxide; Ph

2021
Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy (Review).
    Molecular medicine reports, 2022, Volume: 26, Issue:1

    Topics: Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulfide; Neoplasms; Nitric Oxide; Prospective St

2022
Hydrogen Sulfide Biology and Its Role in Cancer.
    Molecules (Basel, Switzerland), 2022, May-25, Volume: 27, Issue:11

    Topics: Animals; Biology; Cysteine; Hydrogen Sulfide; Mammals; Neoplasms; Signal Transduction

2022
Cysteine Metabolism in Tumor Redox Homeostasis.
    Current medicinal chemistry, 2023, Volume: 30, Issue:16

    Topics: Cysteine; Glutathione; Homeostasis; Humans; Hydrogen Sulfide; Neoplasms; Oxidation-Reduction; Qualit

2023
Recent advances in the role of endogenous hydrogen sulphide in cancer cells.
    Cell proliferation, 2023, Volume: 56, Issue:9

    Topics: Energy Metabolism; Humans; Hydrogen Sulfide; Neoplasms

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
The Triple Crown: NO, CO, and H
    Pharmacology & therapeutics, 2023, Volume: 249

    Topics: Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulfide; Neoplasms; Nitric Oxide

2023
Smart nanomedicine agents for cancer, triggered by pH, glutathione, H
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Glutathione; Humans; Hydrogen Peroxide; Hydrogen Sulfide; Hydrogen-Ion Concentration; Nanomedicine;

2019
Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition.
    Biomolecules, 2020, 04-30, Volume: 10, Issue:5

    Topics: Animals; Cystathionine beta-Synthase; Down Syndrome; Enzyme Inhibitors; Humans; Hydrogen Sulfide; Ne

2020
The multifaceted roles of sulfane sulfur species in cancer-associated processes.
    Biochimica et biophysica acta. Bioenergetics, 2021, 02-01, Volume: 1862, Issue:2

    Topics: Energy Metabolism; Humans; Hydrogen Sulfide; Neoplasms; Sulfur

2021
Cysteine metabolic circuitries: druggable targets in cancer.
    British journal of cancer, 2021, Volume: 124, Issue:5

    Topics: Animals; Cysteine; Energy Metabolism; Epigenesis, Genetic; Glycolysis; Humans; Hydrogen Sulfide; Met

2021
Hydrogen Sulfide, an Endogenous Stimulator of Mitochondrial Function in Cancer Cells.
    Cells, 2021, 01-22, Volume: 10, Issue:2

    Topics: Animals; DNA Repair; DNA, Mitochondrial; Humans; Hydrogen Sulfide; Mitochondria; Mitochondrial Dynam

2021
Postbiotics, Metabolic Signaling, and Cancer.
    Molecules (Basel, Switzerland), 2021, Mar-11, Volume: 26, Issue:6

    Topics: beta-Glucans; Butyrates; Dietary Supplements; Fatty Acids, Volatile; Gastrointestinal Microbiome; Hu

2021
The Hidden Role of Hydrogen Sulfide Metabolism in Cancer.
    International journal of molecular sciences, 2021, Jun-18, Volume: 22, Issue:12

    Topics: Animals; Humans; Hydrogen Sulfide; Neoplasms; Signal Transduction

2021
Fluorescent Chemosensors as Future Tools for Cancer Biology.
    ACS chemical biology, 2018, 07-20, Volume: 13, Issue:7

    Topics: Biology; Cell Line, Tumor; Enzymes; Fluorescent Dyes; Glutathione; High-Throughput Screening Assays;

2018
Dithiolethiones: a privileged pharmacophore for anticancer therapy and chemoprevention.
    Future medicinal chemistry, 2018, 05-01, Volume: 10, Issue:10

    Topics: Anticarcinogenic Agents; Drug Design; Humans; Hydrogen Sulfide; Neoplasms; NF-E2-Related Factor 2; N

2018
Cystathionine
    BioMed research international, 2018, Volume: 2018

    Topics: Carcinogenesis; Colon; Cystathionine beta-Synthase; Female; Humans; Hydrogen Sulfide; Neoplasms; Ova

2018
Protective Smell of Hydrogen Sulfide and Polysulfide in Cisplatin-Induced Nephrotoxicity.
    International journal of molecular sciences, 2019, Jan-14, Volume: 20, Issue:2

    Topics: Cisplatin; Cystathionine gamma-Lyase; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfi

2019
Disturbed homocysteine metabolism is associated with cancer.
    Experimental & molecular medicine, 2019, 02-21, Volume: 51, Issue:2

    Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predispos

2019
Anti-cancer activity of new designer hydrogen sulfide-donating hybrids.
    Antioxidants & redox signaling, 2014, Feb-10, Volume: 20, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Drug Scre

2014
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects.
    British journal of pharmacology, 2014, Volume: 171, Issue:8

    Topics: Animals; Diabetes Complications; Energy Metabolism; Gasotransmitters; Hibernation; Humans; Hydrogen

2014
Chronic low-level hydrogen sulfide exposure and potential effects on human health: a review of the epidemiological evidence.
    Critical reviews in toxicology, 2015, Volume: 45, Issue:2

    Topics: Air Pollutants; Cardiovascular Diseases; Dose-Response Relationship, Drug; Epidemiological Monitorin

2015
Hydrogen sulfide in pharmacology and medicine--An update.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:3

    Topics: Animals; Humans; Hydrogen Sulfide; Mitochondria; Neoplasms; Reperfusion Injury; Signal Transduction

2015
Hydrogen Sulfide and Cancer.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Cell Proliferation; Humans; Hydrogen Sulfide; Neoplasms

2015
Role of H2S Donors in Cancer Biology.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Humans; Hydrogen Sulfide; Neoplas

2015
Gasotransmitters in cancer: from pathophysiology to experimental therapy.
    Nature reviews. Drug discovery, 2016, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulfide; Neoplas

2016
Molecular regulation of tumor angiogenesis and perfusion via redox signaling.
    Chemical reviews, 2009, Volume: 109, Issue:7

    Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Carbon Monoxide; Humans; Hydrogen Peroxide; H

2009
Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implications.
    Journal of molecular medicine (Berlin, Germany), 2012, Volume: 90, Issue:3

    Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme Oxygenase (Decyclizing); Humans; Hydrogen Sulfide

2012
Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras.
    Biochemical pharmacology, 2013, Mar-01, Volume: 85, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemoprevention; Chimera; Humans; Hydrogen Sulfide

2013

Trials

1 trial available for hydrogen sulfide and Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

44 other studies available for hydrogen sulfide and Neoplasms

ArticleYear
Accurate Fluorescence Diagnosis of Cancer Based on Sequential Detection of Hydrogen Sulfide and pH.
    Analytical chemistry, 2021, 08-31, Volume: 93, Issue:34

    Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Mice; M

2021
A Unique Multifunctional Luminescent Probe for Self-Monitoring Photodynamic Therapy by Detecting H
    ACS applied bio materials, 2021, 08-16, Volume: 4, Issue:8

    Topics: Fluorescent Dyes; Hydrogen Sulfide; Luminescence; Neoplasms; Photochemotherapy; Reactive Oxygen Spec

2021
Kinetically Orthogonal Probe for Simultaneous Measurement of H
    Analytical chemistry, 2022, 01-25, Volume: 94, Issue:3

    Topics: Cell Count; Fluorescent Dyes; Humans; Hydrogen Sulfide; Neoplasms; Nitroreductases

2022
A Metal-Phenolic Nanosensitizer Performs Hydrogen Sulfide-Reprogrammed Oxygen Metabolism for Cancer Radiotherapy Intensification and Immunogenicity.
    Angewandte Chemie (International ed. in English), 2022, 04-25, Volume: 61, Issue:18

    Topics: Hafnium; Humans; Hydrogen Sulfide; Neoplasms; Oxygen; Polymers

2022
A nitrobenzoxadiazole-based near-infrared fluorescent probe for the specific imaging of H
    The Analyst, 2022, Jun-13, Volume: 147, Issue:12

    Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Mice; Neoplasms; Optical Imaging; Z

2022
Titanium Sulfide Nanosheets Serve as Cascade Bioreactors for H
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022, Volume: 9, Issue:30

    Topics: Adenosine Triphosphate; Bioreactors; Humans; Hydrogen Sulfide; Neoplasms; Reactive Oxygen Species

2022
Reactive Oxygen Species-Triggered Hydrogen Sulfide Release and Cancer-Selective Antiproliferative Effect of Anethole Dithiolethione-Containing Polymeric Micelles.
    Advanced healthcare materials, 2023, Volume: 12, Issue:6

    Topics: Endothelial Cells; Humans; Hydrogen Sulfide; Micelles; Neoplasms; Polymers; Reactive Oxygen Species

2023
Reactive Oxygen Species-Triggered Hydrogen Sulfide Release and Cancer-Selective Antiproliferative Effect of Anethole Dithiolethione-Containing Polymeric Micelles.
    Advanced healthcare materials, 2023, Volume: 12, Issue:6

    Topics: Endothelial Cells; Humans; Hydrogen Sulfide; Micelles; Neoplasms; Polymers; Reactive Oxygen Species

2023
Reactive Oxygen Species-Triggered Hydrogen Sulfide Release and Cancer-Selective Antiproliferative Effect of Anethole Dithiolethione-Containing Polymeric Micelles.
    Advanced healthcare materials, 2023, Volume: 12, Issue:6

    Topics: Endothelial Cells; Humans; Hydrogen Sulfide; Micelles; Neoplasms; Polymers; Reactive Oxygen Species

2023
Reactive Oxygen Species-Triggered Hydrogen Sulfide Release and Cancer-Selective Antiproliferative Effect of Anethole Dithiolethione-Containing Polymeric Micelles.
    Advanced healthcare materials, 2023, Volume: 12, Issue:6

    Topics: Endothelial Cells; Humans; Hydrogen Sulfide; Micelles; Neoplasms; Polymers; Reactive Oxygen Species

2023
A biotin-guided near-infrared fluorescent probe for imaging hydrogen sulfide and differentiating cancer cells.
    Organic & biomolecular chemistry, 2023, 01-04, Volume: 21, Issue:2

    Topics: Biotin; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Neoplasms; Optical Imaging

2023
Hydrogen Sulfide (H
    Current medicinal chemistry, 2023, Volume: 30, Issue:40

    Topics: Animals; Humans; Hydrogen Sulfide; Mammals; Neoplasms; Prodrugs; Signal Transduction

2023
Observing hydrogen sulfide in the endoplasmic reticulum of cancer cells and zebrafish by using an activity-based fluorescent probe.
    Chemical communications (Cambridge, England), 2023, Feb-23, Volume: 59, Issue:17

    Topics: Animals; Endoplasmic Reticulum; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Neoplasms; S

2023
Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota.
    Nature metabolism, 2023, Volume: 5, Issue:9

    Topics: Animals; Female; Gastrointestinal Microbiome; Hydrogen Sulfide; Male; Methionine; Mice; Neoplasms; R

2023
Smart Nanoplatform for Visualizing Hydrogen Sulfide and Amplifying Oxidative Stress to Tumor Apoptosis.
    ACS sensors, 2023, 09-22, Volume: 8, Issue:9

    Topics: Doxorubicin; Humans; Hydrogen Sulfide; Nanoparticles; Neoplasms; Oxidative Stress; Tumor Microenviro

2023
Anti-Proliferative Properties of the Novel Hybrid Drug Met-ITC, Composed of the Native Drug Metformin with the Addition of an Isothiocyanate H
    International journal of molecular sciences, 2023, Nov-09, Volume: 24, Issue:22

    Topics: Cell Line; Diabetes Mellitus, Type 2; Humans; Hydrogen Sulfide; Isothiocyanates; Metformin; Neoplasm

2023
Gas-Mediated Cancer Bioimaging and Therapy.
    ACS nano, 2019, 10-22, Volume: 13, Issue:10

    Topics: Carbon Dioxide; Carbon Monoxide; Gases; Humans; Hydrogen; Hydrogen Sulfide; Neoplasms; Nitric Oxide;

2019
Magnet-activatable nanoliposomes as intracellular bubble microreactors to enhance drug delivery efficacy and burst cancer cells.
    Nanoscale, 2019, Oct-28, Volume: 11, Issue:40

    Topics: Anethole Trithione; Hep G2 Cells; Humans; Hydrogen Sulfide; Liposomes; Magnetic Fields; Magnetic Res

2019
Tumor pH-responsive metastable-phase manganese sulfide nanotheranostics for traceable hydrogen sulfide gas therapy primed chemodynamic therapy.
    Theranostics, 2020, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Gases; Hyd

2020
Nitric oxide in cancer and beyond.
    Biochemical pharmacology, 2020, Volume: 176

    Topics: Congresses as Topic; Humans; Hydrogen Sulfide; Neoplasms; Nitric Oxide; Nitric Oxide Synthase Type I

2020
A continuous stimuli-responsive system for NIR-II fluorescence/photoacoustic imaging guided photothermal/gas synergistic therapy.
    Nanoscale, 2020, Jun-04, Volume: 12, Issue:21

    Topics: Allyl Compounds; Azides; Bismuth; Gases; Hydrogen Sulfide; Nanoparticles; Neoplasms; Optical Imaging

2020
Engineering a Hydrogen-Sulfide-Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:22

    Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Hydrogen Sulfide; Neoplasms

2021
A Tumor-Microenvironment-Responsive Nanocomposite for Hydrogen Sulfide Gas and Trimodal-Enhanced Enzyme Dynamic Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:30

    Topics: Animals; Chloride Peroxidase; Drug Carriers; Drug Liberation; Enzyme Activation; Female; Glutathione

2021
A bioorthogonal fluorescent probe for mitochondrial hydrogen sulfide: new strategy for cancer cell labeling.
    Chemical communications (Cambridge, England), 2017, Aug-11, Volume: 53, Issue:62

    Topics: Cell Line, Tumor; Cell Tracking; Coumarins; Cystathionine beta-Synthase; Cystathionine gamma-Lyase;

2017
H
    Angewandte Chemie (International ed. in English), 2017, 10-23, Volume: 56, Issue:44

    Topics: Animals; Cell Line, Tumor; HCT116 Cells; Hep G2 Cells; Humans; Hydrogen Sulfide; Metalloporphyrins;

2017
The role of hydrogen sulfide in health and disease.
    Biochemical pharmacology, 2018, Volume: 149

    Topics: Carbon Monoxide; Diabetes Mellitus; Gasotransmitters; Gastrointestinal Diseases; Gene Expression Reg

2018
A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?
    Antioxidants & redox signaling, 2019, 07-01, Volume: 31, Issue:1

    Topics: Animals; Biosynthetic Pathways; Cell Survival; Cystathionine beta-Synthase; Cystathionine gamma-Lyas

2019
Engineering of Electrochromic Materials as Activatable Probes for Molecular Imaging and Photodynamic Therapy.
    Journal of the American Chemical Society, 2018, 11-28, Volume: 140, Issue:47

    Topics: Aniline Compounds; Animals; Cell Line, Tumor; Drug Design; Female; Fluorescent Dyes; HEK293 Cells; H

2018
A red mitochondria-targeted AIEgen for visualizing H
    The Analyst, 2019, May-21, Volume: 144, Issue:10

    Topics: Animals; Drug Stability; Fluorescent Dyes; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen

2019
Redox regulation of endothelial cell fate.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:17

    Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Cell Movement; Cell Transdifferentiation; C

2014
Utilizing hydrogen sulfide as a novel anti-cancer agent by targeting cancer glycolysis and pH imbalance.
    British journal of pharmacology, 2014, Volume: 171, Issue:18

    Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Survival; Glucose; Glycolysis; Humans; Hydr

2014
Visualization of in Vivo Hydrogen Sulfide Production by a Bioluminescence Probe in Cancer Cells and Nude Mice.
    Analytical chemistry, 2015, Nov-17, Volume: 87, Issue:22

    Topics: Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Firefly Luciferin; Human

2015
A Fast Hydrogen Sulfide-Releasing Donor Increases the Tumor Response to Radiotherapy.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Femal

2016
Hydrogen Sulfide Triggered Charge-Reversal Micelles for Cancer-Targeted Drug Delivery and Imaging.
    ACS applied materials & interfaces, 2016, Jun-29, Volume: 8, Issue:25

    Topics: Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; HeLa Cells; Humans; Hydrogen Sulfi

2016
Visualizing Hydrogen Sulfide in Mitochondria and Lysosome of Living Cells and in Tumors of Living Mice with Positively Charged Fluorescent Chemosensors.
    Analytical chemistry, 2016, 09-20, Volume: 88, Issue:18

    Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Lysosomes; Mice; Mice, Nude; Micros

2016
H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Allyl Compounds; Antineoplastic Agents; Apoptosis; Cardiotonic Agents; Cell Cycle; Cell Line, Tumor;

2016
Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases.
    Nature communications, 2016, 11-16, Volume: 7

    Topics: Animals; Catalase; Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Activation; Heme;

2016
Blood oxidative stress (BLOS) is a secondary host defense system responding normally to anaerobic wound infection and inadvertently to dietary ultra-exogenous sulfide formation (USF).
    Medical hypotheses, 2017, Volume: 98

    Topics: Anaerobiosis; Animals; Atherosclerosis; Bacterial Infections; Blood Component Removal; Blood Glucose

2017
An investigation of cancer incidence in a First Nations community in Alberta, Canada, 1995-2006.
    Chronic diseases in Canada, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Alberta; Child; Child, Preschool; Colorectal Neoplasms; Environmental Exposure; F

2010
Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo.
    Biochemical pharmacology, 2012, Mar-15, Volume: 83, Issue:6

    Topics: Animals; Aspirin; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1A1; Gene Expression Reg

2012
[Observation on the formation of hydrogen sulfide in tumor irradiation. I].
    Strahlentherapie, 1962, Volume: 118

    Topics: Hydrogen Sulfide; Neoplasms; Radiation Effects

1962
[HYDROGEN SULFIDE DEVELOPMENT DURING TUMOR IRRADIATION. II. ATTEMPTED ALTERATION OF H2S FORMATION BY PARATUMORAL RUTIN THERAPY].
    Strahlentherapie, 1963, Volume: 122

    Topics: Animals; Hydrogen Sulfide; Hydrogen-Ion Concentration; Metabolism; Mice; Neoplasm Proteins; Neoplasm

1963
Mortality and cancer morbidity in a cohort of Canadian petroleum workers.
    Occupational and environmental medicine, 2003, Volume: 60, Issue:12

    Topics: Adult; Canada; Cause of Death; Cohort Studies; Extraction and Processing Industry; Female; Humans; H

2003
Critical effects and exposure limits.
    Risk analysis : an official publication of the Society for Risk Analysis, 1997, Volume: 17, Issue:2

    Topics: Acetone; Allergens; Animals; Caprolactam; Carcinogens; Central Nervous System Diseases; Dose-Respons

1997
Cancer incidence, morbidity and geothermal air pollution in Rotorua, New Zealand.
    International journal of epidemiology, 1998, Volume: 27, Issue:1

    Topics: Air Pollutants; Confidence Intervals; Ear Neoplasms; Ear, Middle; Ecology; Energy-Generating Resourc

1998
US EPA's acute reference exposure methodology for acute inhalation exposures.
    The Science of the total environment, 2002, Apr-08, Volume: 288, Issue:1-2

    Topics: Air Pollutants; Humans; Hydrocarbons, Chlorinated; Hydrogen Sulfide; Inhalation Exposure; Models, Th

2002
Cancer downwind from sour gas refineries: the perception and the reality of an epidemic.
    Environmental health perspectives, 1989, Volume: 79

    Topics: Acid Rain; Adult; Aged; Air Pollutants; Alberta; Cohort Studies; Cross-Sectional Studies; Female; Hu

1989