Page last updated: 2024-10-17

hydrogen sulfide and MODS

hydrogen sulfide has been researched along with MODS in 9 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
" To investigate hydrogen sulfide-mediated neurogenic inflammation in sepsis, DL-propargylglycine (50 mg/kg intraperitoneal), an inhibitor of hydrogen sulfide formation was administrated 1 hr before or 1 hr after the induction of sepsis, whereas sodium hydrosulfide (10 mg/kg intraperitoneal), a hydrogen sulfide donor, was given at the same time as cecal ligation and puncture."7.76Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis. ( Ang, SF; Bhatia, M; Moochhala, SM, 2010)
"Sepsis often leads to multiple organ failure or even death and is a significant health problem that contributes to a heavy economic burden."5.72Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury. ( Li, J; Li, L; Li, M; Ma, J; Yao, C; Yao, S, 2022)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."5.33Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. ( Anuar, FB; Bhatia, M; Collin, M; Moore, PK; Murch, O; Thiemermann, C, 2005)
" To investigate hydrogen sulfide-mediated neurogenic inflammation in sepsis, DL-propargylglycine (50 mg/kg intraperitoneal), an inhibitor of hydrogen sulfide formation was administrated 1 hr before or 1 hr after the induction of sepsis, whereas sodium hydrosulfide (10 mg/kg intraperitoneal), a hydrogen sulfide donor, was given at the same time as cecal ligation and puncture."3.76Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis. ( Ang, SF; Bhatia, M; Moochhala, SM, 2010)
"Sepsis often leads to multiple organ failure or even death and is a significant health problem that contributes to a heavy economic burden."1.72Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury. ( Li, J; Li, L; Li, M; Ma, J; Yao, C; Yao, S, 2022)
"Hydrogen sulfide (H2S) has been demonstrated to induce a "suspended animation-like" state in rodent models by reversible inhibition of cellular respiration and marked metabolic suppression and has been proposed as a potential pharmacologic adjunct to resuscitation from shock states."1.42Hydrogen sulfide improves resuscitation via non-hibernatory mechanisms in a porcine shock model. ( DeHart, MJ; Hempel, J; Hoffer, Z; Martin, M; Raywin, H; Salgar, S; Satterly, SA; Stallings, JD; Wingerd, M, 2015)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."1.33Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. ( Anuar, FB; Bhatia, M; Collin, M; Moore, PK; Murch, O; Thiemermann, C, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Li, J1
Li, M1
Li, L1
Ma, J1
Yao, C1
Yao, S1
Ahmad, A1
Druzhyna, N1
Szabo, C1
Reitsema, VA1
Star, BS1
de Jager, VD1
van Meurs, M1
Henning, RH1
Bouma, HR1
Suliman, HB1
Piantadosi, CA1
Satterly, SA1
Salgar, S1
Hoffer, Z1
Hempel, J1
DeHart, MJ1
Wingerd, M1
Raywin, H1
Stallings, JD1
Martin, M1
Ang, SF1
Moochhala, SM1
Bhatia, M2
Kapoor, A1
Thiemermann, C2
Tangerman, A1
Bongaerts, G1
Agbeko, R1
Semmekrot, B1
Severijnen, R1
Collin, M1
Anuar, FB1
Murch, O1
Moore, PK1

Reviews

2 reviews available for hydrogen sulfide and MODS

ArticleYear
Metabolic Resuscitation Strategies to Prevent Organ Dysfunction in Sepsis.
    Antioxidants & redox signaling, 2019, 07-10, Volume: 31, Issue:2

    Topics: Caloric Restriction; Combined Modality Therapy; Energy Metabolism; Humans; Hydrogen Sulfide; Hypothe

2019
Mitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stress.
    Current pharmaceutical design, 2014, Volume: 20, Issue:35

    Topics: Animals; Carbon Monoxide; Cell Survival; Energy Metabolism; Humans; Hydrogen Sulfide; Inflammation;

2014

Other Studies

7 other studies available for hydrogen sulfide and MODS

ArticleYear
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
    Molecular immunology, 2022, Volume: 141

    Topics: Acute Lung Injury; Animals; Autophagy; Cecum; Cell Line; Disease Models, Animal; Ferroptosis; Hydrog

2022
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
    Burns : journal of the International Society for Burn Injuries, 2017, Volume: 43, Issue:5

    Topics: Analysis of Variance; Animals; Biomarkers; Blotting, Western; Burns; Cystathionine gamma-Lyase; Cyto

2017
Hydrogen sulfide improves resuscitation via non-hibernatory mechanisms in a porcine shock model.
    The Journal of surgical research, 2015, Volume: 199, Issue:1

    Topics: Acidosis; Animals; Biomarkers; Cardiac Output; Combined Modality Therapy; Homeostasis; Hydrogen Sulf

2015
Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Alkynes; Animals; Capsaicin; Cystathionine gamma-Lyase; Glycine; Hydrogen Sulfide; Liver; Lung; Male

2010
Hydrogen sulfide, neurogenic inflammation, and cardioprotection: a tale of rotten eggs and vanilloid receptors.
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Liver; Lung; Mice;

2010
The origin of hydrogen sulfide in a newborn with sulfhaemoglobin induced cyanosis.
    Journal of clinical pathology, 2002, Volume: 55, Issue:8

    Topics: Cyanosis; Escherichia coli Infections; Fatal Outcome; Humans; Hydrogen Sulfide; Infant, Newborn; Mal

2002
Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.
    British journal of pharmacology, 2005, Volume: 146, Issue:4

    Topics: Alanine Transaminase; Alkynes; Analysis of Variance; Animals; Blood Pressure; Chemotaxis, Leukocyte;

2005