Page last updated: 2024-10-17

hydrogen sulfide and Liver Dysfunction

hydrogen sulfide has been researched along with Liver Dysfunction in 13 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"Cognitive dysfunction was detected in the hepatic I/R group, and this dysfunction was associated with a decrease in the mRNA and protein levels of the NR2B subunit of the NMDA receptors in the hippocampus."5.43Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats. ( Li, JX; Li, Q; Tu, FP; Wang, J, 2016)
"Hydrogen sulfide (H2S) can protect against hepatic ischemia-reperfusion injury (HIR)."3.83Silymarin preconditioning protected insulin resistant rats from liver ischemia-reperfusion injury: role of endogenous H2S. ( Mahmoud, MF; Shaheen, MA; Younis, NN, 2016)
"Hydrogen sulfide (H2S) is a gasotransmitter that regulates numerous physiological and pathophysiological processes in our body."2.50Hydrogen sulfide and the liver. ( Cao, W; Mani, S; Wang, R; Wu, L, 2014)
"Hydrogen sulfide (H(2)S) is a gas that can be formed by the action of two enzymes, cystathionine gamma lyase (CSE) and cystathionine beta synthase (CBS)."2.47Hydrogen sulfide in gastrointestinal and liver physiopathology. ( Cipriani, S; Mencarelli, A, 2011)
"Hydrogen sulfide has also been shown to play a key role in modulation of visceral hyperalgesia."2.43The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver. ( Cirino, G; Distrutti, E; Fiorucci, S; Wallace, JL, 2006)
"Cognitive dysfunction was detected in the hepatic I/R group, and this dysfunction was associated with a decrease in the mRNA and protein levels of the NR2B subunit of the NMDA receptors in the hippocampus."1.43Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats. ( Li, JX; Li, Q; Tu, FP; Wang, J, 2016)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."1.40Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation. ( Bekpinar, S; Gurdol, F; Unlucerci, Y; Uysal, M, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Lu, X1
Ding, Y1
Liu, H1
Sun, M1
Chen, C1
Yang, Y1
Wang, H1
Lee, JH1
Im, SS1
Khodosovskii, MN1
Mani, S1
Cao, W1
Wu, L1
Wang, R1
Bekpinar, S1
Unlucerci, Y1
Uysal, M1
Gurdol, F1
Zhao, H1
Ning, J1
Duan, J1
Gu, J1
Yi, B1
Lu, K1
Mo, L1
Lai, X1
Hennah, L1
Ma, D1
Younis, NN1
Shaheen, MA1
Mahmoud, MF1
Tu, FP1
Li, JX1
Li, Q1
Wang, J1
Chen, Y1
Liu, Z1
Xie, X1
Cipriani, S1
Mencarelli, A1
Iwakiri, Y1
Groszmann, RJ1
Fiorucci, S1
Distrutti, E1
Cirino, G1
Wallace, JL1
Friedman, MI1
Preti, G1
Deems, RO1
Friedman, LS1
Munoz, SJ1
Maddrey, WC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Concentration of Estrogen and Testosterone Ratio in Male Patients With Cirrhosis and Hypotension Compared to Male Cirrhosis Patients Without Hypotension[NCT05051293]0 participants (Actual)Observational2021-08-22Withdrawn (stopped due to Study will be changed from prospective to retrospective)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for hydrogen sulfide and Liver Dysfunction

ArticleYear
The Role of Hydrogen Sulfide Regulation of Autophagy in Liver Disorders.
    International journal of molecular sciences, 2022, Apr-06, Volume: 23, Issue:7

    Topics: Autophagy; Carbon Monoxide; Humans; Hydrogen Sulfide; Liver Diseases

2022
Function of gaseous hydrogen sulfide in liver fibrosis.
    BMB reports, 2022, Volume: 55, Issue:10

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Gases; Humans; Hydrogen Sulfide; Li

2022
Hydrogen sulfide and the liver.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Animals; Diabetes Mellitus; Glucose; Humans; Hydrogen Sulfide; Lipid Metabolism; Liver; Liver Diseas

2014
Hydrogen sulfide in gastrointestinal and liver physiopathology.
    Inflammation & allergy drug targets, 2011, Volume: 10, Issue:2

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Gastrointestinal Diseases; Gastroin

2011
The hyperdynamic circulation of chronic liver diseases: from the patient to the molecule.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:2 Suppl 1

    Topics: Adrenomedullin; Animals; Biological Factors; Blood Pressure; Cannabinoid Receptor Modulators; Carbon

2006
The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver.
    Gastroenterology, 2006, Volume: 131, Issue:1

    Topics: Air Pollutants; Animals; Chemical and Drug Induced Liver Injury; Gastrointestinal Diseases; Gastroin

2006

Other Studies

7 other studies available for hydrogen sulfide and Liver Dysfunction

ArticleYear
[INFLUENCE OF HYDROGEN SULFIDE ON BLOOD OXYGEN PARAMETERS DURING HEPATIC ISCHEMIA-REPERFUSION IN RATS].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:6

    Topics: Animals; Hydrogen Sulfide; Liver; Liver Diseases; Male; Oxygen; Rats; Reperfusion Injury

2016
Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:5

    Topics: Alkynes; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chromatography, High Press

2014
Regional traumatic limb hypothermia attenuates distant hepatic and renal injury following blast limb trauma in rats.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:3

    Topics: Animals; Blast Injuries; Hydrogen Sulfide; Hypothermia, Induced; Interleukin-6; Kidney; Kidney Disea

2014
Silymarin preconditioning protected insulin resistant rats from liver ischemia-reperfusion injury: role of endogenous H2S.
    The Journal of surgical research, 2016, Volume: 204, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Drug Evalu

2016
Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats.
    The Journal of surgical research, 2016, Volume: 205, Issue:2

    Topics: Animals; Biomarkers; Blotting, Western; Cognitive Dysfunction; Drug Administration Schedule; Hippoca

2016
Hydrogen sulphide attenuates renal and cardiac injury after total hepatic ischemia and reperfusion.
    The Journal of surgical research, 2010, Volume: 164, Issue:2

    Topics: Animals; Cell Adhesion Molecules; Enzyme-Linked Immunosorbent Assay; Hepatic Artery; Hydrogen Sulfid

2010
Limonene in expired lung air of patients with liver disease.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:8

    Topics: Air; Bilirubin; Breath Tests; Citrus; Cyclohexenes; Feeding Behavior; Female; Gas Chromatography-Mas

1994