Page last updated: 2024-10-17

hydrogen sulfide and Kidney Diseases

hydrogen sulfide has been researched along with Kidney Diseases in 32 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats."7.85Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017)
"Hydrogen sulfide has recently been found decreased in chronic kidney disease."5.40Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy. ( Hu, LF; Li, Q; Liu, CF; Peng, H; Shen, HY; Shi, YB; Song, K; Wang, F; Zheng, HF, 2014)
"The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats."3.85Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017)
" The aim of this study was to determine effects of inhibiting hydrogen sulphide biosynthesis by DL-propargyl glycine (an irreversible inhibitor of cystathionine gamma-lyase) on inflammation, necrosis and renal function, following treatment with gentamicin in rats."3.78Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity. ( Dam, VP; Kinobe, RT; Ross, A; Scott, JL, 2012)
"In this study we tested the hypothesis that H(2)S regulates collagen deposition, matrix metalloproteinases (MMP) and inflammatory molecules during hyperhomocysteinemia (HHcy) resulting in attenuation of glomerulosclerosis and improved renal function."3.76Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis. ( Abe, O; Gargoum, R; Munjal, C; Qipshidze, N; Sen, U; Tyagi, SC, 2010)
"The novel coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global pandemic which is primarily considered a respiratory illness."2.82Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy. ( Alornyo, KK; Antwi, S; Boima, V; Dugbartey, GJ; Ohene, BO; Sener, A, 2022)
"Though historically known as a toxic gas, hydrogen sulfide (H₂S) has displayed a new face as the third endogenous gaseous signaling molecule after nitric oxide (NO) and carbon monoxide (CO)."2.61Protective Smell of Hydrogen Sulfide and Polysulfide in Cisplatin-Induced Nephrotoxicity. ( Bian, J; Cao, X; Moore, PK; Zhang, W, 2019)
"Hypertension is the most common cause of cardiovascular morbidities and mortalities, and a major risk factor for renal dysfunction."2.55H ( Dugbartey, GJ, 2017)
"Hydrogen sulfide (H2S) has only recently gained recognition for its physiological effects."2.53Hydrogen Sulfide in Renal Physiology and Disease. ( Feliers, D; Kasinath, BS; Lee, HJ, 2016)
" However, a plethora of evidence indicates that nephrotoxicity is a major side effect of cisplatin therapy."2.53Hydrogen sulfide: A novel nephroprotectant against cisplatin-induced renal toxicity. ( Bouma, HR; Dugbartey, GJ; Lobb, I; Sener, A, 2016)
"Hydrogen sulfide has recently been found decreased in chronic kidney disease."1.40Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy. ( Hu, LF; Li, Q; Liu, CF; Peng, H; Shen, HY; Shi, YB; Song, K; Wang, F; Zheng, HF, 2014)
"Hydrogen sulfide is a gasotransmitter with far-reaching effects on cell function."1.40Hydrogen sulfide to the rescue in obstructive kidney injury. ( Kasinath, BS, 2014)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.13)29.6817
2010's28 (87.50)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Peleli, M1
Zampas, P1
Papapetropoulos, A1
Dugbartey, GJ3
Alornyo, KK1
Ohene, BO1
Boima, V1
Antwi, S1
Sener, A4
Piragine, E1
Malanima, MA1
Lucenteforte, E1
Martelli, A1
Calderone, V1
Siow, YL1
Li, L1
Xiao, T1
Li, F1
Li, Y1
Zeng, O1
Liu, M1
Liang, B1
Li, Z1
Chu, C1
Yang, J1
Kasinath, BS3
Feliers, D2
Lee, HJ2
Kashfi, K1
Hashmp, SF1
Sattar, MZA1
Rathore, HA1
Ahmadi, A1
Johns, EJ1
Hsu, CN1
Tain, YL1
Cao, X1
Zhang, W1
Moore, PK1
Bian, J1
Abdel-Zaher, AO1
Abd-Ellatief, RB1
Aboulhagag, NA1
Farghaly, HSM1
Al-Wasei, FMM1
Wang, SY1
Wang, WJ1
Liu, JQ1
Song, YH1
Li, P1
Sun, XF1
Cai, GY1
Chen, XM1
Jung, KJ1
Jang, HS1
Kim, JI1
Han, SJ1
Park, JW1
Park, KM1
Song, K1
Wang, F1
Li, Q1
Shi, YB1
Zheng, HF1
Peng, H1
Shen, HY1
Liu, CF1
Hu, LF1
Sen, U2
Pushpakumar, SB1
Amin, MA1
Tyagi, SC2
Pan, WJ1
Fan, WJ1
Zhang, C1
Han, D1
Qu, SL1
Jiang, ZS1
Zhao, H1
Ning, J1
Duan, J1
Gu, J1
Yi, B1
Lu, K1
Mo, L1
Lai, X1
Hennah, L1
Ma, D1
Lobb, I3
Sonke, E1
Aboalsamh, G1
Koning, AM1
Frenay, AR1
Leuvenink, HG2
van Goor, H2
Huang, P1
Shen, Z1
Liu, J1
Huang, Y1
Chen, S1
Yu, W1
Wang, S1
Ren, Y1
Li, X1
Tang, C1
Du, J1
Jin, H1
Bouma, HR1
Lin, S1
Visram, F1
Liu, W1
Haig, A1
Jiang, J1
Mok, A1
Lian, D1
Wood, ME1
Torregrossa, R1
Whiteman, M1
Bos, EM1
Snijder, PM1
Kloosterhuis, NJ1
Hillebrands, JL1
Leemans, JC1
Florquin, S1
Munjal, C1
Qipshidze, N1
Abe, O1
Gargoum, R1
Della Coletta Francescato, H1
Cunha, FQ1
Costa, RS1
Barbosa Júnior, F1
Boim, MA1
Arnoni, CP1
da Silva, CG1
Coimbra, TM1
Simon, F1
Scheuerle, A1
Gröger, M1
Stahl, B1
Wachter, U1
Vogt, J1
Speit, G1
Hauser, B1
Möller, P1
Calzia, E1
Szabó, C1
Schelzig, H1
Georgieff, M1
Radermacher, P1
Wagner, F1
Liu, YH1
Lu, M1
Bian, JS1
Yuzawa, Y1
Dam, VP1
Scott, JL1
Ross, A1
Kinobe, RT1

Reviews

17 reviews available for hydrogen sulfide and Kidney Diseases

ArticleYear
Hydrogen Sulfide and the Kidney: Physiological Roles, Contribution to Pathophysiology, and Therapeutic Potential.
    Antioxidants & redox signaling, 2022, Volume: 36, Issue:4-6

    Topics: Animals; Gasotransmitters; Hydrogen Sulfide; Kidney; Kidney Diseases; Mice; Signal Transduction

2022
Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy.
    Nitric oxide : biology and chemistry, 2022, 03-01, Volume: 120

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Hydrogen Sulfide; Kidney Diseases; SARS

2022
Circulating Levels of Hydrogen Sulfide (H
    Biomolecules, 2023, 06-21, Volume: 13, Issue:7

    Topics: Aged; Aging; Animals; Gasotransmitters; Humans; Hydrogen Sulfide; Hypertension; Kidney Diseases

2023
Metabolic Imbalance of Homocysteine and Hydrogen Sulfide in Kidney Disease.
    Current medicinal chemistry, 2018, 01-30, Volume: 25, Issue:3

    Topics: Animals; Homocysteine; Humans; Hydrogen Sulfide; Kidney Diseases

2018
Hydrogen sulfide as a regulatory factor in kidney health and disease.
    Biochemical pharmacology, 2018, Volume: 149

    Topics: Animals; Gasotransmitters; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases

2018
A CRITICAL REVIEW ON PHARMACOLOGICAL SIGNIFICANCE OF HYDROGEN SULFIDE (H₂S) ON NF-κB CONCENTRATION AND ICAM-1 EXPRESSION IN RENAL ISCHEMIA REPERFUSION INJURY.
    Acta poloniae pharmaceutica, 2017, Volume: 74, Issue:3

    Topics: Acute Kidney Injury; Animals; Humans; Hydrogen Sulfide; Intercellular Adhesion Molecule-1; Kidney; K

2017
Hydrogen Sulfide in Hypertension and Kidney Disease of Developmental Origins.
    International journal of molecular sciences, 2018, May-11, Volume: 19, Issue:5

    Topics: Animals; Antihypertensive Agents; Epigenesis, Genetic; Gene Expression Regulation; Humans; Hydrogen

2018
Protective Smell of Hydrogen Sulfide and Polysulfide in Cisplatin-Induced Nephrotoxicity.
    International journal of molecular sciences, 2019, Jan-14, Volume: 20, Issue:2

    Topics: Cisplatin; Cystathionine gamma-Lyase; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfi

2019
Homocysteine in renovascular complications: hydrogen sulfide is a modulator and plausible anaerobic ATP generator.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Adenosine Triphosphate; Anaerobiosis; Animals; Homocysteine; Humans; Hydrogen Sulfide; Kidney; Kidne

2014
H2S, a novel therapeutic target in renal-associated diseases?
    Clinica chimica acta; international journal of clinical chemistry, 2015, Jan-01, Volume: 438

    Topics: Animals; Humans; Hydrogen Sulfide; Kidney Diseases

2015
Hydrogen sulphide and the kidney: important roles in renal physiology and pathogenesis and treatment of kidney injury and disease.
    Nitric oxide : biology and chemistry, 2015, Apr-30, Volume: 46

    Topics: Animals; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases

2015
Hydrogen sulfide in renal physiology, disease and transplantation--the smell of renal protection.
    Nitric oxide : biology and chemistry, 2015, Apr-30, Volume: 46

    Topics: Animals; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases; Kidney Transplantation

2015
Hydrogen Sulfide in Renal Physiology and Disease.
    Antioxidants & redox signaling, 2016, 11-01, Volume: 25, Issue:13

    Topics: Animals; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases; Nitric Oxide; Oxidative Stress; Signal T

2016
Hydrogen sulfide: A novel nephroprotectant against cisplatin-induced renal toxicity.
    Nitric oxide : biology and chemistry, 2016, 07-01, Volume: 57

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Cisplatin; Humans

2016
H
    Nitric oxide : biology and chemistry, 2017, Apr-01, Volume: 64

    Topics: Animals; Antihypertensive Agents; Humans; Hydrogen Sulfide; Hypertension; Kidney Diseases; Mice

2017
Hydrogen sulfide and renal ischemia.
    Expert review of clinical pharmacology, 2011, Volume: 4, Issue:1

    Topics: Animals; Homocysteine; Humans; Hydrogen Sulfide; Ischemia; Kidney; Kidney Diseases; Signal Transduct

2011
[Role of hydrogen sulfide in chronic kidney disease and diabetic nephropathy].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2012, Volume: 139, Issue:1

    Topics: Animals; Chronic Disease; Diabetic Nephropathies; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Hy

2012

Other Studies

15 other studies available for hydrogen sulfide and Kidney Diseases

ArticleYear
Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats.
    Molecular medicine reports, 2017, Volume: 16, Issue:2

    Topics: Animals; Autophagy; Autophagy-Related Proteins; Collagen Type IV; Diabetes Mellitus, Experimental; F

2017
The role of hydrogen sulfide in health and disease.
    Biochemical pharmacology, 2018, Volume: 149

    Topics: Carbon Monoxide; Diabetes Mellitus; Gasotransmitters; Gastrointestinal Diseases; Gene Expression Reg

2018
The interrelationship between gasotransmitters and lead-induced renal toxicity in rats.
    Toxicology letters, 2019, Volume: 310

    Topics: Animals; Apoptosis; Carbon Monoxide; Caspase 3; Cytokines; Gasotransmitters; Heme Oxygenase (Decycli

2019
Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:14

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Caloric Restriction; Cell Line; Cellular Senescence;

2019
Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction.
    Biochimica et biophysica acta, 2013, Volume: 1832, Issue:12

    Topics: Animals; Blood Pressure; Blotting, Western; Cystathionine beta-Synthase; Cystathionine gamma-Lyase;

2013
Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy.
    Kidney international, 2014, Volume: 85, Issue:6

    Topics: Actins; Animals; Cell Line; Cell Proliferation; Collagen; Cystathionine beta-Synthase; Cystathionine

2014
Hydrogen sulfide to the rescue in obstructive kidney injury.
    Kidney international, 2014, Volume: 85, Issue:6

    Topics: Animals; Hydrogen Sulfide; Kidney; Kidney Diseases; Male; Sulfides; Ureteral Obstruction

2014
Regional traumatic limb hypothermia attenuates distant hepatic and renal injury following blast limb trauma in rats.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:3

    Topics: Animals; Blast Injuries; Hydrogen Sulfide; Hypothermia, Induced; Interleukin-6; Kidney; Kidney Disea

2014
Hydrogen Sulfide Inhibits High-Salt Diet-Induced Renal Oxidative Stress and Kidney Injury in Dahl Rats.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Antioxidants; Blood Pressure; Collagen; Hydrogen Sulfide; Kelch-Like ECH-Associated Protein

2016
GYY4137, a Slow-Releasing Hydrogen Sulfide Donor, Ameliorates Renal Damage Associated with Chronic Obstructive Uropathy.
    The Journal of urology, 2016, Volume: 196, Issue:6

    Topics: Animals; Chronic Disease; Hydrogen Sulfide; Kidney Diseases; Male; Morpholines; Organothiophosphorus

2016
Hydrogen sulfide-induced hypometabolism prevents renal ischemia/reperfusion injury.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:9

    Topics: Adaptation, Physiological; Air Pollutants; Animals; Disease Models, Animal; Energy Metabolism; Hiber

2009
Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis.
    American journal of nephrology, 2010, Volume: 31, Issue:5

    Topics: Animals; Collagen; Cystathionine beta-Synthase; Down-Regulation; Homocysteine; Hydrogen Sulfide; Hyp

2010
Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:2

    Topics: Alkynes; Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Enzyme Inhibitors; Glyci

2011
Effects of intravenous sulfide during porcine aortic occlusion-induced kidney ischemia/reperfusion injury.
    Shock (Augusta, Ga.), 2011, Volume: 35, Issue:2

    Topics: Air Pollutants; Animals; Aorta; bcl-X Protein; Caspase 3; Creatinine; Energy Metabolism; Female; Glo

2011
Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.
    European journal of pharmacology, 2012, Jun-15, Volume: 685, Issue:1-3

    Topics: Alkynes; Animals; Anti-Bacterial Agents; Cystathionine gamma-Lyase; Female; Gentamicins; Glycine; Hy

2012