hydrogen sulfide has been researched along with Innate Inflammatory Response in 258 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide is emerging as an important mediator of many aspects of inflammation, and perhaps most importantly as a factor promoting the resolution of inflammation and repair of injury." | 8.88 | Hydrogen sulfide: an endogenous mediator of resolution of inflammation and injury. ( Ferraz, JG; Muscara, MN; Wallace, JL, 2012) |
| "The view of hydrogen sulfide has changed from a toxic by-product to a crucial signaling molecule, with enormous potential as a pharmacological target for diseases ranging from heart disease to sepsis." | 8.88 | Hydrogen sulfide as a therapeutic target for inflammation. ( Badiei, A; Bhatia, M; Rivers, JR, 2012) |
| "Hydrogen sulfide is rapidly gaining ground as a physiological mediator of inflammation, but there is no clear consensus as to its precise role in inflammatory signaling." | 8.87 | Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising. ( Whiteman, M; Winyard, PG, 2011) |
| "Plasma homocysteine (Hcy) is an independent risk factor for Age related macular degeneration (AMD) and an inducer of inflammation." | 8.02 | Exogenous administration of hydrogen sulfide alleviates homocysteine induced inflammation in ARPE-19 cells. ( Chauhan, P; Kumaraswamy, A; Ravi, R; Subramaniam Rajesh, B, 2021) |
| "Previous studies have shown that during severe acute pancreatitis (SAP) attacks, hydrogen sulfide (H2S) is released in the colon." | 7.96 | Release of endogenous hydrogen sulfide in enteric nerve cells suppresses intestinal motility during severe acute pancreatitis. ( Liao, R; Liu, Y; Qiang, Z; Xue, L; Zhang, C, 2020) |
| "Atorvastatin significantly ameliorated renal dysfunction and morphological changes in CIAKI rats, as well as inflammation, apoptosis, and excessive oxidative stress." | 7.96 | Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide. ( Jiaqiong, L; Ming, L; Xiaoyong, L; Xinxue, L; Xuexian, T; Yan, L; Yinglan, L; Yue, G; Zena, H, 2020) |
| "We showed that hydrogen sulfide (H2S) inhibited IKKβ activation in the cell model of human PAEC inflammation induced by monocrotaline pyrrole-stimulation or knockdown of cystathionine γ-lyase (CSE), an H2S generating enzyme." | 7.91 | Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation. ( Bu, D; Chen, S; Du, J; Huang, Y; Jin, H; Kong, W; Liu, X; Tang, C; Tang, X; Tao, Y; Wang, X; Yang, G; Yu, W; Zhang, D; Zhang, H, 2019) |
| " The aim of the present study was to investigate whether exogenous hydrogen sulfide (H2S) protects against high glucose‑induced inflammation and cytotoxicity in cardiac cells by inhibiting the p38 mitogen‑activated protein kinase (MAPK)/nuclear factor‑κB (NF‑κB), cyclooxygenase‑2 (COX‑2) and inducible nitric oxide synthase (iNOS) signaling pathways." | 7.83 | Exogenous hydrogen sulfide protects against high glucose‑induced inflammation and cytotoxicity in H9c2 cardiac cells. ( Dong, X; Hu, X; Huang, Z; Liao, X; Wang, L; Zhuang, X, 2016) |
| "Exposure to ozone has been associated with airway inflammation, oxidative stress, and bronchial hyperresponsiveness." | 7.81 | Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness. ( Adcock, I; Chang, Y; Chung, KF; Gong, J; Hong, Y; Li, F; Wiegman, CH; Zhang, JJ; Zhang, M; Zhang, P; Zhou, X, 2015) |
| "The manner in which hydrogen sulfide (H2S) suppresses neuroinflammation is poorly understood." | 7.80 | CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. ( Alkayed, NJ; Ao, G; Cao, Y; Cheng, J; Hu, L; Jia, J; Jin, M; Liu, H; Wang, X; Wu, J; Zhen, X; Zheng, S; Zhou, X, 2014) |
| "Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation." | 7.80 | Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes. ( Blanco, FJ; Burguera, EF; Magalhães, J; Meijide-Faílde, R; Vela-Anero, A, 2014) |
| "Endogenous hydrogen sulfide (H2 S) may be a biomarker of asthma severity and activity." | 7.80 | Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2014) |
| "The present study was undertaken to study the effects of exogenous hydrogen sulfide (H(2)S) on global cerebral ischemia-reperfusion(I/R) and the underlying mechanisms." | 7.79 | Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative, anti-inflammatory and anti-apoptotic effects in rats. ( Chen, G; Liu, Y; Ou, D; Tu, C; Xiao, X; Yin, J; Zhao, J, 2013) |
| "The role of hydrogen sulfide (H2 S) in inflammation remains unclear with both pro- and anti-inflammatory actions of this gas described." | 7.79 | The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells. ( Fox, B; Keeble, J; Li, L; Moore, PK; Salto-Tellez, M; Whiteman, M; Winyard, PG; Wood, ME, 2013) |
| "The role of hydrogen sulfide (H(2)S) in endotoxin (lipopolysaccharide [LPS])-induced inflammation is incompletely understood." | 7.78 | Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice. ( Bougaki, M; Crimi, E; Ichinose, F; Khatri, A; Kida, K; Kimura, H; Marutani, E; Tokuda, K, 2012) |
| "Elevated level of homocysteine (Hcy) induces chronic inflammation in vascular bed, including glomerulus, and promotes glomerulosclerosis." | 7.77 | Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation. ( Abe, OA; Givvimani, S; Lederer, ED; Sen, U; Tyagi, SC, 2011) |
| "Hydrogen sulfide (H₂S), recently considered the third endogenous gaseous transmitter, may have an important role in systemic inflammation." | 7.77 | Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung. ( Chen, YH; He, YJ; Qi, YF; Tang, CS; Wang, PP; Wang, XM; Yao, WZ, 2011) |
| "Hydrogen sulfide (H(2)S) has been shown to induce transient receptor potential vanilloid 1 (TRPV1)-mediated neurogenic inflammation in polymicrobial sepsis." | 7.77 | Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling. ( Ang, SF; Bhatia, M; MacAry, PA; Moochhala, SM, 2011) |
| " NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression." | 7.77 | Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011) |
| "Endogenous hydrogen sulfide (H(2)S) is hypothesized to have an important role in systemic inflammation." | 7.75 | Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. ( Chen, YH; Geng, B; Qi, YF; Tang, CS; Wang, PP; Wu, R; Yao, WZ, 2009) |
| "To investigate the effects of hydrogen sulfide (H2S) on vascular inflammation and blood pressure in spontaneously hypertensive rats (SHR)." | 7.74 | [Hypotensive effects of hydrogen sulfide via attenuating vascular inflammation in spontaneously hypertensive rats]. ( DU, JB; Jin, HF; Liang, JM; Sun, Y; Tang, CS, 2008) |
| "Inflammation is a natural response to tissue injury." | 6.72 | Role of Hydrogen Sulfide, Substance P and Adhesion Molecules in Acute Pancreatitis. ( Bhatia, M; Kumar, A, 2021) |
| "Hydrogen sulfide is a novel gasotransmitter that has been shown to play a major role in regulating vascular tone." | 6.53 | The role of hydrogen sulfide in burns. ( Akter, F, 2016) |
| "Hydrogen sulfide (H(2)S) plays an important role in cardiovascular, central nervous, and gastrointestinal systems." | 6.46 | Hydrogen sulfide and substance P in inflammation. ( Bhatia, M, 2010) |
| "Atherosclerosis is a chronic, complex, and progressive pathological process in large and medium sized arteries." | 6.46 | Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis. ( Chaoshu, T; Hongfang, J; Junbao, D; Qiao, W, 2010) |
| "Chronic inflammation is a key factor that accelerates the progression of inflammatory vascular disease." | 5.91 | Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration. ( Lin, XL; Liu, MH; Xiao, LL, 2023) |
| "NaHS treatment decreased hypertension-induced Cx40/Cx43 expressions in T lymphocytes from SHR." | 5.48 | Hydrogen Sulfide Attenuates Hypertensive Inflammation via Regulating Connexin Expression in Spontaneously Hypertensive Rats. ( Li, L; Li, XZ; Ma, KT; Ni, X; Peng, M; Shan, LY; Shen, TW; Si, JQ; Yu, XS; Zhang, L, 2018) |
| "Hydrogen sulfide (H2S) has anti‑inflammatory and neuroprotective properties, particularly during pathological processes." | 5.46 | Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model. ( Han, Z; Huang, J; Jiang, P; Lun, Z; Xiao, B; Xu, J; Xu, Z; Zhou, W, 2017) |
| "Hydrogen sulfide (H2S) has attracted interest as a gaseous mediator involved in diverse processes in the nervous system, particularly with respect to learning and memory." | 5.43 | The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine. ( El Azhary, NM; Mostafa, DK; Nasra, RA, 2016) |
| "Hydrogen sulfide (H2S) functions as a protective gas transmitter in various physiological and pathological processes, but the lack of ideal donors severely hampers the clinical application of H2S." | 5.43 | Controlled release hydrogen sulfide delivery system based on mesoporous silica nanoparticles protects graft endothelium from ischemia-reperfusion injury. ( Guo, C; Liu, Y; Sun, X; Wang, C; Wang, W; Yang, C; Yang, W; Zhang, H, 2016) |
| "Airway inflammation was classified in 77 COPD subjects based on the presence of inflammatory cells in induced sputum." | 5.42 | Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2015) |
| "Hydrogen sulfide is a mediator of IRI and can ameliorate tissue injury in many organ systems." | 5.42 | Hydrogen sulfide reduces inflammation following abdominal aortic occlusion in rats. ( Furness, P; Hosgood, SA; Hunter, JP; Nicholson, ML; Patel, M; Sayers, RD, 2015) |
| "We developed a model of peritoneal fibrosis by intraperitoneally injecting 4." | 5.42 | Hydrogen Sulfide Alleviates Peritoneal Fibrosis via Attenuating Inflammation and TGF-β1 Synthesis. ( Gao, L; Li, L; Lu, Y; Shen, H; Song, K; Wang, Z; Zhu, Y, 2015) |
| "Hydrogen sulfide (H2S) has been proposed as a novel gas-transmittter, which plays multiple physiological and pathological functions in various body systems, including gastrointestinal tract." | 5.40 | Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway. ( Guo, C; Liang, F; Shah Masood, W; Yan, X, 2014) |
| "Hydrogen sulfide (H2S) is an important gaseous signaling agent mediated by many physiological processes and diseases." | 5.40 | Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model. ( Chen, W; Huang, L; Huang, W; Loo, JS; Pei, W; Wang, C; Yan, Q; Yao, C; Zhang, Q; Zhou, Y; Zhu, J, 2014) |
| "Hydrogen sulfide (H2S) is a gaseous mediator synthesized in mammalian tissues by three main enzymes-cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE), and 3-mercaptopyruvate-sulfurtransferase-and its levels increase under inflammatory conditions or sepsis." | 5.40 | Annexin A1 mediates hydrogen sulfide properties in the control of inflammation. ( Brancaleone, V; Cirino, G; Flower, RJ; Mitidieri, E; Perretti, M, 2014) |
| "Hydrogen sulfide is an essential gasotransmitter associated with numerous pathologies." | 5.38 | Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe. ( Dufton, N; Natividad, J; Verdu, EF; Wallace, JL, 2012) |
| "Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)." | 5.35 | Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008) |
| "There is a rapidly expanding body of evidence for important roles of hydrogen sulfide in protecting against tissue injury, reducing inflammation, and promoting repair." | 4.91 | Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics. ( Blackler, RW; Buret, AG; Chan, MV; Da Silva, GJ; Elsheikh, W; Flannigan, KL; Gamaniek, I; Manko, A; Motta, JP; Wallace, JL; Wang, L, 2015) |
| "Hydrogen sulfide is emerging as an important mediator of many aspects of inflammation, and perhaps most importantly as a factor promoting the resolution of inflammation and repair of injury." | 4.88 | Hydrogen sulfide: an endogenous mediator of resolution of inflammation and injury. ( Ferraz, JG; Muscara, MN; Wallace, JL, 2012) |
| "The view of hydrogen sulfide has changed from a toxic by-product to a crucial signaling molecule, with enormous potential as a pharmacological target for diseases ranging from heart disease to sepsis." | 4.88 | Hydrogen sulfide as a therapeutic target for inflammation. ( Badiei, A; Bhatia, M; Rivers, JR, 2012) |
| "Hydrogen sulfide is rapidly gaining ground as a physiological mediator of inflammation, but there is no clear consensus as to its precise role in inflammatory signaling." | 4.87 | Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising. ( Whiteman, M; Winyard, PG, 2011) |
| " The pharmacological profiles of some hybrid lead compounds in the areas of inflammation, H(2)S-donating diclofenac (ACS 15); cardiovascular, H(2)S-donating aspirin (ACS 14); urology, H(2)S-donating sildenafil (ACS 6); and neurodegenerative, H(2)S-donating latanoprost (ACS 67) for glaucoma treatment and H(2)S-donating levodopa (ACS 84) for Parkinson's disease, are described." | 4.87 | Therapeutic potential of new hydrogen sulfide-releasing hybrids. ( Del Soldato, P; Giustarini, D; Rossi, R; Santus, G; Sparatore, A, 2011) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "To investigate the effect of hydrogen sulfide (H2S) on myocardial injury in sepsis-induced myocardial dysfunction (SIMD), male C57BL/6 mice were intraperitoneally injected with lipopolysaccharide (LPS) (10 mg/kg, i." | 4.31 | Hydrogen sulfide alleviates lipopolysaccharide-induced myocardial injury through TLR4-NLRP3 pathway. ( Bai, L; He, K; Jin, S; Liu, B; Miao, Y; Wu, Y; Xia, Y; Zhang, W; Zhang, X, 2023) |
| "Transient molecules in the gastrointestinal tract such as nitric oxide and hydrogen sulfide are key signals and mediators of inflammation." | 4.31 | Sub-1.4 cm ( Ahn, J; Chandrakasan, AP; Fabian, N; Hayward, A; Inda-Webb, ME; Ishida, K; Jenkins, J; Jimenez, M; Kuosmanen, J; Lai, Y; Liu, Q; Lu, TK; Madani, W; McNally, R; Mimee, M; Nadeau, P; Phan, NV; Riaz, A; Steiger, C; Traverso, G; Wentworth, A; Wong, K; Yazicigil, RT; Zirtiloglu, T, 2023) |
| "Plasma homocysteine (Hcy) is an independent risk factor for Age related macular degeneration (AMD) and an inducer of inflammation." | 4.02 | Exogenous administration of hydrogen sulfide alleviates homocysteine induced inflammation in ARPE-19 cells. ( Chauhan, P; Kumaraswamy, A; Ravi, R; Subramaniam Rajesh, B, 2021) |
| "Previous studies have shown that during severe acute pancreatitis (SAP) attacks, hydrogen sulfide (H2S) is released in the colon." | 3.96 | Release of endogenous hydrogen sulfide in enteric nerve cells suppresses intestinal motility during severe acute pancreatitis. ( Liao, R; Liu, Y; Qiang, Z; Xue, L; Zhang, C, 2020) |
| "Based on the obtained results we believe that our transcriptomic analysis significantly contributes to the understanding of the molecular mechanisms of anti-inflammatory and cytoprotective activity of hydrogen sulfide donors, and highlights their potential against LPS challenges and other forms of inflammation." | 3.96 | H ( Chuvakova, LN; Evgen'ev, MB; Funikov, SY; Krasnov, GS; Kulikova, DA; Morozov, AV; Rezvykh, AP; Vinokurov, MG; Yurinskaya, MM; Zatsepina, OG, 2020) |
| "Atorvastatin significantly ameliorated renal dysfunction and morphological changes in CIAKI rats, as well as inflammation, apoptosis, and excessive oxidative stress." | 3.96 | Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide. ( Jiaqiong, L; Ming, L; Xiaoyong, L; Xinxue, L; Xuexian, T; Yan, L; Yinglan, L; Yue, G; Zena, H, 2020) |
| "We showed that hydrogen sulfide (H2S) inhibited IKKβ activation in the cell model of human PAEC inflammation induced by monocrotaline pyrrole-stimulation or knockdown of cystathionine γ-lyase (CSE), an H2S generating enzyme." | 3.91 | Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation. ( Bu, D; Chen, S; Du, J; Huang, Y; Jin, H; Kong, W; Liu, X; Tang, C; Tang, X; Tao, Y; Wang, X; Yang, G; Yu, W; Zhang, D; Zhang, H, 2019) |
| " Endogenous hydrogen sulfide (H2S) has roles including regulating inflammation, and promoting vasodilatation; it also exhibits anti-oxidative stress and anti-fibrosis effects." | 3.91 | Hydrogen sulfide treatment alleviated ventilator-induced lung injury through regulation of autophagy and endoplasmic reticulum stress. ( Fei, A; Gao, C; Ge, X; Pan, S; Sun, J; Wu, Z, 2019) |
| "Neuro-inflammation plays a critical role in hyperhomocysteinemia (HHcy)-associated neurodegenerative disorders." | 3.91 | Hydrogen sulfide suppresses homocysteine-induced glial activation and inflammatory response. ( Kumar, M; Sandhir, R, 2019) |
| " Hydrogen sulfide, synthesized from L-cysteine by two key enzymes, cystathionine-β-synthase (CBS) and cystathionine-γ-lysase (CSE) is reported to play a key role in regulating gastrointestinal motility and promoting resolution of inflammation." | 3.88 | Reduction of hydrogen sulfide synthesis enzymes cystathionine-β-synthase and cystathionine-γ-lyase in the colon of patients with Hirschsprungs disease. ( Coyle, D; O'Donnell, AM; Puri, P; Tomuschat, C, 2018) |
| "Previous studies have suggested that exogenous hydrogen sulfide can alleviate the development of diabetic cardiomyopathy (DCM) by inhibiting oxidative stress, inflammation, and apoptosis." | 3.88 | Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway. ( Chao, YL; Chen, SL; Gu, Y; Kong, XQ; Luo, J; Ren, XM; Ye, P; Zhang, DM; Zhu, YR; Zuo, GF, 2018) |
| " Besides H2S production rate and protein expressions of H2S-related synthases cystathionine β-synthase (CBS), 3-mercaptopyruvate sulfurtransferase (3-MPST) and cystathionine γ-lyase (CSE) in the POA, we also measured deep body temperature (Tb), circulating plasma levels of cytokines and corticosterone in an animal model of systemic inflammation." | 3.85 | Effect of Physical Exercise on the Febrigenic Signaling is Modulated by Preoptic Hydrogen Sulfide Production. ( Antunes-Rodrigues, J; Branco, LG; Coimbra, TM; Fernandez, RA; Francescato, HD; Nogueira, JE; Saia, RS; Soriano, RN, 2017) |
| "A panel of 23 stable COPD patients was repeatedly measured for biomarkers of airway inflammation including exhaled nitric oxide (FeNO) and exhaled hydrogen sulfide (FeH2S) (215 measurements) and recorded for daily respiratory symptoms (794person-days) in two study periods in Beijing, China in January-September 2014." | 3.83 | Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China. ( Baccarelli, AA; Chen, Y; Deng, F; Guo, X; Li, H; Ni, Y; Pan, L; Shima, M; Wu, S; Yang, D, 2016) |
| "Accumulating evidence demonstrated that hydrogen sulfide (H2S) is highly involved in inflammation, oxidative stress, and apoptosis and contributes to the pathogenesis of kidney diseases." | 3.83 | A H 2 S Donor GYY4137 Exacerbates Cisplatin-Induced Nephrotoxicity in Mice. ( Jia, Z; Liu, M; Sun, Y; Yang, T; Zhang, A, 2016) |
| " The aim of the present study was to investigate whether exogenous hydrogen sulfide (H2S) protects against high glucose‑induced inflammation and cytotoxicity in cardiac cells by inhibiting the p38 mitogen‑activated protein kinase (MAPK)/nuclear factor‑κB (NF‑κB), cyclooxygenase‑2 (COX‑2) and inducible nitric oxide synthase (iNOS) signaling pathways." | 3.83 | Exogenous hydrogen sulfide protects against high glucose‑induced inflammation and cytotoxicity in H9c2 cardiac cells. ( Dong, X; Hu, X; Huang, Z; Liao, X; Wang, L; Zhuang, X, 2016) |
| "Exposure to ozone has been associated with airway inflammation, oxidative stress, and bronchial hyperresponsiveness." | 3.81 | Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness. ( Adcock, I; Chang, Y; Chung, KF; Gong, J; Hong, Y; Li, F; Wiegman, CH; Zhang, JJ; Zhang, M; Zhang, P; Zhou, X, 2015) |
| " Since then, studies on hydrogen sulfide (H2S) have uncovered its numerous physiological roles such as protecting various tissues/organs from ischemia and regulating inflammation, cell growth, oxygen sensing, and senescence." | 3.81 | H2S2014 in Kyoto: the 3rd International Conference on H2S in Biology and Medicine. ( Kimura, H, 2015) |
| " It has been demonstrated that hydrogen sulfide (H2S) exerts an inhibitory effect on inflammation." | 3.81 | Hydrogen sulfide attenuates IL-1β-induced inflammatory signaling and dysfunction of osteoarthritic chondrocytes. ( Ha, C; Lv, J; Sun, K; Tian, S; Wang, D; Wang, Y, 2015) |
| "Hydrogen sulfide (H2S), an endogenous gaseotransmitter/modulator, is becoming appreciated that it may be involved in a wide variety of processes including inflammation and nociception." | 3.80 | Upregulation of cystathionine-β-synthetase expression contributes to inflammatory pain in rat temporomandibular joint. ( Hu, S; Ju, Z; Meng, X; Miao, X; Wu, G; Xu, GY; Zhang, HH, 2014) |
| "The manner in which hydrogen sulfide (H2S) suppresses neuroinflammation is poorly understood." | 3.80 | CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. ( Alkayed, NJ; Ao, G; Cao, Y; Cheng, J; Hu, L; Jia, J; Jin, M; Liu, H; Wang, X; Wu, J; Zhen, X; Zheng, S; Zhou, X, 2014) |
| "Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation." | 3.80 | Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes. ( Blanco, FJ; Burguera, EF; Magalhães, J; Meijide-Faílde, R; Vela-Anero, A, 2014) |
| "Accumulating evidence has demonstrated that hydrogen sulfide (H2S) plays critical roles in the pathogenesis of chronic kidney diseases." | 3.80 | Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model. ( Chen, J; Feng, Y; Zhan, Z; Zhou, X, 2014) |
| "Endogenous hydrogen sulfide (H2 S) may be a biomarker of asthma severity and activity." | 3.80 | Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2014) |
| "We have demonstrated the neuroprotection of hydrogen sulfide (H2S) against chemical hypoxia-induced injury by inhibiting p38MAPK pathway." | 3.79 | Inhibition of ROS-activated p38MAPK pathway is involved in the protective effect of H2S against chemical hypoxia-induced inflammation in PC12 cells. ( Feng, J; Guo, R; Hu, F; Hua, X; Lan, A; Liu, D; Shen, N; Xu, W; Zhang, H; Zheng, D, 2013) |
| "The present study was undertaken to study the effects of exogenous hydrogen sulfide (H(2)S) on global cerebral ischemia-reperfusion(I/R) and the underlying mechanisms." | 3.79 | Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative, anti-inflammatory and anti-apoptotic effects in rats. ( Chen, G; Liu, Y; Ou, D; Tu, C; Xiao, X; Yin, J; Zhao, J, 2013) |
| "The role of hydrogen sulfide (H2 S) in inflammation remains unclear with both pro- and anti-inflammatory actions of this gas described." | 3.79 | The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells. ( Fox, B; Keeble, J; Li, L; Moore, PK; Salto-Tellez, M; Whiteman, M; Winyard, PG; Wood, ME, 2013) |
| "The role of hydrogen sulfide (H(2)S) in endotoxin (lipopolysaccharide [LPS])-induced inflammation is incompletely understood." | 3.78 | Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice. ( Bougaki, M; Crimi, E; Ichinose, F; Khatri, A; Kida, K; Kimura, H; Marutani, E; Tokuda, K, 2012) |
| " The aim of this study was to determine effects of inhibiting hydrogen sulphide biosynthesis by DL-propargyl glycine (an irreversible inhibitor of cystathionine gamma-lyase) on inflammation, necrosis and renal function, following treatment with gentamicin in rats." | 3.78 | Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity. ( Dam, VP; Kinobe, RT; Ross, A; Scott, JL, 2012) |
| "Inhaling hydrogen sulfide (H2S) reduced energy expenditure resulting in hypothermia." | 3.77 | Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock. ( Asfar, P; Calzia, E; Gebhard, F; Georgieff, M; Huber-Lang, M; Hysa, V; Knöferl, MW; Radermacher, P; Seitz, DH; Senftleben, U; Stahl, B; Wagner, F; Wagner, K; Weber, S, 2011) |
| "Elevated level of homocysteine (Hcy) induces chronic inflammation in vascular bed, including glomerulus, and promotes glomerulosclerosis." | 3.77 | Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation. ( Abe, OA; Givvimani, S; Lederer, ED; Sen, U; Tyagi, SC, 2011) |
| "Hydrogen sulfide (H₂S), recently considered the third endogenous gaseous transmitter, may have an important role in systemic inflammation." | 3.77 | Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung. ( Chen, YH; He, YJ; Qi, YF; Tang, CS; Wang, PP; Wang, XM; Yao, WZ, 2011) |
| "Hydrogen sulfide (H(2)S) has been shown to induce transient receptor potential vanilloid 1 (TRPV1)-mediated neurogenic inflammation in polymicrobial sepsis." | 3.77 | Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling. ( Ang, SF; Bhatia, M; MacAry, PA; Moochhala, SM, 2011) |
| " NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression." | 3.77 | Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011) |
| "In this study we tested the hypothesis that H(2)S regulates collagen deposition, matrix metalloproteinases (MMP) and inflammatory molecules during hyperhomocysteinemia (HHcy) resulting in attenuation of glomerulosclerosis and improved renal function." | 3.76 | Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis. ( Abe, O; Gargoum, R; Munjal, C; Qipshidze, N; Sen, U; Tyagi, SC, 2010) |
| "L-cysteine or sodium hydrogen sulphide (NaHS) was injected into the mouse hind paw and oedema formation was evaluated for 60 min." | 3.76 | Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2. ( Bucci, M; Cirino, G; Coletta, C; De Dominicis, G; di Villa Bianca, Rd; Mitidieri, E; Rossi, A; Sautebin, L; Sorrentino, R, 2010) |
| "Endogenous hydrogen sulfide (H(2)S) is hypothesized to have an important role in systemic inflammation." | 3.75 | Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. ( Chen, YH; Geng, B; Qi, YF; Tang, CS; Wang, PP; Wu, R; Yao, WZ, 2009) |
| "Hydrogen sulfide (H2S) displays anti-inflammatory and cytoprotective activities as evidenced by the inhibition of myocardial ischemia-reperfusion injury and production of lipid peroxidation." | 3.75 | Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats. ( Jiang, H; Kang, K; Pan, S; Sun, X; Tan, G; Zhao, M, 2009) |
| "To investigate the effects of hydrogen sulfide (H2S) on vascular inflammation and blood pressure in spontaneously hypertensive rats (SHR)." | 3.74 | [Hypotensive effects of hydrogen sulfide via attenuating vascular inflammation in spontaneously hypertensive rats]. ( DU, JB; Jin, HF; Liang, JM; Sun, Y; Tang, CS, 2008) |
| "The present study investigated the hypothesis that hydrogen sulfide (H2S) is pro-nociceptive in the formalin model of persistent inflammatory pain in the adult rat." | 3.74 | A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain. ( Cheng, Y; Khanna, S; Lee, AT; Li, L; Moore, PK; Shah, JJ, 2008) |
| "Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by fatty lesions and fat accumulation in hepatic parenchymal cells, which is in the absence of excessive alcohol consumption or definite liver damage factors." | 3.01 | Gasotransmitters in non-alcoholic fatty liver disease: just the tip of the iceberg. ( Chen, YQ; Kong, GY; Li, AH; Li, JX; Li, Y; Nan, JX; Wang, Q; Yuan, S; Zhang, HM; Zhang, QG, 2023) |
| "Inflammation is a natural response to tissue injury." | 2.72 | Role of Hydrogen Sulfide, Substance P and Adhesion Molecules in Acute Pancreatitis. ( Bhatia, M; Kumar, A, 2021) |
| "Hydrogen sulfide is a novel gasotransmitter that has been shown to play a major role in regulating vascular tone." | 2.53 | The role of hydrogen sulfide in burns. ( Akter, F, 2016) |
| "Inflammation is a response to traumatic, infectious, post-ischemic, toxic, or autoimmune injury." | 2.52 | H2S and Inflammation: An Overview. ( Bhatia, M, 2015) |
| "Hydrogen sulfide (H(2)S) has recently emerged as a mammalian gaseous messenger molecule, akin to nitric oxide and carbon monoxide." | 2.48 | H₂S signalling through protein sulfhydration and beyond. ( Paul, BD; Snyder, SH, 2012) |
| "Hydrogen sulfide (H(2)S) has been classified as a third novel gasotransmitter signaling molecule alongside nitric oxide and carbon monoxide." | 2.47 | Hydrogen sulfide gas has cell growth regulatory role. ( Baskar, R; Bian, J, 2011) |
| "H2S (hydrogen sulfide) is a well known and pungent gas recently discovered to be synthesized enzymatically in mammalian and human tissues." | 2.47 | Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools. ( Chopra, M; Fox, B; Le Trionnaire, S; Whatmore, J; Whiteman, M, 2011) |
| "Hydrogen sulfide (H(2)S) plays an important role in cardiovascular, central nervous, and gastrointestinal systems." | 2.46 | Hydrogen sulfide and substance P in inflammation. ( Bhatia, M, 2010) |
| "Atherosclerosis is a chronic, complex, and progressive pathological process in large and medium sized arteries." | 2.46 | Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis. ( Chaoshu, T; Hongfang, J; Junbao, D; Qiao, W, 2010) |
| " Finally, in addition to the question of dosing and timing (for example, bolus administration versus continuous intravenous infusion), the preferred route of H2S administration remains to be settled--that is, inhaling gaseous H2S versus intra-venous administration of injectable H2S preparations or H2S donors." | 2.45 | Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care. ( Asfar, P; Calzia, E; Radermacher, P; Szabó, C; Wagner, F, 2009) |
| "Chronic inflammation is a key factor that accelerates the progression of inflammatory vascular disease." | 1.91 | Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration. ( Lin, XL; Liu, MH; Xiao, LL, 2023) |
| "NaHS treatment decreased hypertension-induced Cx40/Cx43 expressions in T lymphocytes from SHR." | 1.48 | Hydrogen Sulfide Attenuates Hypertensive Inflammation via Regulating Connexin Expression in Spontaneously Hypertensive Rats. ( Li, L; Li, XZ; Ma, KT; Ni, X; Peng, M; Shan, LY; Shen, TW; Si, JQ; Yu, XS; Zhang, L, 2018) |
| "Hydrogen sulfide (H2S) has anti‑inflammatory and neuroprotective properties, particularly during pathological processes." | 1.46 | Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model. ( Han, Z; Huang, J; Jiang, P; Lun, Z; Xiao, B; Xu, J; Xu, Z; Zhou, W, 2017) |
| "Renovascular hypertension was induced by 2-kidney-1-clip, their adult pups were used to evaluate basal blood pressure." | 1.46 | Maternal Renovascular Hypertensive Rats Treatment With Hydrogen Sulfide Increased the Methylation of AT1b Gene in Offspring. ( Duan, X; Feng, X; Guo, Q; Jin, S; Teng, X; Wu, Y; Xiao, L; Xue, H, 2017) |
| "Anemia of inflammation is quite prevalent in hospitalized patients with poor prognosis." | 1.43 | Hydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation. ( Li, C; Miao, L; Shen, Z; Tang, W; Wang, M; Wang, X; Wu, W; Xin, H; Xin, X; Zhu, YZ, 2016) |
| " (but not 1 mg/kg or 6 mg/kg), starting 24 h post-CLP, with dosing repeated every 6 h, improved the survival rate in CLP animals." | 1.43 | Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock. ( Ahmad, A; Druzhyna, N; Szabo, C, 2016) |
| "A major cause of preterm labor in pregnant women is intra-amniotic infection, which is mediated by an inflammatory process." | 1.43 | Hydrogen Sulfide Delays LPS-Induced Preterm Birth in Mice via Anti-Inflammatory Pathways. ( Chemtob, S; Gao, L; Liu, W; Ni, X; Olson, DM; Xu, C; You, X, 2016) |
| "Hydrogen sulfide (H2S) has attracted interest as a gaseous mediator involved in diverse processes in the nervous system, particularly with respect to learning and memory." | 1.43 | The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine. ( El Azhary, NM; Mostafa, DK; Nasra, RA, 2016) |
| "Current COPD therapy involving anticholinergics, β2-adrenoceptor agonists and/or corticosteroids, do not specifically target oxidative stress, nor do they reduce chronic pulmonary inflammation and disease progression in all patients." | 1.43 | The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. ( Bos, IS; Graaf, AC; Halayko, AJ; Han, B; Henning, RH; Krenning, G; Maarsingh, H; Meurs, H; Poppinga, WJ; Schmidt, M; Smit, M; Stienstra, S; van Vliet, B; Vogelaar, P; Zuidhof, AB; Zuo, H, 2016) |
| "Hydrogen sulfide (H2S) functions as a protective gas transmitter in various physiological and pathological processes, but the lack of ideal donors severely hampers the clinical application of H2S." | 1.43 | Controlled release hydrogen sulfide delivery system based on mesoporous silica nanoparticles protects graft endothelium from ischemia-reperfusion injury. ( Guo, C; Liu, Y; Sun, X; Wang, C; Wang, W; Yang, C; Yang, W; Zhang, H, 2016) |
| "Airway inflammation was classified in 77 COPD subjects based on the presence of inflammatory cells in induced sputum." | 1.42 | Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2015) |
| "Hyperglycemia has been reported to activate the nuclear factor-κB (NF-κB) pathway." | 1.42 | Exogenous H2S protects H9c2 cardiac cells against high glucose-induced injury and inflammation by inhibiting the activation of the NF-κB and IL-1β pathways. ( Chen, J; Feng, J; Lin, J; Liu, D; Mo, L; Pan, W; Wu, W; Xu, W; Zheng, D, 2015) |
| "Hydrogen sulfide is a mediator of IRI and can ameliorate tissue injury in many organ systems." | 1.42 | Hydrogen sulfide reduces inflammation following abdominal aortic occlusion in rats. ( Furness, P; Hosgood, SA; Hunter, JP; Nicholson, ML; Patel, M; Sayers, RD, 2015) |
| "Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule with potent anti-inflammatory properties." | 1.42 | Intravital microscopic methods to evaluate anti-inflammatory effects and signaling mechanisms evoked by hydrogen sulfide. ( Korthuis, RJ; Zuidema, MY, 2015) |
| "Hydrogen sulfide also plays an important role in promoting resolution of inflammation, and restoration of normal tissue function." | 1.42 | Anti-inflammatory and cytoprotective properties of hydrogen sulfide. ( Gemici, B; Wallace, JL, 2015) |
| "Hydrogen sulfide (H2S ) has been implicated in the pathogenesis of COPD, but its expression and effects in lung tissue from COPD patients are not clear." | 1.42 | Metabolic changes of H2S in smokers and patients of COPD which might involve in inflammation, oxidative stress and steroid sensitivity. ( Chang, JR; Chen, YH; He, W; Li, MX; Liao, CC; Lin, F; Qi, YF; Sun, Y; Wang, K; Wang, R, 2015) |
| "NaHS treatment in uranium-intoxicated rats activated uranium-inhibited protein expression and nuclear translocation of transcription factor Nrf2, which increased protein expression of downstream target-Nrf2 genes HO-1, NQO-1, GCLC, and TXNRD-1." | 1.42 | Hydrogen sulfide (H2S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways. ( Hu, N; Tang, X; Yuan, Y; Zhao, T; Zheng, J, 2015) |
| "We developed a model of peritoneal fibrosis by intraperitoneally injecting 4." | 1.42 | Hydrogen Sulfide Alleviates Peritoneal Fibrosis via Attenuating Inflammation and TGF-β1 Synthesis. ( Gao, L; Li, L; Lu, Y; Shen, H; Song, K; Wang, Z; Zhu, Y, 2015) |
| "Hydrogen sulfide (H2S) has been proposed as a novel gas-transmittter, which plays multiple physiological and pathological functions in various body systems, including gastrointestinal tract." | 1.40 | Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway. ( Guo, C; Liang, F; Shah Masood, W; Yan, X, 2014) |
| "Inflammation was assessed by measuring serum levels of inflammatory cytokines, including high-sensitivity C-reactive protein, tumour necrosis factor-α, interleukin (IL)-1β and IL-6." | 1.40 | Inhibitory effects of hydrogen sulphide on pulmonary fibrosis in smoking rats via attenuation of oxidative stress and inflammation. ( An, G; Chen, J; Zhou, X, 2014) |
| "Hydrogen sulfide (H2S) is a gaseous signaling molecule that has several important biological functions in the human body." | 1.40 | Design and synthesis of polymeric hydrogen sulfide donors. ( Hasegawa, U; van der Vlies, AJ, 2014) |
| "Hydrogen sulfide (H2S) is an important gaseous signaling agent mediated by many physiological processes and diseases." | 1.40 | Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model. ( Chen, W; Huang, L; Huang, W; Loo, JS; Pei, W; Wang, C; Yan, Q; Yao, C; Zhang, Q; Zhou, Y; Zhu, J, 2014) |
| "Hydrogen sulfide (H2S) is a gaseous mediator synthesized in mammalian tissues by three main enzymes-cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE), and 3-mercaptopyruvate-sulfurtransferase-and its levels increase under inflammatory conditions or sepsis." | 1.40 | Annexin A1 mediates hydrogen sulfide properties in the control of inflammation. ( Brancaleone, V; Cirino, G; Flower, RJ; Mitidieri, E; Perretti, M, 2014) |
| "Hydrogen sulfide is an endogenous inflammatory mediator produced by the activity of cystathionine γ-lyase (CSE) in macrophages." | 1.40 | Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity by downregulation of NF-κB and MAP kinase activity in LPS-activated RAW 264.7 cells. ( Badiei, A; Bhatia, M; Chambers, S; Muniraj, N, 2014) |
| "Hydrogen sulfide is an essential gasotransmitter associated with numerous pathologies." | 1.38 | Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe. ( Dufton, N; Natividad, J; Verdu, EF; Wallace, JL, 2012) |
| "Hydrogen sulfide (H(2)S) is an endogenous gas involved in several biological functions, including modulation of nociception." | 1.35 | Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. ( Cunha, FQ; Cunha, TM; Dal-Secco, D; Ferreira, SH; Guerrero, AT; Lotufo, CM; Neto, AF; Souza, GR; Verri, WA; Vieira, SM, 2008) |
| "Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)." | 1.35 | Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.39) | 18.7374 |
| 1990's | 1 (0.39) | 18.2507 |
| 2000's | 25 (9.69) | 29.6817 |
| 2010's | 169 (65.50) | 24.3611 |
| 2020's | 62 (24.03) | 2.80 |
| Authors | Studies |
|---|---|
| Ravi, R | 1 |
| Kumaraswamy, A | 1 |
| Chauhan, P | 1 |
| Subramaniam Rajesh, B | 1 |
| Liang, T | 1 |
| Zhang, D | 3 |
| Hu, W | 1 |
| Tian, C | 1 |
| Zeng, L | 1 |
| Wu, T | 2 |
| Lei, D | 1 |
| Qiang, T | 1 |
| Yang, X | 2 |
| Sun, X | 6 |
| Glanville, JRW | 1 |
| Jalali, P | 1 |
| Flint, JD | 1 |
| Patel, AA | 1 |
| Maini, AA | 1 |
| Wallace, JL | 12 |
| Hosin, AA | 1 |
| Gilroy, DW | 1 |
| Liu, Z | 2 |
| Chen, L | 2 |
| Gao, X | 1 |
| Zou, R | 1 |
| Meng, Q | 2 |
| Fu, Q | 2 |
| Xie, Y | 2 |
| Miao, Q | 1 |
| Tang, X | 4 |
| Zhang, S | 2 |
| Zhang, H | 8 |
| Schroyen, M | 2 |
| Mendiola, PJ | 1 |
| Naik, JS | 1 |
| Gonzalez Bosc, LV | 1 |
| Gardiner, AS | 1 |
| Birg, A | 1 |
| Kanagy, NL | 1 |
| Scheid, S | 1 |
| Goeller, M | 1 |
| Baar, W | 1 |
| Wollborn, J | 1 |
| Buerkle, H | 1 |
| Schlunck, G | 1 |
| Lagrèze, W | 1 |
| Goebel, U | 1 |
| Ulbrich, F | 1 |
| Lu, X | 1 |
| Zhu, H | 3 |
| Chen, Y | 8 |
| Wu, Y | 6 |
| Zhu, B | 1 |
| Huang, S | 2 |
| Kumar, A | 1 |
| Bhatia, M | 14 |
| Du, J | 4 |
| Wang, P | 3 |
| Gou, Q | 1 |
| Jin, S | 4 |
| Xue, H | 3 |
| Li, D | 1 |
| Tian, D | 3 |
| Sun, J | 2 |
| Zhang, X | 4 |
| Teng, X | 3 |
| Wang, Y | 6 |
| Liao, S | 1 |
| Pan, Z | 1 |
| Jiang, S | 1 |
| Fan, J | 1 |
| Yu, S | 1 |
| Xue, L | 2 |
| Yang, J | 2 |
| Ma, S | 2 |
| Liu, T | 1 |
| Zhang, J | 6 |
| Ding, D | 1 |
| Li, J | 3 |
| Xu, L | 1 |
| Wang, J | 2 |
| Tan, D | 1 |
| Lin, W | 1 |
| Oza, PP | 1 |
| Kashfi, K | 1 |
| Zhu, C | 1 |
| Liu, Q | 3 |
| Li, X | 1 |
| Wei, R | 1 |
| Ge, T | 1 |
| Zheng, X | 1 |
| Li, B | 1 |
| Liu, K | 1 |
| Cui, R | 1 |
| Cui, Y | 2 |
| Hu, G | 2 |
| Nie, Y | 1 |
| Zhou, Y | 4 |
| Wang, S | 6 |
| Liu, X | 6 |
| Liu, Y | 8 |
| Geng, W | 1 |
| Tao, B | 1 |
| He, Y | 1 |
| Li, K | 1 |
| Gao, P | 1 |
| Feng, Q | 1 |
| Zhao, P | 1 |
| Luo, Z | 1 |
| Cai, K | 1 |
| Gupta, K | 1 |
| Mathew, AB | 1 |
| Chakrapani, H | 1 |
| Saini, DK | 1 |
| Cornwell, A | 2 |
| Fedotova, S | 2 |
| Cowan, S | 2 |
| Badiei, A | 5 |
| Xia, Y | 1 |
| Zhang, W | 2 |
| He, K | 1 |
| Bai, L | 1 |
| Miao, Y | 2 |
| Liu, B | 1 |
| Abo-Zaid, OAR | 1 |
| Moawed, FSM | 1 |
| Hassan, HA | 1 |
| Moustafa, EM | 1 |
| Guo, S | 2 |
| Huang, Z | 4 |
| Zhu, J | 2 |
| Yue, T | 1 |
| Wang, X | 8 |
| Pan, Y | 1 |
| Bu, D | 3 |
| Chen, S | 3 |
| Xia, WJ | 1 |
| Liu, KL | 1 |
| Wang, XM | 2 |
| Yang, Y | 3 |
| Meng, T | 1 |
| Qiao, JA | 1 |
| Zhang, N | 1 |
| Sun, YJ | 1 |
| Kang, YM | 1 |
| Yu, XJ | 1 |
| Sharif, AH | 1 |
| Iqbal, M | 1 |
| Manhoosh, B | 1 |
| Gholampoor, N | 1 |
| Ma, D | 1 |
| Marwah, M | 1 |
| Sanchez-Aranguren, L | 1 |
| Lei, H | 1 |
| Hu, Y | 1 |
| Fan, X | 1 |
| Zhang, Y | 4 |
| Xie, L | 1 |
| Huang, J | 2 |
| Cai, Q | 1 |
| Liu, MH | 1 |
| Lin, XL | 1 |
| Xiao, LL | 1 |
| Yuan, S | 1 |
| Zhang, HM | 1 |
| Li, JX | 1 |
| Li, Y | 5 |
| Wang, Q | 2 |
| Kong, GY | 1 |
| Li, AH | 1 |
| Nan, JX | 1 |
| Chen, YQ | 1 |
| Zhang, QG | 1 |
| Inda-Webb, ME | 1 |
| Jimenez, M | 1 |
| Phan, NV | 1 |
| Ahn, J | 1 |
| Steiger, C | 1 |
| Wentworth, A | 1 |
| Riaz, A | 1 |
| Zirtiloglu, T | 1 |
| Wong, K | 1 |
| Ishida, K | 1 |
| Fabian, N | 1 |
| Jenkins, J | 1 |
| Kuosmanen, J | 1 |
| Madani, W | 1 |
| McNally, R | 1 |
| Lai, Y | 1 |
| Hayward, A | 1 |
| Mimee, M | 1 |
| Nadeau, P | 1 |
| Chandrakasan, AP | 1 |
| Traverso, G | 1 |
| Yazicigil, RT | 1 |
| Lu, TK | 1 |
| Ghaiad, HR | 1 |
| A Abd-Elmawla, M | 1 |
| Gad, ES | 1 |
| A Ahmed, K | 1 |
| Abdelmonem, M | 1 |
| Meng, J | 1 |
| Li, L | 11 |
| Geng, Q | 1 |
| Xu, M | 1 |
| Wang, R | 5 |
| Han, X | 1 |
| Shang, Y | 1 |
| Wang, L | 4 |
| Shen, J | 1 |
| Yuan, J | 1 |
| Jain, SK | 4 |
| Justin Margret, J | 1 |
| Lally, M | 1 |
| Dong, B | 1 |
| Sun, Y | 4 |
| Cheng, B | 1 |
| Xue, Y | 1 |
| Li, W | 1 |
| Chi, Q | 2 |
| Wang, D | 2 |
| Hu, X | 4 |
| Li, S | 5 |
| Garattini, EG | 1 |
| Santos, BM | 1 |
| Ferrari, DP | 1 |
| Capel, CP | 1 |
| Francescato, HDC | 1 |
| Coimbra, TM | 4 |
| Leite-Panissi, CRA | 1 |
| Branco, LGS | 1 |
| Nascimento, GC | 1 |
| Wang, YD | 1 |
| Li, JY | 1 |
| Qin, Y | 1 |
| Liao, ZZ | 1 |
| Xiao, XH | 1 |
| Yu, W | 1 |
| Yang, G | 2 |
| Tao, Y | 1 |
| Kong, W | 1 |
| Tang, C | 2 |
| Huang, Y | 3 |
| Jin, H | 2 |
| Ge, X | 1 |
| Fei, A | 1 |
| Gao, C | 1 |
| Pan, S | 3 |
| Wu, Z | 2 |
| Zhang, C | 2 |
| Xu, C | 4 |
| Feng, L | 1 |
| Li, A | 1 |
| Jin, X | 1 |
| Jiao, X | 3 |
| Liu, J | 3 |
| Guo, Y | 3 |
| Han, L | 1 |
| Zhong, K | 1 |
| Li, H | 4 |
| Liao, R | 1 |
| Qiang, Z | 1 |
| Jia, Q | 2 |
| Mehmood, S | 2 |
| Yang, R | 2 |
| Liu, L | 1 |
| Zhou, M | 1 |
| Zhu, R | 1 |
| Zhou, J | 1 |
| Ni, L | 1 |
| Wang, Z | 4 |
| Liu, N | 1 |
| Zhu, F | 1 |
| Shi, T | 1 |
| Deng, Z | 1 |
| Tian, Y | 1 |
| Li, R | 1 |
| Yang, H | 1 |
| Jiang, J | 1 |
| Xu, Y | 2 |
| Donertas Ayaz, B | 1 |
| Zubcevic, J | 1 |
| Sunzini, F | 1 |
| De Stefano, S | 1 |
| Chimenti, MS | 1 |
| Melino, S | 1 |
| Yurinskaya, MM | 1 |
| Krasnov, GS | 1 |
| Kulikova, DA | 1 |
| Zatsepina, OG | 1 |
| Vinokurov, MG | 1 |
| Chuvakova, LN | 1 |
| Rezvykh, AP | 1 |
| Funikov, SY | 1 |
| Morozov, AV | 1 |
| Evgen'ev, MB | 1 |
| Teng, Y | 1 |
| Xuan, S | 1 |
| Jiang, M | 1 |
| Tian, L | 1 |
| Tian, J | 1 |
| Chang, Q | 1 |
| Gross-Amat, O | 1 |
| Guillen, M | 1 |
| Gimeno, JP | 1 |
| Salzet, M | 1 |
| Lebonvallet, N | 1 |
| Misery, L | 1 |
| Auxenfans, C | 1 |
| Nataf, S | 1 |
| Kumar, M | 2 |
| Arora, P | 1 |
| Sandhir, R | 2 |
| Tang, S | 1 |
| Balne, PK | 1 |
| Sinha, NR | 1 |
| Hofmann, AC | 1 |
| Martin, LM | 1 |
| Mohan, RR | 1 |
| Cao, X | 3 |
| Cao, L | 2 |
| Lu, R | 1 |
| Bian, JS | 4 |
| Nie, X | 1 |
| Ling, K | 1 |
| Zhou, W | 2 |
| Chu, J | 1 |
| Xie, F | 1 |
| Wang, W | 3 |
| Parsanathan, R | 1 |
| Achari, AE | 1 |
| Manna, P | 1 |
| Shrestha, D | 1 |
| Bhat, SM | 1 |
| Massey, N | 1 |
| Santana Maldonado, C | 1 |
| Rumbeiha, WK | 1 |
| Charavaryamath, C | 1 |
| Aboulhoda, BE | 1 |
| Rashed, LA | 1 |
| Ahmed, H | 1 |
| Obaya, EMM | 1 |
| Ibrahim, W | 1 |
| Alkafass, MAL | 1 |
| Abd El-Aal, SA | 1 |
| ShamsEldeen, AM | 1 |
| Gyöngyösi, A | 1 |
| Verner, V | 1 |
| Bereczki, I | 1 |
| Kiss-Szikszai, A | 1 |
| Zilinyi, R | 1 |
| Tósaki, Á | 1 |
| Bak, I | 1 |
| Borbás, A | 1 |
| Herczegh, P | 1 |
| Lekli, I | 1 |
| Ni, K | 1 |
| Hua, Y | 1 |
| Yan, L | 1 |
| Jiaqiong, L | 1 |
| Yue, G | 2 |
| Xiaoyong, L | 1 |
| Xuexian, T | 1 |
| Ming, L | 1 |
| Yinglan, L | 1 |
| Xinxue, L | 1 |
| Zena, H | 1 |
| Zhao, X | 1 |
| Ning, L | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enhancement of In-vitro GC Function in Patients With COPD. A Randomised, Double Blind, Placebo Controlled, Parallel-group Study to Investigate the Effect of Theophylline and Fluticasone on Induced Sputum Cells Obtained Form COPD Patients[NCT00241631] | Phase 2 | 49 participants (Actual) | Interventional | 2006-04-30 | Completed | ||
| Pravastatin to Prevent Preeclampsia and Reduce Maternal-Neonatal Mortality and Morbidity in High Risk Preeclampsia Patients[NCT03648970] | Phase 2 | 280 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting | ||
| A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091] | Phase 2 | 20 participants (Anticipated) | Interventional | 2019-08-05 | Recruiting | ||
| Hydrogen Sulfide as Prognostic Factor[NCT01088490] | 50 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Interleukin 8 (IL8) assessed from sputum (NCT00241631)
Timeframe: 10 weeks
| Intervention | ng/mL (Mean) |
|---|---|
| Placebo | 33.3 |
| Steroid | 28.3 |
Supernatant collect, cell pellets count on slides (NCT00241631)
Timeframe: 10 weeks
| Intervention | millions cells/ ml (Mean) |
|---|---|
| Placebo | 5.42 |
| Steroid | 3.89 |
Total eosinophils cells assessed from sputum (NCT00241631)
Timeframe: 10 weeks
| Intervention | millions cells/ml (Mean) |
|---|---|
| Placebo | 0.132 |
| Steroid | 0.053 |
57 reviews available for hydrogen sulfide and Innate Inflammatory Response
| Article | Year |
|---|---|
Role of Hydrogen Sulfide, Substance P and Adhesion Molecules in Acute Pancreatitis.
Topics: Cell Adhesion Molecules; Endothelial Cells; Humans; Hydrogen Sulfide; Inflammation; Integrins; Leuko | 2021 |
Utility of NO and H
Topics: Antiviral Agents; COVID-19; Humans; Hydrogen Sulfide; Inflammation; Nitric Oxide; Pandemics; SARS-Co | 2022 |
Hydrogen sulfide: A new therapeutic target in vascular diseases.
Topics: Atherosclerosis; Humans; Hydrogen Sulfide; Hypertension; Inflammation; Signal Transduction | 2022 |
Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges.
Topics: Humans; Hydrogen Sulfide; Inflammation; Nervous System Diseases; Oxidation-Reduction; Oxidative Stre | 2023 |
Gasotransmitters in non-alcoholic fatty liver disease: just the tip of the iceberg.
Topics: Antioxidants; Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Liver; Non-alcoholic Fatty L | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Gut microbiota and neuroinflammation in pathogenesis of hypertension: A potential role for hydrogen sulfide.
Topics: Animals; Brain; Dysbiosis; Gastrointestinal Microbiome; Humans; Hydrogen Sulfide; Hypertension; Infl | 2020 |
Hydrogen Sulfide as Potential Regulatory
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Gasotransmitters | 2020 |
Therapeutic potential of sulfur-containing natural products in inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents; Biological Products; Gasotransmitters; Humans; Hydrogen Sulfide; | 2020 |
New Therapeutic Approaches Using Hydrogen Sulfide Donors in Inflammation and Immune Response.
Topics: Animals; Humans; Hydrogen Sulfide; Immunity; Inflammation | 2021 |
Hydrogen Sulfide: a Novel Immunoinflammatory Regulator in Rheumatoid Arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Hydrogen Sulfide; Inflammation; Lupus Eryth | 2021 |
Role of Gasotransmitters in Oxidative Stresses, Neuroinflammation, and Neuronal Repair.
Topics: Alzheimer Disease; Carbon Monoxide; Cardiovascular System; Gasotransmitters; Humans; Hydrogen Sulfid | 2017 |
Gaseous Mediators in Gastrointestinal Mucosal Defense and Injury.
Topics: Animals; Carbon Monoxide; Gasotransmitters; Gastric Mucosa; Gastrointestinal Agents; Gastrointestina | 2017 |
[Protective Effect of Hydrogen Sulfide in the Secondary Renal Disease and Renal Transplantation].
Topics: Animals; Antioxidants; Apoptosis; Diabetic Nephropathies; Humans; Hydrogen Sulfide; Inflammation; Ki | 2016 |
[Role Ofhydrogen Sulfide on Inflammatory Immune Disorders in Cardiovascular Diseases].
Topics: Carbon Monoxide; Cardiovascular Diseases; Humans; Hydrogen Sulfide; Immune System Diseases; Inflamma | 2017 |
Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin.
Topics: Animals; Colon; Colorectal Neoplasms; Cysteine; Fusobacterium; Gastrointestinal Microbiome; Humans; | 2019 |
Hydrogen sulfide signaling in the gastrointestinal tract.
Topics: Animals; Bacteria; Gastrointestinal Motility; Gastrointestinal Neoplasms; Gastrointestinal Tract; Hu | 2014 |
Hydrogen sulfide and translational medicine.
Topics: Animals; Apoptosis; Drug Design; Homeostasis; Humans; Hydrogen Sulfide; Inflammation; Signal Transdu | 2013 |
Mitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stress.
Topics: Animals; Carbon Monoxide; Cell Survival; Energy Metabolism; Humans; Hydrogen Sulfide; Inflammation; | 2014 |
Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics.
Topics: Animals; Anti-Inflammatory Agents; Humans; Hydrogen Sulfide; Inflammation; Mucous Membrane; Protecti | 2015 |
Modes of physiologic H2S signaling in the brain and peripheral tissues.
Topics: Animals; Brain; Cardiovascular System; Gasotransmitters; Gastrointestinal Tract; Homeostasis; Humans | 2015 |
Hydrogen sulfide and nitric oxide interactions in inflammation.
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation; Mice; Nitric Oxide; Rats | 2014 |
Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?
Topics: Animals; Carbon Monoxide; Drug Design; Female; Humans; Hydrogen Sulfide; Inflammation; Oxidative Str | 2015 |
[Role of hydrogen sulfide, a gasotransmitter, in colonic pain and inflammation].
Topics: Animals; Colitis; Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Pain; Signal Transductio | 2014 |
Gaseous mediators in resolution of inflammation.
Topics: Anti-Inflammatory Agents; Apoptosis; Carbon Monoxide; Cytoprotection; Gasotransmitters; Homeostasis; | 2015 |
H2S and Inflammation: An Overview.
Topics: Animals; Arthritis; Humans; Hydrogen Sulfide; Inflammation; Pancreatitis; Pulmonary Disease, Chronic | 2015 |
Hydrogen Sulfide and Neuroinflammation.
Topics: Animals; Apoptosis; Humans; Hydrogen Sulfide; Inflammation; Parkinson Disease | 2015 |
Gaseous mediator-based anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Gasotransmitters; Humans; Hydroge | 2015 |
Mitochondrial Quality Control as a Therapeutic Target.
Topics: Carbon Monoxide; Erythropoietin; Estrogens; Free Radical Scavengers; Heme Oxygenase-1; Humans; Hydro | 2016 |
Molecular Dissection of Renal Ischemia-Reperfusion: Oxidative Stress and Cellular Events.
Topics: Acute Kidney Injury; Gene Expression; Heat-Shock Proteins; Humans; Hydrogen Sulfide; Inflammation; M | 2016 |
The role of hydrogen sulfide in burns.
Topics: Animals; Burns; Humans; Hydrogen Sulfide; Inflammation; Sepsis; Wound Healing | 2016 |
Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?
Topics: Animals; Cytoprotection; Garlic; Humans; Hydrogen Sulfide; Inflammation; Sulfonic Acids | 2016 |
H2S-induced thiol-based redox switches: Biochemistry and functional relevance for inflammatory diseases.
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation; Oxidation-Reduction; Sulfhydryl Compounds | 2016 |
Potential applications of hydrogen sulfide-induced suspended animation.
Topics: Animals; Anti-Inflammatory Agents; Energy Metabolism; Hibernation; Humans; Hydrogen Sulfide; Hypoxia | 2009 |
Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation--a tale of three gases!
Topics: Animals; Carbon Monoxide; Cardiovascular System; Humans; Hydrogen Sulfide; Inflammation; Nitric Oxid | 2009 |
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care.
Topics: Animals; Hibernation; Humans; Hydrogen Sulfide; Inflammation; Reperfusion Injury; Shock; Signal Tran | 2009 |
Subtle interplay of endogenous bioactive gases (NO, CO and H(2)S) in inflammation.
Topics: Animals; Carbon Monoxide; Heme Oxygenase-1; Humans; Hydrogen Sulfide; Inflammation; Mitogen-Activate | 2009 |
Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Gastrointestinal Tract; Humans; Hydrogen Sulfide; Inflam | 2010 |
Hydrogen sulfide and substance P in inflammation.
Topics: Air Pollutants; Amino Acid Sequence; Animals; Humans; Hydrogen Sulfide; Inflammation; Inflammation M | 2010 |
Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis.
Topics: Atherosclerosis; Blood Platelets; Calcinosis; Cell Proliferation; Humans; Hydrogen Sulfide; Hyperhom | 2010 |
["Waste gas is not waste": advance in the research of hydrogen sulfide].
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation; Ion Channels; Neovascularization, Physiologic | 2010 |
The role of brain gaseous transmitters in the regulation of the circulatory system.
Topics: Animals; Blood Circulation; Brain; Carbon Monoxide; Hydrogen Sulfide; Inflammation; Nitric Oxide | 2011 |
Hydrogen sulfide-based therapies: focus on H2S releasing NSAIDs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Design | 2011 |
Hydrogen sulfide in inflammation: friend or foe?
Topics: Animals; Anti-Inflammatory Agents; Humans; Hydrogen Sulfide; Inflammation; Inflammation Mediators | 2011 |
Hydrogen sulfide gas has cell growth regulatory role.
Topics: Animals; Cell Proliferation; DNA; Gases; Humans; Hydrogen Sulfide; Inflammation | 2011 |
Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools.
Topics: Animals; Biomarkers; Cytoprotection; Disease Models, Animal; Humans; Hydrogen Sulfide; Inflammation; | 2011 |
Hydrogen sulfide: an endogenous mediator of resolution of inflammation and injury.
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation; Wound Healing | 2012 |
Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising.
Topics: Animals; Anti-Inflammatory Agents; Edema; Humans; Hydrogen Sulfide; Inflammation; Inflammation Media | 2011 |
Therapeutic potential of new hydrogen sulfide-releasing hybrids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Humans; Hydrogen Sulfide; Inf | 2011 |
Therapeutic applications of organosulfur compounds as novel hydrogen sulfide donors and/or mediators.
Topics: Allium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cystathionine beta-Synthase; Cystathionine | 2011 |
Hydrogen sulfide: a gasotransmitter of clinical relevance.
Topics: Animals; Blood Pressure; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytoprotection; Gas | 2012 |
Hydrogen sulfide as a therapeutic target for inflammation.
Topics: Animals; Anti-Inflammatory Agents; Humans; Hydrogen Sulfide; Inflammation; Molecular Targeted Therap | 2012 |
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed.
Topics: Animals; Cardiovascular System; Female; Hibernation; Humans; Hydrogen Sulfide; Immune System; Inflam | 2012 |
H₂S signalling through protein sulfhydration and beyond.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Endoplasmic Reticulum Str | 2012 |
Hydrogen sulphide--a novel mediator of inflammation?
Topics: Animals; Disease Models, Animal; Humans; Hydrogen Sulfide; Inflammation; Vasodilator Agents | 2006 |
Hydrogen sulphide and its therapeutic potential.
Topics: Animals; Cardiovascular Diseases; Humans; Hydrogen Sulfide; Inflammation; Motor Activity; Shock, Hem | 2007 |
Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air?
Topics: Cardiovascular System; Drug Delivery Systems; Endocrine System; Humans; Hydrogen Sulfide; Inflammati | 2008 |
3 trials available for hydrogen sulfide and Innate Inflammatory Response
| Article | Year |
|---|---|
Potent anti-inflammatory effects of an H
Topics: Adolescent; Adult; Dinoprostone; Escherichia coli; Humans; Hydrogen Sulfide; Inflammation; Male; Mid | 2021 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD.
Topics: Adrenal Cortex Hormones; Biomarkers; Bronchodilator Agents; Disease Progression; Forced Expiratory V | 2014 |
199 other studies available for hydrogen sulfide and Innate Inflammatory Response
| Article | Year |
|---|---|
Exogenous administration of hydrogen sulfide alleviates homocysteine induced inflammation in ARPE-19 cells.
Topics: Animals; Cells, Cultured; Cystathionine beta-Synthase; Gene Expression Regulation; Homocysteine; Hyd | 2021 |
A dual lock-and-key two photon fluorescence probe in response to hydrogen peroxide and viscosity: Application in cellular imaging and inflammation therapy.
Topics: Fluorescence; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Peroxide; Hydrogen Sulfide; Inflammatio | 2021 |
Quantitative proteomics reveals tissue-specific toxic mechanisms for acute hydrogen sulfide-induced injury of diverse organs in pig.
Topics: Animals; Hydrogen Sulfide; Inflammation; Inhalation Exposure; Oxidative Stress; Proteomics; Swine | 2022 |
Hydrogen Sulfide Actions in the Vasculature.
Topics: Humans; Hydrogen Sulfide; Inflammation; Neovascularization, Pathologic; Oxidation-Reduction; Signal | 2021 |
Hydrogen Sulfide Reduces Ischemia and Reperfusion Injury in Neuronal Cells in a Dose- and Time-Dependent Manner.
Topics: Animals; Apoptosis; Cytokines; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydro | 2021 |
A novel fluorescent probe for detecting hydrogen sulfide in osteoblasts during lipopolysaccharide-mediated inflammation under periodontitis.
Topics: Animals; Cells, Cultured; Fluorescent Dyes; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Mic | 2021 |
Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.
Topics: Animals; Blood Pressure; Female; Humans; Hydrogen Sulfide; Inflammation; Medulla Oblongata; Pre-Ecla | 2022 |
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis.
Topics: Animals; Antioxidants; Emphysema; Ferroptosis; Humans; Hydrogen Sulfide; Inflammation; Iron; Mice; M | 2022 |
Development of an activatable hydrogen sulfide-specific two-photon fluorescent probe for bioimaging in an air pouch inflammation model.
Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Inflammation; Mice; Photons | 2022 |
Construction of an in vivo NIR fluorescent probe for revealing the correlation between inflammation and mitochondrial hydrogen sulfide and viscosity.
Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Inflammation; Mitochondria; Optical | 2022 |
Hydrogen sulfide protects from acute kidney injury via attenuating inflammation activated by necroptosis in dogs.
Topics: Acute Kidney Injury; Adenosine Diphosphate Ribose; Animals; Cisplatin; Dog Diseases; Dogs; Hydrogen | 2022 |
Nitric Oxide Scavenging and Hydrogen Sulfide Production Synergistically Treat Rheumatoid Arthritis.
Topics: Animals; Arthritis, Rheumatoid; Hydrogen Sulfide; Inflammation; NF-kappa B; Nitric Oxide; Rats; Sulf | 2023 |
H
Topics: Cellular Senescence; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Inflammation; NF-kappa B; | 2023 |
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
Topics: Cystathionine gamma-Lyase; Glucose Transport Proteins, Facilitative; Humans; Hydrogen Sulfide; Infla | 2022 |
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
Topics: Cystathionine gamma-Lyase; Glucose Transport Proteins, Facilitative; Humans; Hydrogen Sulfide; Infla | 2022 |
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
Topics: Cystathionine gamma-Lyase; Glucose Transport Proteins, Facilitative; Humans; Hydrogen Sulfide; Infla | 2022 |
Cystathionine γ-lyase and hydrogen sulfide modulates glucose transporter Glut1 expression via NF-κB and PI3k/Akt in macrophages during inflammation.
Topics: Cystathionine gamma-Lyase; Glucose Transport Proteins, Facilitative; Humans; Hydrogen Sulfide; Infla | 2022 |
Hydrogen sulfide alleviates lipopolysaccharide-induced myocardial injury through TLR4-NLRP3 pathway.
Topics: Animals; Cardiomyopathies; Heart Injuries; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Male | 2023 |
Hydrogen sulfide attenuates lung injury instigated by Bisphenol-A via suppressing inflammation and oxidative stress.
Topics: Animals; Female; Hydrogen Sulfide; Inflammation; Lung Injury; Oxidative Stress; Rats | 2022 |
CBS-H
Topics: Animals; Colitis; Cyclooxygenase 2; Humans; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Mic | 2023 |
Hypothalamic Paraventricular Nucleus Hydrogen Sulfide Exerts Antihypertensive Effects in Spontaneously Hypertensive Rats via the Nrf2 Pathway.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Hydrogen Sulfide; Hyperten | 2023 |
A turn-on fluorescent nanosensor for H
Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Inflammation; Mice; Microscopy, Flu | 2023 |
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Topics: Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Inflammation; Interleukin-6; Macrophages; NF-ka | 2023 |
Sub-1.4 cm
Topics: Administration, Oral; Animals; Bacteria; Biomarkers; Biosensing Techniques; Body Size; Capsules; Dis | 2023 |
Modulating miR-146a Expression by Hydrogen Sulfide Ameliorates Motor Dysfunction and Axonal Demyelination in Cuprizone-Induced Multiple Sclerosis.
Topics: Animals; Cuprizone; Hydrogen Sulfide; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Multi | 2023 |
Hydrogen sulfide ameliorates senescence in vascular endothelial cells through ameliorating inflammation and activating PPARδ/SGLT2/STAT3 signaling pathway.
Topics: Endothelial Cells; Humans; Hydrogen Sulfide; Inflammation; PPAR delta; Sodium-Glucose Transporter 2; | 2023 |
Hydrogen sulfide releasing poly(γ-glutamic acid) biocomposite hydrogel with monitoring, antioxidant, and antibacterial properties for diabetic wound healing.
Topics: Anthocyanins; Anti-Bacterial Agents; Antioxidants; Diabetes Mellitus; Glutamic Acid; Humans; Hydroge | 2023 |
Positive association of acetylcholinesterase (AChE) with the neutrophil-to-lymphocyte ratio and HbA1c, and a negative association with hydrogen sulfide (H
Topics: Acetylcholinesterase; Alzheimer Disease; Black or African American; Glucose; Glycated Hemoglobin; Hu | 2023 |
Activating transcription factor (ATF) 6 upregulates cystathionine β synthetase (CBS) expression and hydrogen sulfide (H
Topics: Activating Transcription Factor 6; Animals; Cystathionine; Cystathionine beta-Synthase; Fatty Liver; | 2023 |
Hydrogen Sulfide Gas Exposure Induces Necroptosis and Promotes Inflammation through the MAPK/NF-
Topics: Animals; Chickens; Humans; Hydrogen Sulfide; Inflammation; Necroptosis; NF-kappa B; Spleen | 2019 |
Propargylglycine decreases neuro-immune interaction inducing pain response in temporomandibular joint inflammation model.
Topics: Alkynes; Animals; Cystathionine gamma-Lyase; Enzyme Inhibitors; Glycine; Hydrogen Sulfide; Hyperalge | 2019 |
Exogenous Hydrogen Sulfide Alleviates-Induced Intracellular Inflammation in HepG2 Cells.
Topics: Cytokines; Hep G2 Cells; Hepatocytes; Humans; Hydrogen Sulfide; Inflammasomes; Inflammation; NLR Fam | 2020 |
Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation.
Topics: Animals; Cells, Cultured; Cysteine; Cytokines; Down-Regulation; Endothelial Cells; Endothelium, Vasc | 2019 |
Hydrogen sulfide treatment alleviated ventilator-induced lung injury through regulation of autophagy and endoplasmic reticulum stress.
Topics: Animals; Autophagy; Endoplasmic Reticulum Stress; Hydrogen Sulfide; Inflammation; Male; Oxidative St | 2019 |
H
Topics: Animals; Apoptosis; Cattle; Cell Line; Epithelial Cells; Female; Hydrogen Sulfide; Inflammation; Mam | 2020 |
Release of endogenous hydrogen sulfide in enteric nerve cells suppresses intestinal motility during severe acute pancreatitis.
Topics: Animals; Cell Movement; Chromones; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytokines | 2020 |
Hydrogen sulfide mitigates myocardial inflammation by inhibiting nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome activation in diabetic rats.
Topics: Animals; Carrier Proteins; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Inflammasomes; Inflamm | 2020 |
Hydrogen sulfide protects against particle-induced inflammatory response and osteolysis via SIRT1 pathway in prosthesis loosening.
Topics: Animals; Blotting, Western; Cell Survival; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody T | 2020 |
H
Topics: Anti-Inflammatory Agents; Cell Line; Cytokines; Humans; Hydrogen Sulfide; Inflammation; Lipopolysacc | 2020 |
Expression of H
Topics: Biomarkers; Blood Glucose; Diabetes, Gestational; Female; Fetal Blood; Glucose Tolerance Test; Human | 2020 |
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Topics: Animals; Collagen; Cytokines; Diabetes Mellitus, Experimental; Diaphragm; Fibrosis; Hydrogen Sulfide | 2020 |
Molecular Mapping of Hydrogen Sulfide Targets in Normal Human Keratinocytes.
Topics: Apoptosis; Cullin Proteins; Humans; Hydrogen Sulfide; Inflammasomes; Inflammation; Keratinocytes; NA | 2020 |
Hydrogen Sulfide Reverses LPS-Induced Behavioral Deficits by Suppressing Microglial Activation and Promoting M2 Polarization.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Brain; Cell Differentiation; Hydr | 2021 |
Proteomics analysis of lung reveals inflammation and cell death induced by atmospheric H
Topics: Animals; Cell Death; Hydrogen Sulfide; Inflammation; Lung; Proteomics; Swine | 2020 |
Characterization of hydrogen sulfide toxicity to human corneal stromal fibroblasts.
Topics: Cells, Cultured; Corneal Stroma; Cytotoxins; Fibroblasts; Gene Expression Regulation; Humans; Hydrog | 2020 |
H
Topics: Angioplasty; Animals; Antioxidants; Cell Movement; Cell Proliferation; Coronary Restenosis; Hydrogen | 2021 |
l-Cysteine and Vitamin D Co-Supplementation Alleviates Markers of Musculoskeletal Disorders in Vitamin D-Deficient High-Fat Diet-Fed Mice.
Topics: Animals; Biomarkers; Cysteine; Cytokines; Diet, High-Fat; Dietary Supplements; Feeding Behavior; Gen | 2020 |
Pre-exposure to hydrogen sulfide modulates the innate inflammatory response to organic dust.
Topics: Animals; Disease Models, Animal; Dust; Humans; Hydrogen Sulfide; Inflammation; Mice | 2021 |
Hydrogen sulfide and mesenchymal stem cells-extracted microvesicles attenuate LPS-induced Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cell-Derived Microparticles; Female; Hydrogen Sulfide; Inflammation; Lip | 2021 |
Basic Pharmacological Characterization of EV-34, a New H
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenas | 2021 |
Hydrogen sulfide exacerbated periodontal inflammation and induced autophagy in experimental periodontitis.
Topics: Animals; Anti-Inflammatory Agents; Autophagy; Beclin-1; Cells, Cultured; Humans; Hydrogen Sulfide; I | 2021 |
Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Topics: Acute Kidney Injury; Animals; Apoptosis; Atorvastatin; Contrast Media; Cystathionine beta-Synthase; | 2020 |
An Activatable Near-Infrared Fluorescence Hydrogen Sulfide (H
Topics: Animals; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Inflammation; Zebrafish | 2021 |
Hydrogen sulfide alleviates the anxiety-like and depressive-like behaviors of type 1 diabetic mice via inhibiting inflammation and ferroptosis.
Topics: Animals; Anti-Inflammatory Agents; Anxiety; Depression; Diabetes Mellitus, Type 1; Ferroptosis; Gaso | 2021 |
Hydrogen Sulfide and its Interaction with Other Players in Inflammation.
Topics: Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Reactive Oxygen Species; Signal Transducti | 2021 |
Hydrogen Sulfide Improves Functional Recovery in Rat Traumatic Spinal Cord Injury Model by Inducing Nuclear Translocation of NF-E2-Related Factor 2.
Topics: Animals; Apoptosis; Disease Models, Animal; Endoplasmic Reticulum Stress; Hydrogen Sulfide; Inflamma | 2021 |
Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn.
Topics: Analysis of Variance; Animals; Biomarkers; Blotting, Western; Burns; Cystathionine gamma-Lyase; Cyto | 2017 |
Reduction of leukocyte-derived H
Topics: Adult; Aged; Blood Glucose; Cholesterol, HDL; Cystathionine gamma-Lyase; Down-Regulation; Female; Gl | 2017 |
Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model.
Topics: Animals; Blood-Brain Barrier; Cystathionine beta-Synthase; Disease Models, Animal; Female; Hydrogen | 2017 |
Reduction of hydrogen sulfide synthesis enzymes cystathionine-β-synthase and cystathionine-γ-lyase in the colon of patients with Hirschsprungs disease.
Topics: Blotting, Western; Colon; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Enterocolitis; Fem | 2018 |
Hydrogen sulfide improves diabetic wound healing in ob/ob mice via attenuating inflammation.
Topics: Adult; Animals; Case-Control Studies; Humans; Hydrogen Sulfide; Inflammation; Male; Mice; Mice, Inbr | 2017 |
The Role of Exogenous Hydrogen Sulfide in Free Fatty Acids Induced Inflammation in Macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Line; Cell Survival; Fa | 2017 |
Maternal Renovascular Hypertensive Rats Treatment With Hydrogen Sulfide Increased the Methylation of AT1b Gene in Offspring.
Topics: Animals; Blood Pressure; DNA Methylation; Female; Fetal Development; Hydrogen Sulfide; Hypertension, | 2017 |
Hydrogen Sulfide Attenuates Hypertensive Inflammation via Regulating Connexin Expression in Spontaneously Hypertensive Rats.
Topics: Animals; Basilar Artery; Blood Pressure; Connexins; Hydrogen Sulfide; Hypertension; Inflammation; Ki | 2018 |
Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress.
Topics: Acute Kidney Injury; Animals; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Male; Mice; Oxida | 2018 |
Exogenous hydrogen sulfide ameliorates high glucose-induced myocardial injury & inflammation via the CIRP-MAPK signaling pathway in H9c2 cardiac cells.
Topics: Animals; Apoptosis; Cells, Cultured; Cold Shock Proteins and Peptides; Glucose; Hydrogen Sulfide; In | 2018 |
Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cathepsins; Cell Line; Ce | 2018 |
The effects of atmospheric hydrogen sulfide on peripheral blood lymphocytes of chickens: Perspectives on inflammation, oxidative stress and energy metabolism.
Topics: Air Pollutants; Air Pollution; Animals; Chickens; Energy Metabolism; Hydrogen Sulfide; Inflammation; | 2018 |
Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway.
Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Forkhead Box Protein O1; Hear | 2018 |
Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism.
Topics: Acetylation; Animals; Bone Remodeling; Chromatin; Core Binding Factor Alpha 1 Subunit; Cystathionine | 2018 |
LPS-induced Apoptosis is Partially Mediated by Hydrogen Sulphide in RAW 264.7 Murine Macrophages.
Topics: Alkynes; Animals; Antibodies, Blocking; Apoptosis; bcl-2-Associated X Protein; Cystathionine gamma-L | 2019 |
Memantine prodrug as a new agent for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autophagy; Cell Line; Humans; Hydrogen Sulfide; I | 2019 |
Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Bronchoalveolar Lavage Fluid; Cystathionine gamma-Lya | 2019 |
An H
Topics: Carbon Monoxide; Fluorescence; Hydrogen Sulfide; Inflammation; Magnetic Resonance Spectroscopy; Mass | 2019 |
Hydrogen sulfide suppresses homocysteine-induced glial activation and inflammatory response.
Topics: Animals; Homocysteine; Hydrogen Sulfide; Inflammation; Male; Neuroglia; Rats; Rats, Sprague-Dawley | 2019 |
Hydrogen sulfide impacts on inflammation-induced adipocyte dysfunction.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Alkynes; Animals; Cell Differentiation; Gene Expression; Gly | 2019 |
Hydrogen Sulfide Attenuates High Glucose-Induced Human Retinal Pigment Epithelial Cell Inflammation by Inhibiting ROS Formation and NLRP3 Inflammasome Activation.
Topics: Cell Line; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Glucose; Humans; Hydr | 2019 |
Hydrogen sulfide inhibits inflammation and improves chronic renal failure through NF-κB signaling pathway.
Topics: Animals; Hydrogen Sulfide; Inflammation; Kidney Failure, Chronic; NF-kappa B; Rats; Signal Transduct | 2021 |
Biphasic regulation of hydrogen sulfide in inflammation.
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation | 2013 |
Estrogens increase cystathionine-γ-lyase expression and decrease inflammation and oxidative stress in the myocardium of ovariectomized rats.
Topics: Animals; Antioxidants; Cystathionine gamma-Lyase; Cytokines; Estradiol; Female; Hydrogen Sulfide; In | 2013 |
Inhibition of ROS-activated p38MAPK pathway is involved in the protective effect of H2S against chemical hypoxia-induced inflammation in PC12 cells.
Topics: Animals; Cobalt; Hydrogen Sulfide; Hypoxia; Inflammation; Interleukin-6; Nitric Oxide; Nitric Oxide | 2013 |
Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Carbon Dioxide; Cell Line; Disease Models, Anima | 2013 |
Preconditioning with soluble guanylate cyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice.
Topics: Animals; Benzoates; Biphenyl Compounds; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal | 2013 |
Exogenous hydrogen sulfide prevents kidney damage following unilateral ureteral obstruction.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibrosis; Gasotransmitters; Hydrogen Sulfide; | 2014 |
Dysregulation of cystathionine γ-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage.
Topics: Animals; Cell Adhesion; Cell Line; Cystathionine gamma-Lyase; Cysteine; Gene Expression Regulation; | 2013 |
Inflammatory acidic pH enhances hydrogen sulfide-induced transient receptor potential ankyrin 1 activation in RIN-14B cells.
Topics: Animals; Cell Line; Hydrogen Sulfide; Hydrogen-Ion Concentration; Inflammation; Pain; Rats; Reactive | 2013 |
Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain; Gasotransmitters; Homocysteine; Hydrogen Sul | 2013 |
Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats.
Topics: Animals; Choline Deficiency; Cytochrome P-450 CYP2E1; Disease Models, Animal; Disease Progression; F | 2014 |
Could hydrogen sulfide be the next blockbuster treatment for inflammatory disease?
Topics: Animals; Anti-Inflammatory Agents; Humans; Hydrogen Sulfide; Inflammation; Mice | 2013 |
Hydrogen sulfide as a potential biomarker of asthma.
Topics: Asthma; Biomarkers; Humans; Hydrogen Sulfide; Inflammation; Lung; Phenotype; Sputum | 2014 |
Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway.
Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Line; Cell Nucleus; Cytoprotection; Epithelial Cells | 2014 |
Upregulation of cystathionine-β-synthetase expression contributes to inflammatory pain in rat temporomandibular joint.
Topics: Action Potentials; Animals; Cystathionine beta-Synthase; Electric Stimulation; Enzyme Inhibitors; Fr | 2014 |
Hydrogen sulfide suppresses oxidized low-density lipoprotein (ox-LDL)-stimulated monocyte chemoattractant protein 1 generation from macrophages via the nuclear factor κB (NF-κB) pathway.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line; Cell Nucleus; Chemokine CCL2; Gasotransmitters; | 2014 |
CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation.
Topics: AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cells, C | 2014 |
Inhibitory effects of hydrogen sulphide on pulmonary fibrosis in smoking rats via attenuation of oxidative stress and inflammation.
Topics: Air Pollutants; Animals; Blotting, Western; Cells, Cultured; Electrophoretic Mobility Shift Assay; E | 2014 |
Redox regulation of endothelial cell fate.
Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Cell Movement; Cell Transdifferentiation; C | 2014 |
Hydrogen sulfide upregulates glutamate-cysteine ligase catalytic subunit, glutamate-cysteine ligase modifier subunit, and glutathione and inhibits interleukin-1β secretion in monocytes exposed to high glucose levels.
Topics: Atherosclerosis; Catalytic Domain; Cell Survival; Enzyme-Linked Immunosorbent Assay; Glucose; Glutam | 2014 |
Hydrogen sulfide attenuates the recruitment of CD11b⁺Gr-1⁺ myeloid cells and regulates Bax/Bcl-2 signaling in myocardial ischemia injury.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein; CD11b Antigen; Cell Moveme | 2014 |
Interactions of hydrogen sulfide with myeloperoxidase.
Topics: Animals; Circular Dichroism; Electron Spin Resonance Spectroscopy; Humans; Hydrogen Sulfide; Inflamm | 2015 |
Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes.
Topics: Aged; Aged, 80 and over; Biomarkers; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dinoprosto | 2014 |
A colorimetric and ratiometric fluorescent probe for the imaging of endogenous hydrogen sulphide in living cells and sulphide determination in mouse hippocampus.
Topics: Animals; Azides; Brain; Cattle; Colorimetry; Cystathionine beta-Synthase; Fluorescent Dyes; Gene Exp | 2014 |
Design and synthesis of polymeric hydrogen sulfide donors.
Topics: Animals; Blood Proteins; Cells, Cultured; Drug Design; Humans; Hydrogen Sulfide; Inflammation; Lipop | 2014 |
H₂S protecting against lung injury following limb ischemia-reperfusion by alleviating inflammation and water transport abnormality in rats.
Topics: Acute Lung Injury; Animals; Aquaporins; Drug Evaluation, Preclinical; Edema; Hydrogen Sulfide; Infla | 2014 |
Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cystathionine beta-Synthase; Cystathioni | 2015 |
Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model.
Topics: Animals; Carbocyanines; Coumarins; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hyd | 2014 |
Annexin A1 mediates hydrogen sulfide properties in the control of inflammation.
Topics: Animals; Annexin A1; Aorta; Bone Marrow Cells; Cell Adhesion; Cell Movement; Cyclooxygenase 2; Cysta | 2014 |
Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model.
Topics: Animals; Basement Membrane; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Nephropath | 2014 |
Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma.
Topics: Adult; Asthma; Biomarkers; Exhalation; Female; Forced Expiratory Volume; Humans; Hydrogen Sulfide; I | 2014 |
Signaling of hydrogen sulfide and polysulfides.
Topics: Animals; Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Reperfusion Injury; Signal Transd | 2015 |
Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity by downregulation of NF-κB and MAP kinase activity in LPS-activated RAW 264.7 cells.
Topics: Animals; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymologic; Gene Silencing; Hydroge | 2014 |
Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD.
Topics: Aged; Area Under Curve; Biomarkers; Breath Tests; Eosinophilia; Eosinophils; Exhalation; Female; For | 2015 |
Exogenous H2S protects H9c2 cardiac cells against high glucose-induced injury and inflammation by inhibiting the activation of the NF-κB and IL-1β pathways.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytokines; Enzyme Activation; Hydrogen Sulfide; Hyperg | 2015 |
Hydrogen sulfide reduces inflammation following abdominal aortic occlusion in rats.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Constriction; Disease Mode | 2015 |
H2S2014 in Kyoto: the 3rd International Conference on H2S in Biology and Medicine.
Topics: Animals; Biochemistry; Cell Physiological Phenomena; Humans; Hydrogen Sulfide; Inflammation; Japan; | 2015 |
Inflammation's stop signals.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents; Fatty Acids, Unsaturated; Humans; Hydrogen Sulfide; I | 2015 |
Intravital microscopic methods to evaluate anti-inflammatory effects and signaling mechanisms evoked by hydrogen sulfide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Adhesion; Cell Moveme | 2015 |
Attenuation of inflammatory responses by hydrogen sulfide (H₂S) in ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Central Nervous System; Cyt | 2015 |
Anti-inflammatory and cytoprotective properties of hydrogen sulfide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cystathionine beta-Syntha | 2015 |
CD47-dependent regulation of H₂S biosynthesis and signaling in T cells.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Asthma | 2015 |
Hydrogen sulfide attenuates IL-1β-induced inflammatory signaling and dysfunction of osteoarthritic chondrocytes.
Topics: Chondrocytes; Cyclooxygenase 2; Dinoprostone; Female; Humans; Hydrogen Sulfide; Inflammation; Interl | 2015 |
Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hepatobiliary Elimination; Hydrogen Sulfide; Infla | 2015 |
[Effect of intestinal resection on hydrogen sulfide biosynthesis and the damage of Cajal interstitial cells].
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Hydrogen Sulfide; Inflammation; Intersti | 2015 |
Hydrogen Sulfide Ameliorates Early Brain Injury Following Subarachnoid Hemorrhage in Rats.
Topics: Animals; Apoptosis; Behavior, Animal; Brain; Brain Injuries; Caspases; Cerebral Arteries; Cystathion | 2016 |
Hydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation.
Topics: Acetylation; Animals; Cells, Cultured; Hepcidins; Hydrogen Sulfide; Inflammation; Interleukin-6; Mal | 2016 |
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expr | 2015 |
Metabolic changes of H2S in smokers and patients of COPD which might involve in inflammation, oxidative stress and steroid sensitivity.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cystathionine beta-Syn | 2015 |
Hydrogen sulfide (H2S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways.
Topics: Animals; Hydrogen Sulfide; Inflammation; Kidney; Male; NF-E2-Related Factor 2; NF-kappa B; Oxidative | 2015 |
Hydrogen Sulfide Alleviates Peritoneal Fibrosis via Attenuating Inflammation and TGF-β1 Synthesis.
Topics: Actins; Animals; Chemokine CCL2; Collagen Type III; Dialysis; Fibronectins; Hydrogen Sulfide; Inflam | 2015 |
Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.
Topics: Animals; Hydrogen Sulfide; Inflammation; Interleukin-5; Interleukin-6; Ligation; Male; Neutrophil In | 2016 |
Cystathionine-γ-lyase gene silencing with siRNA in monocytes/ macrophages attenuates inflammation in cecal ligation and puncture-induced sepsis in the mouse.
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Gene Silencing; Humans; Hydrogen Sulfide | 2016 |
Hydrogen Sulfide Delays LPS-Induced Preterm Birth in Mice via Anti-Inflammatory Pathways.
Topics: Animals; Cytokines; Female; Hydrogen Sulfide; Inflammation; Inflammation Mediators; Lipopolysacchari | 2016 |
The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine.
Topics: Allyl Compounds; Animals; Arginine; Cognitive Dysfunction; Hydrogen Sulfide; Inflammation; Inflammat | 2016 |
MicroRNA-186 promotes macrophage lipid accumulation and secretion of pro-inflammatory cytokines by targeting cystathionine γ-lyase in THP-1 macrophages.
Topics: 3' Untranslated Regions; Alleles; Cystathionine gamma-Lyase; Cytokines; HEK293 Cells; Humans; Hydrog | 2016 |
Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China.
Topics: Aged; Air Pollutants; Air Pollution; Beijing; Biomarkers; Dyspnea; Environmental Exposure; Female; H | 2016 |
The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line, Transformed; Chromans; Co | 2016 |
A H 2 S Donor GYY4137 Exacerbates Cisplatin-Induced Nephrotoxicity in Mice.
Topics: Animals; Apoptosis; Cisplatin; Hydrogen Sulfide; Inflammation; Kidney; Kidney Tubules; Male; Mice; M | 2016 |
Controlled release hydrogen sulfide delivery system based on mesoporous silica nanoparticles protects graft endothelium from ischemia-reperfusion injury.
Topics: Allyl Compounds; Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Delayed-Action Prepar | 2016 |
Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention.
Topics: Animals; Hydrogen Sulfide; Hypoglycemic Agents; Inflammation; Inflammation Mediators; Lipopolysaccha | 2016 |
HNO suppresses LPS-induced inflammation in BV-2 microglial cells via inhibition of NF-κB and p38 MAPK pathways.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; HEK293 Cells; Humans; Hydrogen Sulfi | 2016 |
S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway.
Topics: Anemia; Animals; Cysteine; Disease Models, Animal; Hepcidins; Hydrogen Sulfide; Inflammation; Interl | 2016 |
Exogenous hydrogen sulfide protects against high glucose‑induced inflammation and cytotoxicity in H9c2 cardiac cells.
Topics: Apoptosis; Caspase 3; Cell Line; Cell Survival; Cytokines; Glucose; Humans; Hydrogen Sulfide; Inflam | 2016 |
Effects of CCK-8 and Cystathionine γ-Lyase/Hydrogen Sulfide System on Acute Lung Injury in Rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cystathionine gamma-Lyase; Humans; Hydrogen Su | 2017 |
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Topics: Anemia; Animals; Cell Line; Cells, Cultured; Fluorescent Antibody Technique; Hepcidins; Humans; Hydr | 2017 |
Production of endogenous hydrogen sulfide in human gingival tissue.
Topics: Adolescent; Adult; Aged; Chronic Periodontitis; Cystathionine beta-Synthase; Cystathionine gamma-Lya | 2017 |
Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells.
Topics: Animals; Apoptosis; Cardiotoxicity; Cell Line; Cytoprotection; Gene Silencing; Glucose; Hydrogen Sul | 2016 |
H2S Attenuates LPS-Induced Acute Lung Injury by Reducing Oxidative/Nitrative Stress and Inflammation.
Topics: Acute Lung Injury; Animals; Antioxidants; Endotoxemia; Hydrogen Peroxide; Hydrogen Sulfide; Inflamma | 2016 |
Effect of Physical Exercise on the Febrigenic Signaling is Modulated by Preoptic Hydrogen Sulfide Production.
Topics: Animals; Body Temperature Regulation; Corticosterone; Cystathionine beta-Synthase; Cystathionine gam | 2017 |
Endogenous hydrogen sulfide contributes to uterine quiescence during pregnancy.
Topics: Air Pollutants; Cells, Cultured; Cystathionine gamma-Lyase; Cytokines; Extracellular Signal-Regulate | 2017 |
Cardioprotection by hydrogen sulfide: suspended animation, inflammation, and apoptosis.
Topics: Animals; Apoptosis; Gene Deletion; Humans; Hydrogen Sulfide; Hypoxia; Inflammation; Models, Biologic | 2009 |
Dual role of hydrogen sulfide in mechanical inflammatory hypernociception.
Topics: Analgesics; Animals; Cell Movement; Hydrogen Sulfide; Inflammation; KATP Channels; Male; Mice; Mice, | 2008 |
[Hypotensive effects of hydrogen sulfide via attenuating vascular inflammation in spontaneously hypertensive rats].
Topics: Animals; Blood Pressure; Hydrogen Sulfide; Hypertension; I-kappa B Kinase; Inflammation; Intercellul | 2008 |
Hydrogen sulphide is pro-inflammatory in haemorrhagic shock.
Topics: Alkynes; Animals; Blood Pressure; Glycine; Heart Rate; Hydrogen Sulfide; Inflammation; Interleukin-1 | 2008 |
Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cystathionine gamma-Lyase; Disease Models, Animal; En | 2009 |
Physiology: Emissions control.
Topics: Animals; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Hypertension; Inflammation; Mice; Nitr | 2009 |
Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cystathionine gamma-Lyase; Hydrogen Sulfide; I | 2009 |
Hydrogen sulfide: the third gasotransmitter in biology and medicine.
Topics: Animals; Antioxidants; Humans; Hydrogen Sulfide; Hypoxia; Inflammation; Ischemia; Neurodegenerative | 2010 |
NF-kappaB independent activation of a series of proinflammatory genes by hydrogen sulfide.
Topics: Animals; Enzyme Activation; Fibroblasts; Humans; Hydrogen Sulfide; Inflammation; Inflammation Mediat | 2009 |
Low levels of hydrogen sulfide in the blood of diabetes patients and streptozotocin-treated rats causes vascular inflammation?
Topics: Animals; Blood Vessels; Diabetes Mellitus, Type 2; Glucose; Humans; Hydrogen Sulfide; Inflammation; | 2010 |
Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis.
Topics: Animals; Collagen; Cystathionine beta-Synthase; Down-Regulation; Homocysteine; Hydrogen Sulfide; Hyp | 2010 |
Hydrogen sulfide attenuates lipopolysaccharide-induced cognitive impairment: a pro-inflammatory pathway in rats.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Hydrogen Sulfide; Inflammation; Lipopolysaccharides | 2010 |
Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage.
Topics: Alkynes; Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Enzyme Inhibitors; Glyci | 2011 |
Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury.
Topics: Administration, Inhalation; Animals; Hydrogen Sulfide; Inflammation; Male; Metabolism; Monitoring, P | 2010 |
Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2.
Topics: Animals; Cyclooxygenase Inhibitors; Cyproheptadine; Cystathionine beta-Synthase; Cystathionine gamma | 2010 |
Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels.
Topics: Animals; Apamin; Cells, Cultured; Electrophysiological Phenomena; Endothelium, Vascular; Humans; Hyd | 2010 |
Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock.
Topics: Animals; Chemokine CCL2; Chemokine CCL8; Chemokines; Electrophoretic Mobility Shift Assay; Heme Oxyg | 2011 |
Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation.
Topics: Animals; Cells, Cultured; Chemokine CCL2; Chemokine CXCL2; Cystathionine beta-Synthase; Cystathionin | 2011 |
Hydrogen sulfide-mediated cardioprotection: mechanisms and therapeutic potential.
Topics: Animals; Atherosclerosis; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Humans | 2011 |
Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung.
Topics: Acetylcholine; Alkynes; Animals; Cystathionine gamma-Lyase; Dose-Response Relationship, Drug; Enzyme | 2011 |
Hydrogen sulfide: from physiology to pharmacology.
Topics: Animals; Anti-Inflammatory Agents; Cysteine; Disease Models, Animal; Drug Design; Humans; Hydrogen S | 2011 |
S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.
Topics: Animals; Cell Line; Cysteine; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Myocytes, Cardiac | 2011 |
Role of endogenous hydrogen sulfide on renal damage induced by adriamycin injection.
Topics: Alkynes; Animals; Antibiotics, Antineoplastic; Doxorubicin; Glutathione; Glycine; Hydrogen Sulfide; | 2011 |
COXIBs, CINODs and H₂S-releasing NSAIDs: current perspectives in the development of safer non steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Gastrointestinal Hemorrhage; G | 2011 |
Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling.
Topics: Animals; Capsaicin; Cell Nucleus; Chemokines; Cytokines; Extracellular Signal-Regulated MAP Kinases; | 2011 |
Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Carbon Tetrachloride; Cy | 2011 |
Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma.
Topics: Administration, Inhalation; Animals; Body Temperature; Cytokines; Hydrogen Sulfide; Hypoxia; Inflamm | 2012 |
Follow-through after breakthrough.
Topics: Animals; Humans; Hydrogen Sulfide; Inflammation; Inflammation Mediators; Signal Transduction | 2011 |
Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Endotoxins; Hydrogen Sulfide; Inflamm | 2012 |
Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ceruletide; Cysteine; Cyt | 2012 |
Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.
Topics: Alkynes; Animals; Anti-Bacterial Agents; Cystathionine gamma-Lyase; Female; Gentamicins; Glycine; Hy | 2012 |
Protective role of methionine sulfoxide reductase A against ischemia/reperfusion injury in mouse kidney and its involvement in the regulation of trans-sulfuration pathway.
Topics: Animals; Antigens, Ly; Disease Models, Animal; Enzyme Activation; Gene Deletion; Gene Expression Reg | 2013 |
Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe.
Topics: Animals; Chemotaxis; Cystathionine beta-Synthase; Fluorescent Dyes; Humans; Hydrogen Sulfide; Inflam | 2012 |
The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster.
Topics: Airway Remodeling; Animals; Biomarkers; Collagen; Cricetinae; Cystathionine beta-Synthase; Extracell | 2012 |
Fatal and non-fatal cases of lime sulfide exposure and pathogenetic mechanisms underlying pancreatic injury: Case reports with an animal experiment.
Topics: Adult; Aged; Air Pollutants; Amylases; Animals; Calcium Compounds; Esophagus; Female; Forensic Patho | 2012 |
Hydrogen sulfide attenuates spatial memory impairment and hippocampal neuroinflammation in β-amyloid rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Hydrogen Sul | 2012 |
Altered response to hydrogen sulphide during experimental colitis in rats.
Topics: Aminopyridines; Analgesics; Animals; Colitis; Diet; Female; Hydrogen Sulfide; Inflammation; Intestin | 2013 |
Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative, anti-inflammatory and anti-apoptotic effects in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Blotting, Wes | 2013 |
Supplemental hydrogen sulphide protects transplant kidney function and prolongs recipient survival after prolonged cold ischaemia-reperfusion injury by mitigating renal graft apoptosis and inflammation.
Topics: Animals; Apoptosis; Dietary Supplements; Disease Models, Animal; Graft Survival; Hydrogen Sulfide; I | 2012 |
Hydrogen sulfide reduces cell adhesion and relevant inflammatory triggering by preventing ADAM17-dependent TNF-α activation.
Topics: ADAM Proteins; ADAM17 Protein; Blotting, Western; Cell Adhesion; Cell Line; Enzyme-Linked Immunosorb | 2013 |
The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells.
Topics: Acute Disease; Animals; Arthritis; Cartilage; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Cytok | 2013 |
Exogenous application of hydrogen sulfide donor attenuates inflammatory reactions through the L-selectin-involved pathway in the cutaneous reverse passive Arthus reaction.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Arthus Reaction; E-Selectin; Gene Deletion; Gene Expr | 2013 |
Hydrogen sulfide eye inflammation; treatment with cortisone.
Topics: Cortisone; Endophthalmitis; Eye Diseases; Hydrogen Sulfide; Inflammation; Sulfides | 1954 |
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio | 2005 |
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio | 2005 |
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio | 2005 |
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio | 2005 |
Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways.
Topics: Airway Resistance; Animals; Bronchi; Bronchoconstriction; Guinea Pigs; Hydrogen Sulfide; Inflammatio | 2005 |
Oxidative stress-dependent conversion of hydrogen sulfide to sulfite by activated neutrophils.
Topics: Animals; Cells, Cultured; Enzyme Inhibitors; Humans; Hydrogen Sulfide; Inflammation; Lipopolysacchar | 2005 |
Hydrogen sulfide and sulfite: novel mediators in the pathophysiology of shock and inflammation.
Topics: Animals; Biomarkers; Humans; Hydrogen Sulfide; Inflammation; Shock; Sulfites | 2005 |
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation.
Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Endothelium, Vascular; Hydrogen Sulfide; Inflammatio | 2006 |
Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB.
Topics: Alkynes; Animals; Cecum; Chemokines; Cystathionine gamma-Lyase; Cytokines; Disease Models, Animal; G | 2007 |
Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; | 2007 |
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.
Topics: Animals; Apoptosis; Echocardiography; Heart Ventricles; Hydrogen Sulfide; Inflammation; Male; Mice; | 2007 |
A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain.
Topics: Alkynes; Animals; Enzyme Inhibitors; Formaldehyde; Glycine; Hydrogen Sulfide; Inflammation; Irritant | 2008 |
Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.
Topics: Acute Disease; Alkynes; Animals; Ceruletide; Cystathionine beta-Synthase; Glycine; Hydrogen Sulfide; | 2008 |
Capsaicin pretreatment modifies hydrogen sulphide-induced pulmonary injury in rats.
Topics: Animals; Capsaicin; Hydrogen Sulfide; Inflammation; Lung; Lung Diseases; Male; Microscopy, Electron, | 1990 |