hydrogen sulfide has been researched along with Injury, Myocardial Reperfusion in 83 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the protective effect of exogenous hydrogen sulfide (H₂S) against myocardial injury after skeletal muscle ischemia/reperfusion (IR) in rats and explore the mechanism." | 7.79 | [Exogenous hydrogen sulfide protects against myocardial injury after skeletal muscle ischemia/reperfusion by inhibiting inflammatory cytokines and oxidative stress in rats]. ( Chen, W; Deng, Z; Li, X; Liu, N; Qi, Y; Xie, X; Yang, J; Zhang, Y, 2013) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 7.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| "Ischemic heart disease is one of the major causes of cardiovascular‑related mortality worldwide." | 6.72 | Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review). ( Gu, Y; Wu, D; Zhu, D, 2021) |
| "Hydrogen sulfide (H(2)S) has been known as a highly toxic gas for several centuries." | 6.47 | Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury. ( King, AL; Lefer, DJ, 2011) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 5.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| "Bioavailability of nitric oxide (NO) and hydrogen sulfide (H2S) is reduced in heart failure (HF)." | 3.83 | Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure. ( Bhushan, S; Bradley, JM; Donnarumma, E; Donnelly, EL; Islam, KN; Lefer, DJ; Otsuka, H, 2016) |
| "To assess the protective effect of exogenous hydrogen sulfide (H₂S) against myocardial injury after skeletal muscle ischemia/reperfusion (IR) in rats and explore the mechanism." | 3.79 | [Exogenous hydrogen sulfide protects against myocardial injury after skeletal muscle ischemia/reperfusion by inhibiting inflammatory cytokines and oxidative stress in rats]. ( Chen, W; Deng, Z; Li, X; Liu, N; Qi, Y; Xie, X; Yang, J; Zhang, Y, 2013) |
| "We investigated the effects of the hydrogen sulfide (H₂S)-releasing derivatives of aspirin (ACS14) and salicylic acid (ACS21) in a rat model of metabolic syndrome induced by glutathione (GSH) depletion, causing hypertension and other pathological cardiovascular alterations." | 3.76 | Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats. ( Berti, F; Del Soldato, P; Manfredi, B; Rossoni, G; Sparatore, A; Tazzari, V; Trivulzio, S, 2010) |
| "PKG activation with tadalafil limits myocardial infarction and preserves LV function through H(2)S signaling." | 3.75 | Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide. ( Abbate, A; Chau, VQ; Hoke, NN; Kukreja, RC; Ockaili, RA; Salloum, FN; Toldo, S; Varma, A, 2009) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 3.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| "Ischemic heart disease is one of the major causes of cardiovascular‑related mortality worldwide." | 2.72 | Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review). ( Gu, Y; Wu, D; Zhu, D, 2021) |
| "Hydrogen sulfide has recently been identified as a potent cardioprotective signaling molecule, which is a highly effective pre- and post-conditioning agent." | 2.47 | Hydrogen sulfide-mediated myocardial pre- and post-conditioning. ( Lefer, DJ; Predmore, BL, 2011) |
| "Hydrogen sulfide (H(2)S) has been known as a highly toxic gas for several centuries." | 2.47 | Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury. ( King, AL; Lefer, DJ, 2011) |
| "Hydrogen sulfide (H2S) is a critical signaling molecule that regulates many physiological and/or pathological processes." | 1.43 | pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury. ( Kang, J; Lefer, DJ; Li, Z; Organ, CL; Pacheco, A; Park, CM; Wang, D; Xian, M; Yang, CT, 2016) |
| "Hydrogen sulfide (H2S) is a signaling molecule with protective effects in the cardiovascular system." | 1.43 | Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms. ( Andreadou, I; Bibli, SI; Chatzianastasiou, A; Daiber, A; Di Lisa, F; Efentakis, P; Kaludercic, N; Manolopoulos, VG; Papapetropoulos, A; Szabó, C; Whiteman, M; Wood, ME, 2016) |
| "Pretreatment with zofenopril significantly reduced myocardial infarct size and cardiac troponin I levels after I/R injury in both mice and swine." | 1.43 | Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability. ( Ali, MJ; Bradley, JM; Cirino, G; Donnarumma, E; Evangelista, S; Goodchild, TT; Islam, KN; Jenkins, JS; Lefer, DJ; Organ, CL; Patel, RA; Polhemus, DJ; Rushing, AM; Scarborough, AL, 2016) |
| "Hydrogen sulfide (H2S) is a signaling molecule which plays regulatory roles in many physiological and/or pathological processes." | 1.42 | Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors. ( Aguilar, HC; Bhushan, S; Kang, J; Lefer, DJ; Li, Z; Organ, C; Otsuka, H; Pacheco, A; Xian, M; Yang, C; Zhao, Y, 2015) |
| "Hydrogen sulfide (H2S) has been demonstrated to protect cardiomyocytes against IR injury, while whether it has anti-autophagy effect has not been known." | 1.42 | Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation. ( Hong, J; Kang, B; Ni, X; Wang, Z; Wu, L; Xiao, J; Xu, J; Zhang, Y; Zhu, X, 2015) |
| " H2S therapy also has been shown to augment NO bioavailability and signaling." | 1.40 | Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. ( Bhushan, S; Bradley, JM; Calvert, JW; Dugas, TR; Elrod, JW; Huang, PL; Islam, KN; Kelley, EE; King, AL; Kondo, K; Lefer, DJ; Nicholson, CK; Otsuka, H; Polhemus, DJ; Tao, YX; Wang, R, 2014) |
| "Hydrogen sulfide (H(2)S) displays an anti-apoptotic activity against myocardial ischemia reperfusion (MIR)." | 1.38 | Hydrogen sulfide protects cardiomyocytes from myocardial ischemia-reperfusion injury by enhancing phosphorylation of apoptosis repressor with caspase recruitment domain. ( Gao, Y; He, C; Jiang, H; Pan, S; Sun, X; Tan, G; Yao, X; Zhang, Y, 2012) |
| "Hydrogen sulfide (H(2)S) displays anti-inflammatory and cytoprotective activities to attenuate myocardial ischemia-reperfusion (MIR)-induced injury, but its role in MIR in diabetics is not known." | 1.37 | The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats. ( Gao, Y; Kang, K; Li, W; Sun, L; Sun, X; Yao, X; Zhang, Y, 2011) |
| "Hydrogen sulfide (H( 2)S) is a biological mediator produced by enzyme-regulated pathways from L-cysteine, which is a substrate for cystathionine-gamma-lyase (CSE)." | 1.36 | L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury. ( Baxter, GF; Elsey, DJ; Fowkes, RC, 2010) |
| "Sudden cardiac arrest (CA) is one of the leading causes of death worldwide." | 1.35 | Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. ( Bloch, KD; Bougaki, M; Elrod, JW; Ichinose, F; Lefer, DJ; Minamishima, S; Minamishima, YA; Sips, PY; Yu, JD, 2009) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 1.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (18.07) | 29.6817 |
| 2010's | 56 (67.47) | 24.3611 |
| 2020's | 12 (14.46) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, D | 2 |
| Gu, Y | 1 |
| Zhu, D | 1 |
| Peleli, M | 1 |
| Bibli, SI | 3 |
| Li, Z | 4 |
| Chatzianastasiou, A | 3 |
| Varela, A | 1 |
| Katsouda, A | 1 |
| Zukunft, S | 1 |
| Bucci, M | 1 |
| Vellecco, V | 1 |
| Davos, CH | 1 |
| Nagahara, N | 1 |
| Cirino, G | 2 |
| Fleming, I | 1 |
| Lefer, DJ | 14 |
| Papapetropoulos, A | 5 |
| Li, HW | 1 |
| Xiao, FY | 1 |
| Liu, X | 2 |
| Yang, R | 1 |
| Bai, W | 1 |
| Xu, X | 1 |
| Bi, F | 1 |
| Hao, Y | 1 |
| Yang, Q | 2 |
| Li, H | 3 |
| Hu, X | 2 |
| Liu, B | 1 |
| Wu, P | 1 |
| Lang, Y | 1 |
| Li, T | 1 |
| Jeddi, S | 1 |
| Gheibi, S | 1 |
| Kashfi, K | 1 |
| Carlström, M | 1 |
| Ghasemi, A | 1 |
| Xia, H | 1 |
| Sharp, TE | 1 |
| Polhemus, DJ | 3 |
| Carnal, J | 1 |
| Moles, KH | 1 |
| Tao, YX | 2 |
| Elrod, J | 1 |
| Pfeilschifter, J | 1 |
| Beck, KF | 1 |
| Zhang, P | 1 |
| Yu, Y | 1 |
| Wang, P | 1 |
| Shen, H | 1 |
| Ling, X | 1 |
| Xue, X | 1 |
| Zhang, Y | 7 |
| Xiao, J | 3 |
| Wang, Z | 3 |
| Zhang, J | 2 |
| Cai, X | 1 |
| Zhang, Q | 2 |
| Li, X | 2 |
| Li, S | 1 |
| Ma, J | 1 |
| Zhu, W | 1 |
| Wei, M | 1 |
| Tu, W | 1 |
| Shen, Y | 1 |
| Liu, J | 1 |
| Lai, X | 1 |
| Yu, P | 1 |
| Sun, X | 3 |
| Wang, Y | 2 |
| Wen, S | 1 |
| Huang, K | 1 |
| Huang, J | 1 |
| Chu, X | 1 |
| Wang, F | 1 |
| Pang, L | 1 |
| Wang, L | 2 |
| Tang, Y | 1 |
| He, H | 1 |
| Wei, W | 1 |
| Ertugrul, IA | 1 |
| van Suylen, V | 1 |
| Damman, K | 1 |
| de Koning, MLY | 1 |
| van Goor, H | 2 |
| Erasmus, ME | 1 |
| Citi, V | 1 |
| Piragine, E | 1 |
| Testai, L | 1 |
| Breschi, MC | 1 |
| Calderone, V | 1 |
| Martelli, A | 1 |
| Zhao, HL | 1 |
| Wu, BQ | 1 |
| Luo, Y | 1 |
| Zhang, WY | 1 |
| Hao, YL | 1 |
| Liang, JJ | 1 |
| Fang, F | 1 |
| Liu, W | 1 |
| Chen, XH | 1 |
| Huang, YQ | 1 |
| Tang, CS | 1 |
| Du, JB | 2 |
| Jin, HF | 2 |
| Ren, L | 1 |
| Wang, Q | 1 |
| Chen, Y | 1 |
| Ma, Y | 1 |
| Wang, D | 2 |
| Ansari, M | 1 |
| Kurian, GA | 3 |
| Wang, W | 1 |
| Liu, H | 1 |
| Lu, Y | 1 |
| Wang, X | 1 |
| Zhang, B | 1 |
| Cong, S | 1 |
| Zhao, Y | 3 |
| Ji, M | 1 |
| Tao, H | 1 |
| Wei, L | 1 |
| Kannan, S | 1 |
| Boovarahan, SR | 1 |
| Rengaraju, J | 1 |
| Prem, P | 1 |
| Peake, BF | 1 |
| Nicholson, CK | 2 |
| Lambert, JP | 1 |
| Hood, RL | 1 |
| Amin, H | 1 |
| Amin, S | 1 |
| Calvert, JW | 3 |
| Shymans'ka, TV | 2 |
| Hoshovs'ka, IuV | 2 |
| Semenikhina, OM | 1 |
| Sahach, VF | 2 |
| Bhushan, S | 6 |
| Yang, C | 2 |
| Otsuka, H | 4 |
| Stein, JD | 1 |
| Pacheco, A | 3 |
| Peng, B | 1 |
| Devarie-Baez, NO | 1 |
| Aguilar, HC | 2 |
| Xian, M | 3 |
| Chen, W | 1 |
| Liu, N | 1 |
| Qi, Y | 1 |
| Yang, J | 1 |
| Deng, Z | 1 |
| Xie, X | 1 |
| Shimanskaia, TV | 1 |
| Strutinskaia, NA | 1 |
| Vavilova, GL | 1 |
| Goshovskaia, IuV | 1 |
| Semenikhina, EN | 1 |
| Sagach, VF | 1 |
| Snijder, PM | 1 |
| de Boer, RA | 1 |
| Bos, EM | 1 |
| van den Born, JC | 1 |
| Ruifrok, WP | 1 |
| Vreeswijk-Baudoin, I | 1 |
| van Dijk, MC | 1 |
| Hillebrands, JL | 1 |
| Leuvenink, HG | 1 |
| Causey, MW | 1 |
| Miller, S | 1 |
| Singh, N | 1 |
| Martin, M | 1 |
| King, AL | 3 |
| Kondo, K | 2 |
| Bradley, JM | 3 |
| Islam, KN | 3 |
| Dugas, TR | 1 |
| Kelley, EE | 1 |
| Elrod, JW | 3 |
| Huang, PL | 1 |
| Wang, R | 1 |
| Dudek, M | 1 |
| Knutelska, J | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Zygmunt, M | 1 |
| Bilska-Wilkosz, A | 1 |
| Iciek, M | 1 |
| Otto, M | 1 |
| Żytka, I | 1 |
| Sapa, J | 1 |
| Włodek, L | 1 |
| Filipek, B | 1 |
| Andreadou, I | 4 |
| Iliodromitis, EK | 3 |
| Rassaf, T | 1 |
| Schulz, R | 1 |
| Ferdinandy, P | 1 |
| Kang, B | 2 |
| Hong, J | 2 |
| Zhu, X | 2 |
| Ni, X | 2 |
| He, B | 1 |
| Xie, H | 1 |
| Xu, Q | 1 |
| Jia, J | 1 |
| Ao, G | 1 |
| Sun, Y | 1 |
| Hu, L | 1 |
| Alkayed, NJ | 1 |
| Wang, C | 1 |
| Cheng, J | 1 |
| Nakano, S | 1 |
| Ishii, I | 1 |
| Shinmura, K | 1 |
| Tamaki, K | 1 |
| Hishiki, T | 1 |
| Akahoshi, N | 1 |
| Ida, T | 1 |
| Nakanishi, T | 1 |
| Kamata, S | 1 |
| Kumagai, Y | 1 |
| Akaike, T | 1 |
| Fukuda, K | 1 |
| Sano, M | 1 |
| Suematsu, M | 1 |
| Peng, L | 1 |
| Yu, X | 1 |
| Penna, C | 1 |
| Granata, R | 1 |
| Tocchetti, CG | 1 |
| Gallo, MP | 1 |
| Alloatti, G | 1 |
| Pagliaro, P | 1 |
| Sun, YG | 1 |
| Wang, XY | 1 |
| Chen, X | 3 |
| Shen, CX | 1 |
| Li, YG | 1 |
| Tzimas, C | 1 |
| Sanoudou, D | 1 |
| Kranias, E | 1 |
| Brouckaert, P | 1 |
| Coletta, C | 1 |
| Szabo, C | 5 |
| Kremastinos, DT | 1 |
| Das, A | 2 |
| Samidurai, A | 2 |
| Hoke, NN | 3 |
| Kukreja, RC | 3 |
| Salloum, FN | 3 |
| Wang, J | 2 |
| Xue, M | 1 |
| Ji, A | 1 |
| Li, Y | 1 |
| Organ, C | 1 |
| Kang, J | 2 |
| Li, C | 1 |
| Hu, M | 1 |
| Lu, H | 1 |
| Deng, J | 1 |
| Yan, X | 1 |
| Xu, J | 1 |
| Wu, L | 1 |
| Ge, N | 1 |
| Liu, C | 1 |
| Li, G | 1 |
| Xie, L | 1 |
| Li, L | 1 |
| Hao, N | 1 |
| Ansari, SB | 1 |
| Jiang, H | 2 |
| Organ, CL | 2 |
| Park, CM | 1 |
| Yang, CT | 1 |
| Efentakis, P | 1 |
| Kaludercic, N | 1 |
| Wood, ME | 2 |
| Whiteman, M | 2 |
| Di Lisa, F | 1 |
| Daiber, A | 1 |
| Manolopoulos, VG | 1 |
| Hu, MZ | 1 |
| Zhou, B | 1 |
| Mao, HY | 1 |
| Sheng, Q | 1 |
| Du, B | 1 |
| Chen, JL | 1 |
| Pang, QF | 2 |
| Ji, Y | 3 |
| Karwi, QG | 1 |
| Torregrossa, R | 1 |
| Baxter, GF | 4 |
| Donnarumma, E | 2 |
| Ali, MJ | 1 |
| Rushing, AM | 1 |
| Scarborough, AL | 1 |
| Evangelista, S | 1 |
| Jenkins, JS | 1 |
| Patel, RA | 1 |
| Goodchild, TT | 1 |
| Donnelly, EL | 1 |
| Yong, QC | 1 |
| Lee, SW | 2 |
| Foo, CS | 1 |
| Neo, KL | 2 |
| Bian, JS | 2 |
| Zhu, JC | 1 |
| Shao, JL | 1 |
| Ma, H | 1 |
| Wang, JK | 2 |
| Jha, S | 1 |
| Gundewar, S | 1 |
| Ramachandran, A | 1 |
| Pattillo, CB | 1 |
| Kevil, CG | 1 |
| Osipov, RM | 1 |
| Robich, MP | 1 |
| Feng, J | 2 |
| Liu, Y | 2 |
| Clements, RT | 2 |
| Glazer, HP | 1 |
| Sodha, NR | 2 |
| Bianchi, C | 2 |
| Sellke, FW | 2 |
| Zhuo, Y | 1 |
| Chen, PF | 1 |
| Zhang, AZ | 1 |
| Zhong, H | 1 |
| Chen, CQ | 1 |
| Zhu, YZ | 1 |
| Horvath, EM | 1 |
| Stahl, GL | 1 |
| Minamishima, S | 2 |
| Bougaki, M | 1 |
| Sips, PY | 1 |
| Yu, JD | 1 |
| Minamishima, YA | 1 |
| Bloch, KD | 1 |
| Ichinose, F | 2 |
| Chau, VQ | 2 |
| Abbate, A | 1 |
| Varma, A | 1 |
| Ockaili, RA | 2 |
| Toldo, S | 1 |
| Wang, XB | 1 |
| Elsey, DJ | 2 |
| Fowkes, RC | 2 |
| Rossoni, G | 2 |
| Manfredi, B | 2 |
| Tazzari, V | 2 |
| Sparatore, A | 2 |
| Trivulzio, S | 1 |
| Del Soldato, P | 2 |
| Berti, F | 2 |
| Lavu, M | 1 |
| Gao, Y | 2 |
| Yao, X | 2 |
| Li, W | 1 |
| Kang, K | 1 |
| Sun, L | 1 |
| Predmore, BL | 2 |
| Ran, K | 2 |
| Tang, ZG | 2 |
| Ding, LP | 1 |
| Li, SF | 2 |
| Chang, YT | 2 |
| Dongó, E | 1 |
| Hornyák, I | 1 |
| Benko, Z | 1 |
| Kiss, L | 1 |
| Stasch, JP | 1 |
| Zlatopolsky, MA | 1 |
| Aragon, JP | 1 |
| Grinsfelder, DB | 1 |
| Condit, ME | 1 |
| Tan, G | 1 |
| He, C | 1 |
| Pan, S | 1 |
| Luan, HF | 1 |
| Zhao, ZB | 1 |
| Zhao, QH | 1 |
| Zhu, P | 1 |
| Xiu, MY | 1 |
| Maslov, LN | 1 |
| Mrochek, AG | 1 |
| Barzakh, EI | 1 |
| Lishmanov, AIu | 1 |
| Gorbunov, AS | 1 |
| Tsibul'nikov, SIu | 1 |
| Sementsov, AS | 1 |
| Prokudina, ES | 1 |
| Johansen, D | 1 |
| Ytrehus, K | 1 |
| Sivarajah, A | 1 |
| McDonald, MC | 1 |
| Thiemermann, C | 1 |
| Hu, Y | 1 |
| Pan, TT | 1 |
| Khin, ES | 1 |
| Moore, PK | 1 |
| Zhu, XY | 1 |
| Yan, XH | 1 |
| Chen, SJ | 1 |
| Xu, G | 1 |
| Zeng, YM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-Term Endogenous Hydrogen Sulfide Upregulation For Vein Graft Disease[NCT05457881] | 226 participants (Anticipated) | Interventional | 2024-03-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for hydrogen sulfide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review).
Topics: Animals; Cardiotonic Agents; Heart; Humans; Hydrogen Sulfide; Ischemic Postconditioning; Myocardial | 2021 |
Role of Hydrogen Sulfide in Myocardial Ischemia-Reperfusion Injury.
Topics: Animals; Carbon Monoxide; Cardiovascular System; Cell Death; Gasotransmitters; Humans; Hydrogen Sulf | 2021 |
Donor Heart Preservation with Hydrogen Sulfide: A Systematic Review and Meta-Analysis.
Topics: Animals; Biomarkers; Cryopreservation; Heart; Heart Function Tests; Heart Transplantation; Humans; H | 2021 |
The Role of Hydrogen Sulfide and H2S-donors in Myocardial Protection Against Ischemia/Reperfusion Injury.
Topics: Animals; Cardiotonic Agents; Humans; Hydrogen Sulfide; Ion Channels; Ischemic Preconditioning, Myoca | 2018 |
[Cardiovascular Regulation by Sulfur-containing Gaseous Signaling Molecules and the Underlying Mechanisms:Updated Research Evidence].
Topics: Animals; Atherosclerosis; Calcium Channels, L-Type; Cardiovascular System; Hydrogen Sulfide; Hyperte | 2017 |
The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning.
Topics: Animals; Cardiotonic Agents; Gasotransmitters; Humans; Hydrogen Sulfide; Ischemic Postconditioning; | 2015 |
Endogenous Cardioprotective Agents: Role in Pre and Postconditioning.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Gasotransmitters; Humans; Hydrogen Sulfide; Ischemic P | 2015 |
Role of Hydrogen Sulfide in Ischemia-Reperfusion Injury.
Topics: Animals; Humans; Hydrogen Sulfide; Myocardial Reperfusion Injury; Organ Specificity | 2015 |
[Role of gas signaling molecule hydrogen sulfide in cardiovascular diseases].
Topics: Animals; Cardiovascular Diseases; Coronary Disease; Humans; Hydrogen Sulfide; Hypertension; Hyperten | 2009 |
Regulation of cardiovascular cell function by hydrogen sulfide (H(2)S).
Topics: Animals; Blood Pressure; Cattle; Humans; Hydrogen Sulfide; Inflammation Mediators; KATP Channels; Mu | 2010 |
Hydrogen sulfide-mediated myocardial pre- and post-conditioning.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Humans; Hydrogen Sulfide; Ischemic Postconditioning; | 2011 |
Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury.
Topics: Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytoprotection; Humans; Hydrogen Sulfide; Li | 2011 |
[Emerging role of hydrogen sulfide in biology].
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain Ischemia; Cardiopulmonary Resuscitation; Heart A | 2010 |
The cardioprotective potential of hydrogen sulfide in myocardial ischemia/reperfusion injury (review).
Topics: Animals; Cardiotonic Agents; Humans; Hydrogen Sulfide; Myocardial Reperfusion Injury; Oxidative Stre | 2011 |
[Trigger mechanism of adaptive phenomenon of ischemic heart postconditioning].
Topics: Adaptation, Physiological; Analgesics, Opioid; Animals; Biological Factors; Carbon Monoxide; Heart; | 2012 |
68 other studies available for hydrogen sulfide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
Topics: Animals; Antioxidants; Cardiovascular System; Cystathionine beta-Synthase; Cystathionine gamma-Lyase | 2020 |
Effect of hydrogen sulfide on cardiomyocyte apoptosis in rats with myocardial ischemia-reperfusion injury via the JNK signaling pathway.
Topics: Animals; Female; Hydrogen Sulfide; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling Syste | 2020 |
Involvement of amylin B-H2S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia-reperfusion-induced myocardial injury in diabetic rats.
Topics: Amylin Receptor Agonists; Animals; Carbenoxolone; Connexin 43; Diabetic Angiopathies; Diabetic Cardi | 2020 |
LncRNA Oprm1 overexpression attenuates myocardial ischemia/reperfusion injury by increasing endogenous hydrogen sulfide via Oprm1/miR-30b-5p/CSE axis.
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Humans; Hydrogen Sulfide; MicroRNAs; Myo | 2020 |
Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High- | 2020 |
Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury.
Topics: Animals; Aorta, Thoracic; Cystathionine gamma-Lyase; Endothelial Cells; Exercise Tolerance; Hydrogen | 2020 |
Hydrogen sulfide restores sevoflurane postconditioning mediated cardioprotection in diabetic rats: Role of SIRT1/Nrf2 signaling-modulated mitochondrial dysfunction and oxidative stress.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Heme Oxygenase (Decyclizing); Hydrogen | 2021 |
Novel controlled and targeted releasing hydrogen sulfide system exerts combinational cerebral and myocardial protection after cardiac arrest.
Topics: Allyl Compounds; Animals; Antioxidants; Brain Ischemia; Cells, Cultured; Delayed-Action Preparations | 2021 |
Liraglutide restores late cardioprotective effects of remote preconditioning in diabetic rats via activation of hydrogen sulfide and nuclear factor erythroid 2-related factor 2 signaling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Ischemic Preconditioning; Ischemic Preco | 2021 |
Exogenous hydrogen sulfide ameliorates high glucose-induced myocardial injury & inflammation via the CIRP-MAPK signaling pathway in H9c2 cardiac cells.
Topics: Animals; Apoptosis; Cells, Cultured; Cold Shock Proteins and Peptides; Glucose; Hydrogen Sulfide; In | 2018 |
Involvement of MicroRNA-133a in the Protective Effect of Hydrogen Sulfide against Ischemia/Reperfusion-Induced Endoplasmic Reticulum Stress and Cardiomyocyte Apoptosis.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Str | 2019 |
Hydrogen sulfide preconditioning could ameliorate reperfusion associated injury in diabetic cardiomyopathy rat heart through preservation of mitochondria.
Topics: Animals; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; Hydrogen Sulfide | 2019 |
Controlled-releasing hydrogen sulfide donor based on dual-modal iron oxide nanoparticles protects myocardial tissue from ischemia-reperfusion injury.
Topics: Allyl Compounds; Animals; Cardiotonic Agents; Cell Line; Delayed-Action Preparations; Ferric Compoun | 2019 |
Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium.
Topics: Alkynes; Animals; Antidotes; Antioxidants; Apoptosis; Cell Hypoxia; Cell Line; Cell Survival; Cystat | 2019 |
Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Diabetes Mellitus, Type 2; Extracellular Signal | 2013 |
[Effect of hydrogen sulfide on isolated rat heart reaction under volume load and ischemia-reperfusion].
Topics: Animals; Cardiotonic Agents; Gene Expression; Heart; Heart Rate; Hydrogen Sulfide; Injections, Intra | 2012 |
Controllable hydrogen sulfide donors and their activity against myocardial ischemia-reperfusion injury.
Topics: Animals; Cell Line; Delayed-Action Preparations; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; M | 2013 |
[Exogenous hydrogen sulfide protects against myocardial injury after skeletal muscle ischemia/reperfusion by inhibiting inflammatory cytokines and oxidative stress in rats].
Topics: Animals; Creatine Kinase, MB Form; Disease Models, Animal; Hydrogen Sulfide; Ischemia; Male; Malondi | 2013 |
[Cyclosporin A-sensitive mitochondrial pore as a target of cardioprotective action of hydrogen sulfide donor].
Topics: Animals; Calcium; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Heart; Hydrogen Sulfide; Hydroxy | 2013 |
Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Carbon Dioxide; Cell Line; Disease Models, Anima | 2013 |
Pharmacologic attenuation of the hyperdynamic response to supraceliac aortic clamping.
Topics: Animals; Aorta; Arterial Pressure; Cardiac Output; Cardiopulmonary Resuscitation; Cardiotonic Agents | 2015 |
[Effects of stimulation and blockade of the synthesis of endogenous hydrogen sulfide at myocardial ischemia-reperfusion].
Topics: Alkynes; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Cysteine; Glycine; Heart; Heart Rat | 2013 |
Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Blotting, Western; | 2014 |
Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Arrhythmias, C | 2014 |
Involvement of miR-1 in the protective effect of hydrogen sulfide against cardiomyocyte apoptosis induced by ischemia/reperfusion.
Topics: Animals; Animals, Newborn; Apoptosis; Disease Models, Animal; Gene Expression Regulation; Hydrogen S | 2014 |
Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cardiotonic Agents; Enzyme Activation; Heart; Hem | 2015 |
Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Fasting; Humans; Hydrogen Sulfide; | 2015 |
[Protective effect of hydrogen sulfide on rats with myocardial ischemia/reperfusion injury and its mechanism].
Topics: Animals; Catalase; Glutathione Peroxidase; Humans; Hydrogen Sulfide; Interleukin-18; Interleukin-1be | 2015 |
Hydrogen sulfide improves cardiomyocytes electrical remodeling post ischemia/reperfusion injury in rats.
Topics: Animals; Atrial Remodeling; Heart; Hydrogen Sulfide; Male; Myocardial Reperfusion Injury; Myocytes, | 2015 |
Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway.
Topics: Animals; Calcium-Binding Proteins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, | 2015 |
Hydrogen sulfide mediates the cardioprotective effects of gene therapy with PKG-Iα.
Topics: Animals; Cells, Cultured; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein K | 2015 |
Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors.
Topics: Animals; Benzamides; Cardiotonic Agents; Cell Line; Drug Design; Heart Ventricles; Hydrogen Peroxide | 2015 |
Hydrogen sulfide and PKG in ischemia-reperfusion injury: sources, signaling, accelerators and brakes.
Topics: Animals; Cyclic GMP-Dependent Protein Kinases; Humans; Hydrogen Sulfide; Myocardial Reperfusion Inju | 2015 |
Hydrogen sulfide preconditioning protects against myocardial ischemia/reperfusion injury in rats through inhibition of endo/sarcoplasmic reticulum stress.
Topics: Animals; Apoptosis; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Humans; Hydrogen Sulfide; | 2015 |
Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation.
Topics: Animals; Animals, Newborn; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Be | 2015 |
Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3β/β-catenin signaling pathway.
Topics: Animals; Apoptosis; beta Catenin; Biomarkers; Blood Pressure; Disease Models, Animal; Glycogen Synth | 2016 |
Hydrogen sulfide modulates sub-cellular susceptibility to oxidative stress induced by myocardial ischemic reperfusion injury.
Topics: Animals; Cardiotonic Agents; Gasotransmitters; Hydrogen Sulfide; Male; Mitochondria, Heart; Myocardi | 2016 |
ER stress-induced apoptosis: A novel therapeutic target in myocardial ischemia and reperfusion injury.
Topics: Apoptosis; Endoplasmic Reticulum Stress; Humans; Hydrogen Sulfide; Myocardial Ischemia; Myocardial R | 2016 |
pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury.
Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Hydrogen-Ion Concentration; Mice; Myocardial Repe | 2016 |
Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms.
Topics: Animals; Cardiotonic Agents; Cell Line; Humans; Hydrogen Sulfide; Male; Mice; Mitochondria, Heart; M | 2016 |
Exogenous Hydrogen Sulfide Postconditioning Protects Isolated Rat Hearts From Ischemia/Reperfusion Injury Through Sirt1/PGC-1α Signaling Pathway.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Coronary Circulation; Heart; Hydrogen Sulfide; In Vitro | 2016 |
Pharmacological postconditioning against myocardial infarction with a slow-releasing hydrogen sulfide donor, GYY4137.
Topics: Animals; Cytoprotection; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Glycoge | 2016 |
Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability.
Topics: Animals; Antihypertensive Agents; Biological Availability; Blotting, Western; Captopril; Cystathioni | 2016 |
Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure.
Topics: Animals; Antioxidants; Cardiotonic Agents; Coronary Occlusion; Heart Failure; Hydrogen Sulfide; Male | 2016 |
Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning.
Topics: Alkynes; Animals; Antibodies, Blocking; Blood Pressure; Chromones; Dimethyl Sulfoxide; Electrocardio | 2008 |
[Interaction between endogenous cystathionine synthase/hydrogen sulfide and heme oxygenase-1/carbon monoxide systems during myocardial ischemic-reperfusion: experiment with rats].
Topics: Animals; Carbon Monoxide; Cystathionine beta-Synthase; Disease Models, Animal; Heme Oxygenase (Decyc | 2008 |
Hydrogen sulfide mediates cardioprotection through Nrf2 signaling.
Topics: Active Transport, Cell Nucleus; Air Pollutants; Animals; bcl-Associated Death Protein; bcl-X Protein | 2009 |
Effect of hydrogen sulfide in a porcine model of myocardial ischemia-reperfusion: comparison of different administration regimens and characterization of the cellular mechanisms of protection.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Survival; Coronary Circulation; Disease Models, Animal; | 2009 |
Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.
Topics: Alkynes; Animals; Apoptosis; Blood Pressure; Blotting, Western; Cardiotonic Agents; Cystathionine ga | 2009 |
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Coronary Vessels; Cytokines; Free Radicals; Hydrogen Sulfide; Imm | 2009 |
Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Brain; Cardiopulmonary Resuscitation; Cardiotonic | 2009 |
Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide.
Topics: Animals; Carbolines; Cyclic GMP-Dependent Protein Kinases; Cystathionine beta-Synthase; Female; Hemo | 2009 |
L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Topics: Alkynes; Analysis of Variance; Animals; Cysteine; Disease Models, Animal; Drug Therapy, Combination; | 2010 |
Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats.
Topics: Animals; Aorta; Aspirin; Blood Pressure; Consciousness; Creatine Kinase; Endothelium, Vascular; Gast | 2010 |
Hydrogen sulfide-mediated cardioprotection: mechanisms and therapeutic potential.
Topics: Animals; Atherosclerosis; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Humans | 2011 |
The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.
Topics: Alkynes; Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Down-Regulation; Enzyme Inh | 2011 |
[Effect of hydrogen sulfide-induced delayed preconditioning on glutathione S-transferase expression during myocardial ischemia-reperfusion in rats].
Topics: Animals; Disease Models, Animal; Glutathione Transferase; Hydrogen Sulfide; Ischemic Preconditioning | 2011 |
Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide.
Topics: Animals; Apoptosis; Benzoates; Cell Survival; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyst | 2012 |
The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability.
Topics: Allyl Compounds; Animals; Antioxidants; Dose-Response Relationship, Drug; Hydrogen Sulfide; Male; Mi | 2012 |
Hydrogen sulfide protects cardiomyocytes from myocardial ischemia-reperfusion injury by enhancing phosphorylation of apoptosis repressor with caspase recruitment domain.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotonic Agents; Casein Kinase II; Caspase 3; | 2012 |
Hydrogen sulfide postconditioning protects isolated rat hearts against ischemia and reperfusion injury mediated by the JAK2/STAT3 survival pathway.
Topics: Animals; Apoptosis; Hydrogen Sulfide; Ischemic Postconditioning; Janus Kinase 2; Male; Myocardial Re | 2012 |
[Effects of hydrogen sulfide preconditioning on myocardial ischemia reperfusion injury in rats].
Topics: Animals; Disease Models, Animal; Hydrogen Sulfide; Ischemic Preconditioning, Myocardial; Male; Myoca | 2012 |
Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiac Output; Decanoic Acids; Glyburide; | 2006 |
The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Topics: Alkynes; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Decanoic Acids; Endotoxins; Enzyme | 2006 |
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.
Topics: Animals; Benzophenanthridines; Cardiotonic Agents; Cell Survival; Chromones; Disease Models, Animal; | 2008 |
The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart.
Topics: Animals; Creatine Kinase; Diclofenac; Epoprostenol; Glutathione; Glyburide; Heart; Hydrogen Sulfide; | 2008 |
H(2)S protects myocardium against ischemia/reperfusion injury and its effect on c-Fos protein expression in rats.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Down-Regulation; Hemodynamics; Hydrogen Sulfide; Male | 2008 |
Exogenous hydrogen sulfide postconditioning protects isolated rat hearts against ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Buffers; Coronary Circulation; Creatine Kinase; Decanoic Acids; Dose-Respon | 2008 |